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| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| V329489-250μg |
250μg |
期货  |
|
| 英文别名 | Venturicidin B|33538-72-6|8S254814I6|(1R,5S,6R,8R,9E,11R,15E,17R)-11-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-1-hydroxy-5-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-6,8,16,18-tetramethyl-4,21-dioxabicyclo[15.3.1]henicosa-9,15,18-trie |
|---|---|
| 规格或纯度 | >95% |
| 英文名称 | Venturicidin B |
| 储存温度 | 2-8°C储存 |
| 运输条件 | 冰袋运输 |
| 产品介绍 |
杀黑星菌素B 是一种抗生素，据报道是一种有效的ATP5（线粒体ATP合酶复合物）抑制剂。该化合物干扰位于膜上的K | + |和H | + | -ATPase通道的F | 0 |部分，并降低通道打开的可能性。通过阻止质子跨膜转移，杀黑星菌素B 导致ATP合酶活性停止。 Venturicidin B is an antibiotic that has been reported to be a potent inhibitor of the ATP5 (mitochondrial ATP synthase complex). This compound interferes with the F|0|portion of membrane-located K|+|and H|+|-ATPase channels and decreases probability of the channels from opening. By blocking proton transfer across the membrane, Venuricidin B causes a halt in ATP synthase activity. |
| IUPAC Name | (1R,5S,6R,8R,9E,11R,15E,17R)-11-[(2R,4R,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-1-hydroxy-5-[(2R,4R,5S,6S)-5-hydroxy-4,6-dimethyl-7-oxononan-2-yl]-6,8,16,18-tetramethyl-4,21-dioxabicyclo[15.3.1]henicosa-9,15,18-trien-3-one |
|---|---|
| INCHI | InChI=1S/C40H66O10/c1-10-32(41)29(8)36(44)26(5)20-28(7)38-27(6)19-23(2)15-16-31(48-35-21-33(42)37(45)30(9)47-35)14-12-11-13-24(3)39-25(4)17-18-40(46,50-39)22-34(43)49-38/h13,15-17,23,26-31,33,35-39,42,44-46H,10-12,14,18-22H2,1-9H3/b16-15+,24-13+/t23-,26+,27+,28+,29+,30+,31+,33+,35-,36-,37+,38-,39+,40+/m0/s1 |
| InChi Key | VIOYQVOQUWWSAB-KEXSXYLYSA-N |
| Canonical SMILES | CCC(=O)C(C)C(C(C)CC(C)C1C(CC(C=CC(CCCC=C(C2C(=CCC(O2)(CC(=O)O1)O)C)C)OC3CC(C(C(O3)C)O)O)C)C)O |
| Isomeric SMILES | CCC(=O)[C@@H](C)[C@H]([C@H](C)C[C@@H](C)[C@@H]1[C@@H](C[C@H](/C=C/[C@@H](CCC/C=C(/[C@@H]2C(=CC[C@@](O2)(CC(=O)O1)O)C)\C)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)O)O)C)C)O |
| PubChem CID | 10032713 |
| 分子量 | 706.9 |
| 溶解性 | Soluble in ethanol, methanol, DMF, DMSO, and water (poor). |
|---|---|
| 密度 | ~1.1 g/cm3(Predicted) |
| 折光率 | n20D1.54 (Predicted) |
| 沸点 | ~823.4° C at 760 mmHg (Predicted) |
| 熔点 | 145-149° C |
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