SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Sijia Xie,Qiyu Lei,Linyu Zeng,Hai Xiong
An efficient mimic peroxidase platform of Fe-CDs/GOx based on the hybrid cascade system to produce in-situ H 2 O 2 for the visualized detection of glucose has been also developed in our group. Herein, the [Fe-CDs + H 2 O 2 + TMB] system was further performed to detect the biothiols (GSH, Cys, and Hcy) as representatives of the –SH group. The result exhibits that the higher concentration of biothiols can cause the absorbance signal at 652 nm to decrease, and the deep-blue color of oxTMB turns green until it is faded in 20 min by the naked eye. The colorimetric method showed the LOD are 0.54, 0.29, and 1.41 μM for GSH, Cys, and Hcy respectively, without interference in the presence of other amino acids. The smartphone-based and paper-based determination display good respect for biothiols in human serum or GSH in red wine. These simple and convenient strategies provide potential applications in the fields of clinical diagnosis and foods.
研究领域:
生物化学
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医学诊断
·
食品科学
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DOI
PubMed
高影响因子
OPTICAL MATERIALS
·
2021
·
IF 3.08
Xuyang Li,Zongxue Yu,Liangyan Shao,Xiaofang Feng,Haojie Zeng,Yuchuan Liu,Runxuan Long,Ximei Zhu
In order to effectively solve the two major problems of photocatalyst recovery and membrane fouling , this research combines photocatalyst and membrane separation technology . In this study, the NH 2 -MIL-88B(Fe)/CDs@GO material with good photocatalytic properties was synthesized by hydrothermal method and mechanical stirring, and the photocatalytic membrane was obtained by vacuum filtration. The results show that the NH 2 -MIL-88B(Fe)/CDs@GO membrane can effectively intercept and degrade methylene blue (MB). After 10 cycles, the rejection rate of MB can still reach 99.5%, which is about 2.5 times of pure GO membrane (40%). After 15 min of visible light irradiation, the Flux recovery rate (FRR) of NH 2 -MIL-88B(Fe)/CDs@GO membrane can reach 95%, and the antifouling performance is excellent. In this study, the composite photocatalytic membrane shows excellent stability, photocatalytic performance and self-cleaning property, which is conducive to widening the application prospect of wastewater treatment .
研究领域:
环境科学
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材料科学
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DOI
高影响因子
Inorganics
·
2026
·Vol. 14
·期 3
·88
·
IF 3.4
Naifeng Chen,Yi Li,Chenxia Gao,Chao Xue,Shuang Liu,Jinghang Li,Xi Cao,Kuilin Lv,Yuguang Lv
This study systematically investigated the characterization of 2Fe-CDs/12Mn-CeO2composites and the colorimetric sensing properties of H2O2, glucose (Glu), and glutathione (GSH). The morphology, structure, and optical properties of the 2Fe-CDs/12Mn-CeO2composite were analyzed in detail by XRD, FT-IR, SEM, TEM, XPS, and Raman spectroscopy, and its formation was supported by multiple complementary characterization techniques. The catalytic efficiency (kcat/Km) of the nanozyme is 152-fold higher than natural HRP under optimal conditions and remains 59-fold higher even after temperature normalization to 25 °C. In the colorimetric sensing experiments, the detection limits of Fe-CDs/Mn-CeO2were 0.21 μM, 2.7 μM, and 0.63 μM for H2O2, Glu, and GSH, respectively. Rapid and accurate determination of the concentrations of these biomolecules can be achieved by observing the color changes after Fe-CDs/Mn-CeO2reaction with the objects to be measured. The experimental results show that Fe-CDs/Mn-CeO2have high sensitivity and selectivity for H2O2, Glu, and GSH, which provides a solid theoretical and experimental basis for the application of Fe-CDs/Mn-CeO2in the field of biosensing and medical diagnosis.
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高影响因子
JOURNAL OF FLUORESCENCE
·
2026
·
IF 3.4
Gu Jianlong,Gao Li,Cai Jieyun,Liu Yuchen,Meng Hongming,Long Jie,Ma Jing,Yang Bing,Wang Chunqiong,Yang Yaling
Carbon dots-based nanozymes show great potential for chemiluminescence (CL) detection due to their stability, excellent catalytic properties, good biocompatibility, and facile synthesis. In this study, bimetallic carbon dot nanoenzymes (Cur/Cu, Fe@CDs) that promote the chemiluminescence signal of luminol were synthesized. Cur/Cu, Fe@CDs possess high peroxidase (POD) activity and can catalyze the luminol/hydrogen peroxide reaction to generate a strong chemiluminescence intensity, which is approximately 8.98 times higher than the chemiluminescence spectral signal produced by the same concentration of K 3 [Fe(CN) 6 ]. Additionally, a sensitive and rapid method for detecting magnesium ions (Mg 2+ ) was developed by leveraging the enhancing effect of Mg 2+ on the CL signal in this system. The proposed CL technique for Mg 2+ demonstrated a linear response range from 3.33 to 166.67 µM and a detection limit of 0.99 µM. Moreover, the method was successfully applied to analyze Mg 2+ in cigarette paper samples through a spiking procedure, achieving a recovery rate of 91.1% to 109.0%. This research offers substantial evidence supporting the advancement of efficient and sensitive platforms for Mg 2+ CL detection.
