Journal of Inorganic and Organometallic Polymers and Materials
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2019
·Vol. 29
·期 6
·2124-2132
·
IF 1.637
Wang Zirui,Wang Xinyu,Li Jingfang,Li Weizuo,Li Guangming
In this work, a facile and fast luminescence sensing platform for the ratiometric detection of hydrogen sulfide (H 2 S/HS − ) has been constructed by encapsulating the Eu 3+ /β-diketone chromophore into the host framework of MIL-140 (Eu 3+ /TFA@MIL-140C, TFA = 1,1,1-Trifluoro-2,4-pentanedione). It is well known that the energy transfer from the host framework or/and TFA to the Eu 3+ ions can be disturbed easily by some metal ions, such as Cu 2+ ions. Therefore, the ratiometric sensor was constituted with the Eu 3+ /β-diketone moiety as the response signal and the host framework moiety as the reference signal. Furthermore, on the basis of the hard–soft acid–base theory, the Cu 2+ ions could be rapidly caught by HS − , profiting from the low solubility of CuS, realizing the real-time detection by luminescence color change. This sensor shows remarkable property on the detection of H 2 S (HS − in water solution) with low limit of detection (LOD = 7.43 μM) and short response time (< 0.5 min). The good linearity between luminescent intensity and concentration makes the luminescent ratio meter feasible.
研究领域:
材料科学
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分析化学
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环境科学
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DOI
高影响因子
MICROPOROUS AND MESOPOROUS MATERIALS
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2022
·
IF 5.876
Ning Wu,Hao Guo,Liping Peng,Yuan Chen,Lei Sun,Yinsheng Liu,Xiaoqing Wei,Wu Yang
Creatinine (Cre) measurement in biological fluids is an increasingly important clinical measure for evaluating renal insufficiency, thyroid dysfunction, and muscle injury. Therefore, a simple, fast, and reliable Cre analysis method is of great significance to human health. Herein, a novel ratiometric fluorescence sensor, Ag-Eu-MOF-808-EDTA, was synthesized by introducing ethylenediaminetetraacetic acid (EDTA), Ag + , and Eu 3+ into the framework of MOF-808 through three steps of post-synthesis modification, and was used to detect Cre in PBS buffer of pH 7.2 at 35 °C with a “turn-on” ratio response in the presence of various interfering ions and several biomolecules. In this strategy, the characteristic emission of Eu 3+ at 551 nm can be turned on due to coordination between Cre and Ag + , while emission at 613 nm is independent of Cre, which produces a significant ratio response change throughout the cycle. Experimental results showed that the ratio fluorescence sensor displayed a wide linear range for Cre from 0.5 to 350 μM with a low detection limit of 0.42 μM. Finally, a good recovery rate (96.7–102.9%) and appropriate relative standard deviation (RSD <2.39%, n = 3) were obtained during the determination of creatinine in real urine and serum. This work provides additional insights into the detection of creatinine in clinical blood samples.
研究领域:
分析化学
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生物医学
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高影响因子
BIOSENSORS & BIOELECTRONICS
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2024
·
IF 10.7
Chuanyu Yang,Caiyi Du,Feiyu Yuan,Peitong Yu,Boxu Wang,Changshun Su,Ruiqi Zou,Junyang Wang,Xu Yan,Chunyan Sun,Hongxia Li
Benefiting from specific target recognition and trans-cleavage capabilities, the CRISPR/Cas12a system has great application prospects in the design of highly sensitive and rapid fluorescence biosensors. The CRISPR/Cas12a-based fluorophore-quencher molecular beacons exhibit single-color emission and are easily exposed to interference from environmental factors. Herein, we design a CRISPR/Cas12a-derived ratiometric fluorescence sensor for Pb 2+ detection based on embedded carbon dots@zeolitic imidazolate framework-8 (CDs@ZIF-8) composites and DNAzyme. The functions of ZIF-8 about encapsulating red emissive CDs in the inner cavity and adsorbing DNA on the outer surface are integrated to establish dual fluorescence signals, thereby reducing the possibility of interference and improving sensing accuracy. The presence of Pb 2+ is converted into the change of activator by the GR5 DNAzyme to activate the CRISPR/Cas12a system, which provides signal amplification through multiple turnovers of side branch cutting, achieving highly sensitive detection of Pb 2+ with a low detection limit of 18 pM. This method has the advantages of simplicity, universality, and excellent quantitative ability, and has broad prospects in sensing applications.
