Journal of Energy Chemistry
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2016
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IF 2.322
Qi Wang,Neeraj Gupta,Guodong Wen,Sharifah Bee Abd Hamid,Dang Sheng Su
Vanillyl alcohol, which is made up of an aromatic ring , an alcoholic hydroxyl group, a phenolic hydroxyl group and a methoxy group, was selected as the model molecule of lignin. Various carbon materials supported Pd catalysts were chosen to catalyze the HDO of vanillyl alcohol. The catalysts were characterized via TEM, TPD, XRD, XPS and CO-chemisorption. It was found that different carbon materials could obviously influence the particle sizes, dispersion and distribution of Pd or PdO particles. Palladium and carbon can synergistically catalyze the room-temperature HDO of vanillyl alcohol even at room temperature, and the carboxyl group was found to be the effective active acid site during the reaction. Possible reaction mechanism was also proposed. The existence of the effective active acid sites on the carbon supports could obviously lower the reaction temperature without decreasing the selectivity, as a result, making the production of renewable fuels by HDO much more economically feasible, which is of much importance.
研究领域:
化学工程
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可再生能源
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DOI
高影响因子
CATALYSIS LETTERS
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2025
·Vol. 155
·期 4
·1-9
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IF 2.4
Zheng Zhe,Xiang Nian,Li Yinkun,Xu Siwei,She Guoqiang,Zhou Peng,Liu Bing
Ethanol is regarded as a promising and green hydrogen donor due to its easy and large-scale production from abundant biomass resources. In this work, a nitrogen-doped carbon-encapsulated Co catalyst (Co@NC-800) was synthesized by a simple pyrolysis process and demonstrated promising activity in the hydrodeoxygenation of sulfoxides and pyridine N-oxides, producing sulfide and pyridine with good yields ranging from 80.3 to 99.0%. Moreover, the activity of the Co@NC-800 catalyst remained stable after 5 runs, indicating good stability. Graphical
研究领域:
催化化学
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可再生资源利用
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DOI
高影响因子
JOURNAL OF CATALYSIS
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2019
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IF 7.723
Yu Xin,Lin Dong,Yong Guo,Xiaohui Liu,Yongfeng Hu,Yanqin Wang
Production of aromatic hydrocarbons through lignin hydrodeoxygenation (HDO) is of significant importance. Previously, we found that Ru/Nb 2 O 5 was an excellent catalyst for the conversion of lignin to arenes with relatively high selectivity (71%). Herein, we aim to clarify which properties of Nb 2 O 5 influence the activity and selectivity. Four Ru/Nb 2 O 5 catalysts with different Nb 2 O 5 morphologies were used in the HDO of 4-methylphenol. Intensive studies show that layered Nb 2 O 5 supported Ru has more Nb O groups (unsaturated NbOx sites) and highest Ru dispersion, which led to the highest activity and toluene selectivity, this was further confirmed by loading pre-synthesized Ru colloids in various Nb 2 O 5 . Finally, a Ru/Nb 2 O 5 catalyst with more unsaturated Nb O groups was designed and it was found that even with enzymatic lignin as the feedstock, the selectivity to arenes can reach up to 94.8% with the yield of hydrocarbons of 99.6%. This study provides a promising strategy for catalyst design towards the selective production of aromatic hydrocarbons from lignin.
研究领域:
催化化学
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可再生能源
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DOI
高影响因子
GREEN CHEMISTRY
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2023
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IF 9.8
Fengan Han,Guangyi Li,Yanting Liu,Aiqin Wang,Feng Wang,Tao Zhang,Ning Li
Olefins are important feedstocks in the production of fuels and many useful chemicals. Herein, cobalt molybdate (CoMoO4) was first synthesized by an environmentally friendly evaporation method and it exhibited excellent catalytic performance for the production of olefins by the selective hydrodeoxygenation (HDO) of ketones that can be derived from lignocellulose. On the basis of the characterization results, the excellent catalytic performance of CoMoO4 was attributed to its larger specific surface area, better pore structure, higher oxygen vacancy (or Mo5+ species) concentration, higher acid strength and higher concentration of acid sites. Under the optimized reaction conditions, 4-heptanone was almost completely converted to heptene, and a high carbon yield of heptene (96%) was achieved over a CoMoO4 catalyst with a Co/Mo atomic ratio of 0.8 (denoted as CoMoO4-0.8). The CoMoO4 catalyst is also active for the selective HDO of other lignocellulosic ketones (such as acetone, butanone, 2-pentanone, 3-pentanone, cyclopentanone, cyclohexanone, 5-nonanone and acetophenone) to their corresponding olefins.
