TALANTA
·
2017
·
IF 4.162
Rui Xiao,Xiaoting Zhang,Xiaona Zhang,Jiahua Niu,Minghua Lu,Xiuhua Liu,Zongwei Cai
In this article, a method for the analysis of flavors and fragrances including ethyl vanillin , trans-cinnamic acid, methyl cinnamate , ethyl cinnamate , and benzyl cinnamate in foods by HPLC with Fe 3 O 4 @GO nanocomposite as the adsorbent of magnetic solid-phase extraction was developed. The magnetic Fe 3 O 4 @GO nanocomposite was prepared and characterized by transmission electron microscope, infrared spectroscopy , X-ray diffraction and vibrating sample magnetometer. The as-prepared Fe 3 O 4 @GO nanocomposite was used as adsorbent for extraction and preconcentration of flavors and fragrances in foods. The extraction and desorption conditions including amount of materials, extraction time and desorption solvents were investigated. The analytes were separated within 10 min and detected with LODs ranged from 0.02 to 0.04 μg/mL. The recovery obtained from the analysis of spiked juice sample was between 71.5% and 112.4% with RSDs lower than 4.14%. The developed method was successfully applied to the analysis of real samples including orange juice, chocolate and fruit sugar.
研究领域:
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Sustainable Chemistry and Pharmacy
·
2025
·
IF 5.8
Qingfen Zhang,Dan Ge,Shengcheng Mi,Qi Lu
The bioactive properties of essential oil are strongly associated with their chemical composition. In this work, a novel method of salt-enhanced homogenization pretreatment coupled with solvent-free microwave extraction (HP-SSFME) was developed for extracting essential oil (KGEO) from fresh Kaempferia galanga rhizomes, which significantly improved the extraction efficiency. Gas chromatography was employed to measure the contents of the main active components, ethyl p -methoxycinnamate (EPMC) and ethyl cinnamate (EC) in the essential oil. The extraction process was optimized by the Box-Behnken Design using the comprehensive scores of the yields of EPMC, EC, and KGEO obtained by the entropy weight method. The optimal parameters were determined as follows: amount of sodium chloride was 1.60 %, homogenization speed of 15000 r/min, homogenization time of 4 min, microwave irradiation power of 300 W, microwave irradiation time of 23 min. Under these conditions, the KGEO yield was 5.10 %, EPMC yield was 3.81 %, EC yield was 0.89 %. Compared with the conventional methods, the HP-SSFME method not only significantly increased the extraction yield of KGEO but also remarkably enhanced the yields of EPMC and EC. Additionally, the HP-SSFME method has low CO 2 emission and energy consumption, highlighting its environmental friendliness. Moreover, in terms of antibacterial activity, the HP-SSFME outperformed other methods, demonstrating a more powerful and extensive inhibitory effect against a range of bacteria. This study provides a valuable reference for the efficient extraction and quality control of essential oils from Kaempferia galanga rhizomes.
研究领域:
植物化学
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环境科学
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食品科学
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2021
·
IF 2.694
Linmao Tang,Yuan Guo,Zuoxiang Zeng,Weilan Xue
The density and liquid heat capacity of propyl cinnamate were measured in the temperature range from 290.15 to 503.15 K by a pycnometer and automatic adiabatic calorimeter and correlated with temperature by the linear equation and quadratic polynomial, respectively. Vapor pressure data of propyl cinnamate were determined by the ebulliometric method at 419.15–559.15 K, and they are in accordance with the Antoine equation. The vaporization enthalpy ΔvapH (Tb) of propyl cinnamate at normal boiling point was attained based on the Clausius–Clapeyron equation. The standard enthalpy of vaporization ΔvapH (298.15 K) was calculated by the Othmer method and verified by the Watson relation.
