FUEL
·
2025
·
IF 7.5
Bingying Ni,Xiaoyu Pei,Weihua Chen,Meishan Fan,Jun Xie
As a green and efficient pretreatment method, CrCl 3 -catalyzed ethanol pretreatment was employed to depolymerize poplar at various reaction times (5, 10, 20, 30, 50, and 70 min) and temperatures (160, 170, 180, 190, and 200°C) to effectively remove lignin and hemicellulose, thus improving the subsequent enzymatic saccharification efficiency of cellulose. The maximum lignin and hemicellulose removal yields of 94.51 % and 94.78 %, respectively, were achieved when pretreated at 200°C for 20 min. Furthermore, The CrCl 3 -ethanol pretreatment was found to have low dissolution activation energies (18.03 kJ/mol for lignin and 24.15 kJ/mol for hemicellulose) through pseudo-first-order kinetic modeling with ’potential solubility’ integration, demonstrating an energy-efficient synergistic effect conducive to reaction progression. Finally, combining density functional theory (DFT) from the molecular level clarified that hydrogen bonding and conjugated effect of CrCl 3 –ethanol solution and lignin-hemicellulose co-caused high efficiency separation of lignin and hemicellulose. This study integrated kinetic modeling and quantum chemical analysis to unravel the hydrogen-bond-mediated deconstruction mechanism, significantly advancing sustainable biorefinery strategies for efficient biomass valorization.
研究领域:
生物质转化
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绿色化学
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催化化学
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可再生能源
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分子生物学
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反应动力学
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量子化学计算
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产品关联
DOI
高影响因子
Food Bioscience
·
2024
·
IF 4.8
Yu Shen,Baorong Jiang,Zejia Hao,Chenchen Zhang,Zhan Zhang,Qian Wu,Lei Li,Ping Jiang
Both chromium picolinate (Cr-pic) and chromium trichloride (CrCl 3 ) were used as dietary supplements in agricultural products and foodstuffs. We found either these two forms of Cr(III) could ameliorate inflammation and cholestasis in DDC-induced primary sclerosing cholangitis (PSC) mice via regulating bile acid metabolism. Although two Cr(III) are able to alleviate hepatic inflammation by reducing the aggregation of macrophage, Cr-pic exhibiting superior efficacy in decreasing M1 macrophages. Two Cr(III) show inconsistent in regulating intestinal Fxr , but Cr-pic could active intestinal Fxr , promoting intestinal barrier repair. Additionally, both Cr-pic and CrCl 3 enhanced functional abundance of BSH enzymes involved in bile acid transformation, with Cr-pic seems to perturb the abundance of genus more than CrCl 3. In conclusion, this study highlights the efficacy of Cr-pic and CrCl 3 in mitigating inflammation and cholestasis in PSC, Cr-pic is expected superior than CrCl 3 to be supplement ingredient used in PSC treatment via regulating bile acid metabolism.
研究领域:
营养学
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胃肠病学
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药理学
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产品关联
DOI
高影响因子
CATALYSIS TODAY
·
2014
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IF 3.309
Songyan Jia,Kairui Liu,Zhanwei Xu,Peifang Yan,Wenjuan Xu,Xiumei Liu,Z. Conrad Zhang
While chromium trichloride hydrate (CrCl 3 ·6H 2 O) effectively catalyzed the isomerization of glucose into fructose in aqueous solution, a general product selectivity behavior was observed independent of reaction variables such as reaction time, temperature, catalyst loading, halide ion, and initial glucose concentration. By studying the mixed solution of dimethylsulfoxide (DMSO) and water at varied DMSO/H 2 O ratios, it was found that deviation from the general water-phase fructose yield curve, with concomitant 5-hydroxymethylfurfral (HMF) formation, occurred when the fructose concentration in available water became sufficiently high in DMSO rich solvent mix. Therefore, tuning the solvent system was the most effective approach to change the product distribution from CrCl 3 ·6H 2 O catalyzed glucose conversion. The apparent activation energy of glucose conversion in the studied system was estimated to be 58.6 kJ mol −1 . Special attention was also given to gain some mechanistic insights by control experiments with simple model compounds and additives, 13 C NMR and UV–vis spectroscopic analyses.
