Applied Materials Today
·
2025
·
IF 6.9
Jiaxin Li,Yanzhi Xing,Han Leng,Qi Han,Yanfeng Zhang,Jianhua Wang,Xuwei Chen
The combination of photothermal therapy (PTT) and reactive oxygen species (ROS)-involved photodynamic therapy (PDT) holds great promise in enhancing anticancer effect. Herein, a MoS 2 -based multifunctional biomimetic nanotherapeutic platform for synergistic PTT and PDT anti-tumor therapy and real-time self-evaluation of therapeutic effect was developed. MoS 2 hollow nanospheres and fluorescence TAPP-Ma was cloaked with a 4T1 cell-activated fibroblast cell (CM-AF) hybrid membrane to give nanosystem CM-AF-MoS 2 @TAPP-Ma. The hybrid membrane as a delivery system not only offers the nanotherapeutic platform with homotypic targeting ability, but also effectively eliminates the barrier effect of tumor tissue microenvironment. Caspase 3 (Casp3) inside cancer cells activated by the PTT effect of MoS 2 hollow nanospheres broken down TAPP-Ma, triggering the PDT of TAPP. At the same time, the fluoresce “turn-off” of TAPP-Ma provided the base for the self-evaluation of therapeutic effect. The in vitro and in vivo outcomes suggested that the MoS 2 -based multifunctional biomimetic nanotherapeutic platform exhibited synergistic cascade effect for cancer therapy, making it an promising anti-cancer candidate in biomedical clinical application.
研究领域:
生物医学工程
·
肿瘤学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Wenjing Ma,Wenxuan Cao,Tao Lu,Ranhua Xiong,Chaobo Huang
Extensive progress has been made to construct superwetting membranes for oil/water separation. However, the membrane with hierarchical micro/nanostructure fabricated by chemical method generally involves tedious, time-consuming processes and cause secondary pollutants, which has greatly restricted their wide application. We herein report the rational design of a porous hybrid membrane (ZIF-8 @PAN) by water etching of sacrificial polyvinylpyrrolidone (PVP) of blowing-spun polyacrylonitrile (PAN)/PVP composite nanofibrous membrane during the process of in-situ growth of ZIF-8 nanoparticles onto the fiber, for effective separation of on-in-water emulsion and water purification . Specially, the porous structures increase the gaps among the fibers, thus creating new penetration paths. The formed ZIF-8 nanoparticles improved the underwater superoleophobicity and facilitated the emulsion demulsification due to the increment of the roughness of the as-fabricated membrane. Therefore, the ZIF-8 @PAN membrane exhibits high flux (> 4410 L m −2 h −1 ) and separation efficiency (> 99.8%) for various surfactant-stabilized oil/water emulsions (SSEs). Besides, the synergistic effect of the electrostatic adsorption and the ZIF-8 photodegradation also render this membrane with a high organic dye removal efficiency (>90%). Meanwhile, the membrane demonstrates outstanding antibacterial activity. Hence, the synergistic effect of low oil adhesion, photocatalysis , and antibacterial effect contributes to the enhancement anti-fouling ability. Further, the membrane also exhibits good chemical stability and effective separation of complex wastewater. This strategy may shed light on the design of multifunctional membranes for the treatment of complex oily wastewater.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 60
·55272-55281
·
IF 3.289
Chengyun Gao,Minhua Zhang,Fusheng Pan,Lingtao Wang,Jiayou Liao,Teng Nie,Jing Zhao,Keteng Cao,Lei Zhan,Zhongyi Jiang
In this study, hybrid membranes incorporated with sulfonated carbon molecular sieves were fabricated and utilized for pervaporation dehydration of an acetone/water mixture. First, carbon molecular sieves (CMS) were synthesized via a hard template method, and sulfonated by concentrated H2SO4 to prepare sulfonated carbon molecular sieves (SCMS). The pore structure, surface properties and morphological features of CMS and SCMS were examined by XRD, FT-IR, TEM, EDX, nitrogen adsorption–desorption and HRTEM. The results showed that the obtained CMS had an ordered mesoporous structure with cylindrical channels and large surface area. After sulfonation, the surface properties of CMS changed from hydrophobic to hydrophilic. Then, SCMS with different contents were incorporated into a chitosan (CS) matrix to fabricate CS-SCMS hybrid membranes. The incorporation of SCMS can simultaneously create more water transportation pathways due to the ordered mesoporous structure and increase the number of hydrophilic sites due to the sulfonic acid groups within the membranes. When the content of SCMS was 2 wt%, an optimum separation performance with a separation factor of 832 and a permeation flux of 1.81 kg m−2 h−1 was acquired, which was increased by 2 times for the separation factor and 1.67 times for the permeation flux compared with those of the pure CS membrane. Meanwhile, the hybrid membrane showed good long-term stability.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 135
