Journal of Environmental Chemical Engineering
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2025
·
IF 7.2
Ruiqi Liu,Lihong Wang,Tao Lan,Jin Hua,Jingxuan Zhang
In this study, an innovative method for preparing biochar aimed at enhancing the QuEChERS pesticide residue analysis pretreatment technology was developed. The method is ecofriendly and cost-effective. A microporous biochar with a high specific surface area (351.43 m²·g −1 ) was successfully produced using corn stover as the raw material. The preparation process involved sodium hypochlorite delignification, hydrothermal pyrolysis, and slow pyrolysis. This biochar effectively removes pigments and lipids from chrysanthemum extracts, and its three-dimensional structure offers additional adsorption sites for planar compounds and sulfonylurea pesticides. The cost for preparing biochar is approximately 0.5 USD/g, which is significantly lower than that of traditional GCB, offering substantial advantages in both cost and environmental sustainability. The biochar developed in this study not only provides an efficient and economical material for pesticide residue analysis pretreatment but also contributes significantly to the advancement and application of ecofriendly pesticide residue detection technologies.
研究领域:
环境科学
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分析化学
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产品关联
DOI
高影响因子
Heliyon
·
2023
·
IF 4
Chengcheng Jin,Ting Wang,Tingting Zhao,Wen Jiang,Xiaolan Zhen,Hui Li
Objective To determine the concentrations of nine drugs used in the treatment of cardiovascular diseases in human plasma through QuEChERS pre-treatment combined with ultra-performance liquid chromatography-tandem mass spectrometry. Plasma samples were extracted with 3 mL of acetonitrile, 400 mg of anhydrous magnesium sulfate as a salting agent, and 20 mg of C18 as a sorbent. An Agilent Poroshell 120 EC-C18 column (4.6 × 100 mm, 2.7 μm) was selected and methanol-0.1 % water was used as the mobile phase, and ESI positive ion detection mode was selected. Results: The plasma concentrations of nisoldipine, metoprolol, and prazosin exhibited good linearity within the range of 0.05–4.0 ng/mL (r > 0.99), while atenolol, bisoprolol, propranolol, rosuvastatin, and atorvastatin showed linearity within the range of 0.5–40 ng/mL (r > 0.99). Fluvastatin showed good linearity within the range of 5.0–400 ng/mL. The accuracy of the method ranged from 94.15 to 110.62 %, while the recovery levels were in the range of 85.23 %–115.13 %. The matrix effects were observed between-6.54 % and 12.43 %. The intra-day and inter-day RSD was <15 % for the three concentrations of low, medium, and high. Conclusion The proposed method is rapid, accurate, specific, simple, reproducible, and suitable for the simultaneous measurement of the concentrations of nine drugs used in the treatment of cardiovascular diseases in human plasma.
研究领域:
分析化学
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药理学
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临床医学
✓ 已验证
DOI
高影响因子
Arabian Journal of Chemistry
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2019
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IF 3.298
Qianjun Liu,Jiepeng Tang,Di Chen,Yangmei Zhou,Qintie Lin,Xiaoguo Ma,Min Zhang,Huawen Hu
To detect, identify, and quantify the polycyclic aromatic hydrocarbons (PAHs) released into the environment, the PAHs need to be isolated from the soil matrix. In this work, a modified quick, easy, cheap, efficient, rugged and safe (QuEChERS) method with ionic liquid was combined with liquid chromatography to identify 16 selected PAHs in soil. Ionic liquid 1-hexyl-3-methylimidazolium hexafluorophosphate ([Hmim]PF 6 ) was applied as an extractant component to enhance the process. The [Hmim]PF 6 content in acetonitrile (ACN) was optimized. The [Hmim]PF 6 modified QuEChERS method has the advantages defined by its name and a similar recovery to other extraction methods reported in the literature. Adding [Hmim]PF 6 may eliminate the co-extract proportion and achieve a more effective extraction. Compared with ACN alone, the matrix effect (ME) of ACN containing 5% [Hmim]PF 6 was reduced by approximately 35%. Additionally, the ME of using ACN containing [Hmim]PF 6 without a clean-up procedure was similar to that of using ACN followed by a clean-up procedure. The recoveries of the QuEChERS method implemented with [Hmim]PF 6 ranged from 75.19% to 100.98%. The limits of detection (LOD) and limits of quantification (LOQ) ranged from 0.86 to 4.51 µg/kg and from 2.87 to 15.13 µg/kg, respectively.