研究领域:
物理化学
·
热力学
✓ 已验证
产品关联
DOI
高影响因子
THERMOCHIMICA ACTA
·
2023
·
IF 3.5
Ningrui Zhao,Jumei Xu,Zuoxiang Zeng,Weilan Xue
The density of (E)-isobutyl cinnamate at 297.95–535.20 K was measured using a capillary pycnometer and linearly related to temperature. The vapor pressure of (E)-isobutyl cinnamate at 420.15–570.05 K was measured by the ebulliometric method, and correlated by Antoine equation with an average relative deviation of 1.11 %. The vaporization enthalpy Δ vap H (T b ) of (E)-isobutyl cinnamate at normal boiling point was obtained based on the Clausius-Clapeyron equation. The standard vaporization enthalpy Δ vap H (298.15 K) was calculated to be 73.67±0.5 kJ·mol −1 by Othmer's method and verified by the Corresponding State Group Contribution (CSGC) method. The heat capacities at saturation vapor pressure ( C SL ) of (E)-isobutyl cinnamate were measured at 298.15–533.15 K by an automatic calorimeter and correlated by a quadratic polynomial.
研究领域:
物理化学
·
热力学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2015
·
IF 2.679
Xiangyang Liu,Chao Su,Xuetao Qi,Maogang He
In this work, new experimental values for the isobaric molar heat capacities of ethyl heptanoate and ethyl cinnamate are presented at temperatures ranging from (305 to 387) K and under pressures up to 16.3 MPa. The relative expanded uncertainty of the isobaric molar heat capacity is estimated to be less than 1%. The isobaric molar heat capacities of ethyl heptanoate and ethyl cinnamate rise with the increasing temperature and fall with the increasing pressure. Based on the experimental findings in our work and from the literature, the isobaric molar heat capacities of saturated fatty acid methyl esters and fatty acid ethyl esters are found to rise with the carbon number, while the isobaric molar heat capacity of aromatic ester ethyl cinnamate is lower than that of the saturated fatty acid ethyl ester with the same or less carbon number due to the unsaturation. A correlation is proposed for the isobaric molar heat capacities of ethyl heptanoate and ethyl cinnamate with a maximum absolute relative deviation of 0.5%.
研究领域:
物理化学
·
热力学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
·
2024
·
IF 1.5
Jumei Xu,Ningrui Zhao,Zuoxiang Zeng,Weilan Xue
In this work, the optimum process conditions and kinetics of the green synthesis of isobutyl cinnamate using deep eutectic solvents (DESs) as catalysts were investigated. Isobutyl cinnamate is a spice with low toxicity and is widely used in the food industry. However, there is a lack of reports on its green synthesis. Three DESs were prepared by adjusting the mixing ratio of choline chloride (ChCl) and p-toluenesulfonic acid (PTSA). Response surface methodology with Box-Behnken design (RSM-BBD) was used to optimize the process parameters of the esterification of cinnamic acid with isobutanol. The effects of catalyst loading, stirring speed, cinnamic acid/isobutanol molar ratio, and temperature on the conversion of cinnamic acid over time were evaluated. Using ChCl-PTSA as a catalyst, the kinetics data and chemical equilibrium constants of the esterification were determined at a temperature range of 353.15–383.15 K. The pseudo-homogeneous (PH) model based on activity was then adopted to describe the kinetics of the reaction, and the relative deviations between the experimental values and the calculated ones by PH model are less than 5.5%. Thermodynamic data (Δ r H 0 , Δ r S 0 , Δ r G 0 ) for the esterification reaction was calculated as well. In addition, the results of six consecutive cycles of the catalyst showed that ChCl-PTSA has good stability and recyclability.
