JOURNAL OF CHROMATOGRAPHY A
·
2018
·
IF 3.716
Lei Hou,Fei Feng,Wenbin You,Pengcheng Xu,Fan Luo,Bowen Tian,Haimei Zhou,Xinxin Li
Microfabricated semi-packed gas chromatography (GC) columns coated with two kinds of mesoporous silica (MS) stationary phase have been explored and compared in this paper. The micro GC (μGC) columns are fabricated by microelectromechanical system (MEMS) technique. MSs with pore size of 2 and 5 nm are prepared using two different soft-templates and deposited on the inner surface of the μGC columns by dip-coating. For the first time, the influence of pore size of MS stationary phase on the separation performance in a μGC column has been investigated. As demonstrated, the mixtures of light alkanes (C1–C4) or heavy alkanes (C5–C10) can be well separated in both columns, where the separation resolution is always higher than 1.25 except for C1–C2 and C5–C6. Considering the pore size effect on the separation performance, it is shown that analytes, especially those with bigger size, display longer retention time in the column with larger pore size. For C10, the retention time in 5 nm-MS column is 200% longer than that in 2 nm-MS one.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2023
·
IF 13.3
Yi Zeng,Keliang Liu,Haibo Ding,Zhejun Chong,Yanfang Niu,Yijun Guo,Mengxiao Wei,Xin Du,Zhongze Gu
Photonic crystal hydrogels (PCHs), with smart stimulus-responsive abilities, have been widely exploited as colorimetric sensors for years. However, the current fabrication technologies are mostly applicable to produce PCHs with simple geometries at the sub-millimeter scale, limiting the introduction of structural design into PCH sensors as well as the accompanied advanced applications. This paper reports the microfabrication of three-dimensional (3D) PCHs with the help of supramolecular agarose PCH as a sacrificial scaffold by two-photon lithography (TPL). The supramolecular PCHs, formulated with SiO 2 colloidal nanoparticles and agarose aqueous solutions, show bright structural color and are degradable upon short-time dimethyl sulfoxide treatment. Leveraging the supramolecular PCH as a sacrificial scaffold, PCHs with precise 3D geometries can be fabricated in an economical and efficient way. This work demonstrates the application of such a strategy in the creation of structural-designed PCH mechanical microsensors that have not been explored before.
研究领域:
材料科学
·
生物传感器
·
光学工程
✓ 已验证
DOI
PubMed
高影响因子
Materials
·
2019
·Vol. 12
·期 22
·3710
·
IF 2.972
E Cheng,Ben Xing,Shanshan Li,Chengzhuang Yu,Junwei Li,Chunyang Wei,Cheng Cheng
The microelectrode is an essential and vital part in microsensors that are largely used in industrial, chemical, and biological applications. To obtain desired microelectrodes in great quality, it is also of great necessity and significance to develop a robust method to fabricate the microelectrode pattern. This work developed a four-terminal differential microelectrode that aims at recognizing microparticles in fluids. This microelectrode pair consisted of a high height–width ratio microelectrode array fabricated using a pre-designed microelectrode pattern (a micro-scale channel) and melted liquid metal. The surface treatment of microelectrodes was also investigated to reveal its impacts on the continuality of melting metal and the quality of the fabricated microelectrode patterns. To evaluate the performance of micro-casting fabricated electrodes, a microfluidic device was packaged using a microelectrode layer and a flow layer. Then impedance cytometer experiments were performed using sample fluids with polymer particles in two different sizes in diameter (5 μm and 10 μm). In addition, engine oil was tested on the microelectrodes as complex samples. The number of abrasive particles in the engine oil can be collected from the developed microfluidic device for further analysis.Keywords:microfabrication;melting metal;surface pretreatment;impedance cytometer;differential amplifier;wear particle detection
研究领域:
材料科学
·
生物医学工程
·
微机电系统
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Additive Manufacturing
·
2023
·
IF 11
Ka-Wai Yeung,Zhenjia Huang,Chi-Yeung Mang,Chak-Yin Tang,Wing-Cheung Law,Gary Chi-Pong Tsui,Xin Zhao
