REACTIVE & FUNCTIONAL POLYMERS
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2025
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IF 5.1
Jinhan Zhang,Caixia Yuan,Bingqian Wang,Yuan Sun,Yongsheng Xiang,Lihua Wu,Yanjun Cui,Zhenbin Chen
The recovery of valuable elements from spent copper–indium–gallium–diselenide solar cells has been a topic of considerable interest. In this study, based on the elemental ratios in the leachate of spent solar cells, a multi-template thermos-responsive imprinted polymer (GIS-TIIP) was prepared by combining thermo-responsive technology and imprinted technology. This polymer was used for the simultaneous and proportional selective separation and purification of gallium, indium, and selenium from the leachate. The structure and performance of GIS-TIIP were systematically characterized through Fourier Transform Infrared Spectroscopy, Scanning Electron Microscopy-Energy Dispersive Spectrometry, Transmission Electron Microscopy, Brunauer-Emmett-Teller surface area and pore size analysis, Thermogravimetric Analysis, X-ray Photoelectron Spectroscopy, and Inductively Coupled Plasma-Atomic Emission Spectroscopy. The structure of GIS-TIIP responded to temperature changes. At 35 °C, maximum adsorption capacities were 0.0162 mmol/g for Ga 3+ , 0.0671 mmol/g for In 3+ , and 0.1001 mmol/g for SeO 3 2− . At 25 °C, maximum desorption ratios were 72.65 % for Ga 3+ , 75.33 % for In 3+ , and 69.34 % for SeO 3 2− . The ratio of maximum adsorption capacities for the three target ions (1: 4.142: 6.179) was close to the ratio of the molar amounts of template substances added during the synthesis (1:4:8). The adsorption process of GIS-TIIP fitted better with the pseudo-first-order kinetic model and the Langmuir model. When GIS-TIIP was applied to the diluted leaching solution, the purity of the target elements increased from 55.99 % to 80.98 % after a single adsorption/desorption cycle. The ratio of gallium, indium, and selenium was found to be 1: 4.263: 5.509, indicating the potential for alloy recovery and recycling. After 10 cycles of repeated use, GIS-TIIP still retained 75.71 % of its original adsorption capacity.
研究领域:
材料科学
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环境工程
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化学工程
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DOI
高影响因子
Journal of Materials Chemistry B
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2021
·Vol. 9
·期 14
·3192-3199
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IF 6.331
Yuanchen Liu,Yujian Liu,Zhiming Liu,Jonathan P. Hill,Azhar Alowasheeir,Zhigang Xu,Xingtao Xu,Yusuke Yamauchi
Traditional analysis methods are susceptible to interference caused by the complexity of sample matrices, and detector surface fouling arising from nonspecific adsorption of microorganisms (in biological samples) which leads in particular to a gradual loss of sensitivity. Imprinted materials can be used to effectively reduce interference originating in the matrices. However, the poor reproducibility and multicomponent quantification of trace antibiotics represent significant challenges to the detection process. Meanwhile, the high biological risk presented by bacterial antibiotic immunity and the persistence of antibiotics in foodstuffs, especially meat, both caused by the overuse of sulfonamide antibiotics, remain urgent issues. Here, we present the first example of a method for the accurate quantification of trace sulfa antibiotics (SAs) based on multi-template imprinted polymers (MMIPs). Levels of multiple SAs have been simultaneously successfully quantified by applying MMIP extraction coupled with UPLC-MS/MS analysis. This method shows excellent linearity of detection in the range of 0.1–500 μg L−1, and ultrasensitivity with low limits of detection of 0.03 μg L−1. The maximum SA residue recovered from sample tissues by using MMIPs was 5.48 μg g−1. MMIP-coupled UPLC-MS/MS quantification of SAs is an accurate and repeatable method for the monitoring of SA accumulation in mouse tissue samples. It also provides an effective strategy for the tracking and quantification of drugs in other biological samples.
