Journal of Physical Chemistry C
·
2022
·
IF 4.177
Xueying Chen,Yeqing Chen,Jie Huang,Chen Li,Zongming Ni,Kang Zhang,Mingxuan Cao,Ting Yu,Yan Chen,Xin He,Yang Li
Cubic-phase CsPbI3 perovskite nanocrystals (CsPbI3 NCs) are widely used as a promising luminescent material in optical devices such as light-emitting diodes and lasers due to their high photoluminescence quantum efficiency and excellent color purities. However, the CsPbI3 lattice is more likely to face the problem of phase transformation due to the poor thermodynamic stability, which would lead to the decrease of its photoluminescence quantum efficiency. In this work, α-CsPbI3 NCs were synthesized by the room-temperature dual-ligand-assisted re-precipitation method under the synergistic effect of n-octanoic acid (OTAC), oleylamine (OLA), and (3-aminopropyl)triethoxysilane (APTES). The anionic OTAC and cationic OLA ligands interacted with the Pb2+ and I–, respectively, on the surface of the α-CsPbI3 NCs to passivate the defects on the surface. By the adjustment to the volume ratio of the OTAC to OLA, the synergistic effects of the dual ligands inhibited the distortion of the octahedral [PbI6]4– and maintained the cubic perovskite structure of the α-CsPbI3 NCs. The hydrolysis of APTES into the silica layer would provide efficient environmental protection and maintain the cubic phase of α-CsPbI3 at room temperature. The α-CsPbI3 NCs not only produce strong red emission upon the UV excitation but also exhibit strong up-conversion luminescent properties upon the near-infrared excitation at a low excitation power laser of 1064 nm, showing dual-mode luminescent characteristics as a promising material for potential applications in optical devices.
研究领域:
材料科学
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光电子学
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纳米技术
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光子学
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产品关联
DOI
高影响因子
Case Studies in Thermal Engineering
·
2024
·
IF 6.4
Wenjun Zhao,Zhisheng Xu,Long Yan,Guoqing Niu
The research of short-chain fluorocarbon surfactants is crucial in effectively and environmentally extinguishing petrochemical fires. In this study, a short-chain fluorocarbon surfactant named 2 H ,2 H -perfluorooctanoic acid sodium salt (PFH-CA) was synthesized, and then characterized its chemical structure, thermal stability, surface activity, and foam property. Subsequently, PFH-CA was compounded with hydrocarbon surfactants including sodium dodecyl sulfate (SDS), dodecyl trimethyl ammonium chloride (DTAC), and N , N -dimethyldodecylamine- N -oxid (OB-2) at different molar ratios. The surface tension, interaction parameters, and foam property of the PFH-CA/hydrocarbon surfactant compounding systems were investigated. The analysis indicates that PFH-CA exhibits excellent surface activity and thermal stability concomitant with poor foam property. Introducing SDS, DTAC, and OB-2 enhances the foam performance and reduces the consumption of PFH-CA through synergistic interactions. Especially, PFH-CA/DTAC (1:4) system possesses the strongest interactions and the best performance, with critical micelle concentration ( CMC ) and surface tension at CMC ( γ CMC ) of 0.11 mmol/L and 20.90 mN/m, respectively. When concentration of PFH-CA exceeds 0.5 mmol/L, the foaming ability and foam stability stabilize at 30 cm and 90 %, respectively. The enhanced performance of PFH-CA/DTAC system is attributed to the electrostatic attraction between anionic and cationic surfactants, which facilitates the formation of micelles, subsequently leading to better surface activity and foam properties.
研究领域:
化学
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材料科学
·
消防安全工程
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2024
·
IF 5.6
Yiping Sun,Xiaofang Yang,Jiayi Hu,Fuchun Ji,Huajian Chi,Ya Liu,Kan Hu,Fangfang Hao,Xiaodong Wen
In this study, the one-step switchable hydrophilic solvent (SHS)-based effervescence tablet microextraction (ETME) was coupled with smartphone digital image colorimetry (SDIC) for the field detection of nickel ion (Ni 2+ ) for the first time. Both extractant and CO 2 were generated in situ when the novel SHS-based effervescence tablet was placed in the sample solution. The complexant 1-(2-pyridinylazo)-2-naphthaleno (PAN) dissolved from the effervescence tablet to form a stable complex with Ni 2+ , and the extractant was uniformly dispersed in the sample solution under the action of CO 2 and fully in contact with Ni-PAN, which enabled efficient extraction of Ni 2+ . The color changes of the extraction phase were captured by smartphone, then a quantitative relationship between the concentrations of Ni 2+ and color intensity of images captured using a smartphone was established by customized applet WASDIC, which realized quantitative analysis of Ni 2+ in different samples. Under optimal conditions, the enhancement factor (EF) of the proposed method was 65.1, the limit of detection (LOD) and limit of quantification (LOQ) were 1.69 and 5.64 μg L −1 , respectively. The developed method was successfully applied to the detection of trace Ni 2+ in the environmental samples and natural medicines. And the applicability of the method for use in field analysis was validated.
