丫啶橙半氯化锌盐

CAS: 10127-02-3 货号: A100495 分子式: C₁₇H₂₀ClN₃ · HCl · 1/2ZnCl₂ 分子量: 369.96 Beilstein号: 3734978 EC号: 233-353-6 PubChem CID: 159263

32篇引用文献 COA

有货

级别和纯度: 适用于电泳 ?

别名

碱性橙 14 | 3,6-双(二甲基氨基)吖啶氯化物半(氯化锌盐) | 3,6-双(二甲基氨基)吖啶盐酸盐氯化锌复盐 | 吖啶橙GNY | 吖啶橙3RX

储存条件

2-8°C储存,充氩

运输条件

低温运输

规格

库存

价格

数量

250mg

A100495-250mg

现货

¥32.90

A100495-1g

现货

¥63.90

A100495-5g

现货

¥205.90

25g

A100495-25g

现货

¥528.90

请输入您要添加的产品数量

大包装 / 定制

♡ 收藏夹 ⇅ 比较 ⎙ 打印页面

Skip to the end of the images gallery

Skip to the beginning of the images gallery

概述规格名称和识别符技术文档高级数据系统学分类三维结构质检证书（CoA,COO,BSE/TSE 和分析图谱) 化学和物理性质安全和危险性（GHS）此产品的引用文献技术文档和文章引用文献溶液计算器

🧪

为什么选择此级别

适用于电泳级，适用于对基线干扰要求严格的色谱和分析工作流程。

🌡

储存与运输

2-8°C储存,充氩。低温运输。请查阅批次 COA 获取详细规格。

📋

质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

📚

文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 32 篇同行评审文献引用。

概述

溶于水、乙醇。溶液为橙黄色带绿色荧光。pH值为8.4～10.4则无荧光。能镶嵌于两个相邻的碱基对之间，使部分双螺旋DNA松开，该两个碱基对的距离拉大一倍。这样的DNA复制过程中，会使DNA链增加或缺失一个碱基，造成移码突变。Colour Index Number 46005 用作荧光指示剂，肿瘤细胞及细菌、核酸染色剂及移码突变的诱变剂。吖啶橙是一种荧光色素，吖啶橙激发滤光片波长488nm。阻断滤光片波长515nm。吖啶橙与细胞中DNA和RNA结合量存在差别，可发出不同颜色的荧光（即着色特异性），这是由于DNA是个高度聚合物，吸收荧光物质的位置较少，发绿色荧光，而RNA聚合度低，能和荧光物质结合的位置多，故发红色荧光。

用途

适合

检测凝胶电泳分离的核酸

荧光和落射荧光显微镜

流式细胞术分析线粒体和溶酶体

凋亡研究中的DNA染色

吖啶橙是一种细胞可渗透的异染色荧光阳离子染料，可嵌入 DNA 和 RNA，用于荧光和表观显微镜检测。吖啶橙染料已被用于通过流式细胞术分析线粒体和溶酶体含量，表征多药耐药性以及检测大鼠胸腺细胞凋亡过程中线粒体质量的变化。

Acridine Orange hemi (zinc chloride) salt is a cell-permeable metachromatic fluorescent dye that stains DNA and RNA. This dye is also an inhibitor of RNA polymerase.
Fluorescent dye that stains DNA and RNA

Application

Suitable for

detection of nucleic acids separated by gel electrophoresis

fluorescence and epifluorescence microscopy

analysis of mitochondria and lysosomes by flow cytometry

DNA staining in apoptosis studies

Acridine Orange, a cell-permeable metachromatic fluorescent cationic dye that intercalates DNA and RNA, is used in fluorescence and epiflouresence microscopy. Acridine Orange dye has been used to analyze mitochondria and lysosomal content by flow cytometry, characterize multidrug resistance, and measure changes in mitochondrial mass during apoptosis in rat thymocytes.