研究领域:
有机化学
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催化化学
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食品科学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2010
·
IF 2.962
Rong Hu,Yu-Yun Chen,Li-Ming Zhang
A novel polysaccharide derivative with photoreactivity was prepared by the conjugation of carboxymethylated chitosan with N -hydroxyl succinimide-activated nitrocinnamate in the presence of N , N -dicyclohexylcarbodiimide, and characterized by IR, 1 H NMR, UV–vis and rheological analyses. It was found that such a modified polysaccharide could exhibit an unique photogelation ability in the absence of potentially toxic photoinitiator or catalyst and be suitable particularly for the in situ preparation of photocrosslinked hydrogel biomaterials. By changing the photoirradiation time and incorporated nitrocinnamate content, its photogelation property could be modulated. For the resultant hydrogels incorporated with various nitrocinnamate contents, their properties such as swelling, viscoelasticity, in vitro biodegradation and drug release were investigated. In addition, the photogelation mechanism of this polysaccharide derivative was also discussed.
研究领域:
生物材料
·
药剂学
·
高分子化学
✓ 已验证
DOI
PubMed
高影响因子
PLoS One
·
2017
·Vol. 12
·期 4
·e0176189
·
IF 2.806
Kun Zhou,Dongdong Chen,Bin Li,Bingyu Zhang,Fang Miao,Le Zhou
A series of cinnamic acid esters and their derivatives were synthesized and evaluated for antifungal activities in vitro against four plant pathogenic fungi by using the mycelium growth rate method. Structure−activity relationship was derived also. Almost all of the compounds showed some inhibition activity on each of the fungi at 0.5 mM. Eight compounds showed the higher average activity with average EC 50 values of 17.4–28.6 μg/mL for the fungi than kresoxim-methyl, a commercial fungicide standard, and ten compounds were much more active than commercial fungicide standards carbendazim against P . grisea or kresoxim-methyl against both P . grisea and Valsa mali . Compounds C1 and C2 showed the higher activity with average EC 50 values of 17.4 and 18.5 μg/mL and great potential for development of new plant antifungal agents. The structure−activity relationship analysis showed that both the substitution pattern of the phenyl ring and the alkyl group in the alcohol moiety significantly influences the activity. There exists complexly comprehensive effect between the substituents on the phenyl ring and the alkyl group in the alcohol moiety on the activity. Thus, cinnamic acid esters showed great potential the development of new antifungal agents for plant protection due to high activity, natural compounds or natural compound framework, simple structure, easy preparation, low-cost and environmentally friendly.
研究领域:
植物病理学
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农药化学
·
天然产物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Jinhang Chen,Yi Zhang,Huaying Zhong,Hao Zhu,Hongxun Wang,Kheng-Lim Goh,Juntao Zhang,Mingming Zheng
Green and effective synthesis of flavor esters is a long-term interest in food, cosmetic and pharmaceutical industries. Here, an immobilized lipase microarray was prepared by immobilizing lipase CSL on hydrophobically modified ordered mesoporous silicon (CSL@OMS-C 8 ) for the enzymatic production of cinnamic esters with different flavors. The results showed that the CSL@OMS-C 8 , with an immobilization capacity of 249.3 ± 11.1 mg/g, exhibited 1.6 times higher catalytic activity than that of free lipase at the optimum temperature of 70 °C. The maximum yield of benzyl cinnamate reached 97.3% in 2 h with the corresponding CE value of 650.5 μmol/g · h, leading to the highest record compared to the current literature. Besides, the CSL@OMS-C 8 could maintain 81.4 ± 1.1% conversion for cinnamic acid after five-cycle reuse, thus revealing the high stability and reusability of immobilized lipase. Finally, the broad applicability of the immobilized lipase microarray was confirmed by its capacity to successfully catalyze the synthesis of methyl cinnamate, ethyl cinnamate, butyl cinnamate, geranyl cinnamate and isoamyl cinnamate. This study reveals new insights on the efficient and sustainable enzymatic approach to produce natural cinnamic acid flavor esters and, consequently, could pave the way for the natural and clean production in food industries.