研究领域:
催化化学
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可再生资源化学
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DOI
高影响因子
Molecular Catalysis
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2024
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IF 3.9
Zhiqin Li,Zongxuan Li,Meng Wu,Zegang Qiu,Yanan Zhu,Riguang Zhang
It is highly significant to develop effective catalysts made from non-precious metals for the hydrodeoxygenation (HDO) process of eugenol to propylcyclohexane. A triazine polymer (PAF-53) was employed as a template to synthesize a highly potential Co/NC-T (nitrogen-doped carbon modified by template) catalyst through one-pot pyrolysis method, aiming to facilitate the HDO reaction of eugenol. The results of the characterization indicated that Co nanoparticles (NPs) were incorporated within the structure of nitrogen-doped carbon. Adding the suitable quantity of PAF-53 could improve the distribution of Co NPs, increase the specific area and average pore diameter, and facilitate the generation of numerous carbon nanotubes that are sparse and porous. Furthermore, the incorporation of PAF-53 improved the interaction between Co and nitrogen-doped carbon, and endowed Co/NC-T with high mobile electrons. As revealed by density functional theory (DFT) calculations, the adsorption of eugenol molecules was obviously enhanced, and the parallel adsorption configuration was remarkably favorable. The conversion of eugenol over Co/NC-T-1:4 reached 100% and the selectivity of propylcyclohexane reached 98.4%, at 300 °C, 3 MPa H 2 and a liquid hourly space velocity of 12 h −1 . Moreover, the Co/NC-T-1:4 catalyst exhibited remarkable durability and scalability during the HDO process of eugenol.
研究领域:
催化化学
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材料科学
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可再生能源
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DOI
高影响因子
ACS Sustainable Chemistry & Engineering
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2024
·
IF 7.1
Cen Zhang,Tianyi Liu,Siyan Zou,Xinyi Liu,Binbin Zhou,Jiali Mu,Jing Cao
Improving both the activity and stability is of great importance for MoS2-based catalysts in the hydrodeoxygenation (HDO) reaction. Herein, we report the construction of monolayer CoMoS anchored on hydrophobic-reduced graphene nanoribbons (ML-CoMoS/rGNRs) which exhibited excellent activity and stability in the HDO of 4-methylphenol. The superior HDO activity was attributed to the single layer structure of MoS2, which allows the good exposure of abundant edge sites for accommodating Co promoters to form the Co–Mo–S active phase. Besides, the hydrophobicity of rGNRs enables the fast removal of H2O during the HDO reaction, which alleviates the sulfur loss and endows the excellent stability of supported CoMoS monolayers. Consequently, ML-CoMoS/rGNRs afforded 97.3% conversion and 98.4% toluene selectivity at 220 °C for at least five reaction cycles. This work provides novel insights for designing highly active and stable metal sulfide catalysts for the application in the HDO reaction.
研究领域:
催化化学
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材料科学
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DOI
高影响因子
FUEL
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2024
·
IF 6.7
Wenjing Zhang,Tinghu Wang,Yiming Gao,Yaru Xue,Furang Li,Chuanrui Pang,Jianye Fu,Xinmei Liu,Yuchao Lyu
The catalytic performance of bifunctional catalyst for one-step hydrodeoxygenation of fatty acid esters to bio-jet fuel is contingent upon the features of metal component and acid support. However, it remains challenging to simultaneously modulate these structural features with the impregnation method. Herein, the metal particle size, pore structures and acidity of Ni/Beta catalysts are regulated simultaneously during the citric acid-assisted impregnation process. The particle size of Ni over the Ni/Beta catalyst is greatly decreased due to the steric and coordination effect of citric acid on metal. The electron density of the small Ni particle is reduced by the enhanced electron transfer between Ni and Beta. Besides, the dealumination effect of citric acid on Beta zeolite reduces strong Brønsted acid sites and introduces 0.85 times more mesopores into the Ni/Beta catalyst, compared with the counterpart obtained by conventional impregnation method. The enhanced metal dispersion over the Ni/Beta catalyst promote hydrodeoxygenation of reactants and favor hydrodecarbonylation reaction path. The reduced Brønsted acid sites and abundant mesopores inhibit cracking of intermediate and products. The space–time yield of C 12 and C 11 reaches 33.4 mmol·g −1 ·h −1 in hydrodeoxygenation of methyl laurate which is the highest value reported.