研究领域:
化学工程
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催化
·
有机化学
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产品关联
DOI
高影响因子
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
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2014
·
IF 2.491
Hai-yan Tang,Qing-gui Xiao,Hong-bin Xu,Yi Zhang
The hypoglycemic activity of chromium methionine (CrMet) in alloxan-induced diabetic (AID) mice was investigated and compared with those of chromium trichloride hexahydrate (CrCl 3 ·6H 2 O) and chromium nicotinate (CrNic) through a 15-day feeding experiment. The acute oral toxicity of CrMet was also investigated in ICR (Institute for Cancer Research) mice by a single oral gavage. The anti-diabetic activity of CrMet was explored in detail from the aspects of body weight (BW), blood glucose, triglyceride, total cholesterol, liver glycogen levels, aspartate transaminase (AST) and alanine transaminase (ALT) levels. The obtained results showed that CrMet had beneficial effects on glucose and lipid metabolism, and might possess hepatoprotective efficacy for diabetes. Daily treatment with 500 and 1000 μg Cr/kg BW of CrMet in AID mice for 15 days indicated that this low-molecular-weight organic chromium complex had better bioavailability and more beneficial effects on diabetics than CrCl 3 ·6H 2 O. CrMet also had advantage over CrNic in the control of AST and ALT activities. Acute toxicity studies revealed that CrMet had low toxicity potential and relatively high safety margins in mice with the LD 50 value higher than 10.0 g/kg BW. These findings suggest that CrMet might be of potential value in the therapy and protection of diabetes.
研究领域:
药理学
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毒理学
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内分泌学
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营养科学
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产品关联
DOI
PubMed
高影响因子
CHEMICAL PHYSICS LETTERS
·
2025
·
IF 3.1
Hainan Zhang,Shuhui Liang,Jianwei Zhang,Xiangge Han,Weiqi Zhou,Jia Gao,Yaohua Li,Shuliang Dou,Yao Li,Feifei Ren
Vanadium dioxide (VO₂) undergoes reversible metal–insulator transitions at critical temperature of 68 °C, rendering it promising for tunable electromagnetic applications. Here, Cr-doped VO₂/Ethyl cellulose (EC) composites are synthesized to raise the transition temperature to 87 °C while retaining shielding effectiveness values of 9.9–26.3 dB (X-band) and 10.2–25.2 dB (Ku-band). Notably, the surface temperature of material plateaus at 70 °C after exposure to one sun for 10 min, preventing passive phase transitions under light exposure. This work provides valuable insights into the design of intelligent electromagnetic interference shielding materials with active thermal regulation capabilities.
研究领域:
材料科学
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电磁功能材料
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智能响应材料
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热管理
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产品关联
DOI
高影响因子
Environmental Technology & Innovation
·
2025
·
IF 7.1
Lei Zheng,Rongzhen Ma,Hong Liu,Changsheng Jiang,Cheng Song
A microfluidic-fluorometric platform integrated with carbon dots was developed for the real-time and sensitive detection of Chromium(VI) (Cr 6 + ). Chitosan and o-Phenylenediamine were used as precursors to synthesize nitrogen-doped carbon dots (OPD-CDs) via a solvothermal method. The OPD-CDs exhibited a monodisperse spherical nanostructure with an average diameter of 3.86 ± 0.09 nm, a quantum yield of 36.77 %, and a surface enriched with amino and carboxyl functional groups. Cr 6+ induced selective fluorescence quenching through a charge transfer mechanism, where electron donation from surface amines suppressed radiative recombination, accompanied by emission red-shift and increased Stokes shift. Furthermore, quenched OPD-CDs was able to restore fluorescence by adding H 2 O 2 . OPD-CDs demonstrated a detection limit of 0.73 μM and a linear range of 0.2–210 μM under the conventional spectrofluorometry. When incorporated into a microfluidic chip, the OPD-CDs integrated platform achieved a rapid response within 1 min, a detection limit of 1.04 μM, and high selectivity against 26 potential interfering ions. Spike-recovery tests in tap and river water samples yielded recoveries of 98.6–104.7 % (RSD ≤ 2.2 %), confirming its practicality for on-site water quality monitoring. This study innovatively merges optoelectronics features of carbon dots with the microfluidic miniaturization, enabling portable and real-time monitoring of Cr 6+ , which highlights critical needs for rapid detection of heavy metals in accidental pollution events and water quality surveillance.
