Plants-Basel
·
2026
·Vol. 15
·期 16
·2500
·
IF 4.7
Su Yan,Yinghui Gu,Yifei Kong,Yudi Xiang,Bohan Yang,Xiaomeng Su,Li Sheng,Kai Song
Aronia melanocarpacontains abundant phenolic compounds, including procyanidins, flavonols, flavan-3-ols, and phenolic acids, but its pronounced astringency limits its broader use in food applications. Catechol and other oxygen-donor motifs in plant phenolics are known to associate with Fe3+and can support metal–phenolic assembly. In this study, ultrasound-assisted cellulase–pectinase extraction was used to recover anA. melanocarpapolyphenol extract, which was subsequently combined with Fe3+to construct a plant-derived hair dye coating on keratin fibers. Under optimized extraction conditions, the total phenolic yield reached 82.315 mg gallic acid equivalents (GAE)/g dry fruit. A limited targeted LC–MS/MS panel was used to evaluate 12 selected non-anthocyanin phenolic analytes, including procyanidin dimers, a flavan-3-ol, flavonols, and phenolic acids; the contribution of the pH-sensitive anthocyanin fraction was not resolved. Among the tested metal ions, Fe3+produced the strongest chromogenic response. The optimized L-cysteine pretreatment–Fe3+mordanting–polyphenol dyeing sequence produced a ΔE* of 55.42. Adsorption experiments empirically described the uptake behavior of the polyphenol extract, whereas complementary surface, spectroscopic, elemental, diffraction, thermal, and wettability analyses were consistent with the presence of a relatively uniform Fe-containing polyphenol coating at the hair fiber interface. Neither the adsorption-model fits nor the individual characterization techniques uniquely resolved the underlying molecular mechanism. Preliminary HET-CAM, single-exposure dermal, and acute eye irritation assessments showed no obvious acute irritation under the tested conditions. An exploratory image-based analysis examined whether standardized hair tress photographs could approximate a predefined colorimetric score. Because only 30 independent original samples were available and no external validation was performed, this analysis was treated solely as a proof of concept. This laboratory proof-of-concept extends established Fe3+–polyphenol assembly chemistry to a compositionally complexA. melanocarpaextract for hair fiber coloration. Further work is required to clarify anthocyanin behavior, simplify the sequential protocol, and benchmark its performance against representative commercial hair dyes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Hang Jia,Shiqi Fan,Rui Cai,Zhouli Wang,Yahong Yuan,Tianli Yue
The abuse of conventional antibiotic is considered to be one of the main factors hindering the healing of bacteria-infected wound, which has severely threatened the public health. Reactive oxygen species (ROS), such as the common commercial H 2 O 2 have been used as a healing strategy to combat wound infection. However, the low efficiency limits its application. Herein, a litchi-like glucose oxidase-integrated magnetic metal-organic framework (pFe 3 O 4 @MOF-GOx) with satisfactory biocompatibility has been constructed as glucose-triggered cascade reagent for antibacterial application. The immobilized glucose oxidase (GOx) can catalyze the decomposition of non-toxic glucose into H 2 O 2 and gluconic acid. Subsequently, the generated H 2 O 2 is catalyzed by the intrinsic peroxidase-like of pFe 3 O 4 @MOF to produce toxic hydroxyl radicals . In vitro antibacterial investigations demonstrate the synthesized hybrids display broad-spectrum antibacterial performance with the presence of glucose. Meanwhile, external H 2 O 2 is not required in this developed strategy, which avoids the undesired damage to normal tissues caused by the H 2 O 2 with relatively high concentration in peroxidase-like system. Altogether, the construction of glucose-triggered cascade strategy with effective antibacterial activity provides an alternative method for the treatment of bacterial infected wound.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Hang Jia,Shiqi Fan,Rui Cai,Zhouli Wang,Yahong Yuan,Tianli Yue