研究领域:
催化化学
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能源科学
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材料科学
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DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2025
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IF 3.9
Changyong Li,Mengqing Zhou,Yun Zheng,Shengchun Hu,Liangliang Zhang,Changzhou Chen,Jianchun Jiang
In this study, a series of puffball carbon-supported catalysts were synthesized to facilitate the hydrodeoxygenation (HDO) of the lignin model compound vanillin (VAN) into 2-methoxy-4-methylphenol (MMP). The Co-ZIF/BC catalyst, prepared by loading ZIF-67 onto puffball carbon support, achieved a VAN conversion rate of 96.28% and a selectivity of 86.57% for MMP under reaction conditions of 240 °C and 1.5 MPa of H2 for 4 h. Based on the characterization results, it was found that the Co-ZIF/BC catalyst exhibited high crystal defects, a large specific surface area, and mesopore volume, as well as strong Lewis acid sites. Additionally, the Co–N bonds formed between Co nanoparticles and nitrogen increased the electron density on the catalyst surface. The abundant surface Co0 species enhanced hydrogen adsorption and dissociation, providing more active sites, which facilitated the activation of reactants and improved the efficiency of the catalytic reaction. The use of abundant and low-cost puffball materials in the preparation of the Co-ZIF/BC catalyst not only reduced production costs but also supported the sustainability of the catalytic process, aligning with the principles of green chemistry.
研究领域:
催化化学
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环境科学
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绿色化学
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产品关联
DOI
高影响因子
TOXICOLOGY MECHANISMS AND METHODS
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2025
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IF 2.7
Lan Yang,Yewen Lin,Wenping Xu,Yang Zhang
Reactive oxygen species (ROS)-induced DNA oxidative damage is a significant manifestation of oxidative stress in the body and is closely associated with the onset and progression of various diseases. Although Pyripyropene A (PPPA) exhibits anti-tumor and anti-inflammatory activities, its antioxidant and protective effects against DNA oxidative injury remain unclear. In this study, using a hydrogen peroxide-induced oxidative injury model of L02 cells, it was found that PPPA could significantly reduce intracellular ROS and malondialdehyde (MDA) levels, enhance the activities of catalase (CAT) and reduced glutathione (GSH), and increase the 2,2-Diphenyl-1-picrylhydrazyl (DPPH) clearance rate, confirming its antioxidant effect. Comet assay showed a reduction in DNA breakage, and down-regulation of phosphorylated histone (γ-H2AX) and 8-hydroxydeoxyguanosine (8-oxodG), indicating that it effectively alleviates DNA oxidative injury. Meanwhile, the upregulated expression of poly ADP-ribose polymerase (PARP) suggests that PPPA may promote repair by activating the DNA damage response (DDR). This study systematically clarify for the first time that PPPA exerts a protective effect by synergistically antioxidizing, reducing DNA injury, and potentially activating repair pathways, providing a theoretical basis for its application in neoplasm and oxidative stress-related diseases.