This study presents a fabrication strategy for 3D carbon microstructures using via two-photon vat photopolymerization (2p-VPP) and susceptor-assisted microwave pyrolysis (SMWP). Fabricating carbon-based electrode materials with miniaturized functional structures is pivotal for developing high-performance electrochemical microdevices . However, efficiently producing these structures in the submicron regime with desired materials is still challenging. To address this, a hybrid microfabrication strategy was developed, and 3D carbon-based microstructures with submicron resolution were successfully produced. A carbon nanotube nanocomposite photoresist (SCNT-PR1) with improved dispersibility was first prepared. After a comprehensive printability assessment, 3D microstructures with a resolution of 833 ± 54 nm were produced using 2p-VPP. Through SMWP, the microstructures were transformed into pyrolytic carbon (PyC) nanocomposite microstructures with retained geometrical features. SMWP was shown to produce PyC with a less disordered carbon atomic structure, thanks to the accelerated pyrolysis reaction under MW irradiation, when compared to pyrolysis using a conventional furnace. The resistivity was reduced by over 75% from 0.69 ± 0.13 Ω cm to 0.16 ± 0.01 Ω cm, and enhanced electrochemical performance was confirmed. The fabricated PyC nanocomposite showed a further 12% reduction in electrical resistivity and a 20% lower charge transfer resistance for the redox reaction when using SCNT-PR1 as the precursor. Overall, this hybrid fabrication strategy demonstrates the advantages of producing 3D carbon microstructures with precise control over the geometric features and enhancing electrical and electrochemical properties compared to the conventional pyrolysis method. Its potential could be extended to the fabrication of miniaturized electrochemical devices , including microelectronics and point-of-care devices.
研究领域:
材料科学
·
微纳制造
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2017
·
IF 7.504
Shuxin Wei,Jie Liu,Yuanyuan Zhao,Tingbin Zhang,Meiling Zheng,Feng Jin,Xianzi Dong,Jinfeng Xing,Xuanming Duan
The microtechnology of controlling stimuli-responsive biomaterials at micrometer scale is crucial for biomedical applications. Here, we report bovine serum albumin (BSA)-based three-dimensional (3D) microstructures with tunable surface morphology and pH-responsive properties via two-photon polymerization microfabrication technology. The laser processing parameters, including laser power, scanning speed, and layer distance, are optimized for the fabrication of well-defined 3D BSA microstructures. The tunable morphology of BSA microstructures and a wide range of pH response corresponding to the swelling ratio of 1.08–2.71 have been achieved. The swelling behavior of the microstructures can be strongly influenced by the concentration of BSA precursor, which has been illustrated by a reasonable mechanism. A panda face-shaped BSA microrelief with reversible pH-responsive properties is fabricated and exhibits unique “facial expression” variations in pH cycle. We further design a mesh sieve-shaped microstructure as a functional device for promising microparticle separation. The pore sizes of microstructures can be tuned by changing the pH values. Therefore, such protein-based microstructures with controllable morphology and pH-responsive properties have potential applications especially in biomedicine and biosensors.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
·
2022
·Vol. 32
·期 6
·065009
·
IF 2.282
Minjie Zhu,Rui Liu,Hongbo Sang,Xiaohui Du,Shuai Liu,Xinyu Liu,Kemeng Ji,Yanwei Xiong,Xiaojuan Li,Yifang Liu,Lingyun Wang
This paper reports a method for the preparation of glass by reflowing commercial mixed micro and nano powders. High-quality micro-structure glass is formed by a microfabrication process combined with reflow process of the mixed micro and nano powders. The quality of glass prepared by different components was investigated and analyzed. Characterization of the formed glass micro-structure was performed by combining scanning electrical microscopy, energy dispersive spectroscopy, x-ray diffraction, and x-ray photoelectron spectroscopy. The glass reflow results were compared with the anodic bonding sample, which showed micro-structure glass prepared by our method was well-formed with high density and transparency. These results may inspire new possibilities for glass-based microsystems and MEMS applications.
