CATALYSIS COMMUNICATIONS
·
2022
·
IF 3.51
Sizhan Wu,Hangdao Qin,Hao Cheng,Wei Shi,Jing Chen,Jiming Huang,Hui Li
A novel sulfonic-functionalized MnFe 2 O 4 (MnFe 2 O 4 -HSO 3 ) Fenton nanocatalyst was prepared and tested for the degradation of three antibiotics from different categories. The effect of category of the antibiotic was investigated and the obtained results indicated that the degradation rate was the highest for erythromycin, lower for tetracycline and the lowest for amikacin. Moreover, the role of -HSO 3 was investigated by a series of comparative experiments between MnFe 2 O 4 and MnFe 2 O 4 -HSO 3 . The introduction of -HSO 3 prevented the leaching of metals and promoted the decomposition of H 2 O 2 into •OH radicals. Finally, the excellent stability of MnFe 2 O 4 -HSO 3 was verified.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 59
·34652-34657
·
IF 3.049
Shengling Li,Duanlin Cao,Zhiyong Hu,Zhichun Li,Xianjiao Meng,Xinghua Han,Wenbing Ma
In this study, a highly selective chemosensor ML based on a BODIPY fluorescent chromophore was synthesized for sequential recognition of Cu2+ and HSO3− in a CH3OH/H2O (99 : 1 v/v) system, which contained three recognition sites and its structure characterized by 1H NMR, 13C NMR and ESI-HR-MS. The sensor ML showed an obvious “on–off” fluorescence quenching response toward Cu2+ and the ML-Cu2+ complex showed an “off–on” fluorescence enhancement response toward HSO3−. The detection limit of the sensor ML was 0.36 μM to Cu2+ and 1.4 μM to HSO3−. In addition, the sensor ML showed a 1 : 3 binding stoichiometry to Cu2+ and the recovery rate of ML-Cu2+ complex identifying HSO3− could be over 70%. Sensor ML showed remarkable detection ability in a pH range of 4–8.
研究领域:
分析化学
·
生物化学
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 40
·19011-19018
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IF 3.591
Qiuying Song,Bo Zhou,Dongyu Zhang,Haijun Chi,Hongmin Jia,Peixun Zhu,Zhiqiang Zhang,Qingtao Meng,Run Zhang
The development of well-designed fluorescence probes for the monitoring of redox homeostasis in biosystems has attracted significant research interest owing to their non-invasive and real-time detection capability in vivo. In this work, a reversible near-infrared (NIR) fluorescence probe (XC) was designed and synthesized for the monitoring of HSO3−/H2O2-regulated cycles in vivo. The XC probe contains a D–π–A–π–D conjugated structure with a reactive CC double bond in the benzopyrylium moiety. In the presence of HSO3−, a nucleophilic addition reaction with the unsaturated carbon atom of XC occurred and rearranged the structure from the positively charged benzopyrylium moiety to neutral chromene. The HSO3−-induced nucleophilic addition product (XC-SO3) can be oxidized to the native XC, resulting in the reversible responses to HSO3−/H2O2 cycles. In the presence of HSO3−, XC presented a significant decrease in the absorption and emission spectra, as well as a solution colour change from blue to colourless under physiological conditions (pH = 7.4), which allows for the detection of HSO3− by the “naked eye”. By further incubation of XC-SO3 with H2O2, the spectroscopic and colour signals were recovered. Biologically relevant species including anions, reactive oxygen species (ROS), biothiols and cations induced negligible spectroscopic responses. The detection limits of XC for HSO3− and XC-SO3 for H2O2 were calculated to be 1.02 μM and 0.84 μM, respectively. XC has several advantages such as high selectivity, reliability at physiological pH and low cytotoxicity, which enable its application in biological samples. Fluorescence imaging experiments in live adult zebrafish and live nude mice demonstrated that XC has the potential to monitor the HSO3−/H2O2-regulated redox homeostasis in biosystems. The practical applications of XC were also demonstrated by the quantitative analysis of HSO3− in white wine and sugar samples.