研究领域:
生物传感
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分子生物学
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环境科学
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DOI
PubMed
高影响因子
JOURNAL OF FLUORESCENCE
·
2025
·
IF 3.1
Han Bo-Ming,Zhang Hao-Rui,Gao Wen-Jie,He Xi-Wen,Li Wen-You,Zhang Yu-Kui
In this work, a dual-emission material based on lanthanide metals was synthesized and used as a ratio fluorescence sensor to respond to Hg 2+ and H 2 O 2 , respectively. Tb-BDC-NH 2 as a bimetal MOFs had double ligands and exhibited double fluorescence emission peaks at 550 nm and 450 nm. The two emission peaks of Tb-BDC-NH 2 can be quenched by Hg 2+ and H 2 O 2 respectively, forming a built-in calibration signal for ratio fluorescence detection. Based on the different detection conditions of the Hg 2+ and H 2 O 2 , the simultaneous detection of the two detection substances can be achieved with simple operation. This detection system had good stability and anti-interference ability. Under optimal conditions, the detection limit for Hg 2+ detection was 0.2 µM. Meanwhile, for the detection of H 2 O 2 , the detection limit was 11 µM and large linear ranges were obtained. Through actual sample testing, it had been proven that the ratio fluorescence sensor based on Tb-BDC-NH 2 had good application prospects. And the work also provided a new idea for double substances detection.
研究领域:
分析化学
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环境科学
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材料科学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
·
IF 4.3
Yulin Zhu,Mengqi Zhu,Qiuju Zhou,Qunwei Shu,Kejun Tan
Up/down-conversion dual-emission carbon dots (U/D-CDs) are rare and have potential in analytical sensing. Herein, a kind of novel U/D-CDs was prepared successfully by a one-step solvothermal method. The prepared U/D-CDs exhibited similar dual-emission behaviors at excitation wavelengths of 300 nm and 680 nm, respectively. In addition, U/D-CDs displayed good photostability and salt-resistance. Due to the protonation-deprotonation, U/D-CDs showed strong pH dependence in the pH range of 2.0–8.0, which developed an up/down-conversion dual-channel ratiometric fluorescence (FL) probe of pH. The FL intensity of U/D-CDs can be effectively quenched by Cu 2+ through the static quenching effect. Meanwhile, an obvious color change from yellow-green to blue can be observed under ultraviolet light with the increase of Cu 2+ concentration. The up/down-conversion dual-channel ratiometric fluorescence sensor can be used for the visual sensing of pH and Cu 2+ , which also eliminates background signals and improves its accuracy and selectivity in complex samples.
研究领域:
分析化学
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材料科学
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环境科学
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DOI
PubMed
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2019
·
IF 3.571
Yong Han,Weixia Yang,Xueli Luo,Xie He,Ying Yu,Chunhua Li,Wenzhi Tang,Tianli Yue,Zhonghong Li
Copper ion (Cu2+)-triggered carbon dots (CDs/Cu) with dual emissions were utilized to develop a ratiometric fluorescence sensor for ultrasensitive detection of inert thiophanate-methyl (TM). TM could be recognized by CDs/Cu through π–π stacking and could chelate Cu2+ of CDs/Cu through metal ion coordination, inducing synchronous fluoresent quenching of the dual emission of CDs/Cu based on the excited state intramolecular proton transfer and the ligand-to-metal charge transfer. The fluorescence ratio of CDs/Cu (F416/F481) linearly responded in a TM concentration of 0.10–20.00 μmol/L with an ultralow limit of detection of 2.90 × 10–6 μmol/L. A synchronous response of the ratiometric sensor enhanced the specificity toward TM and presented remarkable capability of anti-interference in complex matrices. The sensor exhibited satifactory accuracy and precision for practical applications with recoveries of 88.33–101.09% and relative standard deviations of 1.61–5.06%, demonstrating an ultrasensitive ratiometric fluorescent nanosensor for detecting pesticides residues in complex matrices.
