TALANTA
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2024
·
IF 5.6
Yujie Guo,Lingfei Li,Shihao Xu,Maofeng Zhang,Changlong Jiang
Rapid monitoring of trace antibiotics in the field in real time is essential for environment forewarning and human health. High sensitivity and real-time on-site quantitative monitoring of antibiotic residues can be accomplished by integrating portable sensors alongside fluorescent optics to construct an intelligent sensing platform that smoothly eliminates the instability of conventional detection methods. In this study, a ratiometric fluorescence sensor for the ultrasensitive detection of pefloxacin was built employing the photoinduced electron transfer (PET) mechanism from red Eu-MOFs to Mn 2+ -PEF complex. A visual color change results from the photoinduced electron transfer process from manganese ions to pefloxacin weakening the ligand metal charge transfer (LMCT) process in Eu-MOFs. This enables the ultrafast visible detection of pefloxacin and produces a transient shift in visual color with a detection limit as low as 15.4 nM. For the detection of pefloxacin in water, tomato, and raw pork samples, various sensing devices based on the developed fluorescent probes exhibit good practicability and accuracy. With the development of the ratiometric fluorescence sensing probe, it is now possible to quickly and quantitatively identify pefloxacin residues in the environment, offering a new method for ensuring the safety of food and people's health.
研究领域:
环境科学
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分析化学
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生物医学工程
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Biosensors-Basel
·
2025
·Vol. 15
·期 5
·313
·
IF 5.6
Yinjun Li,Hua Ding,Ziyu Wang,Zewei Luo,Xitian Peng
Lateral flow immunoassay (LFIA) is a promising tool for rapid detection in the field of agricultural product analysis due to its advantages of cost-effectiveness and operational simplicity. In this work, Eu metal–organic frameworks (MOFs) were introduced to LFIA as a rapid detection method characterized by high stability and low interference. Key research objectives included strong fluorescence, ease of labeling, and the utilization of fluorescent probes. Eu-MOFs were synthesized in one step via the hydrothermal method, exhibiting a fluorescence lifetime of 163 μs and spherical particles with diameters ranging from 250 to 400 nm. These conditions fulfill the characteristics and requirements of LFIA. Eu-MOFs exploit the porous nature of MOFs to mitigate the drawbacks associated with complex crosslinking agents. This enables antibody proteins to be cross-linked merely upon contact, thereby simplifying the detection process. A time-resolved LFIA method was developed utilizing Eu-MOFs for the detection of aflatoxin B1 (AFB1) in corn, achieving a limit of detection (LOD, IC10) of 0.149 ng/mL. The accuracy and reliability of the Eu-MOFs-LFIA method were validated through comparisons with spiked concentrations during spiking and blind sample analyses, with verification conducted using ultra-high-performance liquid chromatography mass spectrometry (UPLC-MS). Furthermore, testing of real samples demonstrated that the Eu-MOFs-LFIA method can effectively facilitate rapid detection of AFB1 in corn.
研究领域:
食品科学
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分析化学
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生物技术
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MICROCHEMICAL JOURNAL
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2025
·
IF 5.1
Yingchun Gao,Yanmei Chen,Zhiyuan Li,Qi Lu,Yunyun Chen,Yangyang Jiang,Xiaoya Fang,Lei Song,Xiaoxia Mao
Antibiotic contamination is increasing and poses a major threat to the ecosystem. The development of effective and low-cost methods for the in-situ detection of ciprofloxacin (CIP) in environmental samples has become an important research hotspot. Here, we develop a smartphone-compatible visualization kit oriented for CIP detection based on metal–organic frameworks Eu-MOFs@hydrogel composites,which exhibits efficient and specific recognition of CIP and results in a change in fluorescence color from red to light blue. Besides, the concentration of CIP can be determined by RGB analysis on a smartphone with a wide linear range (0.002–50 μM) and a low detection limit (0.00137 μM). The assay kit also possesses good environmental adaptability and stability, showing excellent selectivity and anti-interference ability for 11 common veterinary drugs. Additionally, the recoveries of the sensing probe in chicken and duck manure samples ranged from 70.66 % to 112.2 % with the relative standard deviations (RSDs) within 1.88 %-5.53 %. These results indicate that the developed hydrogel portable smart detection kit has great potential for practical field testing of CIP.
