Biomaterials Advances
·
2023
·
IF 0
Mengxing Ge,Deqiao Xie,Youwen Yang,Huixin Liang,Jiasen Gu,Qiuwei Zhang,Jianling Xie,Zongjun Tian
Recent advancements in medical technology and increased interdisciplinary research have facilitated the development of the field of medical engineering. Specifically, in bone repair, researchers and potential users have placed greater demands on orthopedic implants regarding their biocompatibility, degradation rates, antibacterial properties, and other aspects. In response, our team developed composite ceramic samples using degradable materials calcium phosphate and magnesium oxide through the vat photopolymerization (VP) technique. The calcium phosphate content in each sample was, respectively, 80 %, 60 %, 40 %, and 20 %. To explore the relationship between the biocompatibility, antibacterial activity, and MgO content of the samples, we cultured them with osteoblasts (MC3T3-E1), Escherichia coli (a gram-negative bacterium), and Staphylococcus aureus (a gram-positive bacterium). Our results demonstrate that as the MgO content of the sample increases, its biocompatibility improves but its antibacterial activity decreases. Regarding the composite material samples, the 20 % calcium phosphate content group exhibited the best biocompatibility. However, after 0.5 h of co-cultivation, the antibacterial rates of all groups except the 20 % calcium phosphate content group co-cultured with S. aureus exceed 80 %. Furthermore, after 3 h, the antibacterial rates against E. coli exceed 95 % in all groups. This is because higher levels of MgO correspond to lower pH values and Mg 2+ concentrations in the cell and bacterial culture solutions, which ultimately promote cell and bacterial proliferation. This elevates the biocompatibility of the samples, albeit at the expense of their antimicrobial efficacy. Thus, modulating the MgO content in the composite ceramic samples provides a strategy to develop gradient composite scaffolds for better control of their biocompatibility and antibacterial performance during different stages of bone regeneration.
研究领域:
生物医学工程
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材料科学
·
组织工程
✓ 已验证
产品关联
DOI
PubMed
OPTICS AND LASER TECHNOLOGY
·
2025
·
IF 5
Mengxing Ge,Maimaitijiang Mamuti,Deqiao Xie,Yun Ye,Youwen Yang,Huixin Liang,Yang Liu,Xinghai Ning,Zongjun Tian
In recent years, additive manufacturing of biodegradable composite ceramics has attracted widespread attention. This study explores the vat photopolymerization (VP) of Ca 3 (PO 4 ) 2 / MgO composite ceramics, investigating the VP slurry and the effects of material composition and light-curing parameters on the monolayer curing depth and excess curing width of the green body. When the curing parameters are consistent, the monolayer curing depth of the Ca 3 (PO 4 ) 2 group, composite group, and MgO group samples decreases successively. Whereas, the excess curing width sequentially increases. When the material is the same and the exposure energy is constant, the impact of exposure time on monolayer curing depth is higher than that of exposure intensity. Regarding excess curing width, the situation is completely reversed. This research serves as a reference for the development of composite ceramic slurries and the process of photopolymerization, providing theoretical guidance for controlling the precision of subsequent photopolymerization shaping.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
SOLAR ENERGY MATERIALS AND SOLAR CELLS
·
2022
·
IF 7.305
Jinpeng Lv,Xiangyu Wen
Passive thermal control coatings (TCC's) have been widely used to tune the thermal equilibrium of spacecraft surfaces since 1970s. Development of new TCC's with improved thermo-physical properties and radiation hardness are essential to the space assets that fly in harsh environments. Herein, we fabricated calcium orthophosphate based inorganic white paint, which possess relative low solar absorptance (α s ) of 0.095 and thermal emittance (ε H ) of 0.88. Noticeably, the Ca 3 (PO 4 ) 2 coating shows excellent space radiation tolerance and thermal control capacity. After performing 90 keV proton irradiation at a fluence of 4×10 15 cm -2 , the α s of ZnO coating increases from 0.160 to 0.213 while the Ca 3 (PO 4 ) 2 coating rises from 0.095 to 0112, which only degrades one third (0.017) of the ZnO coating (0.053). Furthermore, after performing simulated solar irradiation test, the surface temperature of Ca 3 (PO 4 ) 2 paint is 14.4 °C lower than that of ZnO coating, evidencing its prominent thermal-optical performance. Besides, we also found that Ga 2 O 3 based liquid-glass white paint is a good candidate for thermal equilibrium of spacecraft.
