PHYSIOLOGIA PLANTARUM
·
2018
·Vol. 165
·期 2
·155-168
·
IF 2.58
Wasim Ibrahim,Cheng-Wei Qiu,Can Zhang,Fangbin Cao,Zhu Shuijin,Feibo Wu
Soil salinity and drought are the two most common and frequently co-occurring abiotic stresses limiting cotton growth and productivity. However, physiological mechanisms of tolerance to such condition remain elusive. Greenhouse pot experiments were performed to study genotypic differences in response to single drought (4% soil moisture; D) and salinity (200 mM NaCl; S) stress and combined stresses (D + S) using two cotton genotypes Zhongmian 23 (salt-tolerant) and Zhongmian 41 (salt-sensitive). Our results showed that drought and salinity stresses, alone or in combination, caused significant reduction in plant growth, chlorophyll content and photosynthesis in the two cotton genotypes, with the largest impact visible under combined stress. Interestingly, Zhongmian 23 was more tolerant than Zhongmian 41 under the three stresses and displayed higher plant dry weight, photosynthesis and antioxidant enzymes activities such as superoxide dismutase (SOD), peroxidase (POD) catalase (CAT) and ascorbate peroxidase (APX) activities compared to control, while those parameters were significantly decreased in salt-stresses Zhongmian 41 compared to control. Moreover, Na + /K + -ATPase activity was more enhanced in Zhongmian 23 than in Zhongmian 41 under salinity stress. However, under single drought stress and D + S stress no significant differences were observed between the two genotypes. No significant differences were detected in Ca 2+ /Mg 2+ -ATPase activity in Zhongmian 41, while in Zhongmian 23 it was increased under salinity stress. Furthermore, Zhongmian 23 accumulated more soluble sugar, glycine-betaine and K + , but less Na + under the three stresses compared with Zhongmian 41. Obvious changes in leaf and root tips cell ultrastructure was observed in the two cotton genotypes. However, Zhongmian 23 was less affected than Zhongmian 41 especially under salinity stress. These results give a novel insight into the mechanisms of single and combined effects of drought and salinity stresses on cotton genotypes.
研究领域:
植物生理学
·
农学
·
胁迫生物学
✓ 已验证
DOI
PubMed
高影响因子
Virulence
·
2025
·
IF 5.4
Hao-Jie Shen,Jun-Feng Wang,Zheng-Jie Xue,Jia-Qi Shi,Bing Chen,Dong-Min Chen,Ni-Pi Chen,Yu-Dong Li,Chao-Dong Qian
Antimicrobial resistance is one of the greatest threats to global health. A thorough comprehension of the underlying processes through which bacteria evolve the ability to withstand diverse stressors is vital for the development of efficacious strategies to address this challenge. This study aimed to elucidate the mechanisms underlying the adaptation of an acrB-deficient strain of Escherichia coli ATCC 35218 (35218m) to sanguinarine (SAN), the main component of phytobiotic derived from Macleaya cordata. Analysis of the in vitro-selected SAN-resistant clones of strain 35218m led to the identification of a functionally uncharacterized TetR regulator, EefR. The regulator represses its own expression and that of four neighboring genes forming the eefRABCD operon, encoding components of a tripartite RND-efflux pump (EefABC) and a putative MFS-type exporter (EefD). Overexpression of these pumps reduces the susceptibility of acrB-deficient E. coli to SAN and structurally diverse antibiotics. The eefR-eefABC-eefD cluster, widely distributed across Enterobacteriaceae genomes, is also found on plasmids in several E. coli isolates, indicating a significant risk for the rapid spread of this multidrug resistance mechanism.
