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D-α-生育酚醋酸酯

1篇引用文献
  • ≥96%
有货

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货号 (SKU) 包装规格 是否现货 价格 数量
V105037-5g
 5g 现货 Stock Image
V105037-25g
 25g 现货 Stock Image
V105037-100g
 100g 现货 Stock Image
V105037-500g
 500g 现货 Stock Image
大包装询价 添加到收藏夹 比较  SDS中文版  DATASHEET
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Endogenous Metabolite (978) Metabolic Enzyme/Protease (4887) 六元杂环化合物 (1702) 萜烯类 (118)
main product photo

基本描述

别名 D-维生素E乙酸酯 | 维生素 E 醋酸酯 | (+)-α-生育酚乙酸酯
英文别名 2-Oxo-1-butanol | UNII-9E8X80D2L0 | CAS-52225-20-4 | (R,R,R)-alpha-Tocopheryl acetate | alpha-Tocopherol acetate | Gevex | Lutavit E 50 | Nanotopes | Tinoderm E | Tocopheryl acetate | Vitamin E acetate | Spondyvit | (+)-.alpha.-Tocopherol acetate | Ephyna
规格或纯度 ≥96%
英文名称 D-α-Tocopherol Acetate
应用 生化研究。用作饲料添加剂，具有抗不妊娠，促进动物生长及动物休内的抗氧化作用。
储存温度 2-8°C储存
运输条件 冰袋运输
产品介绍

微绿黄色或黄色的粘稠状液体。nD20: 1.494-1.498 alpha: 3° (c=2, in ethanol 25°C)

α-生育酚乙酸酯是一种脂溶性维生素 ，同时也是一种维生素E。 它可以通过膳食来源获取。RRRα-生育酚是一种天然形式的α-生育酚。

AI解读

关联靶点（人）

F2 Tclin Thrombin (11687 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ESR1 Tclin Estrogen receptor alpha (17718 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PGR Tclin Progesterone receptor (8562 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA2A Tclin Alpha-2a adrenergic receptor (9450 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
AR Tclin Androgen Receptor (11781 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MAOA Tclin Monoamine oxidase A (11911 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD1 Tclin Dopamine D1 receptor (9720 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PTGS1 Tclin Cyclooxygenase-1 (9233 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A2 Tclin Norepinephrine transporter (10102 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A4 Tclin Serotonin transporter (12625 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADRA1A Tclin Alpha-1a adrenergic receptor (8359 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
OPRM1 Tclin Mu opioid receptor (19785 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
DRD3 Tclin Dopamine D3 receptor (14368 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SLC6A3 Tclin Dopamine transporter (10535 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KCNH2 Tclin HERG (29587 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE3A Tclin Phosphodiesterase 3A (3309 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
TBXA2R Tclin Thromboxane A2 receptor (5717 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
PDE4A Tclin Phosphodiesterase 4A (1943 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
ADORA3 Tchem Adenosine A3 receptor (15931 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
HRH3 Tclin Histamine H3 receptor (10389 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
KDR Tclin Vascular endothelial growth factor receptor 2 (20924 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
MCF7 (126967 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
Skin (286 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GMNN Tbio Geminin (128009 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
RAN Tchem GTP-binding nuclear protein Ran/Importin subunit beta-1/Snurportin-1 (21853 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

关联靶点（其它种属）

Ptpn1 Protein-tyrosine phosphatase 1B (270 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
rep Replicase polyprotein 1ab (378 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID
SARS-CoV-2 (38078 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

名称和识别符

EC号 200-405-4
分子类型 小分子
IUPAC Name [(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] acetate
INCHI InChI=1S/C31H52O3/c1-21(2)13-10-14-22(3)15-11-16-23(4)17-12-19-31(9)20-18-28-26(7)29(33-27(8)32)24(5)25(6)30(28)34-31/h21-23H,10-20H2,1-9H3/t22-,23-,31-/m1/s1
InChi Key ZAKOWWREFLAJOT-CEFNRUSXSA-N
Canonical SMILES CC1=C(C(=C(C2=C1OC(CC2)(C)CCCC(C)CCCC(C)CCCC(C)C)C)OC(=O)C)C
Isomeric SMILES CC1=C(C(=C(C2=C1O[C@](CC2)(C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C)OC(=O)C)C
WGK Germany 1
RTECS GP8280000
PubChem CID 86472
分子量 472.74
Beilstein号 17(5)4,168
Reaxy-Rn 97513