研究领域:
分析化学
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环境科学
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食品安全
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产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
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2021
·
IF 4.889
Gengli Huang,Xueli Luo,Xie He,Yong Han,Haiping Zhao,Wenzhi Tang,Tianli Yue,Zhonghong Li
Herein, carbon dots with intrinsic dual-emission fluorescence (d-CDs) at 360 nm (F 360 ) and 530 nm (F 530 ) under excitation of 320 nm were prepared by microwave-assisted heat treatment of o -phenylenediamine (OPD). Cu 2+ could be effectively captured by the d-CDs via coordinating with the nitrogen lone pair of –NH 2 to form a complex (Cu 2+ -OPD) by electron pair sharing. The complex can efficiently quench the fluorescence of F 360 by through-bond energy transfer (TBET) and meanwhile selectively enhance the fluorescence of F 530 by inhibiting the occurrence of photoinduced electron transfer (PET). The unique opposite response of the d-CDs toward Cu 2+ could produce a large change to the value of F 360 /F 530 and thus the d-CDs were utilized to fabricate a ratiometric fluorescent sensor to detect Cu 2+ with a wide linear range of 0.8–55.0 μmol L −1 and a low limit of detection (LOD) of 44.63 nmol L −1 (R 2 = 0.9989). Recoveries of 95.8–102.3% with relative standard deviations (RSD) < 6.7% were achieved in spiked food samples. Moreover, this sensor possessed excellent selectivity and sensitivity for the quantitative determination of Cu 2+ , indicating its promising potentials for constructing a reliable and convenient approach for quick pre-warning of Cu 2+ .
研究领域:
分析化学
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材料科学
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DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2021
·
IF 4.539
Min Yang,Enzhou Liu,Xiaoyun Hu,Hong Hao,Jun Fan
The design of novel Cu 2+ quantitative sensors with highly sensitivity and selectivity is a hot topic of modern chemistry . Herein, a novel ratiometric fluorescence (PL) sensor based on the red-emitting CdTeS quantum dots (QDs) and blue-emitting polyethyleneimine-functionalized carbon dots (PEI-CDs) was firstly designed for sensing Cu 2+ . In the presence of Cu 2+ , a good linear relationship between the ratios (F 520 /F 690 ) of the two peak intensities and the concentrations of Cu 2+ was observed in the range of 0.01–250 µM with the correlation coefficient (R 2 ) of 0.993 and the detection limit as low as 8.07 nM. The ratiometric nanosensor was also used to successfully determine Cu 2+ in plasma samples with satisfactory results obtained. Therefore, we hold the opinion that the developed ratiometric fluorescent sensor based on CdTeS QDs/PEI-CDs will provide technical support for the point-of-caretesting of Cu 2+ .
研究领域:
分析化学
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材料科学
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产品关联
DOI
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2020
·Vol. 104
·期 2
·886-895
·
IF 3.502
Xiaoping Guo,Qiwen Pan,Xiaoqian Song,Qianyi Guo,Shangxiong Zhou,Jianrong Qiu,Guoping Dong
Fluorescent detection is a new spectroscopic measurement for ions sensing due to the advantages of real-time determination with high selectivity, accuracy, and low cost. However, chemosensors based on fluorescent detection are usually determined by absolute intensity from a monochromatic emission signal, which is easy to be fluctuated by the external environment, especially for Fe 3+ detection in complex fluids. Herein, we rationally design a dual-emission Eu 3+ : CDs@ZIF-8 to construct a ratiometric fluorescent sensor with self-calibrating ability for Fe 3+ determination. High efficient carbon dots (CDs) are embedded in europium ions (Eu 3+ )-doped MOF by simple stirring preparation at room temperature. The label-free ratiometric fluorescent probe (I CDs@ZIF-8 /I Eu ) exhibits simultaneous blue and red emission under the same excitation at 365 nm. Remarkably, Eu 3+ : CDs@ZIF-8 displays the superiority of high selectivity to Fe 3+ , which shows ratiometric fluorescence characteristics (I 0 /I) in a range of 0-6 μmol\L with a low limit of detection (LOD) of 0.897 μmol\L. Besides, the CDs-MOF nanocomposite holds good aqueous dispersibility and low cytotoxicity, which shows great potential applications in medical aid including biological detection and clinical diagnosis.
