COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Zixuan Wang,Han Wang,Ziwei Wang,Danlian Huang,Hong Qin,Yangzhuo He,Ming Chen,Guangming Zeng,Piao Xu
In this study, the oxidative degradation of tetracycline (TC) by ferrocene-modified graphite phase carbon nitride (Fe/g-C 3 N 4 ) activated persulfate (PS) under light-assisted conditions is examined. The materials are characterized by a series of methods such as SEM, TEM , XRD , FTIR, XPS , etc. This article explores the influence of the amount of sulfate, the initial concentration of pollutants, the amount of catalyst, and the pH value on the reaction system. When the amount of PS added reaches 2.5 mM and the catalyst dosage is 1 g L −1 , the Fe/g-C 3 N 4 /PS/Vis exhibit the best performance for tetracycline removal. In 60 min, the removal of tetracycline reaches 93% under its natural pH. In the reaction system acidic neutral conditions are more conducive to degrade TC. The results show that the doping of ferrocene inhibits the recombination of electron-hole pairs in the g-C 3 N 4 , expands the light response range to speed up the removal rate of tetracycline. At the same time, iron cycle generated by ferrocene modification helps to activate persulfate to produce sulfate radicals with strong oxidizing properties. Sulfate radicals, hydroxyl radicals , superoxide radicals and holes are the main active species proved by ESR test and the quenching experiments. The synergy between photocatalysis and PS activation promotes the production of active species and the tetracycline removal. The results show that the Fe/g-C 3 N 4 composite material activated persulfate under visible light is an effective method to remove tetracycline from water.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED ORGANOMETALLIC CHEMISTRY
·
2017
·Vol. 32
·期 1
·e3932
·
IF 2.319
Weidong Zhou,Li Wang,Haojie Yu,Xia Xia
A series of ferrocene-modified poly(glycidyl methacrylate) (PGMA-Fc) compounds were synthesized and applied as burning rate catalysts in simulative solid propellant to overcome migration problems. 1 H NMR and Fourier transform infrared spectroscopies and gel permeation chromatography were used to characterize the synthesized polymers. Their electrochemical behavior was evaluated using cyclic voltammetry. Their catalytic performance for the decomposition of ammonium perchlorate (AP) was investigated using thermogravimetric analysis. Anti-migration studies were conducted in migration tubes under 50°C. The results show that PGMA-Fc has a good catalytic effect on lowering the thermal decomposition temperature of AP. Anti-migration studies show that PGMA-Fc has better anti-migration performance than ferrocene and catocene.
研究领域:
材料科学
·
催化化学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Min Tan,Jing Zeng,Fu-Zhong Zhang,Ye-Tao Zhang,Hongli Li,Shu-Ting Fan,Jia-Xin Wang,Minglong Yuan,Bang-Jing Li,Sheng Zhang
Slow healing of wounds induces great pain in diabetic patients. However, developing new approaches to promote diabetic wound healing is still one of the toughest challenges in the medical field. Here, we constructed a new double-layer hydrogel to effectively regulate reactive oxygen species (ROS) on the wound and promote diabetic wound healing. The inner layer contains glucose oxidase (Gox), ferrocene-modified quaternary ammonium chitosan (Fc-QCs), and poly(β-cyclodextrin) (Pβ-CD), which is used to generate hydroxyl radicals (•OH) for antibacterial in the early stage of wound healing and collapses gradually. The outer layer is composed of gelatin and dopamine. In the later stage of wound healing, the outer layer contacts the skin, which is beneficial for ROS clearance on the wound. Antibacterial, ROS scavenging, and wound healing experiments have shown that the double-layer hydrogel possesses two-stage ROS regulating properties for programmed diabetic wound healing. In conclusion, it will be one of the most potential dressings for treating diabetic wounds in the future.
研究领域:
材料科学
·
生物医学工程
·
伤口愈合
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Jia Kong,Shixuan Zhao,Xue Han,Wenxin Li,Jiaxing Zhang,Yuefei Wang,Xihui Shen,Yinqiang Xia,Zhonghong Li
Fluorescent proteins (FPs) provide a ratiometric readout for quantitative assessment of the destination of internalized biomolecules. FP-inspired peptide nanostructures that can compete with FPs in their capacity are the most preferred building blocks for the synthesis of fluorescent soft matter. However, realizing a ratiometric emission from a single peptide fluorophore remains exclusive since multicolor emission is a rare property in peptide nanostructures. Here, we describe a bioinspired peptidyl platform for ratiometric intracellular quantitation by employing a single ferrocene-modified histidine dipeptide. The intensiometric ratio of green to blue fluorescence correlates linearly with the concentration of the peptide by three orders of magnitude. The ratiometric fluorescence of the peptide is an assembly-induced emission originating from hydrogen bonds and aromatic interactions. Additionally, modular design enables ferrocene-modified histidine dipeptides to use as a general platform for the construction of intricate peptides that retain the ratiometric fluorescent properties. The ratiometric peptide technique promises flexibility in the design of a wide spectrum of stoichiometric biosensors for quantitatively understanding the trafficking and subcellular fate of biomolecules.
研究领域:
生物化学
·
纳米技术
·
分子生物学
·
生物物理学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Xiaoyu Xu,Zishan Zeng,Jie Chen,Binyao Huang,Zilin Guan,Yanjuan Huang,Zeqian Huang,Chunshun Zhao
Utilizing intratumoral iron mediated Fenton reaction to induce cancer cells destruction, chemodynamic therapy (CDT) is an emerging tumor-specific therapeutic strategy. However, the CDT efficacy is severely restrained by insufficient endogenous H 2 O 2 and catalytic ferrous ions in tumor site. Herein, based on innovative small molecule prodrug design concept, an acid-labile ferrocene-modified cinnamaldehyde prodrug (Fc-CA) was first synthesized. Skillfully combining ROS-generator CA with Fenton catalyst Fc in its molecular structure, Fc-CA could synchronously elevate H 2 O 2 level and catalytic iron amount for enhanced CDT efficacy. Then, hydrophobic Fc-CA was efficiently encapsulated into hydrophilic cyclodextrin-modified hyaluronic acid conjugate (HA-CD) via host-guest interactions, to spontaneously form pH/redox dual-responsive supramolecular catalytic nanoreactor (HA-CD/Fc-CA NPs). The nanoreactor with high drug loading and stability, excellent catalytic activity and tumor specificity could preferentially accumulate in tumor tissues via EPR effect and CD44 receptor-mediated internalization. Through the cleavage of acid-labile hydrazone bond under acidic lysosome environments, the nanoreactor would be dissociated and release pre-protected CA for reinforced oxidation therapy and amplified H 2 O 2 level, which would in turn react with Fc through cascaded Fenton reaction, to generate highly cytotoxic •OH for enhanced cancer killing in a positive feedback process. Both in vitro and in vivo results verified excellent cascade-amplifying therapeutic performance and favorable biocompatibility of this nanoreactor. This study provides an innovative strategy for exploiting versatile organic therapeutic nanoplatforms, simultaneously activating tumor-specific oxidative stress amplification and cascaded enhanced Fenton reaction for superior cancer therapy with excellent biosafety.
研究领域:
纳米技术
·
癌症治疗
·
化学生物学
·
材料科学
·
药学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）