研究领域:
分析化学
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环境科学
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医学检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2013
·
IF 4.612
Hong-Fei Tong,Dong-Qiang Lin,Dong Gao,Xiao-Ming Yuan,Shan-Jing Yao
Hydrophobic charge-induction chromatography (HCIC) is a novel downstream bioprocessing technology for antibody purification and it has several advantages over traditional purification processes. However, its separation selectivity still needs to be improved. In this work, sodium caprylate (NaCA) was used as the selective modifier to improve IgG purification from serum albumin containing feedstock with a typical HCIC resin, MEP HyperCel. The effects of NaCA on the adsorption equilibrium of bovine serum immunoglobulin G (IgG) and bovine serum albumin (BSA), as well as the dynamic binding and displacement behaviors were investigated. The binding and elution behaviors of these two proteins in the column were studied. It was found that adding 50–75 mM NaCA in the liquid phase could effectively reduce the adsorption of BSA on the MEP resin, but the same treatment has little influence on the adsorption of IgG. Moreover, the mechanism of the competitive binding between caprylate and MEP ligands on the surface of BSA is discussed. It was found that by controlling NaCA addition in the loading or washing buffer, the process efficiency of IgG purification from BSA containing feedstock can be improved, and the purity of IgG could reach to over 98%. The results indicated that caprylate could be a promising albumin-selective modifier to improve the separation efficiency of antibodies with the HCIC process.
研究领域:
生物技术
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蛋白质纯化
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抗体工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
·
2016
·
IF 1.451
Baogui Wang,Jing Fu,Lumin Li,Deming Gong,Xuefang Wen,Ping Yu,Zheling Zeng
Accumulation of lipids in the liver can lead to cell dysfunction and steatosis, an important factor in pathogenesis causing non-alcoholic fatty liver disease. The mechanisms related to lipid deposition in the liver, however, remain poorly understood. This study was aimed to investigate the effects of medium-chain fatty acid (MCFA) on the lipolysis and expression of lipid-sensing genes in human liver cells with steatosis. A cellular steatosis model, which is suitable to experimentally investigate the impact of fat accumulation in the liver, was established in human normal liver cells (LO2 cells) with a mixture of free fatty acids (oleate/palmitate, 2:1) at 200 μm for 24 h incubation. MCFA was found to down-regulate expression of liver X receptor-α, sterol regulatory element binding protein-1, acetyl-CoA carboxylase, fatty acid synthase, CD 36 and lipoprotein lipase in this cellular model, and have positive effects on adipose triglyceride lipase and hormone-sensitive lipase. These results suggest that MCFA may reduce lipid accumulation by regulating key lipid-sensing genes in human liver cells with steatosis.
研究领域:
肝病学
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分子生物学
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细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
·
2025
·
IF 4.9
Min Jia,Hao Yue,Xiuxiu Wang,Aizhen Zong,Tongcheng Xu,Yong-Jiang Xu,Yuanfa Liu
Medium-chain triacylglycerol (MCT) is a healthy lipid mainly composed of medium-chain fatty acids (MCFA), which has been proven to have physiological activities in improving metabolic disorders, reducing blood cholesterol, and controlling weight. Brown adipose tissue (BAT) has been regarded as a potential organ to fight obesity due to the function of thermogenesis and energy dissipation. Previous reports found that a diet rich in MCT contributed to the activation of BAT. However, the potential mechanism between MCT and BAT remains unknown. In the current study, MCFA was applied on C3H/10T1/2 cells differentiated brown adipocytes, and MCT was applied on high-fat diet (HFD) induced obese mice. The results showed that MCFA and MCT induced browning of adipocytes and activation of BAT, significantly increased the enrichment of mitochondria, and significantly reduced intracellular lipid accumulation and body weights in vivo and in vitro . Mechanically, MCT significantly increased the level of UCP1, AMPK, and the downstream signaling factors of Pgc1α and Ulk1 , further significantly elevated the brown differentiation factor of Pparγ . Moreover, The AMPK inhibitor dorsomorphin partially impaired the beneficial effects caused by MCT. In conclusion, this study proved that AMPK is the potential target of MCT to induce BAT activation and provided theoretical evidence for the application of MCT in the future.