化学和物理性质

密度 0.953
敏感性 对光敏感
折光率 1.494-1.498
比旋光度 24°
闪点(℉) 230 °F
闪点(℃) 110 °C
沸点 184°C
熔点 28°C
分子量 472.700 g/mol
XLogP3 10.800
氢键供体数Hydrogen Bond Donor Count 0
氢键受体数Hydrogen Bond Acceptor Count 3
可旋转键计数Rotatable Bond Count 14
精确质量Exact Mass 472.392 Da
单同位素质量Monoisotopic Mass 472.392 Da
拓扑极表面积Topological Polar Surface Area 35.500 Ų
重原子数Heavy Atom Count 34
形式电荷Formal Charge 0
复杂度Complexity 601.000
同位素原子数Isotope Atom Count 0
定义的原子立体中心计数Defined Atom Stereocenter Count 3
未定义的原子立体中心计数Undefined Atom Stereocenter Count 0
定义的键立体中心计数Defined Bond Stereocenter Count 0
未定义的键立体中心计数Undefined Bond Stereocenter Count 0
所有立体化学键的总数The total count of all stereochemical bonds 0
共价键合单元计数Covalently-Bonded Unit Count 1

安全和危险性（GHS）

WGK Germany 1
RTECS GP8280000
Reaxy-Rn 97513
Merck Index 9495
个人防护装备 Eyeshields,Gloves

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找到5个结果

批号(Lot Number) 证书类型 日期 货号
A2506565 分析证书 21-12-10 V105037
E2224072 分析证书 21-12-10 V105037
E2224076 分析证书 21-12-10 V105037
E2224087 分析证书 21-12-10 V105037
E2224244 分析证书 21-12-10 V105037

此产品的引用文献

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1. Guangfei Wei, Xu Song, Yao Fu, Tao Gong, Quan Zhang.  (2017)  Sustained-release mitochondrial protonophore reverses nonalcoholic fatty liver disease in rats.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  530  (230).  [PMID:28754512] [10.1016/j.ijpharm.2017.07.072]

参考文献

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7. Michael K Dame,Indiradevi Veerapaneni,Narasimharao Bhagavathula,Madhav Naik,James Varani.  (2010-11-26)  Human colon tissue in organ culture: calcium and multi-mineral-induced mucosal differentiation..  In vitro cellular & developmental biology. Animal,  47  ((1)): (32-38).  [PMID:21104039]
8. Ye Zhang,Y A Yousef,Heng Li,T B Melø,K Razi Naqvi.  (2011-06-17)  Comparison of the photochemical behaviors of α-tocopherol and its acetate in organic and aqueous micellar solutions..  The journal of physical chemistry. A,  115  ((29)): (8242-8247).  [PMID:21675787]
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14. Brandon Mapes,Meredith Chase,Ellie Hong,Anton Ludvik,Katy Ceryes,Yong Huang,Sonia S Kupfer.  (2014-02-20)  Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1α,25(OH)2 and 25(OH) vitamin D..  Physiological genomics,  46  ((8)): (302-308).  [PMID:24550213]
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16. Yulin Chen,Xin Liang,Ping Ma,Yaotian Tao,Xiaoqing Wu,Xingxing Wu,Xiaoqing Chu,Shuangying Gui.  (2015-01-13)  Phytantriol-based in situ liquid crystals with long-term release for intra-articular administration..  AAPS PharmSciTech,  16  ((4)): (846-854).  [PMID:25573438]
17. S K Linneen,A R Harding,M T Smallwood,G W Horn,J S Jennings,C L Goad,D L Lalman.  (2015-10-07)  In vivo ruminal degradation characteristics and apparent digestibility of low-quality prairie hay for steers consuming monensin and Optimase..  Journal of animal science,  93  ((8)): (3941-3949).  [PMID:26440174]
18. Benjamin R Fadl,Seth A Brodie,Michael Malasky,Joseph F Boland,Michael C Kelly,Matthew W Kelley,Erich Boger,Robert Fariss,Anand Swaroop,Laura Campello.  (2020-10-23)  An optimized protocol for retina single-cell RNA sequencing..  Molecular vision,  26  (705-717).  [PMID:33088174]
19. Guangfei Wei, Xu Song, Yao Fu, Tao Gong, Quan Zhang.  (2017)  Sustained-release mitochondrial protonophore reverses nonalcoholic fatty liver disease in rats.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,  530  (230).  [PMID:28754512] [10.1016/j.ijpharm.2017.07.072]

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