RSC Advances
·
2016
·Vol. 6
·期 9
·7239-7248
·
IF 3.289
Lizi Huang,Mingyan Liao,Xin Yang,Hao Gong,Liang Ma,Yudan Zhao,Kun Huang
Bisphenols (BPs) are a group of chemicals with two hydroxyphenyl functionalities. BPs analogues including bisphenol A (BPA), bisphenol B (BPB), bisphenol F (BPF), bisphenol S (BPS), bisphenol AF (BPAF), bisphenol AP (BPAP), tetrabromobisphenol A (TBBPA) and tetrachlorobisphenol A (TCBPA) are widely used in the production of plastic materials. There has been a growing concern worldwide about environmental BPs exposure due to their potential adverse effects on human health. Deposition of β-cell toxic misfolded human islet amyloid polypeptide (hIAPP), a hormone biosynthesized and secreted by the pancreatic β-cells, is a cardinal finding in type 2 diabetes mellitus (T2DM). Epidemiological studies suggest BPA exposure is positively associated with the incidence of T2DM, which may be due to the exacerbated toxic aggregation of hIAPP induced by BPA as we previously reported. Here, we demonstrate that bisphenol analogues showed different effects on hIAPP amyloid formation. Unlike the accelerating effects of BPA, four BPs analogues (BPAF, BPAP, TBBPA and TCBPA) showed inhibitory effects on hIAPP aggregation and decreased the membrane disruption capacity of hIAPP. Our results also explained a possible relationship between the spatial structure and the inhibitory capacities of BPs analogues.
研究领域:
环境科学
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毒理学
·
分子生物学
·
内分泌学
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2016
·
IF 0
Xiaobo Wang,Lihua Zhu,Libin Wan,Heqing Tang
Graphene was used to remove low-level environmental endocrines in micro-polluted water with the aid of an investigation about the adsorption of bisphenols at low levels in a very wide range from 0.0005 to 70 mg L −1 . It was found that over the wide concentration range, the adsorption isotherms could be divided into two regions: they followed the Freundlich model in the lower concentration region (correlation coefficient R 2 > 0.99), but obeyed the Langmuir model in the higher concentration region (R 2 > 0.99). This was attributed to the adsorption-induced changes in the morphology of graphene, which created different adsorption sites on the surface of graphene. The obtained values of thermodynamic parameters Δ G 0 , Δ H 0 and Δ S 0 indicated that the adsorption was a spontaneous, exothermic and entropy-decreasing process. The absolute values of these parameters tended to be decreased with increasing bisphenol concentration, suggesting stronger affinity of the binding sites on graphene for the adsorption of the bisphenols at lower concentrations. As confirmed by some characterization and monitoring experiments, the increased bisphenol adsorption decreased the surface grooved regions formed by wrinkles and increased the flat regions. The highly and lowly-wrinkled (or flat) surface states of graphene accounted for the observed two-stage adsorption isotherms.
研究领域:
环境科学
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材料科学
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生物学
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产品关联
DOI
ENVIRONMENTAL POLLUTION
·
2025
·
IF 7.3
Xindong Yang,Chenan Dai,Guoxin Zheng,Shaojie Ding,Juan Wu,Qinghua Zhou,Anping Zhang,Jianqiang Sun
Following the restrictions on bisphenol A (BPA), the production and environmental release of bisphenol analogues (BPs) have increased. However, knowledge about the occurrence of bisphenol analogues other than BPA, especially in farmland soils and edible plants, remains limited. This study investigated the occurrence, contamination characteristics, and human health risks of eight bisphenol analogues in paired soil-plant samples from areas near factories in eastern China. Results indicated that the concentrations of Σ 8 BPs in the collected soil and plant samples ranged from 1.4 to 897.1 ng/g dw and 2.5 to 586.2 ng/g dw, respectively. BPA, bisphenol AF (BPAF), bisphenol F (BPF), and bisphenol S (BPS) were the primary components of BPs, with BPA having the highest detection frequency (74 %). In addition, a positive correlation was observed between the root concentration factor and the log K ow of BPs ( R 2 = 0.471, P < 0.05), whereas the translocation factor exhibited a negative correlation with the log K ow ( R 2 = 0.405, P < 0.05). The hazard index (HI) values of BPs in paired soil-plant samples were <1, suggesting that the current contamination levels of BPs in soils and plants are unlikely to pose significant health risks to humans. However, potential risks from long-term exposure require careful monitoring. This study offers new insights into the spatial distributions and contamination status of BPs in farmland soils and plants, highlighting the environmental behavior and health risks of other bisphenol analogues.