研究领域:
环境科学
·
生物分析化学
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Materials Today Chemistry
·
2024
·
IF 6.7
Jian Gou,Yousong Hu,Luxin Xing,Jun Xu,Fengzhi Yue,Lina Zhang,Lei Jia
Traditional luminescent materials for anti-counterfeiting usually adopt encryption of low-level systems with limited security, which seriously hinders their application in preventing counterfeiting and information leakage. Therefore, it is urgent to develop materials for higher-level anti-counterfeiting. In this work, a stimulus-responsive intelligent luminescent material (AC@CDs-Eu-MOFs) was prepared by co-loading green-fluorescence CDs and red-fluorescence Eu-MOFs on Amino clay (AC). 5D security barcodes, which were easy to observe while difficult to clone, were ulteriorly designed based on the nanocomposite owing to the tunable fluorescence by optical stimulation and chemical stimulus. Owing to the large capacity, low cost, and easy authentication, the 5D security barcodes possess enormous potential in optical data storage and multi-dimensional information encryption. In addition, the chemical stimulus-response enables the nanocomposite achievable in detection of Cu 2+ and Bacillus anthracis. Particularly, quantitative determination of copper in environmental water samples could be realized with a detection limit as low as 10.67 nM. Therefore, the material shows potential for detection of environmental pollutants besides advanced anti-counterfeiting.
研究领域:
材料科学
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纳米技术
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环境科学
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生物技术
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光学
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Qingxiang Liu,Xuelian Hu,Xiaoxiao Dong,Peng Liu,Ning Zhang,Zhe Gao,Wenxiu Wang,Huiling Li,Shuo Wang,Xiuying Liu,Yiwei Tang
A high-performance fluorescent “turn-on” aptasensor (Eu-MOFs@SMZ-Apt) for sulfamethazine (SMZ) determination was designed using dual-emitting europium metal-organic frameworks (Eu-MOFs) as a signal transducer and an amplifier. Eu-MOFs featuring dual emission peaks (430 nm and 620 nm) were first prepared via a facile self-assembly strategy employing Eu (III) ions and 2-aminoterephthalic acid as precursors. The high-affinity aptamer was bonded with Eu-MOFs to form Eu-MOFs@SMZ-Apt through the amidation reaction. Benefiting from the integration of inherent virtues from Eu-MOFs and aptamer, the Eu-MOFs@SMZ-Apt-based sensor allowed sensitive and selective determination of SMZ with good linear relationships in a range of 1.4–40 ng mL −1 and a low detection line (0.379 ng mL −1 ). This sensor was successfully applied to the determination of trace SMZ in real samples with satisfactory recoveries (86.47–113.52%) and a relative standard deviation (<6.51). Consequently, the Eu-MOFs@SMZ-Apt ratiometric fluorescence sensor furnishes new possibilities for the accurate detection of various pollutants in food.
研究领域:
分析化学
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食品科学
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生物传感
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.8
Yourong Zhao,Yuhong Xie,Yiying Wang,Xin Jiang,Hongda Li,Daojiang Gao,Zhanglei Ning
Aniline, a toxic volatile organic compound, presents considerable risks to human health and environmental safety. In this study, we have developed a novel composite fluorescent probe, named as CPB@Eu-MOFs, fabricated through the integration of perovskite quantum dots (CPB) into a europium-based metal-organic frameworks (Eu-MOFs). This composite serves as a self-calibrating, ratiometric fluorescent probe for the detection of aniline. It exhibits high selectivity towards aniline over common interfering volatile organic compounds, as well as a high sensitivity with a detection limit of 4.72 × 10 −6 M and a wide linear response range from 5 × 10 −4 to 10 −1 M. A distinct photoluminescence color evolution from red to orange, yellow, green and finally blue is observed with increasing aniline concentration, enabling rapid visual quantification alongside instrumental analysis. This work proposes a convenient and reliable dual-mode sensing strategy, combining visual and ratiometric fluorescence readouts, for monitoring aniline in environmental and industrial safety applications.
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DYES AND PIGMENTS
·
2025
·
IF 4.2
Di Wu,Chengpei Du,Lingyan Ma,Rui Xiao,Long Tan,Wenjing Qi
Owing to Zn 2+ -sensitized fluorescent effect, boric acid functionalized zinc-europium binuclear metal-organic frameworks ( Zn-Eu-MOFs ) are synthesized and applied in fluorescent quenching detection of luteolin in Chrysanthemum tea for the first time. Eu 3+ /Zn 2+ and 5-boronobenzene-1,3-dicarboxylic acid (BBDC) are utilized via a fast one-pot microwave process at 120 °C for 1 h. Due to energy transfer efficiency change by “antenna” effect and better effective energy transfer of Zn 2+ than Eu 3+ , Zn 2+ increases fluorescence of Zn-Eu-MOFs nearly 3.5 times. Different ligands and different metal ions are compared to synthesize Zn-Eu-MOFs . Highly specific binding affinity of boric acid towards cis-diol structure in luteolin and chelating of Zn 2+ with luteolin achieves fluorescent quenching detection of luteolin with low limit of detection of 16 nΜ and high selectivity. When it is utilized in fluorescent detection of luteolin in water and Chrysanthemum tea, mean recoveries are obtained from 99.5 % to 102.7 % and from 99.3 % to 100.6 %, respectively.
