Sirtratumab vedotin (anti-SLITRK6), is an antibody-drug conjugate (ADC) composed of SLTRK6 (SLIT and NTRK like family member 6, "SLIT and NTRK-like family, member 6") and cytotoxic agent monomethyl auristatin E (MMAE). It delivers a small molecule microtubule-disrupting agent, monomethyl auristatin E (MMAE), to tumor cells expressing SLITRK6. Sirtratumab vedotin (anti-SLITRK6) has the potential for Bladder Cancer, Metastatic urothelial cancer research.
规格
产品名称
Sirtratumab vedotin (anti-SLITRK6)
别名
纬斯妥尤单抗
英文别名
SLITRK 6 antibody|Slitrk6 antibody|SLITRK6|MGC119597,4832410J21Rik|SLIT and NTRK-like family, member 6|SLIT and NTRK-like protein 6|slit and trk like gene 6|SLIT and NTRK like family member 6 antibody|SLIT and NTRK like protein 6 antibody|SLIT and NTRK-like protein 6 antibody|Slit and trk like 6 antibody|Slit and trk like gene 6 antibody|DFNMYP antibody|MGC119595 antibody|MGC119596 antibody|MGC119597 antibody|OTTHUMP00000066012 antibody
Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂
No
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
图片
Sirtratumab vedotin (anti-SLITRK6) (Ab183326) - Flow Cytometry Flow Cytometry analysis of HCC1419(ADA009) cells labelling SLITRK6 at 1×105 cell/well can bind Sirtratumab vedotin (anti-SLITRK6) (Ab183326), with the EC50 is 0.020 μg/mL.
Sirtratumab vedotin (anti-SLITRK6) (Ab183326) - SEC The purity of Sirtratumab vedotin (anti-SLITRK6) (Ab183326) is more than 95% verified by HPLC.
高级数据
关联靶点(人)
SLITRK6TbioSLIT 和 NTRK 类蛋白 6(SLIT and NTRK-like protein 6)
(0 活性数据)