SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Ying Hu,Lingmin Lu,Shiman Guo,Xiaolan Wu,Jiayi Zhang,Chunsong Zhou,Haiyan Fu,Yuanbin She
A reversible fluorescent probe Pyr-1 was developed by integrating pyrene and oxime functional groups and applied for visual detection of Cysteine (Cys). By featuring three binding sites, Pyr-1 exhibited selective fluorescence quenching response towards Fe 3+ through the formation of 1:1 coordination complex. The ensemble Pyr-1-Fe 3+ was further applied to detect Cys. Among the various test species, Cys induced unique fluorescence enhancement through the decomplexation process. The detection of Cys exhibited a fluorescence “turn-off-on” phenomenon within 50 s and reversible cycle performed up to at least 32 times. The detection limit was calculated as 0.446 µM. Due to the excellent stability in wide pH range (2−11), Pyr-1-Fe 3+ was successfully applied in detection of Cys in diverse food samples. In practical applications, an obvious fluorescent color difference was observed on paper-based device modified by Pyr-1-Fe 3+ , which was convenient and could be used for on-site evaluation of Cys in food samples.
研究领域:
分析化学
·
食品科学
·
生物化学
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Qingling Zhao,Xiang Li,Xiaotong Wang,Zehao Zang,Heyan Liu,Lanlan Li,Xiaofei Yu,Xiaojing Yang,Zunming Lu,Xinghua Zhang
The surface functional groups of carbon dots (CDs) play a significant role in the luminescence performances, but it is still unclear about the effects of special groups on the luminescence mechanism since there are different groups on the surface of prepared CDs. Here, electrochemical method was adopted to synthesize initial CDs and graphite rods served as raw materials, and initial CDs were only modified with amino groups to regulate their surface states, which lead to the blue, green and red luminescence for the modified CDs. The amino groups with different contents are only introduced on the surface of CDs without affecting carbon core. With the increased contents of amino groups, the luminescence spectra of CDs can be successfully modulated from blue to red emission. In addition, the blue emitting carbon dots (B-CDs) have a specific response to Cu 2+ ions and can be applied as a fluorescent probe to detect Cu 2+ ions in the solution. Moreover, the addition of DL-serine can restore the blue emission of B-CDs quenched by Cu 2+ ions. Therefore, the B-CDs have great potential application as a fluorescent reversible ion detector.
研究领域:
材料科学
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分析化学
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纳米技术
✓ 已验证
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2016
·
IF 2.693
Zhenhu Song,Fang Wang,Jian Qiang,Zhijie Zhang,Yahui Chen,Yong Wang,Wei Zhang,Xiaoqiang Chen
We developed a simple and sensitive hydrogel sensor in the form of microspheres by using fluorescence probe encapsulated within a hydrogel matrix for the detection of Hg 2+ . The traditional fluorescence probes suspended in solution are not transportable and recoverable. To overcome these disadvantages, we devised poly(ethylene glycol) diacrylate-based hydrogel microspheres in which fluorescence probe ( R19S ) was embedded at high density. The functionalized hydrogel microspheres were prepared by combining a microfluidic device with UV light . The hydrogel microspheres-based sensor exhibited good selectivity to Hg 2+ among various metal ions and high sensitivity with a detection limit of 90 nM. Furthermore, after binding with Hg 2+ , the R19S encapsulated hydrogel microspheres can be separated from testing samples easily and treated with the solution containing KI to remove Hg 2+ and realize reusable detection. The current work may offer a new method for Hg 2+ recognition with a more efficient manner.