研究领域:
化学
·
食品科学
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122439
·
IF 7.5
Yourong Zhao,Yuhong Xie,Yiying Wang,Hongda Li,Daojiang Gao,Zhanglei Ning
Excessive levels of phosphate ions (PO 4 3- ) pose serious risks to human health and environmental ecosystems. In this work, a ratiometric fluorescent probe, G-CDs@Eu-MOFs composite, was designed and synthesized via a post-synthetic modification strategy. The composite was employed for selective detection of phosphate ions. The resulting probe displays two well-resolved fluorescence emission peaks at 419 nm and 616 nm, which exhibits distinct responses to phosphate ions, thereby providing an intrinsic self-calibration capability. Upon interaction with PO 4 3- , the probe demonstrates a strong linear response (I 419 /I 616 ) over the concentration range of 10 −4 M to 4.5 × 10 −3 M, with a high correlation coefficient (R 2 = 0.9986). The detection limit (LOD) is determined to be 0.927 μM. A clear fluorescence color shift from blue-red to blue allows for rapid visual identification of phosphate. Furthermore, by integrating the probe with a smartphone-based platform, a user-friendly, accurate, and portable approach is established for on-site and real-time monitoring of phosphate. This strategy shows considerable promise for environmental and biomedical applications.
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INORGANIC CHEMISTRY COMMUNICATIONS
·
2023
·
IF 3.8
Xinlin Wang,Rudong Zhu,Xiangkui Wang,Fengjiao Liu,Yan Gao,Rongfeng Guan,Yalei Chen
In this paper, the application of metal organic frameworks (MOFs) doped with carbon dots in fluorescence detection was studied.CDs@Eu-MOF/PVDF thin films were prepared by simple solvothermal method, carbon dots modification and in-situ growth process.The structure and morphology of the film was characterized by XRD, SEM, FT-IR and XPS.The results show that CDs@Eu-MOFs membrane has strong red fluorescence, good stability in methanol solvent, and high selectivity and sensitivity to nitrobenzene and 4-nitrophenol.The CDs@Eu-MOFs/PVDF film material can be used to detect nitrobenzene and 4-nitrophenol in methanol solvent and gaseous state. The detection limits of nitrobenzene and 4-nitrophenol in liquid are 0.2807 mg/L and 0.0168 mg/L, and the detection limits of nitrobenzene and 4-nitrophenol in gaseous state are 0.346 mg/L and 0.0136 mg/L.
研究领域:
材料科学
·
分析化学
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Shuang Liu,Chenxi Zhao,Huiya Yuan,Lina Gao,Yan Zhang
Rapid and accurate field testing for oxytetracycline (OTC) is crucial for ensuring food safety and monitoring environmental pollution. Herein, we report the construction of an aggregation-induced emission metal-organic frameworks (MOFs)-mediated molecularly imprinted ratio metric fluorescent sensor (AIE/Eu@MIPs) for the rapid and selective detection of OTC with high sensitivity. AIE MOFs with ultra-high quantum yield were utilized as the blue fluorescence emission carriers, thus avoiding any compromise between convenience and cost-effectiveness. The detection sensitivity was significantly enhanced by modifying the fluorescence signals, driven by the combined effects of the inner filter effect (IFE) and antenna effect (AE). The detection limit was as low as 21 nM (about 9.67 μg/kg). More importantly, a portable optical sensing platform integrating AIE/Eu@MIPs was developed for visual detection of OTC. The developed probe and portable device-based sensing platform demonstrate considerable potential for on-site detection of OTC in real-world applications.
研究领域:
食品安全
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环境监测
·
分析化学
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JOURNAL OF FLUORESCENCE
·
2026
·
IF 3.4
Liang Tianmi,Liu Shijian,Ma Wenjin,Tao Xiaoqi
Colla Corii Asini ( CCA ), a traditional food-medicine product, is vulnerable to food safety and market integrity due to frequent adulteration. This study developed a lateral flow assay based on polyethylenimine-functionalized europium metal-organic frameworks (PEI-Eu-MOFs-LFA) for quantitatively detecting donkey DNA to assess the authenticity of CCA , without the need for knowing the types of adulterants. The protonated amino groups on the PEI‑Eu-MOFs surface formed stable complexes with negatively charged single‑stranded DNA (ssDNA) probes. Electrostatic attraction and hydrogen bonding facilitated conjugate formation, leading to fluorescence quenching of the PEI-Eu-MOFs via the inner-filter effect (IFE). This method enables direct analysis after DNA extraction, eliminating the need for additional nucleic acid amplification steps, and completes the entire process in just 60 min. Furthermore, a calibration curve was established between the T/C ratio and the logarithmic value of donkey hide content (2% to 100%). The PEI-Eu-MOFs-LFA exhibited excellent sensitivity and accuracy, with a detection limit of 1.86%, recoveries ranging from 85.70% to 114.63%, and relative standard deviations from 2.48% to 12.59%. Consequently, PEI-Eu-MOFs-LFA demonstrates high sensitivity and accuracy, significantly improving detection efficiency and providing an innovative approach for quality control and market regulation of CCA .
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