研究领域:
环境科学
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分析化学
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产品关联
DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2013
·Vol. 29
·期 4
·653-656
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IF 0.735
Wang Wen-wen,Gao Fu-kai,Li Gui-zhi,Liu Zhen-bo,Liu Yong-ming
A simple, environmentally friendly and high efficient extraction method was proposed for the determination of five phthalates in aquatic products by gas chromatography combined with mass spectrometry detector (GC-MS). When this method was adopted, samples were pretreated by modified QuEChERS(quick, easy, cheap, effective, rugged and safe) method. An environmentally friendly extractant(ethanol aqueous solution) replaced toxic acetonitrile for extracting phthalates in the protein-matrix samples. Fluorescence quenching spectra of bovine serum albumin(BSA) with phthalates show that there was a high-affinity interaction between phthalate and protein, decreasing the extraction efficiency of phthalates from fish samples. However, in the 80%(volume fraction, φ ) ethanol aqueous solution, a slow but full protein denaturation takes place, which would cause the unfolding of protein and the release of phthalates. Meanwhile, the fat-soluble impurities are extracted less in φ (ethanol) 80% aqueous solution than in either φ (ethanol) 100% or hydrophobic solvents in the liquid-liquid extraction procedure. Therefore the purification steps were greatly simplified. Overall recoveries were 81.77%–90.5% with limits of detection between 2.53 and 9.61 μg/L, and relative standard deviation values at 1.15%–4.85%. The proposed approach was satisfactorily applied to the determination of phthalates in real aquatic products, such as fish, shrimp and oyster.
研究领域:
分析化学
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环境科学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2017
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IF 4.529
Nadeem Muhammad,Qamar Subhani,Fenglian Wang,Chaoyan Lou,Junwei Liu,Yan Zhu
A new simple, isocratic, selective and highly sensitive method has been developed for the simultaneous separation and determination of two plant growth regulators (PGRs): 2-(1-Naphthyl)acetic acid (NAA) and 2-(Naphthalen-1-yl)acetamide (NAD). Both PGRs were extracted by modified and miniaturized ion chromatography-Quick, Easy, Cheap, Effective, Rugged and Safe (IC-QuEChERS) method from ten food samples. The separation and sensitive determination were carried out by using ion chromatography coupled with fluorescence and ultraviolet (IC-FLD/UV) detector. The proposed analytical and extraction methods were validated by using blank samples, fortified with a standard solution of these two PGRs at three concentration levels 5, 15 and 25 µg/kg. The method showed good linearity (r 2 ≥ 0.980), satisfactory recoveries (76.3–112) with tolerable precision having relative standard deviations less than 15.4% (RSDs, n = 3). The limit of detection and limit of quantification were also in the range of 0.08–6.6 ng/kg and 2.2–20 ng/kg, respectively.
研究领域:
分析化学
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植物学
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产品关联
DOI
PubMed
高影响因子
MOLECULES
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2022
·Vol. 27
·期 21
·7636
·
IF 4.927
Xuyan Fan,Tao Tang,Song Du,Ningning Sang,Hao Huang,Chenghui Zhang,Xueping Zhao
A rapid, efficient, simple, and high-throughput method for the simultaneous determination of 108 pesticide residues in three traditional Chinese medicines (TCMs) was established, comprising an improved QuEChERS method in combination with HPLC-MS/MS based on mixed samples. A quantity of 10 mL of acetonitrile was used as extraction solvent, and 10 mg of amino-modified multi-walled carbon nanotubes (MWCNTs-NH2) and 150 mg of anhydrous magnesium sulfate (MgSO4) were selected as sorbents for dispersive solid phase extraction. The performance of the method was verified according to the analytical quality control standards of SANTE/11813/2017 guidelines. With good linearity (R2> 0.9984) in the range of 2–200 μg/L for all pesticides in the selected matrices, and good accuracy, precision, and high sensitivity, the recoveries were in the range of 70–120% for more than 95% of the pesticides, with a relative standard deviation (RSD) of less than 16.82% for all. The limit of detection (LOD) and limit of quantification (LOQ) of the method were 0.01–3.87 μg/kg and 0.07–12.90 μg/kg, respectively, forFritillaria thunbergiiMiq (F. thunbergii),Chrysanthemum MorifoliumRamat (C. morifolium), andDendrobium officinaleKimura et Migo (D. officinale). The method was successfully applied to 60 batches of actual samples from different regions.Keywords:pesticide residue;QuEChERS;MWCNTs-NH2;traditional Chinese medicines
