One-pot preparation of 3-chloropiperidine compounds via Cu(II)-promoted intramolecular chloroamination of unfunctionalized olefins
3-Chloropiperidine compounds were obtained via Cu(II)-promoted one-pot intramolecular chloroamination of N -benzyl-4-penten-1-amines and subsequent rearrangement. The reaction conditions leading to this skeleton were studied, and the structure of the product was confirmed by NMR as well as X-ray diffraction experiments.
CAS / MDL:
10125-13-0
研究领域:
有机化学
·
药物化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）