研究领域:
营养学
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代谢生物学
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分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Science & Nutrition
·
2020
·Vol. 8
·期 7
·3590-3601
·
IF 1.797
Jun Yang,Ting Peng,Jiyong Huang,Guohua Zhang,Jiaheng Xia,Maomao Ma,Danwen Deng,Deming Gong,Zheling Zeng
Drug-induced liver injury (DILI) is one of the common adverse effects of drug therapy, which is closely associated with oxidative stress, apoptosis, and inflammation response. Medium-chain fatty acids (MCFA) were reported to relieve inflammation and attenuate oxidative stress. However, little has been known about the hepatoprotective effects of MCFA in DILI. In the present study, acetaminophen (AP) and rifampicin (RFP) were used to establish DILI models in LO2 cells, and the cytoprotective effects of MCFA on hepatocellular injury were investigated. Results showed that the optimal condition for the DILI model was treatment with 10 mM AP or 600 µM RFP for 24 hr. LCFA treatment markedly reduced the cell viability and increased the activities of alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase. Meanwhile, LCFA treatment aggravated cell apoptosis, mitochondrial dysfunction, and oxidative stress. The mRNA and protein expression levels of inflammatory cytokines (IL-1β and TNF-α) were significantly elevated by LCFA. In contrast, MCFA treatment did not significantly affect cell viability, apoptosis, oxidative, stress and inflammation, and it did not produce the detrimental effects on DILI models. Therefore, we proposed that MCFA may be more safe and suitable than LCFA as nutrition support or the selection of daily dietary oil and fat for the patients with DILI.
研究领域:
药理学
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毒理学
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肝病学
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细胞生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Han Jia,Shaoyan Wang,Zhe Wang,Qiang Wang,Haidong Jia,Lin Song,Xuwen Qin,Fangning Fan,Zhe Li,Pan Huang
Ionic liquids (ILs) have been introduced as novel high-performance shale inhibitors. The inhibition performance and mechanism of the cation groups in ILs have been widely investigated, whereas the effects of the anionic groups in ILs on the inhibitory capacity have rarely been reported. In this work, a series of fatty acid-based ionic liquids (FAILs) with different anionic groups, methyltrioctylammonium octanoate ([N 8881 ][C 8:0 ]), methyltrioctylammonium laurate ([N 8881 ][C 12:0 ]), and methyltrioctylammonium palmitate ([N 8881 ][C 16:0 ]), were synthesized to evaluate their inhibition ability via the sodium bentonite (Na-Bent) immersion test, the linear swelling test, and the shale hot-rolling recovery test. Compared with the traditional inhibitor KCl (2 wt%), FAIL [N 8881 ][C 8:0 ] showed greater inhibition performance at a much lower concentration (0.1 wt%). The inhibition mechanism of FAILs was further analysed by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), zeta potential measurements, and contact angle measurements. It was speculated that the best inhibition ability and thermal stability of [N 8881 ][C 8:0 ] should be attributed to the intensive interaction and the size-matching effect between cationic and anionic groups. The present study provided novel insight into the research and development of high-efficiency shale inhibitors.
研究领域:
石油工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD SCIENCE
·
2016
·Vol. 81
·期 3
·H794
·
IF 1.649
Baogui Wang,Lumin Li,Jing Fu,Ping Yu,Deming Gong,Cheng Zeng,Zheling Zeng
Nonalcoholic fatty liver disease (NAFLD) is closely associated with obesity-related metabolic complications, which caused by excess energy intake and physical inactivity apart from genetic defects. The mechanisms that promote disease progression from NAFLD to further liver injury are still unclear. We hypothesize that the progression involved “2nd hit” is strongly influenced by the type of fatty acids in diets. Flow cytometric analysis showed that medium-chain fatty acid (MCFA) markedly decreased the percentage of late apoptotic and necrotic cells compared with long-chain fatty acid (LCFA), and MCFA inhibited the activities of caspase-3 and -9 in human liver cells with steatosis. Western blot analysis found that the levels of inflammatory markers (interleukin [IL]-6, IL-1-β, and tumor necrosis factor-α) were substantially reduced by MCFA compared with LCFA. Proteomic analysis further showed that LCFA inhibited the expression of antioxidant enzymes, and increased the expression of proteins associated with oxidative stress. It was found that LCFA (palmitate), not MCFA induced apoptosis, oxidative stress and chronic inflammatory responses in the hepatic cells with steatosis. In conclusion, reasonable selection of dietary fats has potential to translate therapeutically by ameliorating disease progression in patients with NAFLD.