研究领域:
食品科学
·
生物催化
·
绿色化学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2023
·
IF 5.9
Peng Deng,Yuyang Zhou
The combination of green chemicals with biodegradable polymers is highly encouraged to enhance the sustainability of textiles and their manufacturing process. Polylactic acid (PLA) is a promising biodegradable polymer to replace petroleum-based fibres and fabrics. However, to enhance the compatibility between PLA and bio-based dyes or finishes is still a challenging issue. This study achieves a simultaneous bio-colouration/finishing on PLA using quercetin, especially focusing on the adsorption enhancement with a food-grade methyl cinnamate (MC). Results show that the exhaustion of quercetin on PLA is significantly enhanced from 26% to 64% using MC. At similar concentrations, MC enables much better colour depth ( K/S ) improvement on PLA than synthetic n-amyl acetate. The factorial significance follows the order: MC concentration > quercetin concentration > temperature. Under the optimal condition (0.97 g/L quercetin, 3.0 g/L MC, at 103.5 o C), a theoretical highest K/S of 6.15 can be achieved. PLA treated with quercetin/MC displays much higher b* value than that of the PLA only treated with quercetin. MC also increases colour uniformity of the PLA treated with quercetin. Quercetin/MC efficiently decreases UVB and UVA transmittance of PLA and reaches the UPF 50 + rating. Around 98% of free radicals were scavenged by 10%owf quercetin/MC treated PLA in 30 min. The marginal tensile loss (<5%) of PLA after treatment is acceptable in wet processing. In all, the strengthened colour shade and functionality of PLA using MC stemms from the adsorption enhancement, which expands the applicable area of PLA.
研究领域:
纺织科学
·
绿色化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Jing Li,Xiang-Dong Xu,Jian Zhang,Xin-Yi Sui,Jian-Bo Qu
Macroporous polystyrene microspheres have been extensively used as an efficient carrier for lipase immobilization owing to the hydrophobic surface , excellent mechanical strength and chemical stability, easy to recycle and low cost. However, conventional polystyrene microspheres usually have a pore size of less than 100 nm and an extremely hydrophobic surface lacking functional groups, which bring a series of problems such as low enzyme loading, activity recovery, reusability, serious leakage, and high substrate diffusion limitation. In this work, a novel generation of gigaporous polystyrene microspheres with moderately hydrophilic surfaces was specifically designed as an enzymatic carrier. The microspheres were featured with micropores (∼ 9 nm), mesopores (∼ 54 nm), and gigapores (∼ 948 nm), ensuring native enzyme structure preservation and high loading capacity. After epoxy activation, the lipase PS from Burkholderia cepacia (PPL) was site-specifically immobilized onto the microspheres. The resultant immobilized PPL exhibited 95 % activity recovery at a maximum loading of 115.3 mg/g. Also, the immobilized PPL surpassed free PPL in pH and temperature tolerances, temperature and storage stabilities, and achieved a 91.6 % yield in benzyl cinnamate biosynthesis. Besides, excellent reusability of the immobilized PPL was demonstrated with an 80.1 % yield after 10 cycles. Overall, these gigaporous microspheres show great potential for the highly efficient immobilization of lipase and enhanced benzyl cinnamate production.
研究领域:
生物化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2022
·Vol. 12
·期 10
·1265
·
IF 4.501
Lihua Du,Lingyan Zheng,Yue Pan,Zhikai Sheng,Shiyi Zhang,Hang Lin,Aoying Zhang,Hanjia Xie,Xiping Luo
While a few derivatives of cinnamamides exhibited anti-inflammatory and/ or analgesic activity, in this study, we developed a highly efficient method for the synthesis of cinnamamides from methyl cinnamates and phenylethylamines catalyzed by Lipozyme®TL IM in continuous-flow microreactors. The reaction parameters and broad substrate range of the new method was studied. Maximum conversion (91.3%) was obtained under the optimal condition of substrate molar ratio of 1:2 (methyl 4-chlorocinnamate: phenylethylamine) at 45°Cfor about 40 min. The remarkable features of this work include short residence time, mild reaction conditions, easy control of the reaction process, and that the catalyst can be recycled or reused, which provide a rapid and economical strategy for the synthesis and design of cinnamamide derivatives for further research on drug activity.
研究领域:
有机化学
·
药物化学
·
生物催化
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）