研究领域:
环境科学
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毒理学
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Xianliang Xu,Nan Zhang,Yan Gao,Tao Bao,Sicen Wang
In the present work, a novel composite CCF@UiO-66-NH 2 @TpBD (CCF stands for carboxyl cotton fiber) was fabricated for the extraction and removal of BPs from aqueous samples. Both the UiO-66-NH 2 (MOF) and TpBD (COF) were immobilized on CCF through feasible layer-by-layer and Schiff base reaction, and characterized using field emission scanning electron microscopy (FESEM) equipped with energy dispersive X-ray spectroscopy (EDS), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS) techniques. The CCF@UiO-66-NH 2 @TpBD was packed in pipette tip as micro-column to investigate the adsorption of BPs using a pipette tip solid-phase extraction (PT-SPE) method. Various parameters (sampling flow rate, sample pH, amount of adsorbent, ionic strength, methanol concentration, and flow rate of eluent) affecting the extraction efficiency were optimized. Based on strong π-π conjugation, hydrogen bonding, and hydrophobic interactions, the adsorbent exhibited good extraction and removal capability. A low limit of detection (0.16–0.75 ng/mL) and a high adsorption (4.3–5.6 mg/g) were obtained. Accordingly, the composite CCF@UiO-66-NH 2 @TpBD material was shown to be a suitable adsorbent for the extraction and removal of BPs from aquatic samples due to excellent reusability, reproducibility, and high adsorption capacity.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2017
·
IF 4.162
Zhenzhen Zhang,Jing Zhang,Yang Wang,Yao Tong,Lei Zhang
An extended one-step Stőber method was utilized for the preparation of core@shell spheres, which was made up of a thin layer of resorcinol-formaldehyde (RF) and a silica core. After the carbonization and template-removal process, hollow porous carbon spheres (HPCSs) were synthesized. The structure of HPCSs was characterized by scanning/transmission electron microscopy and N 2 adsorption/desorption isotherms, Fourier transform infrared spectroscopy, energy dispersive X-ray spectrometer and Raman spectroscopy. The results showed that the silica cores were removed successfully and the HPCSs were in good sphere shape with uniform size, high surface areas as well as pores hollow framework structure. Compared with MWCNTs and 3D-graphene, HPCSs exhibited superior extraction ability for nine bisphenols (BPs). HPCSs showed extremely outstanding extraction efficiency for BPs as well as high adsorption capacity due to its hollow porous structure. It was applied as sorbent for the enrichment of nine BPs from environmental water samples and soft drinks prior to high performance liquid chromatographic (HPLC) analysis, obtaining recoveries ranged from 89.6% to 111.5% and the relative standard deviations (RSD) from 0.8% to 6.3%, and the limits of quantification (LOQs) were in the range of 0.183–1.763 μg L −1 .
研究领域:
分析化学
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材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Shu-Ting Cheng,Jin-Yu Qiao,Hong-Ming Zhang,Xiao-Fang Shen,Yue-Hong Pang
Bisphenols (BPs) can migrate from packaging materials into foods, resulting in potentially harmful residues. For example, accumulation of BPs is associated with endocrine disorders. Owing to matrix effects, development of an effective and eco-friendly sample pretreatment would be helpful for BPs detection in beverages packed in plastic containers. In this work, an extraction bar, composed of hollow fiber (HF) functionalized with covalent organic frameworks (COF@Tp-NDA) and 1-ocanol, was prepared for extraction of five BPs simultaneously. The synergistic effect of COF@Tp-NDA and 1-octanol improved the extraction efficiency of BPs from milk-based beverage, juice, and tea beverage. Under optimal conditions, limits of detection ranged from 0.10 to 2.00 ng mL −1 (R 2 ≥ 0.9974) and recoveries ranged from 70.1 % to 106.8 %. This method has the potential to enrich BPs, supporting their accurate determination in complex beverages.