·期 12
·46034
·
IF 1.86
Jiqin Chen,Chunhui Shen,Shanjun Gao,Yuan Yuan,Xuechao Ren
Novel organic–inorganic hybrid membranes, based on poly(2,6-dimethyl-1,4-phenylene oxide), have been prepared through 1,2-dimethylimidazole functional groups and double crosslinking agents including 3-glycidyloxypropyltrimethoxysilane and tetraethyl orthosilicate by sol–gel process for the purpose of improving the conductivity and alkaline resistance. The structure of membranes was characterized using Fourier-transform infrared spectra, 1 H NMR, and X-ray diffraction. The physico-chemical properties of all membranes were shown in ion exchange capacity, water uptake, stability, and conductivity. Membranes with OH – conductivity up to 0.022 at 25 °C and 0.036 S cm −1 at 80 °C. Promisingly, the chemical stability of the resulting membranes remains unchanged after storage in 2 mol dm −3 KOH at 25 °C over at least 10 days. The tensile strength can be higher than 30 MPa, and the elongation at break (Eb) is in the range 6.68–10.84%. Hence, this hybrid membrane can be potentially applied in alkaline fuel cells. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46034.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Bingbing Yang,Lu Bai,Tingting Li,Liyuan Deng,Lei Liu,Shaojuan Zeng,Jiuli Han,Xiangping Zhang
Efficient separation and recovery of ammonia (NH 3 ) is essential for environmental protection and resource utilization. In this work, hybrid membranes for NH 3 separation through multiple-site interaction were developed by combining the unique features of ionic liquids (ILs) and a midblock-sulfonated block copolymer . The functionalized ILs ([2-Mim][NTf 2 ] and [Im][NTf 2 ]) with ammonia interaction sites were incorporated into the Nexar™ matrix, which greatly improves the affinity for NH 3 over nitrogen (N 2 ) and hydrogen (H 2 ). Benefited from the self-assembly of the block copolymer, the hybrid membranes primarily exhibit lamellar morphology. More continuous ionic domains with well-distributed ILs were formed in the hybrid membranes, contributing to forming interconnected channels for enhanced gas transport. In this case, addition of the ILs into the Nexar matrix significantly enhances NH 3 separation performance. Nexar/[Im][NTf 2 ]-25 membrane achieves the highest NH 3 permeability of 3565 Barrer and a maximum NH 3 /N 2 and NH 3 /H 2 ideal selectivity of 1865 and 364, respectively. The significantly enhanced NH 3 permeation compared with the neat Nexar membrane indicates the positive role of ILs in the hybrid membranes.
研究领域:
环境科学
·
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 47
·期 5
·2248-2256
·
IF 3.925
Defeng Hu,Rongzhong Li,Yide Han,Hao Meng,Xia Zhang
Currently, the co-immobilization of multi-enzymes on a solid carrier and their applications in cascade catalytic reactions are primarily studied. In this study, a MOF/polymer porous membrane composed of DUT-5 incorporated polyvinylidene fluoride (PVDF) is constructed and employed in the co-immobilization of porcine pancreatic lipase (PPL) and glucose oxidase (GOx) for the first time. The loading amounts of DUT-5 nanoparticles were varied to optimize the subsequent immobilization efficiency for the two enzymes. The adsorption conditions, isotherms and kinetics for both PPL and GOx were investigated systematically, and the optimum adsorption conditions were determined and used in the co-immobilization of the two enzymes step by step. It is interesting that the maximum adsorption amounts for the two enzymes in the co-immobilization process are similar to the results obtained in the single enzyme immobilization, which indicates the better compatibility of PPL and GOx in the hybrid membranes. The catalytic activities of the co-immobilized enzymes were evaluated using a cascade oxidation reaction, in which H2O2 produced in the GOx-catalyzed oxidation of glucose worked as the oxidant in the subsequent oxidation of styrene. Further, the catalytic efficiency of the co-immobilized enzymes is compared to that of the mixed free PPL and GOx. The improved catalytic rates and better reusability of the co-immobilized enzymes highlight the broader applications of MOF-based membranes in the co-immobilization of two or more enzymes and the catalytic applicabality in the cascade organic reactions.