研究领域:
材料科学
·
微制造技术
·
纳米技术
·
光学
✓ 已验证
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2024
·Vol. 171
·期 5
·053507
·
IF 3.1
Wenzheng Wu,Xiaojie Tang,Jing Wang,Chenghan Zhao
With the rapid development of electronics, additive manufacturing of complex three-dimensional microscale metal and alloy structures has emerged as one of the future directions for advanced technologies. In this study, a localized electrochemical deposition technique was developed which enables the fabrication of microscale three-dimensional metal structures in an ambient environment. Notably, we investigated the effects of voltage, initial electrode gap, and electrolyte composition on the deposition of Cu-Ni alloy. Furthermore, we successfully fabricated Cu-Ni equiatomic micro-columns, providing possibilities for the micro/nanoscale fabrication of commercial K-Monel copper. Finally, based on these foundations, we successfully shaped overhanging structures with various angles as well as an "H" structure using a rotating cathode substrate, demonstrating their potential in the fabrication of Cu-Ni alloy micro components.
研究领域:
材料科学
·
电化学
·
微制造
·
增材制造
✓ 已验证
产品关联
DOI
高影响因子
Small Methods
·
2024
·
IF 10.7
Qingxin Guo,Binglin Zeng,Yingnan Cao,Xiaofeng Li,Jingyuan Chen,Wei Wang,Jinyao Tang
Synthetic Janus micro/nanomotors can efficiently convert ambient energy into asymmetrical self-propulsive force, overcoming random thermal fluctuations and enabling autonomous migration. Further modifications to the motors can equip them with different functional modules to meet different needs. However, developing a versatile and high-yield fabrication method for multifunctional Janus micromotors remains challenging. In this study, a modular fabrication approach for micromotors with a particle-tip structure based on the self-focusing lithography induced by an array of TiO 2 microspheres is presented. By adjusting the tip composition or loading, precise programming of motor functionality is achieved, allowing for various capabilities such as photoredox reaction-induced propulsion, fluorescent imaging, electric and magnetic navigation. Furthermore, the flexibility of this fabrication method by selectively loading materials onto two tips is demonstrated to achieve multifunctionality within a micromotor unit. This study proposes a straightforward and versatile approach for modular functional micromotors.
研究领域:
材料科学
·
纳米技术
·
微制造
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2024
·
IF 13
Haoying Wang,Junfeng Xiong,Yuzhen Cai,Wei Fu,Yukun Zhong,Teng Jiang,U Kei Cheang
All-inorganic cesium lead halide (CsPbX 3 , X = Cl, Br, I) perovskite nanocrystals have drawn great interest because of their excellent photophysical properties and potential applications. However, their poor stability in water greatly limited their use in applications that require stable structures. In this work, a facile approach to stabilize CsPbBr 3 nanowires is developed by using SU-8 as a protection medium; thereby creating stable CsPbBr 3 /SU-8 microstructures. Through photolithography and layer-by-layer deposition, CsPbBr 3 /SU-8 is used to fabricate bilayer achiral microswimmers (BAMs), which consist of a top CsPbBr 3 /SU-8 layer and a bottom Fe 3 O 4 magnetic layer. Compared to pure CsPbBr 3 nanowires, the CsPbBr 3 /SU-8 shows long-term structural and fluorescence stability in water against ultrasonication treatment. Due to the magnetic layer, the motion of the microswimmers can be controlled precisely under a rotating magnetic field, allowing them to swim at low Reynolds number and tumble or roll on surfaces. Furthermore, CsPbBr 3 /SU-8 can be used to fabricate various types of planar microstructures with high throughput, high consistency, and fluorescence properties. This work provides a method for the stabilization of CsPbBr 3 and demonstrates the potential to mass fabricate planar microstructures with various shapes, which can be used in different applications such as microrobotics.