The abuse of antibiotics seriously threatens the public health, which leads to the urgent need to develop novel antimicrobial strategies. Reactive oxygen species (ROS) have been considered as an alternative approach for bacterial inactivation. At present, magnetic materials, especially iron oxide (Fe 3 O 4 ) nanoparticles have gained widely application in biomedical field. Owing to the intrinsic peroxidase-like activity, Fe 3 O 4 can catalyze the decomposition of hydrogen peroxide (H 2 O 2 ) to generate hydroxyl radical (⋅OH) under acidic conditions. Recently, Fe 3 O 4 -based peroxidase mimics have been developed for wound infection therapy. However, the direct introduction of H 2 O 2 with relative high concentration may induce undesired effect to normal tissues, and the infection site with near neutral pH still limits the antibacterial efficiency. Herein, carboxyl modified Fe 3 O 4 immobilized silver nanoparticles (Ag NPs) and glucose oxidase (GOx) were synthesized as a self-activated cascade regent. GOx endowed the hybrids with catalytic activity, which could convert glucose into gluconic acid, which activated the peroxidase-like activity of Fe 3 O 4 by decreasing the pH value. Moreover, the self-supplied H 2 O 2 was subsequently catalyzed by Fe 3 O 4 to generate ⋅OH. By combining the excellent antimicrobial performance of Ag NPs, the enzyme assisted magnetic hybrids exhibited robust antibacterial activity, which exhibited a great potential in bacteria-infected wound therapy.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2022
·
IF 5.895
Hang Jia,Xuejun Zeng,Rui Cai,Zhouli Wang,Yahong Yuan,Tianli Yue
The risk of fruit juice contamination caused by microorganisms, especially Alicyclobacillus acidoterrestris, has been reported worldwide. To develop cost-effective control methods, in this work, flower-like magnetic molybdenum disulfide (Fe3O4@MoS2) nanoparticles (NPs) were fabricated by a facile two-step hydrothermal method. After further modifying polyacrylic acid (PAA) on the surface of the NPs, epsilon-polylysine (EPL) was immobilized via N-(3-dimethylaminopropyl)-N-carbodiimide hydrochloride/N-hydroxysuccinimide coupling reaction to obtain the Fe3O4@MoS2@PAA–EPL nanocomposites. Antibacterial results exhibited that the synthesized nanocomposites showed effective antibacterial activity against A. acidoterrestris with a minimum inhibitory concentration of 0.31 mg mL–1. Investigation on the antibacterial mechanism revealed that the presence of nanocomposites caused damage and disruption of the bacterial membrane through dent formation, resulting in the leakage of intracellular protein. Moreover, the activity of dehydrogenase enzymes was inhibited with the treatment of Fe3O4@MoS2@PAA–EPL, causing the reduction of metabolic activity and adenosine triphosphate levels in bacteria. Simultaneously, the presence of nanocomposites improved intracellular reactive oxygen species levels, and this disrupted the antioxidant defense system and caused oxidative damage to bacteria. Furthermore, Fe3O4@MoS2@PAA–EPL nanocomposites were confirmed to possess satisfactory biocompatibility by performing in vitro cytotoxicity and in vivo acute toxicity experiments. The aim of this research was to develop a new pathway for the inhibition of A. acidoterrestris in the juice industry.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Anlin Xu,Donghong Wu,Ren Zhang,Siyan Fan,Albert T. Lebedev,Yongjun Zhang
Metal oxides can effectively activate peroxymonosulfate (PMS) to degrade organic contaminants but are usually synthesized via chemical/physical processes involving extreme conditions and hazardous materials. In this study, an innovative bio-synthesis method with a strain of manganese oxidizing bacteria Pseudomonas sp. was developed to prepare multiple metal oxides consisting of iron, manganese, and cobalt (Bio-FeMnCoO x ) for degrading moxifloxacin (MOX) with PMS. It was found that the cultivation time, the dosage of Co, the polishing method are the key parameters regulating the PMS activation performance of Bio-FeMnCoO x . Under the optimal preparing conditions, the MOX degradation kinetic constant of obtained Bio-FeMnCoO x was 7 times that of the chemically synthesized peer. Analysis with XRD, EPS and SEM with EDS mapping showed an amorphous structure of Bio-FeMnCoO x with well distributed Fe, Mn, and Co. Radical quenching and EPR spin-trapping tests demonstrated that SO 4 •- and 1 O 2 were the main reactive oxygen species. The transformation products of MOX were identified by UPLC-QTOF-MS/MS and the possible degradation pathways were accordingly proposed. The respiratory test showed that the toxicity of MOX was reduced by approximately 69% after the degradation with PMS activated by Bio-FeMnCoO x . The study demonstrates the potential of biogenic metal oxides for efficiently activating PMS.