研究领域:
分析化学
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环境科学
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食品科学
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL MONITORING AND ASSESSMENT
·
2025
·Vol. 198
·期 1
·18
·
IF 3
Pan Xiaopeng,Luo Huili,Xiang Yuhang,Li Zekun,Zhao Jia
Bisphenol A (BPA) and its analogues are toxicants that can disrupt the endocrine system. They have been detected in the soil and agricultural products. Bisphenol substitutes (BPs) are distributed throughout the agricultural water system; however, the current status of these BPs entering the soil from irrigation is unclear. In this study, the association of BPA, bisphenol S (BPS), and bisphenol F (BPF) in vegetable soils with irrigation water samples was analyzed. Their accumulation, migration, and influencing factors were explored through simulated irrigation and adsorption tests. Significant correlations ( P < 0.01) were observed, indicating that irrigation water was an important source of BPs in soil. Compared with BPS and BPF, BPA accumulated preferentially in the topsoil (10 cm) and continuously increased with irrigation, resulting in an interception ratio of up to 38.07%. Vertical seepage migration was in the order of BPS > BPF > BPA. Acidic soil (pH = 5), high organic matter content (> 32 mg/g), and micro-agglomerates (< 0.053 mm) promoted the adsorption of these BPs and reduced their migration. Understanding the migration of BPs in soil, particularly in a vertical direction, will assist in controlling their migration. It will also help reduce their accumulation, thereby lowering ecological risks.
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产品关联
DOI
PubMed
高影响因子
Food Analytical Methods
·
2022
·Vol. 15
·期 7
·2036-2047
·
IF 3.498
Gao Ming,Wang Hui,Wang Jun,Wang Xuedong,Wang Huili
Herein, we developed an effervescent reaction-enhanced dispersive liquid–liquid microextraction method for the preconcentration/extraction of bisphenols (BPs) in milk and milky tea samples. This microextraction method was based on the utilization of acidic ionic liquid (AIL) and in situ metathesis reaction (AI-EDLM). Compared to the traditional imidazolium-based ionic liquid, AIL can not only be used as an extractant, but also as an acidic source in the effervescent reaction. Under such a case, it can avoid the use of additional acidic source and also achieve a rapid dispersion effect due to vigorous CO 2 bubbles, which simplify the experimental procedures and decrease the preparation cost of effervescent tablets. By employing the one-factor-at-a-time approach, the main parameters were optimized as follows: 400 mg of [BMIM][HSO 4 ] as extractant, 100 mg of Na 2 CO 3 as alkaline source, 400 mg of Li[NTf] 2 as the ionic-exchange reagent, 4% of NaCl, 5 min of centrifugation and 1.5 mL of ether as the elution solvent. Under optimized conditions, the limits of detection ranged from 0.12 to 0.32 μg L −1 , and the extraction recoveries for BPA, BPB, and BPAF spanned the range of 85.7–106.2% in five kinds of milk samples. Therefore, the AIL ([BMIM][HSO 4 ]) played dual roles, i.e., extractant and pH regulator, in the AI-EDLM procedures. Overall, this proposed method is simple, quick, and environment-friendly with low detection limits and high recoveries for BPs, and thus has excellent application value in the sample pretreatment field in milk and milky tea samples.
研究领域:
分析化学
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环境科学
✓ 已验证
DOI
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2020
·
IF 16.683
Chun-Shuai Cao,Jingzhen Wang,Xiaoyong Yu,Yinqing Zhang,Lingyan Zhu
Bisphenol analogues have been widely used and displayed adverse effects on human beings. Although many photocatalysts displayed remarkable performance in degrading bisphenol A (BPA) or bisphenol F (BPF), it is not clear if they may also efficiently decompose other bisphenol analogues. In this study, Bi 5 O 7 I with satisfactory photocatalytic activity was doped with metal-organic framework (UiO-67) to build up Bi 5 O 7 I/UiO-67 heterojunctions. The heterojunction enhanced the charge mobility and separation of the electron-hole pairs, which was conducive for improving the photocatalytic activity. Consequently, 4:1-Bi 5 O 7 I/UiO-67 realized highly effective degradation of seven bisphenol analogues in one hour. Density functional theory (DFT) calculations uncovered that the reaction rate constant k displayed a positive correlation with the Hirshfeld charge q (N) of tertiary butyl carbon attached with different substituent groups. This provides a prospective heterojunction catalyst to degrade a group of pollutants with similar structures, and sheds light on the structural relationship of degradation efficiency.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2018
·
IF 4.61
Pengfei Wu,Zongwei Cai,Hangbiao Jin,Yuanyuan Tang
Polyvinyl chloride (PVC) plastics are easily embrittled and decomposed to microplastics in an aquatic environment. The plasticizers such as bisphenol A (BPA), bisphenol S (BPS) and their analogues might be released and adsorbed by the PVC microplastics causing consequential pollution to the ecosystem. Herein, a systematic study was performed to determine the adsorption mechanisms of five bisphenol analogues (BPA, BPS, BPF, BPB and BPAF) on PVC microplastics. The maximum adsorption efficiency reached 0.19 ± 0.02 mg·g −1 (BPA), 0.15 ± 0.01 mg·g −1 (BPS), 0.16 ± 0.01 mg·g −1 (BPF), 0.22 ± 0.01 mg·g −1 (BPB), and 0.24 ± 0.02 mg·g −1 (BPAF) at PVC dosage of 1.5 g·L −1 . The kinetics study shows that the adsorption processes can be divided into three stages including external mass transport, intraparticle diffusion and dynamic equilibrium. The isotherm modeling shows a better fit of the adsorption results to the Freundlich isotherm compared to the Langmuir model. The thermodynamic study indicates the adsorption of all bisphenols as exothermic processes. Furthermore, the adsorption mechanisms of bisphenols were explicated intensively, with respect to hydrophobic interactions, electrostatic forces, and noncovalent bonds. A positive effect of hydrophobic interactions was identified for bisphenols adsorption on PVC microplastics, but an obvious inhibition by electrostatic repulsions was revealed for BPF due to its ionization in the neutral solution. In addition, noncovalent bonds (hydrogen and halogen bonds) may promote the adsorption of bisphenols on PVC microplastics. Finally, the desorption and competitive adsorption of five bisphenol analogues on the microplastics were provided together with a perspective for future works.