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产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Yechen An,Jinglong Han,Xiaoxu Gao,Ruiyun Ren,Miaomiao Tan,Wenhai Zhang,Xianshi Wang,Haoran Xu,Ruifeng Yan,Wenli Jiang,Yu Tao,Aijie Wang
Advanced treatment of high-salinity organic wastewater from the fine chemical industry is a critical environmental challenge. Graphene oxide (GO) membranes show promise for separating organic compounds and inorganic salts, but their industrial application has been limited by issues with scalability, performance stability, and fouling control. To overcome these barriers, we developed a disc-tube graphene oxide (DTGO) membrane system by optimizing preparation parameters, stacking membrane discs, and integrating in situ fouling mitigation. Our optimized DTGO membrane exhibited exceptional durability during 280-h cross-flow filtration, maintaining stable water flux (∼60 LMH), high rejection of neutral and negatively charged organics (>90 %), and minimal salt retention (<7 %). The DTGO membrane, which can be easily scaled up through disc stacking, showed superior antifouling performance, with a lower flux decline (12.5 %) and irreversible fouling (33 %), compared with GO membranes on other substrates and organic membranes in simulated wastewater. The introduction of hydroxyl radicals further increased the number of hydroxyl functional groups on the membrane surface, enhancing the formation of a protective hydrated layer and reducing flux decline by over 70 % (flux decline 3.5 %). This work demonstrates the potential for large-scale GO membrane deployment, which offers a cost-effective and environmentally friendly solution for sustainable wastewater treatment and resource recovery.
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产品关联
DOI
高影响因子
BIOMACROMOLECULES
·
2025
·
IF 5.4
Zhongyu Li,Liping Pu,Delong Hou,Jun Yan,Qi Zeng,Yi Chen
Cross-linking collagen with high-valent metal ions such as Cr(III), Zr(IV), Fe(III), and Al(III) significantly enhances its physicochemical properties, making collagen-based materials suitable for advanced applications. However, the use of high-valent metal ions is limited by concerns regarding toxicity, redox instability, and low cross-linking efficiency. Here, we present a proof-of-concept demonstrating that nontoxic, stable divalent metal ions (M(II), such as Mg(II), Ca(II)), previously considered ineffective for collagen cross-linking, can facilitate linkage formation within collagen. This is achieved through selective binding of molecularly engineered cucurbit[7]uril to aromatic residues (Phe/Tyr) in collagen, creating tailored coordination sites for M(II). The resulting cross-linking efficiency rivals or exceeds that of high-valent metal ions, with in vitro experiments confirming the nontoxic nature of M(II)-cross-linked collagen. This study expands the repertoire of metal ions capable of cross-linking collagen, addressing the limitations associated with high-valent metal ions and potentially enabling the development of high-performance, biocompatible collagen-based materials.
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产品关联
DOI
PubMed
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2025
·
IF 4.9
Guo Yuxiang,Zhu Jingyun,Sun Changge,Li Yubao,Li Tian,Liu Chao,Wang Qi
Carbon dots (CDs) are suitable for metal ion detection owing to their distinct optical tunability, structural controllability, and varied fluorescence response mechanisms. This research produced blue-fluorescent carbon dots (B-CDs) and red-fluorescent carbon dots (R-CDs) by a one-step microwave-assisted technique. B-CDs specifically recognized Cu 2+ in an aqueous system, while R-CDs exhibited a distinctly selective response to Fe 3+ . Composite carbon quantum dots (B/R-CDs) with purple fluorescence were synthesized by integrating B-CDs and R-CDs, achieving superior dual-metal ion detection capabilities. Using B/R-CDs with dual fluorescence emission peaks, and by monitoring the changes in their ratio fluorescence signals, the designed ion detection system can simultaneously detect Cu 2+ and Fe 3+ in aqueous solutions. The detection process for the two metal ions corresponds to distinct dynamic quenching behaviors of the B/R-CDs. Specifically, Cu 2+ and Fe 3+ form unique coordination structures with the functional groups of the B/R-CDs, leading to different energy level arrangements. This not only enables the discriminative detection of the two metal ions by the B/R-CDs but also ensures immunity from interference by other metal ions. The synthesized dual-emissive B/R-CDs material can be prepared as a single reagent for the quantitative detection of two trace metal ions. Furthermore, test strips and test inks developed with it as the primary component enable semi-quantitative and visual detection.