研究领域:
分析化学
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药学
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产品关联
DOI
PubMed
高影响因子
Food Chemistry-X
·
2024
·
IF 6.5
Shaowei Li,Yuting Yuan,Liangxiao Zhang,Fei Ma,Peiwu Li
This study was based on QuEChERS cleanup coupled with UHPLC-MS/MS for the determination of γ-oryzanol compounds in vegetable oils. Several parameters of QuEChERS and UHPLC-MS/MS were studied for purification and detection of γ-oryzanol compounds in oil samples. Under the optimized conditions, the whole pretreatment procedure could be accomplished within 10 min without tedious procedure, larger volume of organic solvent and complicated apparatus. The limit of detections and the limit of quantifications for γ-oryzanol compounds were ranging from 0.1-0.3 µg kg −1 and 0.4–1.0 µg kg −1 , respectively. Satisfactory recoveries of all analyts were ranging from 72.2 % to 101.3 %, and the intra-day and inter-day precision were less than 10.6 %. The validation indicated that rice band oil and corn oil were rich in 24-mCAF, CAF, β-SIF, CMF and STF. The QuEChERS-UHPLC-MS/MS simultaneously quantified five γ-oryzanol compounds in lipid matrices and assessed the nutritional and functional substances of vegetable oils.
研究领域:
食品科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Cotton Research
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2024
·Vol. 7
·期 1
·1-14
·
IF 3.1
Wang Wenhao,Song Xianpeng,Wang Dan,Ma Yajie,Shan Yongpan,Ren Xiangliang,Hu Hongyan,Wu Changcai,Yang Jun,Ma Yan
Background Plant hormones profoundly influence cotton growth, development, and responses to various stresses. Therefore, there is a pressing need for an efficient assay to quantify these hormones in cotton. In this groundbreaking study, we have established QuEChERS-HPLC‒MS/MS method, for the simultaneous detection of multiple plant hormones in cotton leaves, allowing the analysis and quantification of five key plant hormones. Results Sample extraction and purification employed 0.1% acetic acid in methanol and C18 for optimal recovery of plant hormones. The method applied to cotton demonstrated excellent linearity across a concentration range of 0.05–1 mg·L −1 , with linear regression coefficients exceeding 0.99. The limits of quantification (LOQs) were 20 μg·kg −1 for GA 3 and 5 μg·kg −1 for the other four plant hormones. Recovery rates for the five plant hormones matrix spiked at levels of 5, 10, 100, and 1000 μg·kg −1 were in the range of 79.07% to 98.97%, with intraday relative standard deviations (RSDs) ranging from 2.11% to 8.47%. The method was successfully employed to analyze and quantify the five analytes in cotton leaves treated with plant growth regulators. Conclusion The study demonstrates that the method is well-suited for the determination of five plant hormones in cotton. It exhibits excellent selectivity and sensitivity in detecting field samples, thus serving as a robust tool for in-depth research into cotton physiology.
研究领域:
农业化学
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植物生理学
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分析化学
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
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2024
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IF 8.5
Fenglan Zhou,Chunjie Zhou,Wenhua Zhang,Zsolt Zalán,Hui Shi,Jianquan Kan,Kewei Chen,Tian Cai
The detection of mycotoxins in Sichuan peppers is crucial for ensuring food safety. Hence, an efficient detection approach based on the QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) method followed by LC–MS/MS (liquid chromatography–tandem mass spectrometry) was established for the analysis of various mycotoxins in dried red and green Sichuan peppers. Samples were extracted with a solution containing 99 % acetonitrile and 1 % formic acid. A new adsorbent, namely, ENVI-Carb, and primary secondary amines were used as purifying agents. The proposed method demonstrated good linearity (R 2 ≥ 0.999), satisfactory recovery (77.3 %–109.2 %), and good repeatability (intraday and interday relative standard deviations ≤9.7 %) in dried red and green Sichuan peppers. Its limits of detection in red and green Sichuan peppers were 0.2–0.6 and 0.1–0.7 μg/kg, respectively. The established method can effectively eliminate complex matrix interference and provides an effective approach for the high-throughput detection of mycotoxins in various complex food matrices.
