Separations
·
2025
·Vol. 12
·期 9
·249
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IF 2.7
Ru Zhao,Xiaoli Li,Yazhou Bao,Wenjun Xu,Chen Xu,Rongrong Wang,Tianlan Xia,Tingli Liu,Ailing Ben
In this investigation, pinocembrin and galangin were efficiently extracted from the male inflorescence ofPopulus albaL. ×berolinensisK. Koch through an enzymatic pretreatment–ultrasonic-assisted strategy (EP-UAS), and the feasibility of their pilot-scale application was validated. The optimal parameters (ethanol volume fraction, cellulase dosage, incubation temperature, incubation time, pH, liquid‒solid ratio, ultrasonic irradiation power during incubation, duty cycle, ultrasonic irradiation power and time during extraction) affecting pinocembrin and galangin yields were systematically explored. The Box–Behnken design (BBD) results provided optimal parameters for the EP-UAS process. Under the optimal conditions, the actual yields of pinocembrin and galangin were 2158.33 ± 0.13 μg/g and 1257.96 ± 0.06 μg/g, respectively. Stability, recovery and reproducibility were determined under the above optimized conditions to evaluate the proposed EP-UAS method. Moreover, laboratory-scale experimental results revealed that the conditions selected via single-factor and response surface experiments were also applicable to pilot-scale production, facilitating industrialization.
研究领域:
天然产物化学
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植物生物技术
·
药物提取工艺
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应用植物学
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生物制药工程
✓ 已验证
产品关联
DOI
高影响因子
Food Chemistry-X
·
2024
·
IF 6.5
Jin-Ru Wang,Xin-Ye Wu,Cheng-Bi Cui,Jin-Feng Bi
Hot air drying (HD), vacuum freeze drying (FD), and pilot-scale freeze drying (PSFD) are extensively used to prepare peach slices. However, the aroma of hot air drying and vacuum freeze-drying is yet to be addressed. In this study, HS-SPME-GC–MS was used to characterize and quantify the volatile compounds in peach slices. First, 33, 36, and 46 volatile compounds were identified and quantified in the HD, FD, and PSFD groups, respectively. PSFD is preferable to HD and FD in terms of the volatile compound types, content, and aroma profiles. PSFD was selected for subsequent permeation and dehydration experiments. The key aroma compounds with an OAV ≥ 1 were found in the PSFD30 group. GC-O analysis was conducted on the PSFD30 group, leading to the preliminary identification of 2-methylbutanal, pentanal, hexanal, 2-hexenal, phenylacetaldehyde, ethyl acetate, 2-methylbutyl acetate, ethyl lactate, linalool, methyl heptenone, and γ-octalactone as distinctive aromas in dried peach slices.
研究领域:
食品科学
·
农业工程
·
化学分析
✓ 已验证
DOI
PubMed
高影响因子
Nature Catalysis
·
2025
·
IF 44.6
Ren Yue,Kong Wei,Li Yang,Zhan Wang,Zhang Chunyu,Miao Yuhang,Yao Bingxin,Li Shengnan,Li Zhenhua,Liu Xiang,Zhan Sheng,Zhou Hua,Shao Mingfei,Duan Haohong
Aqueous electrolysis offers a potential sustainable route for converting biomass derivatives to plastic monomers, such as 5-hydroxymethylfurfural oxidation to 2,5-furandicarboxylic acid (FDCA). However, selective electrosynthesis of high-concentration FDCA at kilowatt scale and ampere-level current density remains an unmet challenge, hindering commercialization. Here we show an engineered solid polymer electrolyte (SPE) reactor to steer Faradaic and non-Faradaic side reactions, achieving FDCA production at an industrially relevant current density (1.5 A cm −2 ) while maintaining high selectivity (97.0%), Faradaic efficiency (88.2%) and concentration (~1.24 M). The stability of the SPE reactor was demonstrated in continuous operation at 0.5 A cm −2 over 140 h. Moreover, a 4.3-kW electrochemical platform was constructed with a scale-out strategy, reaching a pilot-scale FDCA production rate (33 kg per day). This work shows the capability of reactor engineering to enable selective and large-scale production of sustainable chemicals via electrochemical processes.
