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OPTICAL FIBER TECHNOLOGY · 2025 · IF 2.7

PDMS-based liquid-core optical fiber fluorescence pressure sensor

Zhoujie Li,Ting Liu,Xuezhi Huang,Qing Yu,Yin Wang,Fang Cheng,Tegoeh Tjahjowidodo

Optical fiber pressure sensors have become indispensable in various fields due to their unique advantages. Traditional sensors based on fiber Bragg gratings or Fabry-Pérot resonators offer high sensitivity and the ability to perform distributed measurements. However, these sensors often suffer from complex manufacturing processes and high costs. To address these challenges, we propose an innovative approach utilizing a polydimethylsiloxane (PDMS)-based liquid-core optical fiber probe for pressure sensing. The fiber probe is prepared by sealing a fluorescent dye solution within the PDMS-based hollow-core fiber and then inserting the end face of a silica optical fiber into it, which only relies on extremely simple fabrication operations and cost-effective materials. When integrated with an excitation laser and a fiber spectrometer, the sensor enables calibration and quantitative detection of pressure based on the correlation between pressure and the fluorescence intensity. The experimental results show that the sensor exhibits a high sensitivity of 400.508 a.u./N and a high resolution of 0.093 N, along with high detection accuracy, good repeatability and stability, rapid dynamic response, and excellent long-term stability within the 0–30 N load range. Moreover, it is capable of effectively monitoring various human activities, such as finger tapping and palm pressure, which are crucial for applications in medical monitoring, wearable devices, human activity monitoring, and smart products.

CAS / MDL: 70131-67-8
研究领域: 光学工程 · 生物医学工程
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OPTICS EXPRESS · 2023 ·Vol. 31 ·期 13 ·21212-21224 · IF 3.8

Multi working mode SPR chip laboratory for high refractive index detection

Zhuo Ren,Chunlan Liu,Yong Wei,Chunbiao Liu,Chen Shi,Xingkai Wang,Yixiong Tang,Rui Wang,Zhihai Liu

The Fiber SPR chip laboratory has become a popular choice in biochemical detection. To meet the needs of different kinds of analytes for the detection range and number of channels of the chip, we proposed a multi-mode SPR chip laboratory based on microstructure fiber in this paper. The chip laboratory was integrated with microfluidic devices made from PDMS and detection units made of bias three-core fiber and dumbbell fiber. By injecting light into different cores of a bias three-core fiber, different detection areas of dumbbell fiber can be selected, enabling the chip laboratory to enter high refractive index detection, multi-channel detection and other working modes. In the high refractive index detection mode, the chip can detect liquid samples with a refractive index range of 1.571-1.595. In multi-channel detection mode, the chip can achieve dual parameter detection of glucose and GHK-Cu, with sensitivities of 4.16 nm/(mg/mL) and 9.729 nm/(mg/mL), respectively. Additionally, the chip can switch to temperature compensation mode. The proposed multi working mode SPR chip laboratory, based on micro structured fiber, offers a new approach for the development of portable testing equipment that can detect multiple analytes and meet multiple requirements.

研究领域: 生物化学检测 · 光学传感 · 微流控技术 · 生物医学工程
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OPTICS LETTERS · 2015 ·Vol. 40 ·期 15 ·3576-3579 · IF 3.292

Microfiber-coupler-assisted control of wavelength tuning for Q-switched fiber laser with few-layer molybdenum disulfide nanoplates

Jin-hui Chen,Guo-qing Deng,Shao-cheng Yan,Cheng Li,Kai Xi,Fei Xu,Yan-qing Lu

Based on the liquid exfoliated method, we obtained the few-layer molybdenum disulfide (MoS2) nanoplates solution. By thermal evaporation method, we directly deposited MoS2 thin film onto the facet of a fiber patch cord. The modulation depth of the film is as high as 29%, and a Q-switched fiber laser was achieved. We also provided a new method to continuously tune the output laser with a tuning sensitivity of ∼5.5  nm/(1%  strain) by controlling the cavity loss with a strained microfiber coupler (MFC).

