Small
·
2021
·Vol. 17
·期 36
·2102879
·
IF 13.281
Nanzhu Nie,Dan Zhang,Zuochao Wang,Yingnan Qin,Xuejun Zhai,Bo Yang,Jianping Lai,Lei Wang
At present, it is still a great challenge to synthesize refractory Pt-based electrocatalysts with excellent active specific surface area, specific activity, and stability by a simple method. Here, a superfast and solvent-free microwave strategy is reported to synthesize refractory ultrafine (≈3 nm) Pt–lanthanide@Ketjen Black (PtM@KB, M = La, Gd, Tb, Er, Tm, and Yb) alloy with densely packed as efficient hydrogen evolution electrocatalysts in a domestic microwave oven for the first time. The optimized Pt 61 La 39 @KB delivers excellent hydrogen evolution reaction (HER) activity with a low overpotential of 38 mV (10 mA cm −2 ) and a high TOF value of 44.13 s −1 (100 mV) in 0.5 m H 2 SO 4 , and performs well in 1.0 m KOH. This method can also be used to grow catalysts on carbon cloth (CC) directly. PtLa@CC shows an overpotential of 99 mV (1000 mA cm −2 ) in 0.5 m H 2 SO 4 and can maintain activity after 500 h. Theoretical calculations reveal the enhanced stability and activity owing to the higher vacancy formation energy of Pt atoms and the optimized value of Δ G H* . Solvent-free microwave strategy constitutes a significant insight into the development of refractory electrocatalyst with ultrafine size and highly dense, which can also work well at high current densities.
研究领域:
材料科学
·
电化学
·
能源催化
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2016
·
IF 4.758
Li Wang,Coucong Gong,Yuan Shen,Wenhui Ye,Mengli Xu,Yonghai Song
In this work, a novel ascorbic acid (AA) ratiometric biosensor was prepared by using the PCN-333 (Al) metal-organic frameworks (MOFs) (PCN stands for porous coordination network) to encapsulate Ketjen black (KB) as catalyst for catalyzing oxidation of AA and thionine (Thi) as an internal reference signal simultaneously. The encapsulation of KB and Thi in the pores of PCN-333 (Al) MOFs not only improved efficiency of KB and Thi greatly because PCN-333 (Al) MOFs could effectively avoid the cohesion or aggregation of KB and Thi on electrode surface but also enhanced the stability of biosensors because they were immobilized in the pore firmly. Furthermore, PCN-333 (Al) MOFs could also selectively accumulate target analytes into their pores to enhance the selectivity of biosensors. The oxidation peak current of AA catalyzed by KB at −0.05 V increased with the increasing concentration of AA, while the oxidation peak current of Thi at −0.24 V kept constant, which resulted in a novel ratiometric biosensor for AA detection. The ratiometric biosensor exhibited a wider linear range from 14.1 ± 0.2 to (5.5 ± 0.1) х10 3 μM (R 2 = 0.998) and a lower detection limit of 4.6 ± 0.1 μM with high accuracy, selectivity, reproducibility and sensitivity. The ratiometric electrochemical approach is not only a new method for AA detection but also opens a new way for sensitive detection of other analytes.
研究领域:
分析化学
·
生物传感技术
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL BIOCHEMISTRY
·
2023
·
IF 2.9
Xuhuai Fu,Yunyao Lu,Yang Peng
Ultrasensitive detection of circulating tumor cells (CTCs) holds significant clinical importance in monitoring metastasis and therapeutic outcomes. In this study, we have developed a novel electrochemical sensing model based on nanomaterials for highly sensitive and specific determination of CTCs. A gold electrode co-modified with Ketjin black (KB) and Au nanoparticles (AuNPs) exhibits exceptional conductivity. By conjugating palladium-iridium cubic nanozyme (Pd–Ir CNE) with antibodies, we have created a detection probe capable of catalyzing hydrogen peroxide (H 2 O 2 ), thereby amplifying the output signal and resulting in significantly enhanced current on the electrode for detecting CTCs. The constructed immunosensor has achieved a detection limit of 2 cell mL −1 for model MCF-7 cells. Furthermore, the as-constructed electrochemical immunosensor can accurately detect whole blood-spiked target CTCs, showing great promise for clinical applications in early cancer diagnosis and prognosis.