研究领域:
分析化学
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环境科学
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食品安全
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DOI
PubMed
高影响因子
Polymers
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2017
·Vol. 9
·期 12
·653
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IF 3.364
Chenghong Sun,Jinhua Wang,Jiaojiao Huang,Dandan Yao,Chong-Zhi Wang,Lei Zhang,Shuying Hou,Lina Chen,Chun-Su Yuan
The feasible, reliable and selective multi-template molecularly imprinted polymers (MT-MIPs) based on SBA-15 (SBA-15@MT-MIPs) for the selective separation and determination of the trace level of ginsenoside Rb1(Rb1), ginsenoside Rg1(Rg1) and notoginsenoside R1(R1) simultaneously from biological samples were developed. The polymers were constructed by SBA-15 as support, Rb1, Rg1, R1as multi-template, acrylamide (AM) as functional monomer and ethylene glycol dimethacrylate (EGDMA) as cross-linker. The new synthetic SBA-15@MT-MIPs were satisfactorily applied to solid-phase extraction (SPE) coupled with high performance liquid chromatography (HPLC) for the separation and determination of trace Rb1, Rg1and R1in plasma samples. Under the optimized conditions, the limits of detection (LODs) and quantitation (LOQs) of the proposed method for Rb1, Rg1and R1were in the range of 0.63–0.75 ng·mL−1and 2.1–2.5 ng·mL−1, respectively. The recoveries of R1, Rb1and Rg1were obtained between 93.4% and 104.3% with relative standard deviations (RSDs) in the range of 3.3–4.2%. All results show that the obtained SBA-15@MT-MIPs could be a promising prospect for the practical application in the selective separation and enrichment of tracePanax notoginsengsaponins (PNS) in the biological samples.Keywords:multi-template molecularly imprinted polymers;SBA-15;Panax notoginsengsaponins;separation and determination;solid-phase extraction
研究领域:
药物分析
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生物化学
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DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2025
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IF 4
Xiuqi Lang,Shanchao Fu,Huizhen Zhao,Wenhui Lu,Deyi Zhu,Shan Cao,Lingxin Chen,Jinhua Li
Multi-template molecularly imprinted materials (mt-MIPs) were prepared by surface imprinting and sealed into porous nylon membrane as micro-solid phase extraction (μ-SPE) device, coupled with high performance liquid chromatography (HPLC) to simultaneously extract and determine five typical chlorophenols (CPs) in leather matrices. By using well-prepared mesoporous silica modified multiwalled carbon nanotubes (MWCNTs@mSi) as supporting materials, and the mixture solution of five CPs as templates, the imprinted layer containing recognition sites of the CPs were formed via free radical polymerization. The as-prepared mt-MIPs were characterized by SEM, TEM, FT-IR and TGA, and the adsorption properties were investigated including static, dynamic and selective adsorption, showing high adsorption capacity of 39.15‒71.43 mg g −1 and rapid mass transfer rate (within 30 min). Parameters affecting the extraction efficiency of membrane protected μ-SPE were optimized, including the type of membrane, amount of adsorbent, type and volume of desorption solvent, desorption time and salt effect. The established mt-MIPs-μ-SPE-HPLC method demonstrated satisfactory linearity of 2.0‒200 µg L −1 , high sensitivity with LODs of 0.17‒0.52 µg L −1 , and high enrichment factor (70.6‒144). Consequently, the method was successfully applied to the analysis of five CPs in tannery wastewater, finished leather and wet blue samples. Spike recoveries ranged from 73.00%‒115.2%, with RSDs of 0.28%‒11.4%, and matrix interference was examined to be negligible. The developed method proved viable for the simultaneous extraction and quantification of trace CPs in complex leather matrices.
研究领域:
分析化学
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环境科学
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DOI
PubMed
高影响因子
Frontiers of Environmental Science & Engineering
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2021
·Vol. 15
·期 5
·1-12
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IF 4.357
Zeng Guolong,Liu Yiyang,Ma Xiaoguo,Fan Yinming
Antibiotic contamination of the water environment has attracted much attention from researchers because of their potential hazards to humans and ecosystems. In this study, a multi-template molecularly imprinted polymer (MIP) modified mesoporous silica coated magnetic graphene oxide (MGO@MS@MIP) was prepared by the surface imprinting method via a sol-gel process and was used for the selective, efficient and simultaneous removal of tetracyclines (TCs), including doxycycline (DC), tetracycline (TC), chlorotetracycline (CTC) and oxytetracycline (OTC) from water. The synthesized MIP composite was characterized by Fourier transform infrared spectroscopy, transmission electron microscope and thermogravimetric analysis. The adsorption properties of MGO@MS@MIP for these TCs were characterized through adsorption kinetics, isotherms and selectivity tests. The MIP composite revealed larger adsorption quantities, excellent selectivity and rapid kinetics for these four tetracyclines. The adsorption process was spontaneous and endothermic and followed the Freundlich isotherm model and the pseudo-second-order kinetic model. The MGO@MS@MIP could specifically recognize DC, TC, CTC and OTC in the presence of some chemical analogs. In addition, the sorption capacity of the MIP composite did not decrease significantly after repeated application for at least five cycles. Thus, the prepared magnetic MIP composite has great potential to contribute to the effective separation and removal of tetracyclines from water.