研究领域: 光学 · 材料科学
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OPTICS LETTERS · 2020 ·Vol. 45 ·期 5 ·1047-1050 · IF 3.714

Tm:YAG ceramic derived multimaterial fiber with high gain per unit length for 2 µm laser applications

Guoquan Qian,Wenlong Wang,Guowu Tang,Xianchao Guan,Wei Lin,Qi Qian,Dongdan Chen,Changsheng Yang,Jiantao Liu,Guiyao Zhou,Shanhui Xu,Zhongmin Yang

In this work, Tm:YAG (Tm:${{\rm Y}_3}{{\rm Al}_5}{{\rm O}_{12}}$) ceramic-derived multimaterial fiber was fabricated by using the molten core method, which has a high gain per unit length of 2.7 dB/cm at 1950 nm. To our knowledge, this is the highest gain per unit length at 2 µm band in similar Tm:YAG-derived multimaterial fibers. A distributed Bragg reflector (DBR) fiber laser was built based on a 10-cm-long as-drawn fiber. The achieved 1950 nm laser, which has a maximum output power of $\sim{240}\;{\rm mW}$ and a slope efficiency of 16.5%, was pumped by a self-developed 1610 nm fiber laser. What is more, an all-fiber-integrated passively mode-locked fiber laser based on the 10-cm-long as-drawn fiber was realized. The mode-locked pulses operate at 1950 nm with duration of $\sim{380}\;{\rm ps}$, and the repetition rate is 26.45 MHz. The results described here indicate that the Tm:YAG ceramic-derived multimaterial fiber with high gain per unit length has promising applications in 2 µm all-fiber fiber lasers.

研究领域: 光学工程 · 材料科学
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IEEE SENSORS JOURNAL · 2023 ·Vol. 23 ·期 18 ·21301-21307 · IF 4.3

An MMF–HCF Reflective SPR Sensor for Simultaneous Measurement of Temperature and Relative Humidity

Chuanxin Teng,Yang Liu,Rui Min,Xuehao Hu,Zujun Qin,Hongchang Deng,Libo Yuan

In this article, a reflective surface plasmon resonance (SPR) sensor based on multimode fiber (MMF)–hollow core fiber (HCF) structure is proposed for simultaneous measurement of temperature and humidity. Along the HCF, two different films, i.e., polyvinyl alcohol (PVA) film and polydimethylsiloxane (PDMS) film are coated on the outer surface to generate two SPR resonances at different wavelengths and achieve the simultaneous measurement function. In order to get a better sensing performance, the length ratio of PVA film and PDMS film, and the PVA coating times are optimized. The experimental results show that the humidity sensitivity of the sensor is 0.6351 nm/% relative humidity (RH) in the RH range of 48%–84% RH, and the temperature sensitivity of the sensor is 1.791 nm/°C in the temperature measurement range of 25 °C–80 °C. The sensor has great potential applications in monitoring the environmental temperature and humidity changes.

研究领域: 光学传感 · 材料科学
✓ 已验证 DOI 高影响因子
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TALANTA · 2022 · IF 6.556

Optical fiber SPR biosensor based on gold nanoparticle amplification for DNA hybridization detection

Like Li,Ya-nan Zhang,Wanlu Zheng,Xuegang Li,Yong Zhao

An optical fiber SPR biosensor based on multimode fiber (MMF)- hollow core fiber (HCF)-MMF is proposed and experimentally confirmed for in situ DNA hybridization analysis. In order to improve the sensitivity of DNA hybridization detection, a sandwich model based on gold nanoparticles (AuNPs) amplification is proposed. In this model, the probe DNA (pDNA) is first modified on the optical fiber sensing area by covalent bonding, and then the biotinylated target DNA (tDNA) is modified on the AuNPs by the high affinity between biotin and streptavidin. Finally, the tDNA on the surface of the AuNPs specifically hybridizes with the pDNA on the optical fiber to form a sandwich model. The near field coupling enhancement between AuNPs and gold film and the high mass ratio of AuNPs give high sensitivity to DNA hybridization detection. Experimental results show that the sandwich-type fiber SPR sensor has a log-linear response in the DNA concentration range of 1 pM–10 nM, and the sensitivity and detection limit are 4.04 nm/log(μM) and 1pM, respectively. This is 1.44 times more sensitive than that without sandwich assay. In addition, the DNA sensor has good specificity and stability, which foreshadows its great application potential in the fields of disease diagnosis, microbial detection and environmental science.

研究领域: 生物传感 · 纳米技术 · 光纤技术 · 生物医学工程 · 分析化学
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ANALYTICA CHIMICA ACTA · 2024 · IF 5.7

Ion imprinted differential modulation system based on enhanced optic-fiber evanescent wave for sensitive and label-free detection of trace nickel ions

Dandan Sun,Chenfei Ma,Guoquan Wang,Lili Liang,Guanjun Wang,Jizhou Wu,Jie Ma

An optical system with low cost monitoring, high sensitivity, strong selectivity and much lower nickel ion (Ni 2+ ) content in tap water than the World Health Organization (WHO) standard (1.19 μM) has been prepared by a simple strategy. This proposed ion-imprinted differential modulation system is based on the Bragg grating (FBG) and microfiber interferometer structure, and the interferometer sensing surface is coated with a polydopamine (PDA)/graphene oxide (GO) film to enhance its sensitivity. Combined with the ion imprinting technique, the microfiber interferometer sensor sensitivity can reach 0.32 nm/nM with the detection limit of 0.66 nM in the low concentration range (Ni 2+ concentration range is 0 nM–100 nM). The experiment not only studies the principle of microfiber interferometer and FBG and their refractive index and temperature performance, but also shows that the FBG power change has a good fitting relationship with wavelength change. In addition, this system performance by the amount of power difference rather than the amount of wavelength shift, which significantly saves on the high cost weight, and size associated with the use of spectral analyzers in traditional inspection systems. This study provides a novel and easy method to develop new sensors with higher comprehensive performance.