研究领域:
医学诊断
·
生物材料学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Advanced Sustainable Systems
·
2023
·Vol. 9
·期 7
·2300233
·
IF 7.1
Sijie Yu,Yuwei Chen,Yangyang Huang,Huabin Sun,Yu Xie,Sihao Du,Wei Luo
NASICON (NAtrium Super Ionic CONductor)-structured Na 4 MnCr(PO 4 ) 3 has attracted attention as a promising cathode for sodium-ion batteries due to its high operating voltage and specific capacity contributed by multielectron reactions. Unfortunately, its intrinsic low electronic conductivity significantly hinders the release of specific capacity and rate capability, preventing its practical application. Herein, a carbon layer with dual conductive networks connected by chain-like Ketjen black (KB) is built on the surface of Na 4 MnCr(PO 4 ) 3 material. This novel Na 4 MnCr(PO 4 ) 3 /C@KB composite material exhibits improved rate capability of 61.2 mAh g −1 at 2 C compared to 19.5 mAh g −1 of Na 4 MnCr(PO 4 ) 3 /C and high reversible capacity of 88.0 mAh g −1 at 1 C with 73% capacity retention after 100 cycles. The enhanced electrochemical performance can be ascribed to an increase of electronic conductivity enabled by the dual conductive 3D network construction and an adequate infiltration of electrolyte by substantial pores existence in carbon layer. A promising dual conductive network design strategy is demonstrated here for improving the performance of NASICON-structured cathodes.
研究领域:
材料科学
·
电化学
·
能源存储
·
无机化学
·
纳米材料
·
固态离子学
✓ 已验证
DOI
高影响因子
FUEL
·
2025
·
IF 7.5
Xinhao Zhang,Jinjuan Zhao,Sizhuo Ma,Ruifa Jin,Shuwen Li
The integration of diverse carbon materials using a suitable “linker” to form a supporting matrix is recognized as an effective strategy for fabricating efficient and durable electrocatalysts for the methanol oxidation reaction (MOR). Herein, we design and fabricate an advanced electrocatalyst consisting of the coupling Ketjen black (KB) with carbon nanotubes (CNTs) by polydopamine-linking anchoring “surface-clean” Pd nanocrystallines (Pd/KB-PDA-CNTs). As an alkaline-MOR electrocatalyst, the fabricated-Pd/KB-PDA-CNTs demonstrates dramatically enhanced electrocatalytic performance, notably superior activity and durability compared to commercial Pd/C. The electrochemical experimental assessments combined with systematic characterizations show that the polydopamine-linking is pivotal significantly to enhance alkaline-MOR electrocatalytic behavior. Briefly, coupling KB with CNTs via polydopamine-linking not only offers plentiful mass/electron/proton-transfer channels, but also introduces affluent functional groups (hydroxyl groups, imine/amine, catechol and benzene rings), which endows abundant reactive sites for nucleating, growing and anchoring Pd nanocrystallines thereby enabling an efficient regulation of the size, morphology, distribution and electronic state for Pd. The implementation of the coupling KB with CNTs by polydopamine-linking indicates that the coupling different types of carbon materials by polydopamine-linking is a promising strategy for rational designing advanced functional materials for application in electrocatalysis and beyond.
研究领域:
电催化
·
材料化学
·
纳米材料
·
能源化学
·
表面科学
·
物理化学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2015
·
IF 4.504
Chaolumen Wu,Haibin Wang,Chenbo Liao,Jun Yang,Lei Li
A hybrid air-electrode composed of a mixture of fluorinated carbon (CF x ) and Ketjen black (KB) active carbon composite materials was prepared to improve performance of Li-O 2 battery . In the hybrid air-electrodes, four kinds of CF x materials including fluorinated graphite, fluorinated carbon fiber, fluorinated coke and fluorinated black carbon were utilized as lithium insertion materials. The physical properties and morphologies of the KB and CF x carbon materials were characterized by Brunauer-Emmett-Teller (BET), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and Scanning electron microscopy (SEM) measurements. Compared with the conventional KB air-electrode, all the CF x /KB hybrid air-electrodes in Li-O 2 batteries showed higher specific discharge capacity, especially at high current density . Among these CF x /KB hybrid air-electrodes, the fluorinated graphite based electrode showed the best electrochemical performance in Li-O 2 battery due to its highest discharge capacity of the fluorinated graphite material in the Li/CF x primary battery, highest specific surface area, and highest total pore volume . The electrochemical performance of Li-O 2 and Li-air batteries using the hybrid air-electrodes with the different fluorinated graphite: KB weight ratio, including specific charge and discharge capacity, cycling stability and rate capability were systematically investigated. At a current density of 0.5 mA cm −2 , the fluorinated graphite based air-electrode delivered a high specific discharge capacity of 1138 mAh g −1 in Li-O 2 batteries, which was more than four times than that of the conventional KB air-electrode (265 mAh g −1 ) under same testing conditions. The battery assembled with the fluorinated graphite based air-electrode exhibited better cycling stability than that of the battery assembled with the conventional KB air-electrode.
