SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
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IF 4.831
Xinyue Kou,Li Li,Qian Mei,Wen-Fei Dong,Yucai Wang
Aggregation-induced emission luminogens (AIEgens) have garnered significant attention because of their outstanding photophysical characteristics. AIEgens are used in fluorescence imaging, sensors, tumor treatment, and other related fields. However, the synthese of these AIEgens are relatively complicated and requires expensive raw materials. These drawbacks limit their applications and development to a certain extent. In this study, using cheap and convenient materials, we developed a new type of carbon dots (O-CDs) using a one-step solvothermal method, which has the potential to become a new AIEgen. O-CDs exhibit different fluorescence colors in different solvents, and they exist as monomers in ethylic acid and, ethanol alcohol, etc., exhibiting blue fluorescence. After adding water, the fluorescence of O-CDs gradually turns orange red, because the internal rotation of the disulfide bond molecules is restricted and the AIE effect occurs. Using the unique AIE performance of O-CDs, we fabricated an anti-counterfeiting luminous ink, that can be used for encryption in the reversible double switch mode.
研究领域:
材料科学
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化学
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
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2017
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IF 4.857
Chang Xu,Wan-Ying Zhang,Qiong Ye,Da-Wei Fu
Switchable materials, due to their potential applications in the fields of sensors, photonic devices, digital processing, etc., have been developed drastically. However, they still face great challenges in effectively inducing multiple molecular switching. Herein organic–inorganic hybrid compounds, an emerging class of hydrosoluble optoelectronic-active materials, welcome a new member with smart unique optical/electrical (fluorescence/dielectric) dual switches (switching ON/OFF), that is, [C5H13NBr][Cd3Br7] (1) in the form of both a bulk crystal and an ultraflexible monodirectional thin film, which simultaneously exhibits fast dielectric/fluorescent dual switching triggered by an optical/thermal/electric signal with a high signal-to-noise ratio of 35 (the highest one in the known optical/dielectric dual molecular switches). Additionally, the exceptional stability/fatigue resistance as well as the fantastic extensibility/compactness of thin films (more than 10000 times folding over 90°), makes 1 an ideal candidate for single-molecule intelligent wearable devices and seamlessly integrated optoelectronic multiswitchable devices. This opens up a new route toward advanced light/electric high-performance switches/memories based on organic–inorganic hybrid compounds.
研究领域:
材料科学
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光学工程
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电子工程
✓ 已验证
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
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2025
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IF 4.7
Shan-Shan Hei,Yu Xu,Xue-Wei Pan,Lu Zhai,Zheng-Fang Tian,Xiao-Ming Ren
Multifunctional response materials exhibit potential applications in sensors and optoelectronic devices; however, successfully targeting such materials remains a significant challenge. In this study, we synthesized two zero-dimensional hybrids: (C6H16N)2MnBr1.53Cl2.47 (1, C6H16N = trimethyl propyl ammonium) and (C7H18N)2MnBr1.40Cl2.60 (2, C7H18N = trimethyl butyl ammonium). These compounds were formed by combining pseudoglobular organic ammonium cations with the highly emissive [MnX4]2– (X = Br or Cl) anion. Both compounds undergo order–disorder structural phase transitions, exhibiting thermal hysteresis: 1 at 331 K (heating)/326 K (cooling) and 2 at 383 K/373 K and 445 K/428 K (heating/cooling), respectively. These transitions result in a switchable dielectric behavior. At ambient conditions, both compounds emit the bright characteristic luminescence of the [MnX4]2– anion, with photoluminescence quantum yields (PLQY) of 88.71% for 1 and 94.59% for 2. However, they exhibit thermal quenching at elevated temperatures (∼420 K for 1 and ∼460 K for 2). Near their phase transition temperatures, both compounds also show switchable luminescent properties. Collectively, 1 and 2 represent rare examples of materials exhibiting dual-switchable dielectric and luminescence responses.
研究领域:
材料科学
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无机化学
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物理化学
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光电子学
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固态化学
✓ 已验证
DOI
PubMed
高影响因子
Nanoscale
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2025
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IF 5.1
Beibei Zhang,Xinyi Wang,Min Pan,Xinhao Li,Hong Wang,Yingwei Zhang
In this study, a novel dual-switch fluorescent biosensor based on a bipedal DNAzyme walker was developed for the highly sensitive detection of the tumour biomarker miRNA-141. By exploiting the typically elevated expression levels of miRNA-141 and apurinic/apyrimidinic endonuclease 1 (APE1) in tumour cells, an endogenous dual-gating system was constructed. The presence of both targets was required to initiate an enzyme-free strand displacement reaction, enabling target recycling and the subsequent release of bipedal DNAzyme walker components (D1/D2), which were efficiently isolated using streptavidin-modified magnetic beads. In the presence of Mg2+, the activated DNAzyme walker specifically cleaved fluorophore-labelled substrate strands on gold nanoparticles (AuNPs). Through repeated“walking–cleavage”cycles, fluorescence signals were progressively restored and amplified. By integrating AuNPs as carriers and magnetic separation technology, a cascade dual-amplification system based on non-enzymatic strand displacement and bipedal DNAzyme walking was established, markedly enhancing the detection sensitivity. The biosensor exhibited dual-switch-specific activation, effectively suppressing interference from non-target RNAs and other nucleases, and maintained a low background signal. It demonstrated excellent discrimination between tumour cells and normal cells, and showed good anti-interference performance in spiked serum samples. This study provides a new strategy for the development of high-precision tumour biomarker detection, offering potential for trace analysis in complex biological samples.
研究领域:
生物传感器
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分子诊断
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核酸化学
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肿瘤标志物
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纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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