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PubMed
高影响因子
JOURNAL OF FLUORESCENCE
·
2026
·
IF 3.4
Hou Huijing,Luo Mingming,Li Fang,Tan Yijun,Liu Ruowei,Xu Longping,Feng Yanwen,Guo Xiangli,Wu Zijian
Kanamycin (KANA) is a veterinary drug residue that is highly scrutinized in food safety testing. In this study, a metal-organic framework-based aptamer-nanoenzyme (NH 2 -MIL-88B(Fe)/CDs-Apt) was introduced for the dual-mode detection of KANA. NH 2 -MIL-88B(Fe) catalyzes the oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) by H₂O₂ to form blue ox-TMB, thereby enabling colorimetric detection. As a fluorescence quencher, NH 2 -MIL-88B(Fe) quenches the fluorescence of CDs via photogenerated electron transfer (PET) or fluorescence resonance energy transfer (FRET) mechanisms. The detection limits were 0.716 fM (fluorescent) and 0.709 fM (colorimetric), respectively. The proposed aptasensor was successfully applied to the detection of KANA in eggs, honey, and lake water. This aptasensor demonstrates high sensitivity and accuracy, as well as broad application potential.
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高影响因子
Journal of Materials Chemistry B
·
2023
·Vol. 11
·期 25
·5898-5909
·
IF 7
Mei Yang,Jun Yao,Borui Su,Nini Xin,Ting Zhou,Mingze Zeng,Chengheng Wu,Dan Wei,Jing Sun,Hongsong Fan
As nanozymes, carbon dots (CDs) have attracted increasing attention due to their remarkable properties. Besides general enzyme activity, their photoluminescence and photothermal properties have been explored rarely, whereas their synergistic effects might produce CDs-based nanozymes of high performance. Here, iron-doped CDs (Fe-CDs) with tunable fluorescence and enhanced peroxidase-like activity were designed to develop a novel “three-in-one” multifunctional platform to provide dual-mode/dual-target detection and near infrared (NIR)-assisted antibacterial ability. This proposed strategy for a H2O2 test exhibited a wide linear relationship with a low limit of detection (LOD) of 0.16 μM (colorimetric) and 0.14 μM (ratiometric fluorescent). Furthermore, due to the nature of cholesterol being oxidized to H2O2 by cholesterol oxidase, sensitive and selective detection of cholesterol was realized, and the LOD was 0.42 μM (colorimetric) and 0.27 μM (ratiometric fluorescent), surpassing that reported previously. This result suggested that Fe-CDs could be used for dual-mode quantification of large family of H2O2-producing metabolites, thereby paving the way for developing multi-mode sensing strategies based on nanozymes. Moreover, this platform showed synergistic effects for antibacterial application, indicating great prospects for bacterial killing as well as wound disinfection and healing. Hence, this platform could contribute to the construction of multifunctional CDs with high performance.
研究领域:
生物医学工程
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分析化学
·
纳米技术
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Zongbo Zhang,Shiliang Song,Yan Ding,Jianhai Yu,Wenting Wu,Jin Li,Xin Wang,Yong Guo,Liang Gong
The precise and controllable preparation of carbon nanomaterials under mild conditions poses a great challenge, especially for metal-catalysed multiphase preparation. This work proposes an efficient method that utilizing high-density ultrasound to enhance the liquid-liquid interfacial reaction system. Iron-doped carbon dots (Fe-CDs) are successfully synthesized in such a normal temperature and atmospheric-pressure reaction condition. It is shown that transient cavitation provides a high-temperature and high-pressure microenvironment for the preparation of Fe-CDs. Moreover, the size of the reactant droplets is reduced from 200.0 ± 17.3 μm to 8.1 ± 2.9 μm owing to the acoustic flow and cavitation effects, which increases the specific surface area of the two reacting phases and improves the mass transfer coefficient by more than 252.0 %. As a result, the yield increases by more than an order of magnitude (from 0.7 ± 0.1 % to 11.9 ± 0.2 %) and the Fe doping rate reaches 20.9 %. The photocatalytic oxidation conversion of 1,4-Dihydropyridine (1,4-DHP) using the obtained Fe-CDs is as high as 98.2 %. This research gives a new approach for the efficient and safe production of Fe-CDs, which is promising for industrial applications.
研究领域:
材料科学
·
化学工程
·
环境科学
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121659
·
IF 7.5
Xinrui Lv,Huinan Sun,Zhijia Wu,Wei Gao,Mingshu Bi,Yufeng Wu
The study employed a synergistic surface-band engineering strategy to prepare a novel g-C 3 N 4 -based photocatalyst for the efficient and safe degradation of nitrobenzene (NB), a typical recalcitrant pollutant. Fe 0.010 /LCDs-TCN exhibited a higher density of active sites, a broader visible light absorption range, and a more effective separation and transfer of charge carriers. Importantly, Fe 0.010 /LCDs-TCN displayed a bandgap of 2.59 eV, with a valence band of + 2.04 eV and a conduction band of −0.55 eV. This narrowed bandgap, along with an optimized band potential, enabled the simultaneous generation of crucial active species ·OH and ·O₂⁻ from water and O₂. This mechanism skillfully balanced visible light absorption and redox capability. Regarding degradation performance, degradation rates reached up to 93 % for NB within 4 h, and 98 % for nitrophenols within only 60 min. Moreover, this system exhibited strong stability against pH variations and coexisting ions. The 5 cyclic experiments achieved high degradation efficiency of 74.3–94.7 %. The QSAR-based ECOSAR and Toxicity Estimation Software Tool (T.E.S.T.) confirmed a significant reduction in acute and chronic toxicity and mutagenicity of NB degradation system. This work offers a novel perspective on regulating g-C 3 N 4 by balancing light absorption and redox capability, providing a promising strategy for safe, efficient, and sustainable water purification technologies.
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高影响因子
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