研究领域:
分析化学
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材料科学
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生物医学工程
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Yunsu Ma,Yuan Wang,Yongjie Liu,Lujia Shi,Dongzhi Yang
For this study, a cascade-triggered ratiometric fluorescent sensor based on nanocomposites was designed to detect lactate. This sensor was established by breaking the inner-filter effect (IFE) between blue emission carbon dots (bCDs) and silver nanoparticles (AgNPs) and activating the dynamic quenching process of red emission quantum dots (rQDs) and Ag + . In this sensor (bCDs/AgNPs-rQDs), the fluorescence of bCDs was quenched by the formation of CDs/AgNPs, and recovered by adding lactate. Subsequently, the quenching of rQDs was triggered by Ag + , which originated from the disintegration of AgNPs. This cascade-triggered ratiometric fluorescent sensor for lactate detection was established with the LOD (limit of detection) of 0.12 μM. The developed probe was applied to lactate detection in human serum with satisfactory results, indicating that the probe has enormous potential in clinical practice.
研究领域:
生物传感
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纳米医学
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分析化学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2020
·
IF 6.306
Xie He,Yong Han,Xueli Luo,Weixia Yang,Chunhua Li,Wenzhi Tang,Tianli Yue,Zhonghong Li
A ratiometric fluorescence (FL) sensor was fabricated by coordinating 2, 6-pyridinedicarboxylic acid (DPA) sensitized Tb 3+ (Tb-DPA) with NH 2 and COOH on the surface of the N -doped carbon dots ( N -CDs) for detecting Hg 2+ in seafood. The sensor exhibited two FL emissions at 436 nm ( N -CDs) as the response signal and at 543 nm (Tb-DPA) as the reference signal when excited at 290 nm. After adding Hg 2+ , the FL emission at 436 nm was significantly quenched and the FL emission at 543 nm was negligibly changed. The electron transfer (ET) between COO − of N -CDs and Hg 2+ led to the FL quenching of N -CDs. The FL ratio (F 436 /F 543 ) exhibited a good linear relationship in the Hg 2+ concentrations of 1 161.51 μM with a low limit of detection (LOD) of ~37 nM. The sensor presented high selectivity, satisfactory accuracy and precision toward Hg 2+ in seafood with recoveries of 86.45–114.47% and RSDs of 0.20–1.92%.
研究领域:
分析化学
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环境科学
·
食品科学
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
·
2023
·
IF 2.6
Junfang Chang,Jie Mao,Yifei Lu,Yalei Liu,Sui Wang
Water-soluble purple fluorescent carbon nanodots (P-CDs) were synthesised using 2-phenylphenol, and red fluorescent carbon dots (R-CDs) were prepared from o-phenylenediamine and phosphoric acid. Based on the fluorescence quenching effect of Ag+ on carbon quantum dots, and additionally introducing a red light-emitting quantum dot with excellent performance and high quantum yield, a dual emission ratiometric fluorescent nanosensor (P-CDs/R-CDs) was established. The semi-quantitative detection of silver ions can be realised. Under the excitation light of 254 nm and 365 nm, the fluorescence spectrum shows double emission fluorescence peaks at 343 nm and 626 nm, which originate from the fluorescence emission of the synthesised C-dots and the additionally introduced C-dots, respectively. The relationship between the ratio of the intensity of the two emission peaks F343/F626 and the concentration of silver ions realises the analysis and detection of silver ions. The linear detection range of this method was 0.096–10 μM, and the detection limit (LOD, S/N = 3) was 32 nM. In addition, the method can also perform naked-eye visual detection according to the fluorescence colour change of the probe under ultraviolet light, and realise the rapid monitoring of Ag+ on site. The P-CDs/R-CDs ratiometric fluorescence sensor provides a new method for the detection of Ag+ and promotes the development of heavy metal ion sensing.
研究领域:
分析化学
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环境科学
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纳米材料科学
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产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）