研究领域:
材料科学
·
航天工程
✓ 已验证
DOI
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2024
·Vol. 107
·期 6
·4242-4251
·
IF 3.5
Shuya Wang,Wenzhi Sun,Tingting Zhao,Chunqing Fu,Xiaoyan Fu,Hongwu Zhang
In this paper, X-ray-activated super long persistent ultraviolet A luminescence from Ca 3 (PO 4 ) 2 : Ce 3+ has been observed. The crystal structure analysis has shown that the as-prepared samples are pure β-Ca 3 (PO 4 ) 2 phases with rhombohedral structure and R 3 c space group. The photoluminescent spectra of the samples all consist of a broad band in 340–400 nm UVA1 region, which is assigned to the 5d 1 –4f 1 electronic transition of Ce 3+ ions. More important, under the 3 min X-ray irradiation, Ca 3 (PO 4 ) 2 : Ce 3+ show super long persistent luminescence in the UVA1 region, which can persist for more than 16 h. And its afterglow intensity after 16 h decay is still 4.10 times stronger of the back ground intensity. Furthermore, only 10 s X-ray irradiation can induce excellent long persistent UVA luminescence of Ca 3 (PO 4 ) 2 : 0.08Ce 3+ , which can persist for more than 5 h and afterglow emission intensity is about 3.03 times of the background intensity. The trap analysis has confirmed that the different X-ray irradiation time do not create new traps and there is the same trap with 0.75 eV trap depth existing even under the extremely low X-ray dose (10 s X-ray irradiation). Furthermore, under 10 s X-ray irradiation, the thermoluminescence (TL) intensity of Ca 3 (PO 4 ) 2 : 0.08Ce 3+ still reaches 0.32 times of the initial TL intensity even after 120 min, which thus leads to the super long persistent luminescence. Thus, the large amounts of trapped electrons induced by the high energy X-ray irradiation are the principal cause for super long persistent UVA luminescence of Ca 3 (PO 4 ) 2 : Ce 3+ .
研究领域:
材料科学
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发光材料
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光学物理
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辐射探测
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荧光粉研究
✓ 已验证
DOI
高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 3.475
Conghai Li,Juan Zhao,Zhijin Zhang,Yanjun Jiang,Muhammad Bilal,Yunhong Jiang,Shiru Jia,Jiandong Cui
Lipase-inorganic hybrid nanoflowers were prepared using Ca 3 (PO 4 ) 2 as the inorganic component and lipase from Aspergillus oryzae ( A. oryzae ) as the organic component. The influences of metal ions with different valence, various additives (surfactant), and synthesis conditions on the activity of the lipase hybrid nanoflowers were systematically investigated. Results revealed that the valence state of metal ions played an important role on the shape and activity of lipase hybrid nanoflowers. The synthesized lipase hybrid nanoflowers using bivalence metal ions (Ca 2+ , Mn 2+ , and Zn 2+ ) as the inorganic components exhibited relative high activity. However, very low activities were observed in the lipase hybrid nanoflowers using univalent metal ions (Ag + ) or trivalent metal ions (Al 3+ , Fe 3+ ). More importantly, Ca 2+ not only induced self-assemble of lipase hybrid nanoflowers, but also activated the enzyme activity by inducing conformational changes in lipase from A. oryzae . As a result, lipase/Ca 3 (PO 4 ) 2 hybrid nanoflowers (hNF-lipase) exhibited the high activity. The hNF-lipase displayed 9, 12, and 61 folds higher activity than lipase/Ag 3 PO 4 hybrid nanoflowers, lipase/AlPO 4 hybrid nanoflowers, and lipase/FePO 4 nanoflowers, respectively. Compared with free lipase, the hNF-lipase displayed 172 % increase in activities by using 0.15 mM Tween-80 as an activity inducer (activated hNF-lipase). Furthermore, the hNF-lipase and activated hNF-lipase exhibited increased stability against high temperature and denaturant, and had good storage stability and reusability.
研究领域:
生物化学
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纳米技术
·
酶学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 52
·期 1
·547-558
·
IF 2.047
Zhou Jian,Ren Sili
The phosphor-converted white light-emitting diode (WLED) has received tremendous attention as a promising alternative to traditional light sources in lighting and displays. Herein, a novel broadband red emitter Ca 2 Sr(PO 4 ) 2 :Mn 2+ was successfully designed and synthesized based on the Sr-alloying and Mn-doping of Ca 3 (PO 4 ) 2 . The phase purity of the materials was verified by x-ray diffraction (XRD) analyses, while a scanning electron microscope (SEM) coupled with an energy-dispersive spectrometer (EDS) was employed to confirm the uniform dopant distribution. XRD Rietveld refinements were further performed to clarify the site occupation of alloying Sr and the Mn dopants. Effective site engineering confined the Mn dopants in a highly symmetric Ca5 site and excluded the immersion of Sr, leading to an extraordinarily long fluorescence lifetime. Density functional theory (DFT) simulations also revealed the good potential of the materials as host matrices for activators such as Mn 2+ . Finally, Ca 2 Sr(PO 4 ) 2 :Mn 2+ was used to fabricate a WLED prototype based on a near-ultraviolet (n-UV) commercial LED chip, which realized a warm white-light emission and high color rendering index (Ra) of 82.9. This WLED was able to survive the long-term stability test while maintaining high luminous efficacy of ~ 60 lm/W within 20 h, showing its great potential in practical applications.