研究领域:
分析化学
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环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2022
·Vol. 14
·期 45
·4730-4738
·
IF 3.532
Chao Chen,Chenxi Wang,Pengcheng Zhao,Jin Zhang,Yongjun Hu,Junjie Fei
A novel facile, quick, and temperature-controlled sensor was constructed based on a polystyrene-poly-N,N-diethyl acrylamide-polystyrene (PS-PDEAM)/carboxylated multi-walled carbon nanotube (MWCNT) composite modified glass carbon electrode. The sensor achieves acetaminophen (AP) reversibility through better temperature sensitivity. PS-PDEAM shrinks when the temperature exceeds its lower critical temperature (LCST). When AP molecules pass through the modified interface, the electron transfer rate is accelerated, and the sensor is turned on. In the off state, the electrochemical response of AP cannot be detected. Under ideal experimental conditions, for composite modified films, there is a wide detection range of AP between 1.5–85.1 μM and 85.1–235.1 μM, and the limit of detection of acetaminophen is as low as 0.57 μM (S/N = 3). This method has been successfully applied to the determination of AP in tablets, and shows high stability, good reproducibility and excellent anti-interference ability. The on-off sensor opens up a wide range of possibilities for the use of temperature-sensitive polymers in electro-catalysis, sensors, and environmental pollutant monitoring.
研究领域:
分析化学
·
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2025
·
IF 4.7
Yaning Wang,Junyu Ren,Rongjin Zeng,Fenmin Cheng,Yuanqiang Hao,Shu Chen,Peisheng Zhang
The rational development of a versatile tool capable of rapid and cyclic detection of nerve agents is of great significance due to their extreme toxicity. Herein, we report a reversible colorimetric and ratiometric fluorescent probe ( DMC-Py ) for rapid and cyclic detection of nerve agent mimic (diethyl chlorophosphate, DCP) base on intramolecular charge transfer (ICT) mechanism. When exposed to DCP, the pyridine unit of DMC-Py is quickly converted to pyridinium salt (<7 s); meanwhile, the toxic DCP is simultaneously transformed into non-toxic neutral phosphate ester, accompanying by a rapid color change from light green to dark yellow, and fluorescence change from cyan to orange red because of the enhancement of the ICT effect. The probe exhibits high sensitivity and specificity in solution. For DCP vapour detection, the filter paper shows a distinct color transition, precisely quantifiable via a smartphone application. A linear correlation between the R/G ratio and 0 – 10.24 ppm DCP has been established, vividly illustrating its potential for field applications. The addition of triethylamine to the corresponding DMC-PyH product can regenerate the original DMC-Py . Alternate exposure of DMC-Py to DCP and triethylamine can induce the color and dual-emission changes in both solution phase and filter paper, thereby achieving the reversibility of the probe. This strategy provides a critical framework for rationally designing reversible ratiometric fluorescent probes for cyclic detection of nerve agents.
研究领域:
化学传感
·
环境科学
·
生物医学工程
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2015
·
IF 4.097
Lu Jing Chai,Jin Zhou,Hui Feng,Jing Jing Lin,Zhao Sheng Qian
A convenient and reversible nanoswitch with the assistance of cerium ions based on aggregation and disaggregation of carbon quantum dots was developed to achieve highly sensitive detection of pyrophosphate ions. Two states including aggregation state and disaggregation state corresponding to fluorescence on and off signaling can be readily switched in a reversible way. The aggregation state is resulted from large nanoassembly formed by carbon quantum dots and cerium ions due to their strong complexation affinity. The disaggregation state comes from competitive combination between cerium ion and pyrophosphate ion. The PPi ion severs as the external chemical stimulus to CQDs/Ce(III) nanoassembly, and its quantity is responsive to fluorescence intensity of the sensing system. Quantitative evaluation of PPi in a broad range from 0.3 to 29.7 μM with the detection limit of 0.1 μM can be realized in this way. The PPi detection in human HeLa cells was also assessed, and fluorescence switching between ON and OFF can be readily observed in response to presence and absence of PPi.