研究领域:
微生物学
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分子生物学
·
耐药机制
·
细菌遗传学
·
抗生素耐药性
✓ 已验证
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Wei Yu,Xinru Zhang,Muge Gu,Yihui Zhang,Xiangqi Zhang,Jiayu Wang,Genjiang Zheng,Wei-En Yuan
Peripheral nerve injuries, often caused by trauma and tumor resection, severely impair motor and sensory functions. While autologous nerve grafting remains the gold standard, its efficiency is hindered by limited donor tissue availability, donor site morbidity, and neuropathic pain. Tissue-engineered nerve grafts, emerging as promising alternatives, still face challenges due to the lack of essential biochemical and biophysical cues for comprehensive nerve regeneration. This study introduces a Janus Mg 2+ /H 2 pump conduit, constructed with a MgH 2 @PLGA middle layer, polycaprolactone (PCL) outer layers, and a polydopamine-coated PCL (PCL@PDA) inner layer. The PCL provides structural support, while the MgH 2 @PLGA layer continuously releases Mg 2+ and H 2 as biochemical cues, driven by an acidic microenvironment and the MgH 2 -water reaction. PDA modification of the inner layer, serving as biophysical cues, further increases cell adhesion. Mg 2+ released from the conduit mitigates oxidative stress in Schwann cells and increases their expression of neurotrophic factors, while the H 2 attenuates inflammation, aiding nerve regeneration. In a rat sciatic nerve defect model, the conduit shows enhanced functional, electrophysiological, and histological recovery. These findings highlight the potential of Janus Mg 2+ /H 2 pump conduit as a promising approach for peripheral nerve defect repair by offering a conducive microenvironment.
研究领域:
神经科学
·
生物材料学
·
再生医学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF LUMINESCENCE
·
2023
·
IF 3.6
Zuodong Liu,Yue Cao,Jiashun Wang,Siya Li,Qilong Shen,Yongsheng Yu,Bingchu Mei,Qiangshan Jing,Peng Liu
Near-infrared pumped up-conversion luminescent PrF 3 and YbF 3 co-doped SrF 2 ceramics were fabricated by the hot-pressing sintering technique, and the pellets were transparent with a primrose yellow appearance. The influence of YbF 3 co-doping levels on the optical qualities and microstructures of ceramics was investigated. We identified the mechanisms to realize up-conversion luminescence in the visible range from 3 P 0,1 levels (Pr 3+ ) under near-infrared wavelength pumping sources other than the near ultraviolet to blue region photons. Yb 3+ ions inducing a broad and intense absorption band at the 900–1050 nm region, and the absorption coefficient and cross-section at 980 nm are 7.57 cm −1 and 4.19 × 10 −21 cm 2 in the ceramic co-doped with 15 wt% YbF 3 , respectively. The intense up-conversion luminescence bands at 480, 520, 540, and 600 nm under 980 nm excitation were attributed to 3 P 0 → 3 H 4 , 3 P 1 → 3 H 5 , 3 P 0 → 3 H 5 and 1 D 2 → 3 H 4 transitions of Pr 3+ ions, respectively.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-16
·
IF 15.7
Li Ke,Hu Sihan,Li Hanwen,Lin Wenzheng,Zhao Duoyi,Xu Zhuobin,Pan Chun,Wang Huihui,Li Dandan,Liu Jingjing,Chen Hao
Resident leptin-receptor-expressing (LepR + ) cells senescence in the aged bone marrow impairs the regenerative capacity of osteo- and other lineages of cells. In this study, a LepR + cell-targeting nitric oxide (NO) nanopump with in vivo self-controlled turn-on ability was constructed to rejuvenate the LepR + cells in the aged bone marrow. The nanopump co-entrapped hydrophobic chemiluminescence substrate and NO donor into the matrix of amphiphilic polymer through a nanoprecipitation process. The chemiluminescence substrate in the NO nanopump automatically reacts with the accumulated H 2 O 2 in the aged bone marrow and then directly transfers the chemical energy to the NO donor to induce in situ NO release. The NO produced in situ within the aged bone marrow triggered the regeneration of the osteoblastic and the other niches in vivo through activating the glycolysis signaling in the senescent LepR + cells. Conclusively, the constructed NO nanopump is a promising tool to counter aging-induced bone marrow disorders.