研究领域:
生物化学
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分子生物学
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分析化学
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产品关联
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2021
·
IF 4.098
Weiliang Shen,Hanhan Xu,Jing Feng,Wei Sun,Guoxing Hu,Yonghong Hu,Wenge Yang
Based on the principle of FRET, we have developed a ratiometric and colorimetric fluorescent probe TFBN, which can specifically recognize SO 2 derivatives (SO 3 2− /HSO 3 − ), and exhibit a transition from red to green fluorescence under 405 nm excitation. The probe TFBN owns the advantages of short response time (<3 min), quantitative detection SO 2 derivatives in two linear ranges, extremely low detection limit (39 nM), large Stokes shift (239 nm) and wide emission window gap (140 nm). In addition, the NBC structure was used as a fluorescent donor for FRET probes for the first time, which expanded the diversity of donors. Importantly, with low toxicity and good biocompatibility, the probe TFBN successfully detects exogenous and endogenous sulfites in living cells. These characteristics endow the probe TFBN can be successfully used in living cells and mouse imaging.
研究领域:
生物化学
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分析化学
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医学影像学
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DOI
PubMed
高影响因子
DALTON TRANSACTIONS
·
2023
·Vol. 52
·期 18
·6129-6137
·
IF 4
Peipei Wang,Jin Tong,Cong Meng,Qing Yuan,Wei Deng,Shu-Yan Yu,Hong-Wei Ma
Owing to their structural designability and tuneable properties, supramolecular metal–organic complexes have recently emerged as promising candidates for the sensing and detection of molecules and anions. Herein, we synthesised three tripyrazolate-linked [M6L2] metallocages with the formulas [(bpyPd)6L2](NO3)6 (1), [(dmbpyPd)6L2](NO3)6 (2), and [(phenPd)6L2](NO3)6 (3) (H3L = tris(4-(5-(trifluoromethyl)-1H-pyrazol-3-yl)phenyl)amine, bpy = 2,2′-bipyridine, dmbpy = 4,4′-dimethylbipyridine, phen = 1,10-phenanthroline). Crystallography revealed that metal-directed coordination and the bidentate chelate behaviour of the ligand induced the self-assembly of supramolecular metal–organic cages. Notably, these cages were employed as turn-on fluorescence sensors for SO2 and its derivative (HSO3−) through a disassembly mechanism. Cages 1, 2, and 3 showed a highly selective and sensitive detection of HSO3− over other common anions in aqueous solutions and of SO2 gas over other common gasses, with an excellent anti-interference ability. These metallocages were subsequently applied as sensors in environmental and biological samples. This study not only enriches the ongoing research on metal–organic supramolecular materials but also facilitates the future preparation of stimuli-responsive supramolecular coordination complexes.
研究领域:
超分子化学
·
分析化学
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DOI
PubMed
高影响因子
TALANTA
·
2017
·
IF 4.162
Ting Yu,Guoxing Yin,Tingting Niu,Peng Yin,Haitao Li,Youyu Zhang,Haimin Chen,Ying Zeng,Shouzhuo Yao
A novel fluorescent probe ( E )-3-ethyl-2-(4-hydroxystyryl)-1,1-di-methyl-1 H -benzo-[ e ]indolium iodide (probe EDB) based on benzo[ e ]indolium was synthesized, which provided the simultaneous detection of SO 3 2- /HSO 3 - and HSO 4 - ion with different emission channels. Based on the principle of ion-induced rotation-displaced H-aggregates, when treated with NaHSO 4 , a fluorescence enhancement at 580 nm was observed with the excitation wavelength at 420 nm. While, in the advantage of the nucleophilic addition of SO 3 2- to the vinyl group, strong fluorescence was obtained at 455 nm when treated with Na 2 SO 3 with the excitation wavelength at 320 nm, along with obvious color change by naked eyes. So the probe could be applied to sense SO 3 2- /HSO 3 - and HSO 4 - ion via different excited and emission channels simultaneously. The probe was also applicable for fluorescence imagings of bisulfite and hydrosulfate in HeLa cells.