研究领域:
电化学
·
能源材料
·
纳米材料
·
电池技术
·
材料科学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Yujie Chen,Zhaode Mu,Jianli Zuo,Min Qing,Jing Zhou,Lijuan Bai
A novel aptasensor for the detection of kanamycin (KNM) was developed based on dual signal amplification through nanomaterials and DNA rolling machines. Firstly, a composite consisting of the covalent organic framework (COF), ketjen black (KB) and toluidine blue (Tb), was synthesized for signal generation. Tb molecules were loaded into the composite and combined with AuNPs to serve as tracer label. Secondly, the wDNA-loaded Fe 3 O 4 magnetic beads (wDNA@MBs) as the DNA walking legs, with cleavage by Mg 2+ -driven DNAzyme, the DNA walking legs can move along the sDNA-decorated MBs surface, converting the target KNM into numerous output DNA strand, achieving sensitive amplification. With a low detection limit of 0.66 fM and a wide linear dynamic range from 10 fM to 100 nM, this aptasensor showed good results in the detection of KNM in real samples. Therefore, we envision it can provide a useful method for KNM detection in actual samples.
研究领域:
生物化学
·
食品科学
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Meimei Guo,Fang Li,Qiwen Ran,Gan Zhu,Yunhang Liu,Jiale Han,Guifang Wang,Hongyuan Zhao
A novel methyl parathion (MP) electrochemical sensor was fabricated from the multifunctional composite of Zr-based metal–organic framework (UiO-66) and Ketjen black-carbon nanotubes (KB-CNTs), which achieved the sensitive detection of MP in food samples. For the UiO-66/KB-CNTs composite, Zr-based UiO-66 with Zr-OH groups possessed good affinity for phosphate groups on methyl parathion molecules, which enhanced the selective recognition and enrichment capability towards MP, and KB-CNTs possessed three-dimensional interconnected carbon conductive network with synergistic point-line carbon conductive contact, which showed excellent electrical conductivity. Moreover, KB with pearl chain-like structure and more conductive contact points realized the full contact between KB-CNTs and UiO-66 with Zr-OH groups. The fabricated UiO-66/KB-CNTs/GCE sensor showed good MP detection performance with low limit of detection of 1.53 nM in linear MP concentration range of 0.005–12 µM. Moreover, the fabricated sensor showed good repeatability, reproducibility, and selectivity. A good practical feasibility can be achieved at the UiO-66/KB-CNTs/GCE sensor for the detection of MP in grape juice and apple juice samples (Recovery rate: 96.14–102.93, relative standard deviation: 2.17%-4.95%).
研究领域:
分析化学
·
环境科学
·
食品科学
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2022
·Vol. 12
·期 11
·6409-6415
·
IF 4.036
Hong-qi Xia,Tingting Gu,Ruiyi Fan,Jiwu Zeng
Electrocatalysis of bioflavonoids in carbon nanomaterials plays an important role in electrochemical sensors for the detection of their content in fruits. In this study, three types of carbon nanomaterials with 1D, 2D, and 3D structures, namely carbon nanotubes (CNTs), graphene oxide (GO), and Ketjen black (KB), were modified onto glassy carbon electrodes for the electrocatalysis of hesperidin and naringin, which are two important bioflavonoids in fruits. As a result, the CNT-modified electrodes showed the highest electrocatalytic activity for both hesperidin and naringin compared to GO and KB. The morphology and surface chemistry of the carbon nanomaterials were characterized. The structural defects and carbon status of carbon nanomaterials are proposed to be the most important factors affecting the electrocatalysis of hesperidin and naringin. Finally, a CNT-based electrochemical sensor was fabricated to simultaneously detect hesperidin and naringin. Real sample tests on the fruit extract of Citrus grandis “Tomentosa” show that the proposed electrochemical sensors with high recovery thus could be employed in practical applications.
