Despite numerous studies on utilizing polymeric vesicles as nanocapsules, fabrication of tunable molecular pathways on transportable vesicle walls remains challenging. Traditional methods for building penetrated channels on vesicular membrane surface often involve regulating the solvent polarity or photo-cross-linking. Herein, we developed a neat, green approach of stimulation by using CO 2 gas as “molecular drill” to pierce macroporous structures on the membrane of polymersomes. By simply introducing CO 2 /N 2 gases into the aqueous solution of self-assemblies without accumulating any byproducts, we observed two processes of polymeric shape transformation: “gas breathing” and “gas piercing.” Moreover, the pathways in terms of dimension and time were found to be adjustable simply by controlling the CO 2 stimulation level for different functional encapsulated molecules in accumulation, transport, and releasing. CO 2 -breathing and piercing of polymersomes offers a promising functionality to tune nanocapsules for encapsulating and releasing fluorescent dyes and bioactive molecules in living systems and also a unique platform to mimic the structural formation of nucleus pore complex and the breathing process in human beings and animals.
Yan-Li Lu,Yue Ma,Xi-Nan Yang,Jie Gao,Xiao-Qian Chen,Xin Xiao,Pei-Hua Ma
In this paper, a crystalline supramolecular organic framework was constructed based on cyclopentanocucurbit[6]uril (CyP 6 Q[6]) and five benzimidazole compounds [2-aminobenzimidazole (G1), 2-methylbenzimidazole (G2), 2-hydroxymethylbenzimidazole (G3), 2-phenylbenzimidazole (G4), 2-(2-pyridyl) -benzimidazole (G5)] through host-guest interaction, with the Single crystal X-ray diffraction analysis showing that CyP 6 Q[6] and Gn(n=1-5) formed 1:1 host-guest inclusion complexes by hydrogen bonding, respectively. The type of substituent (R group) in the guest determines the mode of interaction with CyP6Q[6], where the benzimidazole rings of G1-G4 are encapsulated in the cavity of CyP6Q[6] with the R group located outside its ports, whereas the R group (pyridinyl group) of G5 enters the cavity of CyP6Q[6] with the benzimidazole ring exposed outside its ports. Interestingly, under the ion-dipole interaction, the inclusion complexes form an '8′ shaped supramolecular organic framework by stacking, and due to the different characteristics of the R group and the binding mode, supramolecular channels with different sizes are formed.
Conventional disposable absorbent hygiene products (DAHPs) currently represent a significant type of solid waste in landfills and are a substantial producer of fiber-based microplastics. In this work, a novel multifunctional cellulose nonwoven (CNW) is reported. The key structural design of this material was achieved by covalently grafting a naturally cycloheptatriene product namely hinokitiol and a silane covalent bridge, successfully transforming the original super hydrophilic substrate into a single-layered, multifunctional material with precisely designed liquid-discharging molecular channels and a tailored, sophisticated hydrophobic/hydrophilic distribution structure. This 3D structure perfectly mimics the conventional adhesive-bonded polyolefin/polyesters laminates comprising a top sheet and a liquid acquisition and distribution layer (ADL). The results of XPS and 1 H NMR indicated the hinokitiol was successfully chemically bonded to the CNW surface. Compared with polyolefin or cotton substrates, the optimal CNW product ( CNW-H-A-2 ) exhibits significantly improved long-term wearing comfort by minimizing the liquid strike-through time (by 26–27%), reducing wet-back amount (by 65–90%), and ensuring an outstanding air-permeability (3011 mm·s - 1 ). Excellent antibacterial properties against Staphylococcus aureus (86.4%) and Escherichia coli (97.3%) were achieved due to the good preservation of the bioactive phenol groups of hinokitiol. Additionally, it can be completely enzymatically-degraded within 24 h. This strategy holds promise as a potential solution for mitigating fiber-based microplastics pollution of DAHPs.
危险品化学品经营许可证（带存储）