RNHSO2F as reliable azasulfene precursors for the construction of sulfamates
Here we report the utilization of NH-sulfamoyl fluorides (RNHSO2F) as reliable SuFEx synthons for the construction of various sulfamate esters. By using potassium fluoride as base, we are able to convert RNHSO2F to azasulfene intermediates under mild conditions and guarantee their further efficent ligation with phenols and alcohols.
研究领域:
有机化学
·
合成化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）