研究领域:
生物学
·
医学
·
老年病学
·
生物材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Zewei Zhao,Zhiguang Wu,Sven Rutkowski,Sergei I. Tverdokhlebov,Johannes Frueh
Micropumps are in animal and human bodies and on cellular levels vital for the life functions. In case of critical problems like diseases, artificial micropumps are candidates to take over important functions. These functions are ranging from release of substances over removing toxics to stirring stomach fluids, helping to disperse medicine. We hereby present a Janus micropump, powered by hydrogen bubbles, which is able to operate in a gastric pH environment. This Janus micropump consumes hydrochloric acid as an external fuel and releases magnesium ions , which act as micronutrients . The presented Janus micropumps do display significant pumping power by moving external tracer particles and stop after exhausting their magnesium or alternatively acid fuel. The pumping properties depend significantly on the surrounding pH environment and the amount of external surfactant added. Analysis of tracer particle motion shows, that the cause of this movement are the bubbles generated that drag the liquid along after bubble release.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
DOI
高影响因子
Nature Communications
·
2021
·Vol. 12
·期 1
·1-11
·
IF 14.919
Tang Wei,Zhang Chao,Zhong Yiding,Zhu Pingan,Hu Yu,Jiao Zhongdong,Wei Xiaofeng,Lu Gang,Wang Jinrong,Liang Yuwen,Lin Yangqiao,Wang Wei,Yang Huayong,Zou Jun
Recent advances in soft materials enable robots to possess safer human-machine interaction ways and adaptive motions, yet there remain substantial challenges to develop universal driving power sources that can achieve performance trade-offs between actuation, speed, portability, and reliability in untethered applications. Here, we introduce a class of fully soft electronic pumps that utilize electrical energy to pump liquid through electrons and ions migration mechanism. Soft pumps combine good portability with excellent actuation performances. We develop special functional liquids that merge unique properties of electrically actuation and self-healing function, providing a direction for self-healing fluid power systems. Appearances and pumpabilities of soft pumps could be customized to meet personalized needs of diverse robots. Combined with a homemade miniature high-voltage power converter, two different soft pumps are implanted into robotic fish and vehicle to achieve their untethered motions, illustrating broad potential of soft pumps as universal power sources in untethered soft robotics.
研究领域:
材料科学
·
机器人学
·
生物医学工程
✓ 已验证
DOI
高影响因子
CHEMISTRY OF MATERIALS
·
2024
·
IF 7.2
Yichen Qi,Zeyang Zhang,Qinke Tang,Jiangchuan Liu,Rui Shi,Jiguang Zhang,Yana Liu,Jun Wang,Jiankun Zhang,Shihao Chen,Yunfeng Zhu
Catalysis has been demonstrated to be effective in enhancing the kinetics of MgH2, which has been widely investigated as one of the most promising solid-state hydrogen storage materials. It is essential and challenging to design catalysts with high activity and to understand the corresponding interaction mechanisms between the catalysts and MgH2, especially for multiphase catalyst systems. In this study, an elaborated VS2/NiS2 catalyst based on well-combined components and heterostructure is exploited to substantially improve the hydrogen storage performance of MgH2. Impressively, rapid dehydrogenation (3.4 wt % H2 in 900 s at 498 K) and low-temperature hydrogenation (3.7 wt % H2 in 7200 s at 348 K) properties are achieved in the MgH2–VS2/NiS2 system. The activation energies for the hydrogen absorption/desorption are calculated to be 32.1/86.7 kJ mol–1, which represents a considerable reduction of 60.9% and 43.6% compared to the as-milled MgH2, respectively. Detailed investigations reveal that the enhanced hydrogen absorption/desorption kinetics are mainly attributed to the synergistic effect induced by the in situ-formed Mg2Ni/VH2 heterostructure and the “hydrogen pump” of Mg2Ni/Mg2NiH4. The Mg2Ni/VH2 heterostructure elongate Mg–H bonds, while the “hydrogen pump” of Mg2Ni/Mg2NiH4 facilitate H transfer. This work offers a fresh perspective for application of multicomponent catalysts in the field of metal hydrides.
研究领域:
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
ACS Nano
·
2025
·
IF 16
Xueyang Ren,Xuefei Zhu,Xiaodong Shao,Wen Yang,Yanmei Meng,Shiyu Chen,Yannan Wang,Jianqing Li,Qin Jiang,Benhui Hu
Elevated intraocular pressure (IOP) is a major risk factor for blindness in glaucoma patients, highlighting the critical need for continuous IOP monitoring. While traditional transpalpebral tonometers (TTs) circumvent corneal contact by adopting Goldmann applanation principles through impulsive corneal flattening forces, their measurement accuracy is inherently compromised by eyelid-induced cushion effects. In contrast, parallel-plate capacitive sensors employ constant compressive loading upon the eyelid, achieving palpebral compaction to mitigate the cushion effects. More recently, ion-pump-based capacitive sensors have emerged as promising alternatives, particularly due to their enhanced sensitivity. Nevertheless, these sensors exhibit sharp sensitivity deterioration at extended measurement ranges (0–10 kPa). This operational constraint originates from the strong hydrogen bond energies (between confining matrices and ions) and rigid block copolymer matrices’ steric hindrance. To address these limitations, we developed a transpalpebral tonometer featuring low-energy-barrier ion pumps, incorporating (3-aminopropyl)triethoxysilane (APTES)-silanized liquid metal nanoparticles (LM NPs) as confining matrices and an ionic liquid as an ion donor. The low-energy barrier arises from (1) weaker hydrogen bonds between the N–H of APTES and the F of the ionic liquid and (2) reduced crystallinity in the elastomeric matrices induced by LM NPs. Our sensor achieves a sensitivity of 24.88 kPa–1 with maintained linearity over 0–85 kPa. In vivo animal trials over 120 min validated its continuous IOP monitoring capability, reliably detecting elevated IOP states and demonstrating clinical potential for glaucoma management.