研究领域:
电化学
·
纳米技术
·
分析化学
·
食品科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 4
·1-11
·
IF 6.232
Peng Yang,Peng Yuhang,Tang Sitian,Shen Huawei,Sheng Shangchun,Wang Yonghong,Wang Teng,Cai Juan,Xie Guoming,Feng Wenli
An integrated electrochemical immunoassay is described for the determination of circulating tumor cells (CTCs). For the first time, Ketjen black (KB), which is a superconductive carbon material, was incorporated with Au nanoparticles (AuNPs) and used to modify the surface of gold electrodes. A cocktail of anti-epithelial cell adhesion molecules (EpCAM) and anti-vimentin antibodies was chosen to capture the CTCs. Palladium-iridium-boron-phosphorus alloy-modified mesoporous nanospheres (PdIrBPMNS) served as a catalytic tag to amplify the current signal. Glycine-HCl (Gly-HCl) was used as an antibody eluent to release and collect the captured CTCs from the electrodes for further clinical research without compromising cell viability. The response of the method increased linearly from 10 to 1 × 10 6 cells mL −1 CTCs, while the detection limit was calculated to be as low as 2 cells mL −1 . This method was successfully used to determine CTCs in spiked blood samples and demonstrated good recovery.
Ketjen black/AuNPs was incorporated in the electrochemical platform to enhance the electron transfer ability of the electrode surface. PdIrBP mesoporous nanospheres were used to amplify DPV signal in this assay. The introduction of Gly-HCl realized nondestructive recovery of circulating tumor cells.
研究领域:
生物化学
·
纳米技术
·
电化学
·
癌症研究
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2023
·Vol. 58
·期 23
·9633-9645
·
IF 4.5
Hu Rongqin,Mu Zhaode,Gong Feng,Qing Min,Yuan Yonghua,Bai Lijuan
Human epididymis protein 4 (HE4) is a highly sensitive and specific biomarker for diagnosing ovarian cancer. In this work, a new electrochemical aptasensor for rapid and sensitive detection of HE4 was constructed. Firstly, metal–organic framework/ketjen black (NH 2 -MIL-53(Al)/KB) composite with abundant amino groups and large specific surface area was prepared as signal amplifier to anchor gold nanoparticles (AuNPs). Subsequently, signal probe (SP) and a large amount of electroactive toluidine blue (Tb) were attached on AuNPs to form the tracer label, producing a distinct electrochemical detection signal. Moreover, Ni 3 (HITP) 2 was modified by poly(diallyldimethylammonium chloride, PDDA) to obtain PDDA/Ni 3 (HITP) 2 , and then it was covered with deposited gold nanocrystals (DpAu) to form the sensing platform, which increased the electrical conductivity, specific surface area and the loading of triple-helix assembled probes (TAP). Target HE4 was bound to its aptamer in the outer layer of the TAP, leaving a separate capture probe (CP) on the electrode surface that can bind with the tracer label. The proposed aptasensor for HE4 detection showed a wide linear range from 1 to 10 nM with a detection limit of 0.41 fM. In addition, the aptasensor has good selectivity, stability and reproducibility. More importantly, this method showed satisfactory results in clinical serum sample analysis compared with ELISA, possessing application prospects in ovarian cancer diagnosis.
研究领域:
生物传感器
·
分析化学
·
纳米技术
·
癌症诊断
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2024
·
IF 10.7
Tingting Zhang,Congcong Zhang,Xue Li,Dongfang Ren,Mingshuang Zheng,Shuo Zhang,Fangping Yuan,Xin Du,Zhenguo Zhang
Prostaglandin E2 (PGE2), an eicosane, regulates the physiological activity of inflammatory cells and represents a potential therapeutic target for facilitating tissue repair in vivo. In our work, an electrochemical immunosensor employing Ketjen black-Au nanoparticles (KB–Au) and poly tannic acid nanospheres conjugated with anti-PGE2 polyclonal antibody (PTAN-Ab) was designed to ultra-sensitively analyze PGE2 levels secreted by living cells and tissues. Antibody assembly strategies were explored to achieve signal amplification. Moreover, we studied the therapy effects of docosahexaenoic acid (DHA), arachidonic acid (AA), hyaluronic acid (HA), and small molecule 15-hydroxyprostaglandin dehydrogenase inhibitor (SW033291) on inflammation and evaluated the protective functions of HA and SW033291 in a murine model subjected to colitis induced by dextran sulfate sodium (DSS) using the developed sensor. The sensor exhibited a linear range of 10 −5 –10 6 fg/mL and a detection limit (LOD) of 10 −5 fg/mL. Fetal bovine serum (FBS) samples were used to achieve high recovery of target analytes. This study not only presents an effective strategy for ultra-sensitively monitoring PGE2 but also provides valuable insights into assessing the degree of inflammation and the therapeutic effect of related drugs. Research on human health monitoring and regenerative medicine could greatly benefit from the findings.
研究领域:
分析化学
·
生物化学
·
免疫学
·
药理学
·
再生医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）