✓ 已验证
产品关联
DOI
高影响因子
Reaction Kinetics Mechanisms and Catalysis
·
2022
·Vol. 135
·期 5
·2457-2473
·
IF 1.843
Huang Jielang,Zhu Zongbo,Zhang Dandan,Li Xiaoguo,Hou Zhanggui,Zhang Yi
A series of iron supported carbon foam catalysts (10Fe/CF) were successfully synthesized via a facile method by impregnation to reveal the influence of a superior diffusion performance on the Fischer–Tropsch synthesis (FTS) reaction. Meanwhile, different amounts of potassium (0–1.5 wt%) were investigated on 10Fe/CF catalyst by the fixed-bed reactor and typical FTS reaction conditions (300 °C, 1.0 MPa). Various characterizations, including XRD, XPS, Raman, SEM etc. were combined to study the structure, texture, diffusion and Fe phase state. The results revealed that 10Fe/CF catalysts showed superior surface area and FTS performance after the addition of K promoter. Significantly, the addition of K facilitated the formation of C-poor iron carbides, contributing to enrich the reactivity for the syngas to light olefins.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2022
·
IF 6.51
Linyi Xu,Rou Guan,Bohong Yu,Yicheng Li,Hongzhuo Liu,Yiguo Jiang
Although deferoxamine (DFO) has been approved for the treatment the iron overloaded diseases, its clinical application is impeded by very short circulation time and its relating toxicity. In this work, the fluorene methoxycarbonyl (FMOC) for “albumin hitchhiking” was used to prolong the plasma circulation time of DFO and reduce toxicity. The designed FMOC-PEG-DFO conjugates were found to reversible bind to albumin and gradually release DFO in vivo . Herein, the FMOC-PEG 1000 -DFO conjugates could increase 30 times the blood circulation time of DFO with the improvement of the iron elimination efficacy. Meanwhile, the conjugates markedly reduced the cytotoxicity of DFO. Taken together, the result demonstrated the FMOC-PEG 1000 -DFO conjugates could be a potential therapeutic choice for iron-overload-related diseases.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2022
·
IF 24.319
Anlin Xu,Siyan Fan,Tong Meng,Ren Zhang,Yunhai Zhang,Shunlong Pan,Yongjun Zhang
Metal oxides, as a popular group of ozonation catalyst, are usually synthesized with physiochemical protocols involving hazardous materials and extreme conditions. In this study, a biological method was studied with manganese oxidizing bacteria Pseudomonas sp. to synthesize multi-metal oxides consisting of iron, manganese, and cobalt (Bio-FeMnCoOx) to catalyze ozonation for the first time. It was found that the dosage of cobalt, the cultivation time, and the polishing methods could significantly impact the catalytic activities of degrading benzotriazole as a model. The second-order degrading kinetic constant with optimized Bio-FeMnCoOx was 4.8 times that with the physiochemically synthesized peer. The activity of Bio-FeMnCoOx was compared with other reported catalysts in terms of Rct value. The quenching tests and EPR spectra indicated the participation of hydroxyl radicals, superoxide radicals, and singlet oxygen. The study demonstrates the great potential of biosynthesis as a green protocol for preparing metal oxides to efficiently catalyze ozonation.