研究领域:
医学工程
·
生物医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nano Research
·
2018
·Vol. 11
·期 4
·1810-1821
·
IF 7.994
Li Mingtong,Su Yajun,Zhang Hui,Dong Bin
A micropump induces the flow of its surrounding fluids and is extremely promising in a variety of applications such as chemical sensing or mass transportation. However, it is still challenging to manipulate its pumping direction. In this study, we examine a binary micropump based on perovskite and poly[(2-methoxy-5-ethylhexyloxy)-1,4-phenylenevinylene] (MEHPPV). The micropump is operational under the influence of light. Light exhibits significant versatility in controlling the pumping phenomenon of the micropump. It governs the start and stop and also regulates the velocity and directions. The direction control signifies immense opportunities for the development of micropumps with unprecedented pumping behaviors and functions (such as heartbeat-like pumping, rectification, and amplification). This makes them potentially useful in various fields. Hence, it is expected that the micropump reported in the current study could act as a key step towards the further development of more sophisticated micropumps for diverse applications.
研究领域:
材料科学
·
光学工程
·
微流控技术
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Xiaoqing Jiang,Jie Zou,Yongjian Ni,Yuheng Wang,Xianwei Qian,Xuebin Li,Shihao Wei,Yuanjie Su,Guangzhong Xie,Mingjun Zhou,Jiawen Jian
The catalytic activity of an oxygen-pumping electrode is very important to the performance of amperometric NO x (NO and NO 2 ) sensors. To enhance the stability of electrochemical NO x sensors based on Pt electrodes, we fabricated sensitive electrodes of Pt-based materials doped with small and different Au contents on 8% mol Y 2 O 3 -stabilized ZrO 2 (8YSZ) solid electrolyte substrates by screen printing and high-temperature co-firing. The effects of Au on the porous Pt electrode’s catalytic activity and long-term stability were investigated, and the results are as follows. First, the catalytic capacity of the Pt–Au alloy electrode decreases with increasing Au content due to the inhibition of the oxygen adsorption on Au, which decreases the amount of oxygen participating in the reaction at triple-phase boundaries (TPBs). Second, the catalytic ability of the alloy electrode decreases exponentially with aging time due to the reduction in the length of TPBs caused by the significant reduction in the number of holes in the electrode, and the oxidation of Pt. In addition, the conductivity decay rate of the electrode decreases with increasing Au doping. This indicates that Pt-based electrodes doped with varying Au contents, long-term, and high-temperature aging have notably regular effects on the catalytic activity of oxygen-pumping electrodes, for which we have developed a model of Au passivation and the synergistic effect of aging time on the activity of Pt-based oxygen-pumping electrodes.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2024
·Vol. 14
·期 6
·517
·
IF 4.4
Yunyu Sun,Hao Wang,Jiwei Jiang,Hui Zhang,Limei Liu,Keying Zhang,Bo Song,Bin Dong
Inspired by the collective behaviors of active systems in nature, the collective behavior of micromotors has attracted more and more attention in recent years. However, little attention has been paid to the collective behavior of the immobilized micromotor, i.e., the micropump. In this paper, a unique pentacene-based micropump is reported, which demonstrates dynamic collective behavior activated by white light irradiation. The light irradiation may generate the photochemical reactions between pentacene and water, leading to the electroosmotic flow. As a result, this micropump is capable of pumping the surrounding solution inward along the substrate surface based on the electroosmosis mechanism. Intriguingly, the inward pumping causes the agglomeration of the tracer particles on the surface of the micropump. In addition, the aggregation can migrate following the change in the light irradiation position between two adjacent micropumps. Based on the aggregating and migrating behaviors of this pentacene-based micropump, we have achieved the conductivity restoration of the cracked circuit.
研究领域:
材料科学
·
生物仿生学
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）