研究领域:
电化学
·
化学工程
·
可持续化学
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材料科学
·
工业化学
✓ 已验证
产品关联
DOI
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2022
·
IF 7.926
Gang Fu,Lei Ni,Dan Wei,Juncheng Jiang,Zhiquan Chen,Yong Pan
In this study, toluene nitration was scaled up in a meso-scale flow reactor and safety was considered. The exothermic characteristic was demonstrated in a batch calorimeter . Parallel flow was observed in the flow channel and numerical simulation was carried out to show the hydrodynamics . Mass transfer coefficient of the reactor mixer was determined. The effects of flow rates, temperatures and molar ratios on toluene nitration in the flow reactor were analyzed. The conversion of toluene increased from 26% to 86% with the increase of flow rates while the impacts of temperatures and molar ratios were comparatively small. A productivity of 2572 kg/a could be achieved by this meso-scale flow reactor but the highest overtemperature inside the channel was more than 21.3 ∘ C. A comparison between performances of the batch calorimeter and the flow reactor was also presented. The finding of this study can serve as a reference to design inherently safer meso-scale flow reactors for kinetically fast and highly-exothermic reactions.
研究领域:
化学工程
·
反应工程
·
过程安全
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Yi Guo,Rui Wang,Chang Shu,Hong Li,Xin Gao
Reactive distillation (RD) can be effectively used to improve the selectivity of the intermediate product for complex multi-reaction schemes, which involves using distillation to manipulate the column profiles in the RD column (RDC) to attribute the desired reaction and the manipulating reactions to facilitate separation. As the demand for ethyl methyl carbonate (EMC) has increased significantly due to its structural characteristics, the selective synthesis of EMC from the consecutive transesterification of dimethyl carbonate (DMC) and ethanol (EtOH) in the presence of azeotropes between reactants and products was studied as featured reaction schemes. The basic resin catalyst KC161 is utilized to build the kinetic reaction model and supplement the primary data for the process design. The pilot-scale RD experiments are explored to verify the feasibility and the reliability of the model. The impact of critical operation and structure parameters on the conversion and selectivity of the reaction and the azeotropes formed in the system were analyzed. A hybrid distillation process containing an RDC, pressure-swing distillation columns, and a regular distillation column, was designed and optimized based on minimized total annual cost (TAC) using a sequential iterative algorithm. 0. 9997 (mole purity) EMC and 0. 9999 (mole purity) diethyl carbonate (DEC) were obtained with EMC selectivity up to 0.863%.
研究领域:
化学工程
·
工艺化学
·
工业化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Jie Chen,Jinfeng Ling,Bo Sun,Jian Wang,Baoxue Zhou,Xiaohong Guan,Yuankui Sun
Bisulfite-activated permanganate (PM/BS) process has proven to be a promising method for trace organic contaminants (TrOCs) abatement. However, to our knowledge, most previous studies on PM/BS process were limited in synthetic water at lab-scale. Hence, the performance of TrOCs abatement by PM/BS process was investigated in real waters in this study, and for the first time, its feasibility as a pretreatment process was evaluated at pilot-scale. The lab-scale results indicated that almost all tested TrOCs could be completely removed from pure water, while their removal efficiencies varied widely from ∼20 % to ∼90 % in real waters. Correlation analysis suggested that TrOCs abatement decreased linearly with increasing concentration of dissolved organic matter (DOM) and halide ions in real waters. The TrOCs with electron-donating groups were more likely to be decomposed in PM/BS process. The PM/BS pretreatment produced MnO 2 and decreased the aromatic signal of the DOM, which enhanced the removal of DOM during subsequent coagulation-sedimentation processes. Comparing with ozonation, chlorination, and permanganate processes, PM/BS process showed some advantages in terms of TrOCs abatement and operating costs. Furthermore, the pilot-scale experiment confirmed that PM/BS process combined with traditional water treatment processes could achieve excellent TrOCs abatement (greater than 84%).
研究领域:
环境工程
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水处理技术
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）