研究领域:
环境科学
·
化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 44
·期 4
·1485-1492
·
IF 3.288
Shuo Li,Huizhong Si,Jianshu Li,Mengtian Jia,Xiaohong Hou
In this study, a metal organic framework/chitosan/polyethylene oxide foam (MOFs/CS/PEO foam) was successfully designed and fabricated, in which polyethylene oxide (PEO) acted as a porogen to increase the adsorption capacity of the MIL-53(Al)/CS foam. The inherent characters, e.g. strength and stability, of the modified foam were also significantly improved. As MIL-53(Al) exhibits the highest adsorption capacity in both computations and experiments among the candidates such as MIL-53(Al), MIL-53(Fe), MIL-101(Cr), MIL-101(Fe), UiO-66(Zr), and MIL-100(Fe), the MIL-53(Al)/CS/PEO foam was chosen as a sorbent to develop a vortex assisted solid phase extraction method for the first time. The efficient method was then successfully applied for the extraction of a trace amount of five bisphenols (bisphenol A, bisphenol B, bisphenol C, bisphenol AF and bisphenol F) in beverages and water with plastic containers, followed by high-performance liquid chromatography-fluorescence detection. A satisfactory result of methodology validation was obtained. Under the optimum conditions, the linear ranges were 0.1–20 μg L−1 with the correlation coefficient (r2) ranging from 0.9943 to 0.9977. The method detection limits were in the range of 0.019–0.065 μg L−1. And the recoveries ranged from 72.68 to 104.6% with relative standard deviations smaller than 9.1%. The proposed hybridization foam was durable and environmentally friendly, since it still maintained adsorption ability after being recycled ten times. The novel method proposed in this work could provide technical support in the fields of environmental protection and food safety.
研究领域:
环境科学
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食品安全
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分析化学
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产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2023
·
IF 13.6
Siqi Wu,Siyao Liu,Zhiming Wang,Yinguang Chen,Guohua Zhao
Bisphenol analogues (BPs) are typical environmental hormones with endocrine-disrupting effects and reproductive toxicity requiring analysis and monitoring in complex aquatic environments. However, the presence of various co-existing contaminants makes the accurate determination of total BPs difficult. To address this challenge, there is a strong need to obtain a group-targeting binder to specifically detect a class of BPs. In this work, for the first time we have identified the group-targeting BPs-aptamer with similar affinities for multiple structurally and qualitatively similar BPs. Base mutations were introduced into an aptamer specific to bisphenol A (BPA) and utilized molecular docking calculations to identify a group-targeting aptamer capable of binding BPs, including BPA, bisphenol B (BPB), bisphenol E (BPE) and bisphenol F (BPF) with binding constants in the range of 2.0 × 10 6 ∼ 2.7 × 10 6 / M. In addition, an electrochemical aptamer-based sensor (aptasensor) was constructed for highly sensitive and comprehensive analysis of a class of BPs. This aptasensor demonstrated remarkable anti-interference performance against co-existing contaminants at concentrations up to 100-fold and achieved an impressive detection limit of 6.7 pM. This innovative approach of engineering a group-targeting BPs-aptamer is important for the comprehensive analysis of BPs, providing insights into identification and monitoring a class of pollutants.
研究领域:
分析化学
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环境科学
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生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）