研究领域:
环境科学
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材料科学
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分析化学
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2016
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IF 3.926
Wenhui Lu,Xiaoyan Wang,Xiaqing Wu,Dongyan Liu,Jinhua Li,Lingxin Chen,Xinshen Zhang
Novel multi-template molecularly imprinted polymers (mt-MIPs) with six phenolic compounds as the template, namely phenol, 4-chlorophenol (4-CP), 2,4,6-trichlorophenol (2,4,6-TCP), 2,4-dichlorophenol (2,4-DCP), 2-chlorophenol (2-CP) and 2,6-dichlorophenol (2,6-DCP), were prepared by precipitation polymerization and used as the adsorbents of solid-phase extraction (SPE), and coupled with capillary electrophoresis (CE) for the simultaneous selective extraction, separation and determination of trace phenolic compounds in water samples. The resultant mt-MIPs exhibited uniform spherical morphology, large specific surface area and high thermal stability, and offered high selectivity towards the six template phenolic compounds. Various parameters affecting the molecularly imprinted SPE (MISPE) efficiency were investigated in detail, and excellent CE separation was realized within 7 min. Good linearity was obtained in the range of 1–200 μg L −1 for phenol and 4-CP, and 1–300 μg L −1 for 2,4,6-TCP, 2,4-DCP, 2-CP and 2,6-DCP. High sensitivity was attained with low limits of detection and quantification ranging from 0.17 to 0.31 μg L −1 and 0.57 to 1.03 μg L −1 , respectively. Satisfactory recoveries for spiked reservoir water, river water, tannery wastewater and tap water samples were achieved in the range of 82.13–105.63% with relative standard deviations within 1.68–6.96%. The developed MISPE-CE method proved practically feasible for simultaneous selective extraction/enrichment, separation and sensitive determination of multiple targets in complicated aqueous matrices.
研究领域:
环境科学
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分析化学
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DOI
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2024
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IF 3.8
Wenhui Lu,Shanchao Fu,Xiuqi Lang,Huizhen Zhao,Deyi Zhu,Shan Cao,Lingxin Chen,Jinhua Li
Magnetic multi-template molecularly imprinted polymers (M-mt-MIPs) were successfully synthesized by surface imprinting and multi-template imprinting strategy, using polydopamine coated magnetic multi-walled carbon nanotubes as supporting materials, five typical chlorophenols (CPs) as templates, methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linker. Compared to non-imprinted polymers (NIPs), the as-prepared M-mt-MIPs showed high adsorption capacity (32.58‒80.63 mg g −1 ), rapid mass transfer and specific selectivity for the five targeted CPs, which were applied as magnetic solid-phase extraction (MSPE) adsorbents. Parameters affecting MSPE efficiency were detailed investigated, such as adsorbents dosage, sample pH, extraction time, type and volume of desorption solvent and salt effect. Combined with HPLC-DAD, a simple, rapid and sensitive method was established, showing good linearity (2‒200 μg L −1 ), low limits of detection (0.32‒0.49 μg L −1 ), and high enrichment factors (35.2‒108). The developed M-mt-MIPs-MSPE-HPLC method was applied to enrich and determine CPs in tannery wastewater, wet-blue and crust leather, and satisfactory spiking recoveries were attained in the range of 73.95‒109.7% with relative standard deviations (RSDs) of 2.13–8.48%. This study provided a new alternative material and method to rapid simultaneously extract and analyze low concentration of typical CPs in complicated matrices.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
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2025
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IF 4
Tingfan Tang,Xuesong Li,Ziwei Xu,Jiayu Zhao,Yaqin Zhan,Yixing Li,Lijun Li,Hao Cheng,Yuhong Tian,Wenyi Huang,Jun Feng