研究领域: 环境科学 · 分析化学 · 光学工程
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OPTICS COMMUNICATIONS · 2023 · IF 2.4

High-gain fluoro-sulfo-phosphate-based active fiber for compact low-threshold kilohertz-linewidth single-frequency fiber laser

Yongbao Xiao,Jinzhong Zhu,Ludong Kuang,Yao Ji,Qilai Zhao,Changsheng Yang,Weichao Wang

Single-frequency fiber lasers (SFFLs) are of pivotal importance across optical communication , scientific research and national defense due to their excellent beam quality, long coherent length and low noise. However, the development of high-gain rare-earth-doped glass fibers, which are the key medium used in the SFFLs, remains a critical scientific challenge. To address this issue, we design and fabricate a single-mode fluoro-sulfo-phosphate-based Er 3 + 3+ /Yb 3 + 3+ -codoped glass fiber (denoted as FSP-EYDF). The gain properties and laser performance of the FSP-EYDF have been investigated comprehensively. The results show that the small signal gain coefficient of the home-made FSP-EYDF can reach 4.7 dB/cm at 1535 nm, which is three times higher than that of the silica glass fiber. A short piece of FSP-EYDF with a length of only 1.6 cm has been utilized as a gain medium to support an SFFL operating at 1534.4 nm, which has a threshold of ∼ ∼ 18 mW and a linewidth of 3.15 kHz. This study indicates that high-gain FSP fibers are promising candidates for compact low-threshold narrow-linewidth SFFLs.

研究领域: 光学通信 · 材料科学 · 激光技术
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Optics · 2020 ·Vol. 1 ·期 2 ·202-212 · IF 0

A Miniature pH Probe Using Functional Microfiber Bragg Grating

Yang Ran,Peng Xiao,Yongkang Zhang,Deming Hu,Zhiyuan Xu,Lili Liang,Bai-Ou Guan

Operando and precisely probing aqueous pH is fundamentally demanded, both in chemical and biological areas. Conventional pH probes, subjected to the larger size, are probably unfit for application in some extreme scenarios, such as a trace amount of samples. In this paper, we have further developed the pH sensor that leverages the microfiber Bragg grating with an ultra-compact size down to an order of magnitude of 10−14m3. Using the electrostatic self-assembly layer-by-layer technique, the functional film consisting of sodium alginate, which harnesses a pH-dependent hygroscopicity, is immobilized on the fiber surface. Consequently, the alteration of aqueous pH could be quantitatively indicated by the wavelength shift of the grating resonance via the refractive index variation of the sensing film due to the water absorption or expulsion. The grating reflections involving fundamental mode and higher order mode exhibit the sensitivities of −72 pm/pH and −265 pm/pH, respectively. In addition, temperature compensation can be facilitated by the recording of the two reflections simultaneously. Furthermore, the modeling and simulation results predict the pivotal parameters of the configuration in sensitivity enhancement. The proposed proof-of-concept enriches the toolbox of pH sensor for catering to the need of detection in some extremely small spaces—for example, the living cells or the bio-tissues.Keywords:fiber optics;microfiber;Bragg grating;sodium alginate;electrostatic self-assembly;pH sensor

研究领域: 生物技术 · 化学工程
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Biosensors-Basel · 2023 ·Vol. 13 ·期 10 ·940 · IF 5.4

Tapered Fiber Bioprobe Based on U-Shaped Fiber Transmission for Immunoassay

Xinghong Chen,Lei Xiao,Xuejin Li,Duo Yi,Jinghan Zhang,Hao Yuan,Zhiyao Ning,Xueming Hong,Yuzhi Chen

