查找使用阿拉丁产品的科研文献

A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme

Sun Ying,Lin Tianran,Zeng Cuihong,Jiang Gaoyan,Zhang Xuanhan,Ye Fanggui,Zhao Shulin

A self-correcting fluorescent assay of tyrosinase (TYR) was developed by utilization of Fe-MIL-88B-NH 2 as a peroxidase-like nanozyme and a capture probe. Fe-MIL-88B-NH 2 nanozyme was selected as an electron donor, and the oxidization product (dopamine- o -quinone) acts as an energy acceptor. First, TYR catalyzes the oxidation of tyramine hydrochloride to dopamine and then to dopamine- o -quinone. Second, Fe-MIL-88B-NH 2 with intrinsic peroxidase-like activity decomposes H 2 O 2 to produce ·OH radicals, which further accelerate the oxidation of dopamine to dopamine- o -quinone. Excessive H 2 O 2 and ·OH radicals reduce the interferences from ascorbic acid at the same time providing a self-correcting ability. Dopamine- o -quinone reacts with -NH 2 groups on the ligand of Fe-MIL-88B-NH 2 through Michael reaction which results in fluorescence quenching. Under 365-nm excitation, the fluorescence emission intensity at 452 nm gradually decreased with increasing TYR concentration varying from 0 to 10 U mL −1 . The linear range is from 1 to 5 U mL −1 and the detection limit is 0.05679 U mL −1 . This self-correcting fluorescent assay of tyrosinase exhibits good sensitivity and selectivity which is also successfully applied for tyrosinase inhibitor detection. Graphical abstract Schematic representation of fluorescent assay for tyrosinase determination based on Fe-MIL-88B-NH 2 nanozyme. A self-correcting fluorescent assay for tyrosinase was developed based on the Fe-MIL-88B-NH 2 nanozyme.

Fe/Cl/N triply-doped bamboo-like structure wrapped with Fe3C nanoparticles for electrochemical selective nitrite detection

Lufang He,Zhuo Liu,Yuchi Zhang,Le Han,Yan Xu

Nitrite is commonly found in the natural environment and in everyday human activities. However, excessive nitrite consumption can potentially harm human health. Consequently, it is crucial to develop a reliable and sensitive method for nitrite detection. In this work, trichloroacetic acid functionalized Cl-Fe-MIL-88B metal-organic framework is obtained through nucleophilic reaction between animated Fe-MIL-88B and trichloroacetic acid, which is then annealed with melamine in an N 2 atmosphere to produce the Fe/Cl/N triply-doped bamboo-like carbon nanotubes (CNTs) wrapped with Fe 3 C nanoparticles. Owing to the effective doping of Fe/Cl/N elements, the charge distribution and chemical activity of the bamboo-like structure are tailored, greatly improving the conductivity and facilitating electron transfer of the composite for potential electrocatalytic reaction. The Fe 3 C nanoparticles wrapped inside the CNTs contribute to expose more active sites and provide effective surface area. Accordingly, the Fe/Cl/N doped bamboo-like structure modified glassy carbon electrode shows excellent electrochemical nitrite sensing properties with a high sensitivity of 1060 µA cm −2 mM −1 , a low detection limit of 0.61 µM in a wide linear concentration range of 5–5000 μM, as well as good anti-interference and long-term stability. Also, the electrochemical sensor has a satisfactory recovery rate for detecting nitrite ions in spiked milk samples. This work proposes a simple precursor chlorination and pyrolysis strategy to obtain metal-filled bamboo-like structure with high electrical conductivity and electrocatalytic properties, endowing great potential in food safety and environment monitoring.

A chemiluminescence metalloimmunoassay for sensitive detection of alpha-fetoprotein in human serum using Fe-MIL-88B-NH2 as a label

Jingrong Zhou,Zhou Long,Yunfei Tian,Xiaodong Ding,Lan Wu,Xiandeng Hou

Synthesis of Uniformly Covered Fe-MOF@COF Heterostructures for Boosting Photo-Fenton Catalysis

Zhang Xue-Feng,Chang Tian-Long,Guo Na,Jia Guo-Liang,Li Xiao-Bing,Zhao Zhao-Ye,Wang Hui,Wang Jun-Chuan,Wu Xiang-Feng,Pan Cheng-Si,Liu Lei,Yang Lin-Lin

Fe-based MOFs (Fe-MOFs) are excellent photocatalysts and have synergy well with Fenton reagents relative to other MOFs. In this work, a series of uniformly covered NH 2 -Fe-MIL-88B@TpPa-1-COF composites were synthesized using an in-situ anchoring growth strategy, which used F127 as functional molecule to decorate NH 2 -Fe-MIL-88B nanoparticles to eliminate their surface electrostatic repulsion with Tp molecules during the subsequent coating procedure. Meanwhile, the -NH 2 groups in the skeleton of NH 2 -Fe-MIL-88B could also be used as anchors to covalently connect TpPa-1-COF shell and migration channels for effective charge transfer. This uniformly covered core–shell structure would endow these composites with much more contact area and imine bond linkage between the Fe-MOFs core and COFs shell. Compared with the random packing structure, the uniformly covered Fe-MOF@COF-3 composite possessed a higher proportion of Fe 2+ to Fe 3+ . As a result, the optimized Fe-MOF@COF-3 catalyst could achieve the highest photo-Fenton degradation efficiency of 93.9% for tetracycline hydrochloride (TC⋅HCl), which was much higher than 54.8% of pure NH 2 -Fe-MIL-88B. In addition, the uniform TpPa-1-COF shell could further effectively enhance the stability of NH 2 -Fe-MIL-88B by protecting Fe ions from leaching, and the toxicity of the water samples treated with our photo-Fenton degradation process declined obviously. All these merits will endow Fe-MOF@COF-3 photo-Fenton catalyst great potential application value as in the field of environmental governance.

One-step pyrolytic synthesis of small iron carbide nanoparticles/3D porous nitrogen-rich graphene for efficient electrocatalysis

Hao Huang,Xun Feng,Cuicui Du,Siyuan Wu,Wenbo Song

Uniform iron carbide nanoparticles (Fe3C, ∼10 nm), size evolved from nano-scaled Fe-MIL-88b, were one-pot pyrolytically embedded in 3D porous N-rich graphene. Extra ORR catalytic activity with four-electron selectivity was achieved in an alkaline electrolyte. The onset and peak potential were 10 mV and 40 mV more positive, respectively, than commercial Pt/C.