研究领域:
食品科学
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分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CyTA-Journal of Food
·
2025
·
IF 1.7
Zhou Lu,Zhao Junpeng,Hilary Kwesi Ketemepi
A QuEChERS-UPLC-MS/MS method was developed and validated for simultaneous determination of six pesticides (chlorpyrifos, malathion, carbofuran, thiodicarb, deltamethrin, and lambda-cyhalothrin) in dairy products. Samples (n=50), collected from a supermarket in Chongqing, China, were extracted with 1% acetic acid–acetonitrile, purified using PSA, and quantified by external-standard UPLC-MS/MS. All pesticides showed excellent linearity (0.001–0.50 mg/L, R² > 0.99), with LOQs of 0.002 mg/kg. Average recoveries at four spiking levels (0.002, 0.01, 0.1, 1.0 mg/kg) ranged from 89% to 110% (RSD 0.5–9.5%, n=5). Analysis of real samples revealed residues below China’s MRLs (GB 2763–2021), confirming regulatory compliance. The method meets analytical requirements for dairy matrices and offers a reliable framework adaptable to other international standards.
研究领域:
食品科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
CEREAL CHEMISTRY
·
2023
·Vol. 100
·期 5
·1106-1113
·
IF 2.4
Yuhang Wan,Xinyu Yuan,Jia Liu,Ding Zhang,Zhengyong Zhang,Min Sha
Background and Objectives Targeting the problems, like various residual pesticides, the high interference of sample matrix and the slow detection speed, this work studied the rapid screening method of multipesticide residues in rice by taking bensulfuron-methyl, propanil and cypermethrin as examples. Findings Rice matrix solution was obtained by using the improved QuEChERS method, matrix standard solution, and solvent standard solution were prepared to obtain the linear range and matrix effect of each pesticide. QuEChERS method could rapidly pretreat samples, and the matrix effect was soft, with matrix effect values lower than 16%. Mixed solutions of the three pesticides in four combinations were prepared within the linear range. The type of pesticides in rice was determined by support vector machine (SVM), and the pesticide concentration was predicted by partial least square regression (PLSR). SVM provided a supervised identification method for pesticide residues, making the recognition accuracy higher than 90%. The error of PLSR in predicting pesticide concentration was lower than 5.36%. Conclusions UV spectroscopy had fast test speed, so the combination of QuEChERS and UV spectroscopy could improve the efficiency of analysis. SVM combined with PLSR could preliminarily determine the type of pesticides in rice sample, and then accurately predict the concentration of pesticides. Significance and Novelty The QuEChERS sample pretreatment technology and UV spectroscopy in combination with chemometrics was expected to be a new technology for rapid detection of pesticide residues in samples.
研究领域:
分析化学
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食品科学
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农学
✓ 已验证
产品关联
DOI
高影响因子
Food Analytical Methods
·
2019
·Vol. 12
·期 7
·1674-1683
·
IF 2.413
Li He,Wu Chun-Jian,Tang Xiang-Yi,Yu Shu-Juan
The 2,3-dihydro-3,5-dihydroxy-6-methyl-4(H)-pyran-4-one (DDMP), 5-hydroxymethylfurfural (HMF), furfural, and 5-methylfurfural (MF) are the components of caramel colors with intense bitterness. In this study, a practical and simple method for the simultaneous analysis of these four bitter compounds in caramel colors and beverages was proposed using high-performance liquid chromatography–diode array detector–atmospheric pressure chemical ionization–mass spectrometry (HPLC-DAD-APCI-MS). For the sample preparation, the extract efficiencies from different extract solvents and quick, easy, cheap, effective, rugged, and safe (QuEChERS) salt pockets were compared. The correlation coefficients ( R 2 ) of all analytical curves were ≥ 0.9914. The satisfactory recoveries ranged between 70.1% and 101.5%, with relative standard deviations ranged from 1.7% to 9.1%. The matrix effect was evaluated, and HMF, furfural, and MF showed signal enrichment. This method was successfully applied to the analysis of bitter compounds content in several caramel colors and beverages from a local market in China. Four compounds were found in eight samples, with concentration ranging from 0.5 to 1058.1 mg kg −1 .
研究领域:
食品科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）