研究领域:
材料科学
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光电技术
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照明技术
·
固体物理
✓ 已验证
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2022
·
IF 4.598
Xin Xie,Lei Sheng,Rong Xu,Xingxu Gao,Ling Yang,Yong Gao,Yaozong Bai,Gaojun Liu,Haoyu Dong,Xiaoli Fan,Tao Wang,Xianli Huang,Jianping He
The organic–inorganic composite separator possesses great thermal stability and electrolyte wettability, which is normally prepared via the slurry containing binder. However, this preparation is involved with large amounts of organic solvent that is harmful to health. In this paper, we design a novel method that combines the crosslinking technology and biomimetic mineralization process to prepare a Ca 3 (PO 4 ) 2 inorganic coating modified polyethylene separator (CaP@PE). The obtained composite separator exhibits stronger affinity to electrolyte, and its porous coating structure can store more liquid electrolyte, thus the ionic conductivity is promoted from 0.27 mS cm −1 to 0.52 mS cm −1 and the lithium-ion transference number is increased from 0.26 to 0.36. Compared with PE separator, CaP@PE separator shows better thermal stability at high temperature. Due to the improved ionic transport performance and reduced charge transfer impedance, LiCoO 2 /Li half-cell employing CaP@PE separator displays superior cycle stability and capacity retention ability after 150 cycles at a current density of 1C. Even at a high rate of 5C (7.5 mA cm −2 ), the cell with CaP@PE separator still exhibits a discharge capacity of 0.80 mAh. This work provides a promising separator to optimize the electrochemical performance and safety performance in lithium-ion battery.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2025
·
IF 3.8
Fulong Hao,Tongshu Zhang,Xinyi Zhang,Yuheng Zhang,Wanyu Zhao,Zehua Xue,Xiyuan Zhang,Zuobin Tang
Rare-earth-doped β-Ca 3 (PO 4 ) 2 -type derivatives are a research hotspot in optoelectronics materials, yet achieving eye-friendly comfortable emission in such multication lattice systems remains a challenge. Herein, a novel orange-emitting phosphor Sr 7 LuNaMg 1.5 (PO 4 ) 7 :Eu 2+ was designed based on the crystal structure of Sr 9 Fe 1.5 (PO 4 ) 7 (ICSD No. 93870), whose structure is topologically similar to β-Ca 3 (PO 4 ) 2 . The title phosphor exhibits ultra-broadband emission centered at 599 nm (full-width at half-maximum = 197 nm) under 395 nm n-UV excitation. Structural characterization coupled with spectroscopic studies demonstrates the coexistence of multiple luminescent centers in Sr 7 LuNaMg 1.5 (PO 4 ) 7 :Eu 2+ . A progressive redshift in the emission color coordinates was observed with increasing Eu 2+ doping concentrations, attributable to selective cation occupancy and crystal field effects. The concentration-dependent quenching mechanism was elucidated through comprehensive analysis based on Dexter's theory. Characterization of quantum efficiency, thermal stability and packing density validated the suitability of Sr 7 LuNaMg 1.5 (PO 4 ) 7 :Eu 2+ phosphor for high-performance white light-emitting diodes, demonstrating it as a competitive luminescent material for advanced lighting technologies.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Research and Technology-JMR&T
·
2023
·
IF 6.4
Mengxing Ge,Deqiao Xie,Youwen Yang,Huixin Liang,Chen Jiao,Yun Ye,Junnan Wu,Hanjiao Yu,Zongjun Tian
Biodegradable bone grafts have gained considerable attention in the field of clinical research as they can be used to avoid re-surgery to remove scaffolds. We fabricated biodegradable composite ceramic scaffolds using magnesium oxide and calcium phosphate following the vat photopolymerization technology. We studied the effects of different magnesium oxide content on the process of in vitro degradation of the composite scaffolds and discussed the degradation process by comparing the extent of degradation realized in Tris-HCl buffer and simulated body fluids. We also explored the variations in the mechanical properties of the scaffolds during degradation. The results revealed that the composite scaffolds maintained the strength standard for spongy bone (compressive strength σ: 2–20 MPa) even after 28 d of degradation. Additionally, the strength of the composite scaffold containing 80 wt% magnesium oxide was comparable to the strength standard recommended for cortical bones (σ: 100–200 MPa). Controllable degradation rates were recorded, and acceptable mechanical properties were observed for these scaffolds during degradation. The results reported herein can be potentially used to expand the application prospects of biodegradable scaffolds.