研究领域:
生物化学
·
材料科学
·
酶工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2020
·
IF 7.183
Zhenguo Zhang,Jiahui Ren,Jingmei Xu,Zhe Wang,Wenwen He,Shuang Wang,Xudong Yang,Xinming Du,Lingxin Meng,Pengyun Zhao
Metal-organic frameworks-based hybrid proton exchange membranes could combine the advantages of organic and inorganic materials with excellent chemical and physical stability and good proton conductivity. In this work, two kinds of functionalized MOFs were synthesized based on MOF-801. Imidazole@MOF-801 was prepared by the impregnation method, which mainly incorporated free imidazole molecules into the pores of the MOF-801. Imidazole-MOF-801 was obtained by in-situ method, which imidazole further acted as non-structural ligands to coordinate to the zirconium metal sites. Furthermore, the hybrid membranes were fabricated with synthesized MOFs as fillers and sulfonated poly (arylene ether ketone sulfone) containing carboxyl groups (C-SPAEKS) as organic matrix. The structures and morphologies of the prepared MOFs and hybrid membranes were characterized by 1 H NMR, XRD , FT-IR and SEM. The PXRD results showed that Im@MOF-801 and Im-MOF-801 exhibited excellent stabilities in both water and acid. The proton conductivities of these hybrid membranes were much higher (0.023–0.066 S cm −1 at 30 °C, 0.050–0.128 S cm −1 at 90 °C) than that of pure C-SPAEKS (0.010S cm −1 at 30 °C, 0.024 S cm −1 at 90 °C). Moreover, C-SPAEKS/Im-MOF-801-4% could maintain a stable proton conductivity for more than 100 h. These results indicate that these hybrid membranes have potential as proton exchange membranes.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 51
·40753-40763
·
IF 3.84
Junfen Sun,Lishun Wu,Fang Hu
Octa vinyl silsesquioxane (OvPOSS) was used to synthesis POSS grafted ethylene glycol (EG) (EG-POSS). EG-POSS was synthesized by a two-step route. OvPOSS was first oxidized to prepare Epoxy-POSS. EG was used to graft Epoxy-POSS to obtain EG-POSS by ring opening reaction of epoxy groups. A polyvinylidene fluoride (PVDF)/EG-POSS hybrid membrane was prepared by a phase separation process. POSS was characterized by FTIR, NMR and TEM. The hybrid membranes were characterized by pure water flux, retention ratio to BSA, contact angle, BSA adsorption capacity, mechanical properties, XRD, SEM and AFM. The hydrophilicity and anitifouling properties of the pure PVDF membrane were improved by incorporating EG-POSS. The pure water flux of the hybrid membrane reached a maximum when 0.5% EG-POSS was added in the casting solution. The addition of EG-POSS had a positive effect on the mechanical properties of the PVDF membrane.
研究领域:
材料科学
·
环境工程
·
化学工程
✓ 已验证
DOI
高影响因子
Chemical Science
·
2023
·Vol. 14
·期 14
·3782-3788
·
IF 8.4
Ruihe Yu,Lin Liu,Liying Yin,Yege Jing,Ning Zhang,Hang Bian,Guangshan Zhu
The growth of porous aromatic frameworks (PAFs) on the surface of polymer brushes is reported for the first time. In contrast to PAFs formed in solution, polymer brushes provide a confined environment for PAF growth, resulting in nanosized and homogeneous spherical PAFs formed amongst the polymer brushes. 4-Bromobenzene functionalities from the polymer brushes are utilized to induce PAF growth by a Yamamoto-type Ullman coupling reaction. The size of PAFs can be tailored from 30 nm to 500 nm by subtly changing the structural parameters: e.g. reaction time, grafting density, and concentration of 4-bromobenzene on the surface. The established strategy is not only applicable to the preparation of PAF-1, but can also be extended to the controlled preparation of PAF-5. In addition, free-standing and flexible PS/PAF-1 hybrid membranes are obtained via dissolving the oxidized layer between the polymer layer and the silicon substrate, which can be transferred to any flat substrate. The obtained PS/PAF-1 membrane is proven to show high efficiency in removing dye from water and is promising for eliminating other foulants, such as microorganisms and trace organics.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Yiling Zheng,Hongli Zhang,Shuwen Yu,Hongwei Zhou,Weixing Chen,Jie Yang