研究领域:
材料科学
·
纳米技术
·
微制造
·
光子学
·
机器人技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
·
2024
·Vol. 34
·期 4
·045012
·
IF 2.4
E Cheng,Yeming Zhu,Qibo Deng,Zhengyan Zhang,Xintao Tian
The electrode is an important part of a micro-ultrasonic phased array, commonly fabricated by magnetron sputtering technology. However, with the expansion of the application field, the structures of the phased arrays are becoming more complex, making the traditional magnetron sputtering method no longer applicable, and the realization of micro-scale phased array electrodes by direct printing technology still faces great challenges. Herein, an electric field-driven direct printing method was proposed to fabricate micro-ultrasonic phased array electrodes. The influence of sintering parameters on the resistivity and the effect of printing parameters on the geometric size and surface morphology of the electrode were comprehensively explored, and the mathematical model between the electrode line width and the printing parameters was established. The final printed electrodes exhibit superior properties with a resistivity of 2.4 × 10−7\Omega\cdot m, a surface roughness range of 460–550 nm, and a line width range of 125–480 µm. Additionally, a micro-scale electrode was printed on the piezoelectric ceramic with PZT-5 as the material, and after polarization treatment, the piezoelectric coefficient can reach 405 pC N−1, which proves that this method can be applied in the field of fabricating phased array electrodes.
研究领域:
材料科学
·
超声技术
·
微制造
✓ 已验证
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2023
·
IF 19
Tanyong Wei,Ruizhou Zhao,Lijun Fang,Zongze Li,Ming Yang,Zhen Zhan,U. Kei Cheang,Chengzhi Hu
The bottom-up assembly of premagnetized microgels offers remarkable flexibility in programmability, material selection, and complexity for fabricating programmable magnetic soft machines with discrete 3D magnetization profiles. However, the current microgel bonding encounters challenges due to the utilization of adhesives for attachment, biocompatibility for in vivo applications, and the need for elevated temperature for self-healing materials. Here, an approach is presented that leverages N-hydroxysuccinimide ester-activated sodium alginate (SA-NHS) and chitosan (CS) to form modular gels for on-demand assembly through covalent bonding, yielding a tough and durable interface. Photolithography-based patterning and magnetic maneuverability are imparted by introducing poly(ethylene glycol) diacrylate and ferromagnetic particles into SA-NHS or CS, resulting in the creation of modularized magnetic or nonmagnetic microgels. Different magnetization profiles of the modular microgel can be achieved by magnetizing the ferromagnetic particles inside the microgel. To prove the versatility of the proposed method, several programmable magnetic soft machines are developed for various application scenarios, including heterogeneous cell-laden hydrogel assemblies, multisegmented magnetic soft swimmers, programmable magnetic switches for electric circuits, and magnetically triggered release from drug-encapsulated magnetic capsules. This proposed approach holds great potential to engineer highly intricate and hierarchical architectures, enhancing the functionality, versatility, and adaptability of programmable soft machines.
研究领域:
材料科学
·
生物医学工程
·
软体机器人
·
微制造
✓ 已验证
DOI
高影响因子
Advanced Electronic Materials
·
2025
·Vol. 11
·期 15
·e00192
·
IF 5.3
Yikang Li,Dazhi Wang,Yiwen Feng,Chang Liu,Xu Chen,Zefei Li,Xiangji Chen,Ran Zhang,Xiaopeng Zhang,Shiwen Liang,Liujia Suo,Weiwei Li,Guo Liu,Jifei Liu,Tiesheng Wang
Directional acoustic sensing can be used for localization and detection, has a wide range of applications in various fields, including rescue robotics, drone positioning, and underwater navigation. It is, however, a challenge to sense both the amplitude and direction of the acoustic waves with a simple sensor design. In this paper, a series of artificial cilia is prepared using additive micro-manufacturing technologies for direction-sensitive acoustic sensing, including electrospray and 3D micro-direct ink writing. The response of the artificial cilia at resonance is significantly enhanced, while the resonance frequencies decrease with increasing length, and the response increases due to the amplification. Two resonances are achieved on a cilium by printing two independent electrode-to-electrode interconnect bridges. Two signal channels of the artificial cilia produce an ‘8’-shaped loop by varying acoustic excitation angles, showing that both amplitude ratio and phase difference are direction-dependent. The two voltages of the artificial cilia can be decoupled to produce different frequencies, amplitudes, and phase differences, thus enabling directional detection of multiple sound sources. The direction-sensitive acoustic sensing is achieved by micro-manufacturing artificial cilia. This effort opens an avenue in the fields of cochlear and device detection with promising applications.
研究领域:
声学传感
·
微制造
·
机器人学
·
仿生工程
·
水下导航
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）