规格

别名

碱性橙 14 | 3,6-双(二甲基氨基)吖啶氯化物半(氯化锌盐) | 3,6-双(二甲基氨基)吖啶盐酸盐氯化锌复盐 | 吖啶橙GNY | 吖啶橙3RX

英文别名

规格或纯度

用于电泳

英文名称

Acridine Orange hemi(zinc chloride) salt

生化机理

可渗透细胞的变色荧光阳离子染料，可染色DNA和RNA。也是RNA聚合酶的抑制剂。

储存条件

2-8°C储存,充氩

运输条件

低温运输

备注

如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。有毒，请参阅SDS以获取更多信息。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

名称和识别符

PubChem SID

508811736

EC号

233-353-6

分子类型

小分子

IUPAC Name

zinc;3-N,3-N,6-N,6-N-tetramethylacridine-3,6-diamine;dichloride;hydrochloride

INCHI

1S/C17H19N3.3ClH.Zn/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;;;;/h5-11H,1-4H3;3*1H;/q;;;;+2/p-2

InChi Key

VADJQOXWNSPOQA-UHFFFAOYSA-L

Smiles

CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl.[Cl-].[Cl-].[Zn+2]

Isomeric SMILES

CN(C)C1=CC2=C(C=C1)C=C3C=CC(=CC3=N2)N(C)C.Cl.[Cl-].[Cl-].[Zn+2]

PubChem CID

159263

分子量

369.96

Beilstein号

3734978

Reaxy-Rn

10510633

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

系统学分类

分类树（Taxonomy Tree）

界（kingdom) 有机化合物
- 超类（Superclass) 有机杂环化合物
  - 类（Class) 喹啉及其衍生物
    - 亚类（Subclass）苯并喹啉

界（kingdom)	有机化合物
超类（Superclass)	有机杂环化合物
类（Class)	喹啉及其衍生物
亚类（Subclass）	苯并喹啉
中间层级节点（Intermediate Tree Nodes）	暂无
直接上位类(Direct Parent)	吖啶类
其他上位类（Alternative Parents）	氨基喹啉及其衍生物二烷基芳胺吡啶及其衍生物苯类化合物杂芳族化合物有机过渡金属盐有机金属卤化物氮杂环化合物有机光子化合物有机氯化物盐盐酸盐碳氢化合物衍生物
分子骨架（Molecular Framework)	芳香族杂多环化合物
取代基（Substituents）	萘醌 - 氨基酸 - 氨基吡啶 - 芳香族杂多环化合物 - 氮杂环 - 苯基化合物 - 二烷基芳基胺 - 杂芳香族化合物 - 烃衍生物 - 氟氯烃 - 有机氯酸盐 - 有机金属卤化物 - 有机硝基化合物 - 有机盐 - 有机过氧化物 - 有机氮化合物 - 有机氮化合物 - 吡啶 - 三级脂肪族/芳香族胺 - 三芳基胺
描述（Description）	该化合物属于有机化合物中的萘啶类。这类化合物含有萘啶结构单元——一种由两个苯环经吡啶环连接而成的线性三环杂环。
外部描述符（External Descriptors）	暂无

三维结构

交互式化学结构模型

球棍
棍棒
线框模型
空间填充
显示氢气
动画

化学和物理性质

溶解性

Soluble in water (1 mg/ml).

密度

2.54

敏感性

对湿度敏感

分子量

438.100 g/mol

XLogP3

氢键供体数Hydrogen Bond Donor Count

氢键受体数Hydrogen Bond Acceptor Count

可旋转键计数Rotatable Bond Count

精确质量Exact Mass

435.001 Da

单同位素质量Monoisotopic Mass

435.001 Da

拓扑极表面积Topological Polar Surface Area

19.400 Å²

重原子数Heavy Atom Count

形式电荷Formal Charge

复杂度Complexity

298.000

同位素原子数Isotope Atom Count

定义的原子立体中心计数Defined Atom Stereocenter Count

未定义的原子立体中心计数Undefined Atom Stereocenter Count

定义的键立体中心计数Defined Bond Stereocenter Count

未定义的键立体中心计数Undefined Bond Stereocenter Count

所有立体化学键的总数The total count of all stereochemical bonds

共价键合单元计数Covalently-Bonded Unit Count

安全和危险性（GHS）

象形图

GHS08

信号词

警告

危险声明

H341: 怀疑引起遗传缺陷

预防措施声明

P281: 根据需要使用个人防护设备。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P203: 使用前，获取、阅读并遵守所有安全说明。