研究领域:
肝病学
·
营养学
·
细胞生物学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Han Jia,Shaoyan Wang,Yingbiao Xu,Tingyi Wang,Lingyu Zhang,Jinyong Song,Xuehao Zhang,Lin Song,Haidong Jia,Hui Yan
Ionic liquids are regarded as the promising and efficient additives to use in various aspects of petroleum industry , especially in chemical EOR. In this investigation, three novel fatty acid ionic liquids (FAILs), methyltrioctylammonium octanoate ([N 8881 ][C 8:0 ]), methyltrioctylammonium laurate ([N 8881 ][C 12:0 ]) and methyltrioctylammonium palmitate ([N 8881 ][C 16:0 ]), were selected and evaluated for their performances in terms of surface/interfacial activity, temperature and salt resistances. The three FAILs could cause remarkable reduction of surface tension to ~30mN/m in their aqueous solutions, and the [N 8881 ][C 8:0 ] with the shortest anionic alkane chain exhibited the greatest surface activity among three FAILs. Then the size-match effect and intermolecular interaction were employed to explain the abnormal variations, which were confirmed by the control experiments using mixed surfactants and the molecular dynamics simulation . It was found that the binding energy in [N 8881 ][C 8:0 ] (−28.961 kcal/mol) was larger than that in [N 8881 ][C 16:0 ] (−22.942 kcal/mol), which should be responsible for their different surface activity. Moreover, the crude oil/water interfacial tension (IFT) could be decreased to the much level (4.9 ×10 −3 mN/m and 1.7 × 10 −2 mN/m) even at high-temperature conditions (80 °C) and at high-salinity conditions (100,000 mg/L), indicating the FAILs might be the ideal candidate for the EOR used surfactants with great temperature and salt tolerances. Meanwhile, the variations of IFT results further verified our proposed mechanism.
研究领域:
化学工程
·
石油科学
·
界面科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2020
·
IF 5.065
Xu Jing,Xiaoyu Cheng,Wenfei Zhao,Huihui Wang,Xiaowen Wang
A method for the determination of triazine herbicides in water samples was established by magnetic effervescence tablet-assisted switchable hydrophilicity solvent-based liquid phase microextraction procedure (META-SHS-LPME) coupled with high-performance liquid chromatography with diode array detection. The magnetic effervescence tablet, composed of citric acid , sodium hexanoate, sodium bicarbonate, and Fe 3 O 4 nanoparticles , combined extractant generation, dispersion, and magnetic recovery into one step. Citric acid could react with sodium hexanoate and sodium bicarbonate to generate hexanoic acid and carbon dioxide in situ , respectively. Carbon dioxide bubbles assisted the eco-friendly extractant hexanoic acid to fully contact with target compounds. Fe 3 O 4 nanoparticles containing extractant and triazine herbicides were isolated from the sample solution using an external magnet. Good linearity was achieved in the range of 50–5000 ng mL −1 with a correlation coefficient greater than 0.997. The limit of detection was within 0.10–0.13 ng mL −1 . The extraction recovery of triazine herbicides were 81.4–96.7% in well, pond, and river waters. Overall, the proposed method was a simple, efficient, and eco-friendly analytical approach for determining triazine herbicide residues in water samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2022
·
IF 4.52
Haoyue Xue,Liyan Jia,Haijuan Jiang,Shu Qin,Yukun Yang,Junxue Wu,Xu Jing
A simple, efficient, and environmentally friendly method for the determination of pyrethroids and cadmium in drink samples was developed by successive homogeneous liquid-liquid microextraction (SHLLME) based on switchable hydrophilicity solvents and ionic liquids coupled with high-performance liquid chromatography-diode array detector (HPLC-DAD) and graphite furnace atomic absorption spectrometry (GFAAS) detection. The extraction of pyrethroids needs to be conducted under acidic conditions, while cadmium needs to be extracted under neutral or slightly alkaline conditions. In SHLLME, hydrophobic fatty acids and ionic liquids were generated in situ as extraction solvents for pyrethroids and cadmium, respectively. Acidic ionic liquids and sodium carbonate were successively applied to adjust the pH value of the sample solution. The SHLLME procedure was optimized by univariate analysis and the Box-Behnken response surface methodology . Optimum conditions were as follows: 105 mg of sodium decanoate , 246 mg of [Emim][HSO 4 ], 131 mg of sodium fluoroborate amount, and 128 mg of sodium carbonate. Under optimized conditions, the extraction recovery varied from 77.0% to 97.2%, and relative standard deviations varied from 0.5% to 4.5%. The limits of detection were 0.6 μg L −1 and 0.006 μg L −1 for pyrethroids and cadmium, respectively. This established method has the potential to continuously extract compounds with different physical and chemical properties.
研究领域:
分析化学
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环境科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）