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落新妇苷

产品编号 A102725 | CAS号 29838-67-3 | Aladdin
Astilbin from Engelhardtia roxburghiana
分析标准品,≥98%
  • 分子式 C21H22O11
  • 分子量450.39
组合的产品项目
货号 规格 库存 价格 数量
A102725-20mg 分析标准品,≥98% 上海(>10)
北方(预计3-5个工作日)
 
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属性

密度 1.7400
存贮条件 储存温度2-8℃

描述

别名 紫杉叶3-O鼠李甲基酸酯;Astilbin Dihydroquercetin; 3-rhamnoside; Taxifolin 3-rhamnoside
生化机理 属黄酮类化合物的植物化学成分,发现于圣约翰麦芽汁和中药制剂中。免疫抑制。抗增殖。
应用 从黄杞中提取的落新妇苷,一种类黄酮的具有抗菌活性的植物化学物质,可用于研究其对多种类型的细胞的药理学和其抗增殖活性的影响。
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参考文献
Xiao-dan Wang, Min-xin Meng, Ling-bo Gao, Ting Liu, Qiang Xu, Su Zeng
This study was designed to understand the transport profiles of astilbin and taxifolin in Caco-2 cell model and their effects on the function and expression of P-glycoprotein. The transport studies we...Read More
S Zou, X Shen, Y Tang, Z Fu, Q Zheng, Q Wang
The effect of astilbin on acute graft rejection was investigated in C57BL/6 mice carrying BALB/c hearts heterotopically transplanted into the neck vessels. Daily treatment with astilbin (50, 125, or 2...Read More
Lvyi L Chen, Zhou Z Lan, Yongqiang Y Zhou, Fei F Li, Xin X Zhang, Chunfeng C Zhang, Zhonglin Z Yang, Ping P Li
Astilbin is a flavonoid compound isolated from the rhizome of Smilax china L. The effects and possible mechanisms of astilbin on hyperuricemia and nephropathy rats were elucidated in this study. Diffe...Read More
O O Mezghrani, X X Ke, N N Bourkaib, B H BH Xu
The main purpose of this research work was to design an optimized self micro-emulsifying drug delivery system (SMEDDS) to enhance the bioavailability of the poor water soluble drug, astilbin. The solu...Read More
Jingqun J Huang, Siwang S Wang, Miaozhang M Zhu, Jianzong J Chen, Xiaoxing X Zhu
Flavonoids are widely found in plants and many of them possess biological and pharmacological activities. In the present study, we assessed the effects of the flavonoids Genistein, Apigenin, Quercetin...Read More
Ping P Li, Sihai S Gao, Wei W Jie, Qilin Q Ao, Yafei Y Huang
This study examined the effect of astilbin on the proliferation of rat aortic smooth muscle cells (RASMCs) induced by angiotensin II (AngII) and explored the possible mechanisms. Cell proliferation mo...Read More
Xi-Cheng He, Qin-Wen Shun, Li-Sha Dong, Xiang-Qian Ge, Hua Zhang, Heng Nong, Xiao-Hua Shen
Astilbin in 28 Smilax glabra (red and white cross-section) from different sources was determined by HPLC. Pharmacodynamics and component of S. glabra was investigated through inflammation experiment (...Read More
Rui-zhi Zhao, Ying Zhao, Li-qing Zhang, Chuan-jian Lu
Sarcandra glaber is a common traditional Chinese medicine used to treat psoriasis and other infectious diseases, isofraxidin and astilbin are the main components of it. In order to study the pharmacok...Read More
T Joseph-Horne, P M Wood, C K Wood, A L Moore, J Headrick, D Hollomon
A new dihydroflavonol glycoside dimer 6,6-bisastilbin (1) and a new nitrile-containing metabolite (Z)-5α,6β-dihydroxy-4β-methoxy-2-cyclohexene-Δ(1,α)-acetonitrile (2), together with three known a...Read More
Yinjie Y Wang, Ruizhi R Zhao, Chuanjian C Lu
To establish a SPE-HPLC method for analyzing astilbin in rats serum and explore the effects of Yinxieling (YXL) prescription and Smilacis Glabrae Rhizoma on the pharmacokinetic characteristics of effe...Read More
Qing-Feng Zhang, Yu-Xian Guo, Guodong Zheng, Wen-Jun Wang
Rhizoma Smilacis Glabrae (RSG) and Rhizoma Smilacis Chinae (RSC) are two herbal materials that belong to the same genera and are both listed in the Chinese Pharmacopoeia. Chemical constituents in the ...Read More
Qing-Feng Zhang, Hon-Yeung Cheung, Ling-Bin Zeng
Rhizoma Smilacis Glabrae (RSG) is a commonly used herbal material in functional food and Traditional Chinese Medicine. A HPLC chromatographic fingerprint was developed for its quality control and spec...Read More
Haiqiu H Huang, Zhihong Z Cheng, Haiming H Shi, Wenbo W Xin, Thomas T Y TT Wang, Liangli Lucy LL Yu