In this paper, a tapered fiber bioprobe based on Mach–Zehnder interference (MZI) is proposed. To retain the highly sensitive straight-tapered fiber MZI sensing structure, we designed a U-shaped transmission fiber structure for the collection of optical sensing signals to achieve a miniature-insert-probe design. The spectrum responses from the conventional straight-tapered fiber MZI sensor and our proposed sensor were compared and analyzed, and experimental results showed that our proposed sensor not only has the same sensing capability as the straight-tapered fiber sensor, but also has the advantages of being flexible, convenient, and less liquid-consuming, which are attributed to the inserted probe design. The tapered fiber bioprobe obtained a sensitivity of 1611.27 nm/RIU in the refractive index detection range of 1.3326–1.3414. Finally, immunoassays for different concentrations of human immunoglobulin G were achieved with the tapered fiber bioprobe through surface functionalization, and the detection limit was 45 ng/mL. Our tapered fiber bioprobe has the insert-probe advantages of simpleness, convenience, and fast operation. Simultaneously, it is low-cost, highly sensitive, and has a low detection limit, which means it has potential applications in immunoassays and early medical diagnosis.Keywords:optical fiber sensors;tapered fiber bioprobes;Mach–Zehnder interference;immunoassay

CAS / MDL: 919-30-2
研究领域: 光学传感 · 生物医学工程
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SENSORS · 2023 ·Vol. 23 ·期 11 ·5218 · IF 3.9

Microfluidic Biosensor Based on Molybdenum Disulfide (MoS2) Modified Thin-Core Microfiber for Immune Detection of Toxoplasma gondii

Huiji Chen,Binbin Luo,Shengxi Wu,Shenghui Shi,Qin Dai,Zehua Peng,Mingfu Zhao

Simple SummaryA microfluidic biosensor based on a thin-core microfiber coated with molybdenum disulfide for immune detection ofToxoplasma gondiiwas illustrated. The detection range, limit of detection, detection sensitivity, specificity, and clinical properties of the proposed biosensor were explored.AbstractToxoplasma gondii(T. gondii) is a zoonotic parasite that is widely distributed and seriously endangers public health and human health. Therefore, accurate and effective detection ofT. gondiiis crucial. This study proposes a microfluidic biosensor using a thin-core microfiber (TCMF) coated with molybdenum disulfide (MoS2) for immune detection ofT. gondii. The single-mode fiber was fused with the thin-core fiber, and the TCMF was obtained by arc discharging and flame heating. In order to avoid interference and protect the sensing structure, the TCMF was encapsulated in the microfluidic chip. MoS2andT. gondiiantigen were modified on the surface of TCMF for the immune detection ofT. gondii. Experimental results showed that the detection range of the proposed biosensor forT. gondiimonoclonal antibody solutions was 1 pg/mL to 10 ng/mL with sensitivity of 3.358 nm/log(mg/mL); the detection of limit was calculated to be 87 fg/mL through the Langmuir model; the dissociation constant and the affinity constant were calculated to be about 5.79 × 10−13M and 1.727 × 1014M−1, respectively. The specificity and clinical characteristics of the biosensor was explored. The rabies virus, pseudorabies virus, andT. gondiiserum were used to confirm the excellent specificity and clinical characteristics of the biosensor, indicating that the proposed biosensor has great application potential in the biomedical field.Keywords:thin-core microfiber;microfluidic chip;molybdenum disulfide;optical fiber biosensor;toxoplasma gondii

CAS / MDL: 2487-90-3
研究领域: 生物医学工程 · 光学传感 · 寄生虫学
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OPTICS EXPRESS · 2023 ·Vol. 31 ·期 4 ·6203-6216 · IF 3.8

Simultaneous measurement of trace dimethyl methyl phosphate and temperature using all fiber Michaelson interferometer cascaded FBG

Yuhao Chen,Cheng Li,Xiaozhan Yang

All fiber Michaelson interferometer cascaded fiber Bragg grating (FBG) sensor for simultaneous measurement of trace dimethyl methyl phosphate and temperature is proposed. One end of the four-core fiber (FCF) is spliced with a multimode fiber (MMF), the other end is flattened and evaporated with silver film to enhance reflection, and the Michelson interference structure is formed. The grating is engraved in the single-mode fiber (SMF) core and spliced with MMF, then the Michelson interference cascaded FBG, FBG-MMF-FCF sensor is obtained. The sensing film, MnCo2O4 is coated on the surface of FCF, and the structure, elemental composition and morphology of MnCo2O4 were analyzed by X-ray diffraction, X-ray photoelectron spectroscopy and scanning electron microscopy. The sensitivity and the detection limit of DMMP are 86.44 dB/ppm and 0.1767 ppb, respectively. The response/recovery time is about 14/10 s. the temperature sensitivity can be compensated and calculated as 0.069 nm/°C. The sensor has good selectivity and stability, and has a good application prospect in high sensitivity detection of trace DMMP vapor.

CAS / MDL: 20694-39-7
研究领域: 光学传感 · 化学传感 · 光纤技术 · 干涉测量 · 材料科学
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