研究领域:
分子生物学
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药理学
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氧化应激
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肿瘤学
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毒理学
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细胞生物学
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药物代谢
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产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
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2019
·
IF 4.527
Sihong Li,Ishfaq Muhammad,Hongxiao Yu,Xiaoqi Sun,Xiuying Zhang
In this study, we identified AFB1 adducts as potential markers and investigated the role of curcumin in alleviating AFB1-induced liver damage by suppressing the production of AFB1 adducts and oxidative stress in AA broilers liver. A total of 64 one-day-old Arbor Acres (AA) broilers were randomly divided into four groups, including control group, AFB1 group (5 mg/kg AFB1), cur + AFB1 group (300 mg/kg curcumin+5 mg/kg AFB1) and curcumin group (300 mg/kg). Serum biochemical parameters, liver antioxidant abilities, AFB1 adducts and oxidative stress mechanism were studied in broilers. AFB1 administration accompany with signs of liver injury, including hepatic histological lesions, increased serum enzymes activities , decreased liver antioxidant enzymes activities and the suppression of ROS and 8-OHdG. Meanwhile, Nrf2/HO-1 pathway was depressed by AFB1 treatment. Immunohistochemistry and ELISA showed that AFB1 significantly increased AFB1-DNA adduct in liver ( p < 0.05) and AFB1-lysine adduct in serum ( p < 0.05). Importantly, supplementation of curcumin can ameliorate these alterations. Intriguingly, curcumin alleviated AFB1-induced toxicity and oxidative stress by inhibiting the generation of ROS, 8-OHdG and AFB1 adducts, and activated Nrf2 signaling pathway in broilers. Conclusively, our experiments suggest that curcumin could be considered as a potential agent for prevention of AFB1-induced toxicity and oxidative stress, and AFB1 adducts could be suitable therapeutic targets.
研究领域:
兽医学
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毒理学
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药理学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
FOOD AND CHEMICAL TOXICOLOGY
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2013
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IF 3.01
Hui Dong,Demei Xu,Lihua Hu,Lingrui Li,Erqun Song,Yang Song
Tetrachlorobenzoquinone (TCBQ) is an active metabolite of pentachlorophenol (PCP). Although the genotoxic effect of PCP has been comprehensively investigated, there is little known about TCBQ’s genotoxic effects. In the current study, TCBQ was tested for its genotoxicity using HepG2 cells as experimental model. To select the exposure concentration of interest, cell viability was measured and three concentrations were used for further investigation. In single cell gel electrophoresis (SCGE) assay, concentration-dependent increase in tail length, tail DNA percentage and tail moment were detected following TCBQ exposure. Micronucleus (MN) assay indicated TCBQ gradually increased MN frequency and decreased nuclear division index (NDI). Enzyme-linked immunosorbent assay (ELISA) and western blotting analyses both showed TCBQ caused histone H2AX phosphorylation (γ-H2AX). Furthermore, the elevation of 8-hydroxydeoxyguanosine (8-OHdG) and reactive oxygen species (ROS) level indicated TCBQ-induced genotoxicity is associated with oxidative stress. On the other hand, N-acetyl-cysteine (NAC) administration significantly protected cells from the genotoxic effect of TCBQ. Overall, our data suggested TCBQ exerted genotoxic effect possibly via an oxidative damage mechanism in HepG2 cells and this toxicity is prevented by pretreatment with NAC.
研究领域:
毒理学
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细胞生物学
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遗传学
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产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
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2018
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IF 6.653
Chang Wang,Xue Yang,Qi Zheng,Birget Moe,Xing-Fang Li
The developmental toxicity of water disinfection byproducts remains unclear. Here we report the study of halobenzoquinone (HBQ)-induced in vivo developmental toxicity and oxidative stress using zebrafish embryos as a model. Embryos were exposed to 0.5–10 μM of individual HBQs and 0.5–5 mM haloacetic acids for up to 120 h postfertilization (hpf). LC50 values of the HBQs at 24 hpf were 4.6–9.8 μM, while those of three haloacetic acids were up to 200 times higher at 1900–2600 μM. HBQ exposure resulted in significant developmental malformations in larvae, including failed inflation of the gas bladder, heart malformations, and curved spines. An increase in reactive oxygen species was observed, together with a decrease in superoxide dismutase activity and glutathione content. Additionally, the antioxidant N-acetyl-l-cysteine significantly mitigated all HBQ-induced effects, supporting that oxidative stress contributes to HBQ toxicity. Further experiments examined HBQ-induced effects on DNA and genes. HBQ exposure increased 8-hydroxydeoxyguanosine levels, DNA fragmentation, and apoptosis in larvae, with apoptosis induction related to changes in the gene expression of p53 and mdm2. These results suggest that HBQs are acutely toxic, causing oxidative damage and developmental toxicity to zebrafish larvae.
研究领域:
毒理学
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环境科学
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发育生物学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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