研究领域:
分析化学
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生物化学
·
医学
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DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Jian Wang,Haoyang Li,Weibo Xu,Bo Zhang,Yu Wang,Nan Chen,Qinghai Zhou,Tianrui Ren
A reversible colorimetric and ratiometric fluorescent probe ( QG-Py ) was developed for HSO 3 − detection. The probe showed large changes in absorbance and emission wavelength shift both with 155 nm when reacted with NaHSO 3 . Furthermore, probe QG-Py exhibited high selectivity and sensitivity to NaHSO 3 with quantitative analysis in real water samples through colorimetric and ratiometric methods. Interestingly, the reaction product ( QG-Py-SO 3 H ) displayed structural recovery to QG-Py induced by H 2 O 2 , accompanied with reversible optical properties . Probe QG-Py was established to visualize HSO 3 − /H 2 O 2 in MCF-7 cells. Importantly, QG-Py was also successfully applied for HSO 3 − /H 2 O 2 detection and imaging in rice roots and leaves, providing better understanding of the influence of SO 2 derivatives to crops, as well as a new and simple method for evaluating environmental pollution of SO 2 .
研究领域:
生物化学
·
环境科学
·
细胞生物学
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产品关联
DOI
高影响因子
ENVIRONMENTAL RESEARCH
·
2024
·
IF 7.7
Zhenbin Chen,Haohan Cai,Feng Huang,Zongping Wang,Yiqun Chen,Zizheng Liu,Pengchao Xie
β-lactam antibiotics, extensively used worldwide, pose significant risks to human health and ecological safety due to their accumulation in the environment. Recent studies have demonstrated the efficacy of transition metal-activated sulfite systems, like Fe(Ⅲ)/HSO 3 − , in removing PPCPs from water. However, research on their capability to degrade β-lactam antibiotics remains sparse. This paper evaluates the degradation of 14 types of β-lactam antibiotics in Fe(Ⅲ)/HSO 3 − system and establishes a QSAR model correlating molecular descriptors with degradation rates using the MLR method. Using cefazolin as a case study , this research predicts degradation pathways through NPA charge and Fukui function analysis, corroborated by UPLC-MS product analysis. The investigation further explores the influence of variables such as HSO 3 − dosage, substrate concentration , Fe(Ⅲ) dosage, initial pH and the presence of common seen water matrices including humic acid and bicarbonate on the degradation efficiency. Optimal conditions for cefazolin degradation in Fe(Ⅲ)/HSO 3 − system were determined to be 93.3 μM HSO 3 − , 8.12 μM Fe(Ⅲ) and an initial pH of 3.61, under which the interaction of Fe(Ⅲ) dosage with initial pH was found to significantly affect the degradation efficiency. This study not only provides a novel degradation approach for β-lactam antibiotics but also expands the theoretical application horizon of the Fe(Ⅲ)/HSO 3 − system.
研究领域:
环境科学
·
药学
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产品关联
DOI
PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Mengwen Yi,Xiangjun Liu,Jing Liu,Shengnan Li,Dandan Li,Xiangru Zhang,Nan Zhang,Yongbiao Wei,Dihua Shangguan
Sulfur dioxide, an essential gas signaling molecule mainly produced in mitochondria, plays important roles in many physiological and pathological processes. Herein, a near-infrared fluorescent probe, A1, with good mitochondria targeting ability was developed for colorimetric and fluorescence detection of HSO 3 - . Probe A1 has a conjugated cyanine structure that can selectively react with HSO 3 - through the nucleophilic addition. The reaction with HSO 3 - destroys the conjugated structure of probe A1, resulting in fluorescence quenching, and accompanied by color change of probe A1 solution from purple-red to colorless. Probe A1 showed high selectivity and good sensitivity to HSO 3 - in PBS. And the limit of detection was calculated to be 1.28 and 0.037 μM for colorimetry and fluorescence spectrophotometry respectively. In addition, probe A1 mainly entered the mitochondria in living cells, and was successfully used for imaging the exogenous/endogenous HSO 3 - in cells. These results suggest the potential applications of probe A1 in biological systems.
