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P-Ti配位
ACS Applied Nano Materials · 2019 · IF 0

Synergistic Antibacterial Activity of Black Phosphorus Nanosheets Modified with Titanium Aminobenzenesulfanato Complexes

Zhibin Li,Lie Wu,Huaiyu Wang,Wenhua Zhou,Hanxia Liu,Haodong Cui,Penghui Li,Paul K. Chu,Xue-Feng Yu

A two-dimensional (2D) antimicrobial nanoagent is synthesized by incorporating the titanium aminobenzenesulfanato complexes (Ti-SA4) onto black phosphorus nanosheets (BPs). The strong P–Ti coordination between Ti-SA4 and BPs results in the high loading capacity (∼43%) of Ti-SA4 onto BPs and enhances the stability of BPs against oxidation. Compared to bare BPs and Ti-SA4, the Ti-SA4@BPs exhibit improved antibacterial efficacy, and most of the bacteria are inactivated within 3 h with a dose of only 50 μg/mL. The underlying antibacterial mechanism is investigated. This proposed Ti-SA4@BPs have great potential in clinical applications, and the results provide insights into the design and synthesis of 2D antibacterial nanoagents.

研究领域: 材料科学 · 纳米技术 · 生物医学工程 · 微生物学
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