研究领域:
分析化学
·
生物传感
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2023
·
IF 4.3
Xinya Yao,Ying Li,Yuetian Guo,Keli Zhong,Lijun Tang,Xiaomei Yan
Reversible detection of bisulfite (HSO 3 - ) and hydrogen peroxide (H 2 O 2 ) is highly desirable in biology and food safety owing to their redox pair function in biological systems and their utilization in food industry. In this work, a ratiometric fluorescent probe ( TPA-Y ) with aggregation-induced emission (AIE) properties based on triphenylamine fluorophore was designed and synthesized for reversibly monitoring of HSO 3 - /H 2 O 2 . Reaction of HSO 3 - with TPA-Y can result in ratiometric fluorescence changes ( I 444 / I 629 ), and the emission spectrum blue shift reaches 185 nm, which can effectively avoid spectral overlap. Meanwhile, the solution color changed obviously from orange to colorless, enabling naked eye detection of HSO 3 - . TPA-Y was capable of quantitatively detect HSO 3 - in sugar and wine samples with the recovery rates ranging from 94.52 to 102.18%. In addition, TPA-Y is suitable to prepare paper strips and anti-counterfeiting ink for HSO 3 - detection. In addition, the original TPA-Y can be released after the addition product ( TPA-Y-HSO 3 - ) is oxidized by H 2 O 2 , and the HSO 3 - /H 2 O 2 redox cycle can repeat for at least six times. The probe TPA-Y can be applied to fluorescence imaging of reversible and dynamic interconversion between HSO 3 - and H 2 O 2 in living MCF-7 cells.
研究领域:
生物化学
·
食品安全
·
分析化学
✓ 已验证
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Min Chen,Jun Wang,Qianbo Zhang,Jinsheng Zhang,Zhiming Chen,Rongguo Sun
Conventional Hg 2+ visual sensors are unsustainable, hindering their practical application for improved water quality and health. In order to address this challenge, herein, N, S co-doped carbon nanodots (NS-CDs) were prepared and well characterized, presented the fluorescent monitoring for Hg 2+ over other metal ions with the limit of detection (LOD) of 0.47 µM. Next, the CDs were successfully modified by thymine without any fluorescence labelling (referred to as T-NS-CDs). The sensitivity to Hg 2+ cloud be noticeable enhanced due to the formation of T-Hg 2+ -T specific base pairs. Accordingly, the LOD was calculated with values as low as 1.56 nM. Furthermore, Hg 2+ could be released and complexed with antidote (meso-2,3-dimercaptosuccinic acid) (DMSA-Hg 2+ ), being the responsible for the reversible interconversion between T-Hg 2+ -T and DMSA-Hg 2+ . Interestingly, the proposed sensing system also applies to the fluorescent sensing for Hg 2+ in tap water with satisfactory recoveries (96.97 %–101.38 %, RSD < 2 %). Thus, by simply combination of elemental doping and surface functionalization, the surface state and functionalities of CDs could be tailorable, endowing the fluorometric sensing towards Hg 2+ in environmental system.
研究领域:
环境科学
·
分析化学
·
纳米材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2016
·Vol. 51
·期 23
·10350-10360
·
IF 2.302
Yu Runhui,Li Yan,Tao Furong,Cui Yuezhi,Song Weiqiang,Li Tianduo
Conjugated polymer P, which was synthesized by introducing 9,9-diphenylfluorene and thiophene units into the backbone of poly(fluorenylene ethynylene), showed high sensitivity in detecting nitroaromatics. A double-layer sensor, named P-PS/GEL, was prepared by electrospinning technique using polymer P, polystyrene (PS), and gelatin (GEL). A nanofibrous membrane from the mixture of PS and P as the top layer (P-PS) served as the sensing layer for detecting nitroaromatics (NACs). A gelatin nanofibrous membrane as the bottom layer (GEL) served as porous scaffold for the top layer. Therefore, apart from transferring into the top layer directly from above, the NACs molecules could also approach the top sensing layer through the bottom porous layer. This double-layer conformation greatly improved the permeability of the P-PS layer. As a result, the double-layer sensor exhibited a greater quenching efficiency ( Q
f ) of 75 % than that of the single-layer P-PS (55 %). Importantly, the sensor showed good reversibility of quenching process after being exposed to saturated DNT vapor for 6 cycles.
研究领域:
分析化学
·
材料科学
·
纳米技术
·
传感器技术
·
环境监测
·
分子识别
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）