Two-dimensional (2D) MXene-based membranes combine unique atomic thickness, well-arranged interlayer channel, and have received growing attention in molecular/ion separation and transport. The low permeability and instability of MXene-based membranes in water purification enable it difficult to be utilized in practical processing. Here, we present a high water-permeability and long-lived MXene membrane by assembling 2D heterostructured MXene/COF flakes on macroporous polymeric support. The intercalation of COFs into the interlayer of Ti 3 C 2 T x nanosheets not only increases the adjacent interlayer space , but also provides abundant molecular sieving pores, thereby enhancing the permeability of MXene membrane. While being applied in removal of organic dyes, the MXene/COF hybrid membrane exhibits a superior water permeance (up to ∼ 300 L m −2 h −1 bar −1 ), and several satisfactorily rejections for different dyes (98.2% for congo red, 98.7% for chrome black T, 96.4% for methyl blue, and 97.2% for methyl orange) are simultaneously achieved. Additionally, the covalent anchoring of COFs on MXene surface can greatly improve the stability. The reduction of hydrophilicity of MXene surface mitigates water molecular absorption on the fluid channel wall and endow the membrane with well swell tolerance in aqueous environment. Such high performance MXene/COF hybrid membrane is mainly caused by the physical sieving mechanism supported by the repulsive interaction, as well as adsorption capability originating from porous COFs. This work provides an alternative approach for the fabrication of high performance MXene-based membranes used for highly effective dye wastewater treatment , and extends the application of 2D membranes in desalination , pollutant treatments, and resource recovery.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Yao-Shen Guo,Yi-Fang Mi,Feng-Yang Zhao,Yan-Li Ji,Quan-Fu An,Cong-Jie Gao
N-aminoethyl piperazine propane sulfonate (AEPPS) modified multi-walled carbon nanotubes (MWCNTs) (AEPPS-PD@MWCNTs) were prepared by co-deposition of dopamine and AEPPS on MWCNTs surfaces. AEPPS-PD@MWCNTs were mixed with piperazine aqueous solution and polymerized with 1,3,5-benzenetricarboxylic chloride (TMC, dissolved in hexane solution) to prepare negatively charged NF membranes, which were characterized by Fourier Transform Infrared Spectroscopy, X-ray Photoelectron Spectroscopy, Transmission Electron Microscopy and Atomic Force Microscopy. It was found that compatibility between AEPPS-PD@MWCNTs and polyamide matrix was enhanced as a result of the multiple interactions between AEPPS-PD@MWCNTs and TMC monomers. At optimized conditions, pure water permeability of hybrid membrane was 127.3 L m −2 h −1 MPa −1 , 1.8 times as high as pristine PIP/TMC membrane without compromising Na 2 SO 4 rejection. Meanwhile, NaCl rejection of hybrid membrane was 19.0%, much lower than pristine PIP/TMC membrane. Hybrid membrane exhibited applications in separation of monovalent/divalent salts and monovalent salts/neutral organics coupled with good stability and better anti-fouling property which was sought for applications in the field of desalination, food and biological separation processes.
研究领域:
材料科学
·
环境工程
·
膜技术
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Xuesong Zhao,Yingying You,Yiyang Ma,Chenchen Meng,Zhenghua Zhang
Toxic organic dyes are a serious threat to the global environment, and membranes with catalytic properties show great promise as a green water treatment method for removing these pollutants. Herein, Ti 3 C 2 /W 18 O 49 photocatalytic membranes were constructed by vacuum filtrating Ti 3 C 2 and W 18 O 49 to form a hybrid layer on a mixed cellulose ester (MCE) support. The efficient separation of dyes was attributed to the negative charge and abundant –OH groups of Ti 3 C 2 /W 18 O 49 , which can capture cationic dyes by electrostatic adsorption and form hydrogen bonds with the amino groups of dye molecules. Moreover, the Ti 3 C 2 /W 18 O 49 membrane exhibited excellent photocatalytic performance and a dye-contaminated membrane was regenerated under visible light in 120 min. The two component materials complement each other, with the W 18 O 49 providing adsorption sites and photocatalytic ability and the Ti 3 C 2 serving as an electron trap and improving charge separation. Photoinduced electrons in the conduction band of W 18 O 49 are transferred to Ti 3 C 2 to form O 2 – , while holes remain in the valence band of W 18 O 49 to generate OH, and h + . O 2 – and OH are mainly responsible for the degradation of dyes. Therefore, this efficient and easily prepared membrane shows practical potential as a next-generation method for dye removal from water.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）