Engeletin, a flavonoid compound, was isolated from the leaves of Engelhardia roxburghiana for the first time, along with astilbin, another flavonoid. The chemical structures of engeletin and astilbin ...Read More
Yong-Jiang YJ Xu, Rica R Capistrano, Liene L Dhooghe, Kenn K Foubert, Filip F Lemière, Sheila S Maregesi, Aliou A Baldé, Sandra S Apers, Luc L Pieters
The extracts of two medicinal plants used in traditionalmedicine against malariawere characterized by means of an LC?SPE?NMR and LC?MS platform. The structure of a series of major constituents from Ba...Read More
Fernando Petacci, Silvia S Freitas, Iguatemy L Brunetti, Najeh M Khalil
Astilbin (5,7,3',4'-tetrahydroxy-2,3-dihydroflavonol-3-?-o-rhamnoside), a flavonoid with a large range of biological activities, was isolated from Dimorphandra mollis, a shrub common to the ...Read More
Rong-Kai RK Lin, Cheng-Hua CH Zhang, Ning N Mu, Qing-Yong QY Yao, Shao-Liang SL Dong, Qiu-Bao QB Ai, Quan-Xing QX Wang
To investigate the effects of astilbin on the expressions of TNF alpha and IL-10 during liver warm ischemia-reperfusion injury....Read More
Chao C Wang, Liping L Zhu, Jingzhi J Yang, Chuangjun C Li, Dongming D Zhang
To study the chemical constituents of the plant of Sarcandra glabra and provide reference for the study of the bioactive substances....Read More
Shao-hua SH Song, Xiao-yun XY Shen, Guo-shan GS Ding, Fang F Liu, Zhen-meng ZM Wang, Zhi-ren ZR Fu
To explore the effects of astilbin on the maturation and immunologic function of mouse bone marrow-derived dendritic cells (DCs)....Read More
Xin-Rong XR Wu, Zhi-Gang ZG Liu, Ren-Liang RL Yan, Wei-Feng WF Sun
To investigate the process of separating and purifying total flavonoids from Smilax glabra....Read More
M D Lucas-Filho, G C Silva, S F Cortes, T R Mares-Guia, V Perpétua Ferraz, C P Serra, F C Braga
Erythroxylum species have several traditional uses in different countries, including the treatment of hypertension. The ethanol extract from E. gonocladum aerial parts, a species endemic to the Brazil...Read More
SH Song
To investigate the protective effects of astilbin on renal ischemia-reperfusion (IR) injury in rats....Read More
Gui-Sheng Li, Wang-Lin Jiang, Xi-Dian Yue, Gui-Wu Qu, Jing-Wei Tian, Juan Wu, Feng-Hua Fu
Astilbin, a flavonoid compound, was isolated from the rhizome of Smilax glabra Roxb. This study was conducted to investigate the efficacy of astilbin on experimental diabetic nephropathy (DN) in vivo ...Read More
Yan Liang, Qiang Xu, An Kang, Yuan Xie, Tong Xie, Li Liu, Haiping Hao, Lin Xie, Guang-ji Wang
We herein describe the development of an LC-MS method for simultaneous determination of astilbin and 3'-O-methylastilbin in rat plasma. A simple liquid-liquid extraction procedure was followed by...Read More
Jinping J Zhao, Ping P Li, Yunfeng Y Zhang, Xianguo X Wang, Qilin Q Ao, Sihai S Gao
The inhibitory effect of astilbin on transplant arteriosclerosis in murine model of thoracic aorta transplantation was examined. Model of rat thoracic aorta transplantation was established. Ninety rat...Read More
Xiang Zhou, Qiang Xu, Jian-Xin Li, Ting Chen
The structures of two flavanonol glycosides isolated from Smilax glabra, named smitilbin and neosmitilbin, have been revised to isoastilbin and neoastilbin, respectively. The revised structures were d...Read More
Xu-hong XH Yang, Huai-biao HB Li, Hong H Chen, Ping P Li, Bo-ping BP Ye
Ten compounds were isolated from the leaves of Rhizophora stylosa, one kind of mangrove plants distributed in the tropical and subtropical areas of the world. Their structures were identified as tarax...Read More
Jianming Guo, Feng Qian, Jianxin Li, Qiang Xu, Ting Chen
BACKGROUND: Astilbin is a flavonoid isolated from the rhizome of Smilax glabra. In a previous study, we revealed its unique immunosuppressive activity, a selective inhibition against activated T lymph...Read More

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