研究领域:
材料科学
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分析化学
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纳米技术
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环境监测
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传感器与生物传感器
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Lin-Lin Zhang,Zeng Chen,Li Li,Wuying Yang,Dan Wang,Yanping Hong,Kaijie Tang,Jiaxin Hong,Lu-Ying Duan,Limin Lu
Developing a multifunctional sensor that can detect food-related multi-analytes is significant for food safety but remains challenging due to the difficulty of integrating multiple functions into one sensor. Herein, a dual-luminescent europium metal-organic framework (EuMOF) was elaborately synthesized through a simple self-assembly process, during which Eu 3+ coordinated with 2-hydroxyterephthalic acid (HTPA) and 1,10-phenanthroline that delivered strong characteristic fluorescence of HTPA and Eu 3+ . The resultant EuMOF exhibited good detection performance toward Sn 4+ and amitraz with different response behaviors. As for target Sn 4+ , the remarkably enhanced fluorescence from HTPA was observed and the fluorescence for Eu 3+ decreased significantly, which was attributed to the structural disintegration of EuMOF caused by Sn 4+ . Whereas, the presence of amitraz weakened both luminescence of HTPA and Eu 3+ owing to the synergistic function of inner filter effect and photoinduced electron transfer. Furthermore, an intelligent and miniature sensor that incorporated EuMOF-based test paper with color recognition application was exploited for portable visual analyzing Sn 4+ and amitraz in real samples, affording great possibilities for on-site monitoring of food hazards.
研究领域:
材料科学
·
分析化学
·
食品安全
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传感器与生物传感器
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环境监测
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2025
·
IF 4.7
Zhuo Wang,Yihao Zhang,Wenjie Xing,Shen Zhang
In terms of the possible threats for our health, establishing efficacious strategies to determine Cr(VI) in drinking water is of significance. In this work, the fluorescence sensing of Cr(VI) was swimmingly performed based on blue-emitting carbon quantum dots (B-CQDs), which were developed using navel orange peel and N -acetyl-L-cysteine. The maximum emission wavelength was located at 433 nm when the excitation wavelength was 353 nm. After introducing Cr(VI), fluorescence quenching phenomenon was prominently displayed. Based on static quenching mechanism, a selective and sensitive fluorescence detection platform was successfully established. The wider linear range of 0–60 μM and detection limit of 0.084 μM was superior or equal to other methods. Moreover, the practical applications in real water obtained satisfactory recoveries. Taking into account the above analysis, this B-CQDs was very promising for Cr(VI) determination.
研究领域:
环境化学
·
分析化学
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纳米材料
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饮水安全
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荧光检测
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产品关联
DOI
高影响因子
BIOMASS & BIOENERGY
·
2025
·
IF 5.8
Rui Xia,Kai-le Li,Peng Zhao,Xiao-xiao Yang,Jue Wang,Ke-wen An,Qing-hai Li,Hui Zhou,Yan-guo Zhang
Hydrothermal cracking, a thermochemical process operating at 180–220 °C and saturated pressure, offers a promising way to valorize Cr-contaminated agricultural wastes ( e.g. , maize straw, manure) into stable organic fertilizers. Using model compounds (cellulose, xylan, lignin) and three Cr salts (CrCl 3 , Cr(NO 3 ) 3 , Cr(CH 3 COO) 3 ), experiments at 180–220 °C and 30–90 min revealed that hydrothermal cracking achieved >63 % Cr immobilization in solid products, predominantly as stable oxidizable (OF) and residual (RESI) fractions. Nitrate additives (Cr(NO 3 ) 3 ) outperformed chloride and acetate salts, yielding 57.4 % RESI through redox cycling and complexation. Risk assessment (RAC <10 %, RI < 80) confirmed low environmental hazards, with prolonged reaction times (90 min) further reducing bioavailability. Mechanistic studies revealed that Cr immobilization primarily occurs through the interaction between organic matter and Cr, with surface functional group complexation as an additional immobilization pathway. The work provides actionable strategies for tailoring hydrothermal processes to address heavy metal contamination in circular agricultural systems, emphasizing anion-specific optimization for scalable remediation.
研究领域:
环境化学
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农业资源利用
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生物质转化
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重金属污染控制
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热化学转化
·
环境风险评价
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）