In this study, magnetic multi-template molecularly imprinted polymers (MMIPs) are successfully synthesized. The synthesis is carried out by a multi-template surface imprinting strategy using mesoporous silica-coated magnetic graphene oxide as the support material, matrine (MT), oxymatrine (OMT) and sophocarpine (SC) as the templates, 4-vinylbenzoic acid as the functional monomer, and ethylene glycol dimethacrylate (EDGMA) as the cross-linker. The MMIPs were characterized using Fourier-transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and transmission electron microscopy. The maximum adsorption capacity of the prepared MMIPs was found to be 9.01, 20.87, and 7.76 mg/g for MT, OMT, and SC, respectively, demonstrating higher adsorption capacity compared to the non-imprinted polymers (MNIPs). Furthermore, MMIPs were utilized as adsorbents for magnetic solid-phase extraction (MSPE) in conjunction with pressurized capillary electrochromatography (pCEC) for the simultaneous separation and detection of MT, OMT, and SC in the Chinese herbal medicine substrate sophora. The factors affecting the extraction efficiency of MSPE, including the type of elution solvent, amount of adsorbent, pH of the sample solution, elution time, and eluent volume, were optimized. The MMIPs-pCEC method demonstrated a satisfactory linear response within the concentration range of 1–50 μg/mL for the three alkaloids, with correlation coefficients ranging from 0.9923 to 0.9972 and limits of detection ranging from 0.09 to 0.73 μg/mL. The findings of the present study demonstrate that MMIPs have important applications in the analysis of active ingredients in traditional Chinese medicine.
研究领域:
中药分析
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材料科学
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分析化学
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产品关联
DOI
PubMed
高影响因子
ANALYTICAL LETTERS
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2017
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IF 1.15
Xiuping He,Jiangtao Wang,Xiaoqi Mei
A multitemplate molecularly imprinted polymer was synthesized using fragments similar to gonyautoxins 1 and 4 including 2,4,6-triaminopyrimidine, 4-hydroxy-2-butanone, and imidazole as dummy templates by bulk polymerization. Scanning electron microscopy and infrared spectroscopy showed a porous structure and the formation of organic groups in the imprinting process of the polymer. One millilitre of 0.1 mol L−1 acetic acid and 1 mL of 95% methanol were the optimized washing and eluting solutions during the molecularly imprinted solid-phase extraction. The adsorption capacity of the multitemplate molecularly imprinted polymer was lower than for the monotemplate molecularly imprinted polymer prepared in a previous study in seawater in which Alexandrium tamarense and Alexandrium minutum were cultivated. This result may due to the inappropriate combination of the dummy template fragments in the synthesis resulting in the unfitness of the imprinting sites for gonyautoxins 1 and 4. In general, it is inappropriate to use fragments with the similar parts to the analyte as the dummy templates. However, this work indicated the optimal molecularly imprinted polymer for the selective extraction of gonyautoxins 1 and 4.
研究领域:
环境科学
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分析化学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Xiaowen Xie,Xiaoguo Ma,Lihui Guo,Yinming Fan,Guolong Zeng,Mengyuan Zhang,Jing Li
A novel multi-templates molecularly imprinted polymer (MIP) was prepared on the surface of mesoporous silica coated magnetic graphene oxide (MGO@mSiO 2 ), and applied for the rapid and selective detection of alkylphenol compounds including bisphenol A (BPA), 4-tert-octylphenol (4-tert-OP) and 4-nonylphenol (4-NP) in water. The synthesized composite was characterized by Fourier transform infrared spectrometer, vibrating sample magnetometer, transmission electron microscopy and Brunauer-Emett-Teller surface area analyzer. The MIP showed high adsorption capacity, good selectivity and fast kinetic for these alkylphenols. The maximum adsorption capacities of the MIP for BPA, 4-tert-OP and 4-NP were 16.81, 35.97 and 61.73 mg g −1 , respectively, which were significantly higher than those of the non-molecularly imprinted polymer (NIP) due to the imprinting effect. The adsorption of alkylphenols reached equilibrium within 30 min, and followed pseudo-second-order kinetic model and Langmuir model well. The MIP exhibited good sorption selectivity towards BPA, 4-tert-OP and 4-NP, and could be reused 5 times. Furthermore, a new method for ultrasensitive determination of BPA, 4-tert-OP and 4-NP in water by high performance liquid chromatography was developed, using MIP-based magnetic solid-phase extraction coupled with dispersive liquid-liquid microextraction. Under the optimum conditions, the limits of detection (LODs) for BPA, 4-tert-OP and 4-NP were 0.013, 0.010 and 0.010 μg L −1 , respectively. The proposed method was used to the detection of BPA, 4-tert-OP and 4-NP in real water samples, with spiked recoveries of 81.5–104.1% and relative standard deviations (RSDs) of 1.0–7.6%, indicating the multi-templates MIP could be a promising adsorbent for separation and analysis of alkylphenols.