研究领域:
生物材料学
·
医学工程
·
组织工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2020
·
IF 5.278
Anming Wang,Xinxin Chen,Jianyun Yu,Ningning Li,Huimin Li,Youcheng Yin,Tian Xie,Stephen Gang Wu
To prepare enzyme@Ca 3 (PO 4 ) 2 for environmentally friendly biocatalysis, Ca 2+ and (PO 4 ) 3− were extracted from bone waste by acidification. In the nearly neutralized filtrate, the Ca 2+ and (PO 4 ) 3− formed a Ca 3 (PO 4 ) 2 sediment that crystallized on a template of Thermomyces lanuginosus lipase (TLL) at 4 ℃ for 24 h, producing enzyme@Ca 3 (PO 4 ) 2 -Bone hybrid nanoflowers (hNFs). Clindamycin palmitate was efficiently synthesized by transfer of a palmityl moiety from vinyl palmitate to clindamycin free base using these hNFs as a biocatalyst. At 30 ℃ in petroleum ether (PE) as the solvent, the yield of the TLL hNF-catalyzed reaction was as high as 70.0%. Even at a high temperature (80 ℃), the yield in the hNF-catalyzed reaction was still 52.6%, but no product was detected when using free lipase as the catalyst. Moreover, the hNFs retained 90% of their initial activity after 10 cycles (120 h, 12 h per cycle). This green and sustainable method that utilizes bone waste from food production as the raw source of the inorganic component was facile and efficient, and the system may also be applicable for preparing other enzyme@Ca 3 (PO 4 ) 2 hNFs for industrial applications.
研究领域:
生物化学
·
环境科学
·
制药工程
✓ 已验证
DOI
高影响因子
Inorganic Chemistry Frontiers
·
2019
·Vol. 6
·期 10
·2837-2849
·
IF 5.934
Peipei Dang,Dongjie Liu,Guogang Li,Sisi Liang,Hongzhou Lian,Mengmeng Shang,Jun Lin
Recently, controllable photoluminescence tuning by devising a solid solution framework, adjusting the valence mixing of Eu2+/Eu3+ and designing efficient energy transfer between activator ions has been extensively investigated and reported due to its significant advantages in the improvement and regulation of the luminescence performances of white light-emitting diodes (W-LEDs). In this study, we designed a series of novel Eu2+-doped (1 − x)Ca3(PO4)2–xCa9Y(PO4)7 (x = 0–1.0) isostructural solid solution phosphors with a β-Ca3(PO4)2-type structure, and powder samples were prepared via the traditional high-temperature solid-state reaction process. The crystal field variation around the Eu2+ ions causes superposition of linear luminescence and induces optical property tuning with a change in the solid solution ratio, x, values. Besides the high-energy emission peak at 418 nm in Ca3(PO4)2:0.03Eu2+, another low-energy emission peak at 486 nm was observed with the formation of the solid solution. Moreover, the corresponding high-energy emission peaks shifted from 418 to 430 nm, and the luminescence intensity of the low-energy emission at 486 nm increased with an increase in x, which was attributed to the combined effect of crystal field splitting of the local lattice and superposition of linear luminescence. In addition, tunable emission across the whole white light region could be realized by constructing a solid solution and adjusting the overall Eu concentration in (1 − x)Ca3(PO4)2–xCa9Y(PO4)7:Eu (x = 0.5, 0.7, 0.9, and 1.0), and the corresponding luminescence mechanisms have been proposed and discussed in detail. In the pursuit of precise color tuning, we also tested the Eu2+ → Mn2+ energy transfer in different compositions (x = 0.2, 0.5, 0.7, and 0.9) of the solid solution phosphors, and successive emission tuning from the blue and cyan range and then the red range was successfully achieved. Finally, the temperature-dependent photoluminescence and decay time were revealed systematically, and the corresponding mechanisms for the thermal quenching behavior have been discussed. This study provides a new perspective for color tuning originating from the simultaneous isostructural solid solution, valence mixing of Eu2+/Eu3+ and efficient energy transfer.
研究领域:
材料科学
·
光学材料
·
无机化学
·
固体物理
·
发光学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）