研究领域:
分析化学
·
生物化学
·
细胞生物学
·
荧光成像
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CHEMISTRY
·
2023
·
IF 8.8
Xiaoying Ma,Xiufeng Zhang,Buyue Zhang,Dawei Yang,Hongxia Sun,Yalin Tang,Lei Shi
Microenvironmental indicators in organisms drive the operation of different physiological functions. In contrast, disruption of microenvironmental homeostasis is often closely associated with various pathological processes. A novel dual-response fluorescent probe based on hemicyanine dye ( HT-Bzh ) was designed and synthesized for the detection of HSO 3 − and viscosity changes. The probe not only provides high sensitivity (limit of detection = 0.2526 μM) for the detection of HSO 3 − using the Michael addition reaction, but also allows the observation of fluorescence emission at 528 nm and thus the monitoring of viscosity changes through hindering of the twisted intramolecular charge transfer (TICT) mechanism. Additionally, dual-response probe has been successfully used to image living cells and detect real food samples. As a new designed tool, HT-Bzh shows excellent anti-interference capability and biocompatibility, which makes it have application potential in other biological systems and in-vivo imaging.
研究领域:
分析化学
·
生物化学
·
生物医学工程
·
细胞生物学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2017
·
IF 4.162
Zhuo Ye,Chong Duan,Ruilong Sheng,Junchao Xu,Hongying Wang,Lintao Zeng
Monitoring sulfur dioxide (SO 2 ) derivatives in environment is of great significance due to their harmful effects to the environment and human health. In this study, a fluorescent probe ( CZBT ) for SO 2 derivatives was prepared from 9-ethyl-9 H -carbazole-3,6-dicarboxaldehyde and 2-methyl-benzothiazolium, which displayed a noticeable color change from yellow to colorless along with a remarkable fluorescence change from yellow to blue in response to HSO 3 − . The probe could quantitatively determine the concentration of HSO 3 − with excellent selectivity, high sensitivity and low limit of detection. 1 H NMR and HR-MS spectra demonstrated that a selective 1, 4-nucleophilic addition occurred on the bridge double bond in CZBT . The probe was successfully used to determine the SO 2 derivatives in several real water samples with good recovery. Furthermore, the probe was employed for monitoring the level of intracellular HSO 3 − in HeLa (human cervical cancer) cells by fluorescence imaging. These results indicated that CZBT has a good capability for monitoring SO 2 derivatives in environment and living cells.
研究领域:
分析化学
·
环境科学
·
生物医学
✓ 已验证
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2019
·
IF 4.018
Wei Wang,Xian-Jing Han,Jin-Ting Liu,Jun-Ying Miao,Bao-Xiang Zhao
A new ratiometric fluorescence probe (named CPC) with high selectivity and sensitivity toward bisulfite (HSO 3 − ) based on a FRET platform was developed. Probe CPC was constituted by a coumarin-carbazole dyad with a large (pseudo) Stokes shift (197 nm). The limit of detection was measured to be as low as 18 nM and the signal-to-background ratio of fluorescence intensity was up to 73-folds, implying a high sensitivity of probe CPC toward HSO 3 − . What's more, probe CPC was successfully applied to the detection of endogenous HSO 3 − and specific imaging of lipid droplets in HepG2 cells.
研究领域:
生物化学
·
细胞生物学
✓ 已验证
DOI
高影响因子
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