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Oncology
·
2021
·
IF 6.244
Yuan Yin,Ni Shuo,Zhuge Aoxiang,Li Bo,Li Lanjuan
Iron promotes the proliferation of cancer cells, but it also contributes to cell death. Here we explored whether iron could promote the Warburg effect of colorectal cancer (CRC) cells and suppress sensitivity to ferroptosis by inducing reactive oxygen species (ROS) and regulating nuclear factor erythroid 2-related factor 2 (NRF2). In this study, cell proliferation abilities were measured by CCK-8, EdU incorporation, and colony formation assays. Seahorse XF96 respirometry assays were used to detect the Warburg effect and the level of ROS was assess by DCFH-DA fluorescent probes. Results showed that iron exposure promoted the Warburg effect of CRC cells by inducing ROS and activating NRF2 both in vivo and in vitro. In addition, iron exposure also induced ferroptosis in CRC cells, but at the same time its inhibitory proteins SLC7A11 and GPX4 were also upregulated, indicating an enhanced resistance to ferroptosis. Our results revealed that iron can effectively promote tumorigenesis. Meanwhile, iron elimination or a low-iron diet might be valid therapeutic approaches for CRC.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials
·
2021
·Vol. 14
·期 13
·3619
·
IF 3.623
Xiang Zhao,Mu Zhang,Wei Pan,Rui Yang,Xudong Sun
Rational design and economic fabrication are essential to develop carbonic electrode materials with optimized porosity for high-performance supercapacitors. Herein, nitrogen-doped hollow carbon nanospheres (NHCSs) derived from resorcinol and formaldehyde resin are successfully prepared via a self-template strategy. The porosity and heteroatoms in the carbon shell can be adjusted by purposefully introducing various dosages of ammonium ferric citrate (AFC). Under the optimum AFC dosage (30 mg), the as-prepared NHCS-30 possesses hierarchical architecture, high specific surface area up to 1987 m2·g−1, an ultrahigh mesopore proportion of 98%, and moderate contents of heteroatoms, and these features endow it with a high specific capacitance of 206.5 F·g−1at 0.2 A·g−1, with a good rate capability of 125 F·g−1at 20 A·g−1as well as outstanding electrochemical stability after 5000 cycles in a 6 M KOH electrolyte. Furthermore, the assembled NHCS-30 based symmetric supercapacitor delivers an energy density of 14.1 W·h·kg−1at a power density of 200 W·kg−1in a 6 M KOH electrolyte. This work provides not only an appealing model to study the effect of structural and component change on capacitance, but also general guidance to expand functionality electrode materials by the self-template method.Keywords:self-template;hollow structure;multidirectional porosity;nitrogen-doped carbon;supercapacitors
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Yutong Han,Jingjing Zheng,Chao Jiang,Fan Zhang,Lecheng Wei,Liang Zhu
The unceasing algae blooms have led to the deterioration of water quality and ecological imbalance in the entire globe, it’s urgent to investigate its treatment and resource utilization technology . In this study, treated algae was prepared to produce the biochar and then it was utilized as a coagulant for the removal of Microcystis aeruginosa . To improve the pore structure of algae-derived biochar for improving the removal capacity of M. aeruginosa , hydrochloric acid (HCl) modification was applied and optimized by Box-Behnken model-based response surface methodology . After modification by HCl, the specific surface area, pore volume, and average pore diameter of modified algae-derived biochar (MAB) increased to 38.34 m 2 /g, 0.073 cm³ /g, and 7.42 nm, respectively. The removal efficiency of Microcystis aeruginosa (The initial cell density: 4 ×10 6 cells/mL) by the MAB reached 99.02% ± 0.18 under the optimum condition obtained with response surface experiment (dosage of 287.46 mg/L, pH of 8.2, stirring rate of 175 rpm, and stirring time of 6.4 min). At the same time, the removal efficiencies of Chl a, turbidity and total phosphorus of polluted waters reached more than 84%, 91% and 60%, respectively. The dissolved organic matters were removed synchronously, thereby reducing the disinfection by-products formation potential. Electrostatic adsorption has been determined as the predominant force during the coagulation process. In conclusion, the HCl has been proved to be an effective strategy to improve the pore structure and algal removal capacity of MAB, and the MAB could be applied as the suitable materials for the algal coagulation with the advantage of resource utilization.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Xuefeng Wu,Jinyuan Zhu,Waseem Hayat,Yongqing Zhang,Shaobin Huang,Ran Jiang
An iron (Fe)-modified carbon dots (CDs) doped ZIF-8 zeolite imidazole metal-organic frame pyrolyzed composite (5Fe@NC) was prepared and then evaluated as a peroxydisulfate (PDS) activator for the oxidative removal of organic pollutants . The 5Fe@NC/PDS system not only has a good recovery performance, wide pH adaptability, and low activation energy, but also is resistant to environmental interference. The quenching experiments, electron paramagnetic resonance (EPR) detection, and electrochemical analysis all revealed that unlike the widely reported singlet oxygen ( 1 O 2 ) dominated nonradical mechanism, an electron transfer process (ETP) involving a surface bound PDS complex played the main role in pollutants’ degradation by 5Fe@NC/PDS system. The FeN x , defect, graphitic N and hydroxyl group (-OH) acting as active sites, prompted the 5Fe@NC-PDS complex to capture electrons (e − ) from acetaminophen (ACT). This study provides a new approach for xFe@NCs rational design, and deepen the understanding of FeN x activation mechanism of PDS in carbon nanomaterials .
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）