研究领域:
环境科学
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分析化学
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DOI
高影响因子
TALANTA
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2025
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IF 6.1
Rongrong Xing,Tingyu Xue,Huangjin Li,Yifei Zhou,Xuan Chen,Shuang Hu
Cinnamic acid derivatives, a crucial group of active components in traditional Chinese medicines (TCMs), encompass chlorogenic acid, caffeic acid, 4-hydroxycinnamic acid, ferulic acid, and cinnamic acid. These compounds exhibit a wide array of pharmacological activities, such as free radical scavenging, antioxidation, antibacterial effects, and antitumor activity. However, traditional separation and detection methods often suffer from poor selectivity, low extraction efficiencies, and insufficient sensitivity, thus limiting their applicability in studying the complex and diverse active component groups in TCMs. Herein, we proposed a novel micelle-based interface imprinting strategy by integrating multi-template imprinting with mesoporous silica. Specifically, caffeic acid, serving as an epitope template for chlorogenic acid, along with 4-hydroxycinnamic acid, ferulic acid, and cinnamic acid, collectively constituted a multi-template system. Micelles were generated using a cationic surfactant cetyltrimethylammonium bromide, which confined the four template molecules to the micelle surface through electrostatic attraction. Aminopropyltriethoxysilane, 3-ureidopropyltriethoxysilane, and benzyltriethoxysilane were selected as functional monomers, while tetraethyl orthosilicate were selected as both a cross-linker and a silicon source for the synthesis of multi-template imprinted mesoporous silica nanoparticles (MTIMSNs). The MTIMSNs demonstrated high specificity and impressive adsorption capacity for chlorogenic acid, caffeic acid, 4-hydroxycinnamic acid, ferulic acid, and cinnamic acid, with maximum cross-reactivities of 8.8 %, 7.6 %, 6.8 %, 9.5 %, and 11.5 %, respectively, and corresponding adsorption capacities of 3.712, 4.114, 4.843, 3.517, and 2.814 mg/g, respectively. The MTIMSNs-based affinity extraction coupled with high performance liquid chromatography have been successfully applied to the determination of the five cinnamic acid derivatives in Taraxaci Herba .
研究领域:
分析化学
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药学
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材料科学
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产品关联
DOI
PubMed
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2015
·Vol. 26
·期 5
·476-486
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IF 1.757
Pengfei Ma,Wenming Yang,Ting Fan,Hong Liu,Zhiping Zhou,Jinhui Li,Lin Zhang,Wanzhen Xu
Multi-template molecular imprinting technique was employed for the theoretical study about industrial oil denitrification. Prior to the preparation of multi-template molecularly imprinted polymers (MT-MIPs), density functional theory was used for simulating the imprinted pre-assembly systems composed of template (aniline, indole, or 3-methylinndole) and monomer [methacrylic acid, acrylamide (AM), and 4-vinylpyridine]. MT-MIPs were synthesized as surface MIPs simply and successively by seeded emulsion polymerization or two-stage precipitation polymerization. The experimental results were consistent with the simulative results, which demonstrated that AM was more suitable monomer together. In addition, seeded emulsion polymerization synthesized MT-MIPs with better performance compared with two-stage precipitation polymerization. The adsorption kinetics and adsorption isotherm of MT-MIP prepared with AM using seeded emulsion polymerization were fitted with different models. The fitting results indicated that pseudo-second-order kinetics model and Freundlich isotherm model were suitable for describing the adsorption process of AM seeded emulsion polymerization. This study will provide a certain guidance and theoretical basis for introducing the combination of multi-template molecular imprinting technique and computational simulation into the field of industrial denitrification. Copyright © 2015 John Wiley & Sons, Ltd.
研究领域:
环境科学
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化学工程
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计算化学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）