P318: 如果暴露或担心，请就医。

WGK Germany

个人防护装备

Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！

找到9个结果

批号(Lot Number)	证书类型	货号
I2205456	分析证书	A100495
G2216055	分析证书	A100495
G2216079	分析证书	A100495
I2108064	分析证书	A100495
F2124018	分析证书	A100495
F1529001	分析证书	A100495
F2509044	分析证书	A100495
H2507150	分析证书	A100495
F2207282	分析证书	A100495

技术文档和文章

细胞核染料的类型、结合机制与实验选型

目录：技术文章

探索主题:

流式细胞术细胞周期 DAPI 荧光显微镜活死细胞染色 Hoechst 苏木精甲基绿 DRAQ5 细胞核染料 PI 7-AAD SYTO 吖啶橙核固红

Types, Binding Mechanisms, and Experimental Selection of Nuclear Dyes

目录：技术文章

探索主题:

DAPI Hoechst PI nuclear dye 7-AAD

血液寄生虫显微检测：厚血膜、薄血膜制片与Romanowsky类染色体系

目录：技术文章

探索主题:

血液寄生虫厚血膜薄血膜 Giemsa染色 Wright-Giemsa染色疟原虫巴贝虫微丝蚴

Microscopic Detection of Blood Parasites: Thick and Thin Blood Film Preparation and Romanowsky-Type Staining Systems

目录：技术文章

探索主题:

Giemsa Staining Wright-Giemsa staining Blood Parasites Thick Blood Film Thin Blood Film Plasmodium Babesia Microfilariae

此产品的引用文献

如何在您的发表作品中引用阿拉丁的产品和网站? 引用文献检索

引用文献

1. Zhiwen Shen, Mingli Tian, Faxiang Wang, Yongle Liu, Jinhong Wu, Xianghong Li. (2023) Enhancing freeze-thaw stability and flavor in surimi products: Impact of virgin coconut oil and fish oil incorporation. Food Bioscience, [10.1016/j.fbio.2023.103515]
2. Zhiwen Shen, Huaqian Gao, Wanqi Peng, Faxiang Wang, Yongle Liu, Jinhong Wu, Shaoyun Wang, Xianghong Li. (2023) Cryoprotective effect of soybean oil on surimi gels and the mechanism based on molecular dynamics simulation. JOURNAL OF TEXTURE STUDIES, [PMID:37968073] [10.1111/jtxs.12812]
3. Xi Chen, Chenyao Tian, Hao Zhang, Hui Xie. (2023) Biodegradable Magnetic Hydrogel Robot with Multimodal Locomotion for Targeted Cargo Delivery. ACS Applied Materials & Interfaces, [PMID:37283440] [10.1021/acsami.3c02703]
4. Hua-Jie Wang, Meng-Fei Hao, Guan Wang, Hao Peng, Fazli Wahid, Yan Yang, Lei Liang, Shan-Qin Liu, Ren-Long Li, Shu-Ying Feng. (2023) Zein nanospheres assisting inorganic and organic drug combination to overcome stent implantation-induced thrombosis and infection. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:36842591] [10.1016/j.scitotenv.2023.162438]
5. Tianyi Chen, Haoze Chen, Anli Wang, Weixuan Yao, Zhongshi Xu, Binjie Wang, Jiye Wang, Yuanzhao Wu. (2023) Methyl Parathion Exposure Induces Development Toxicity and Cardiotoxicity in Zebrafish Embryos. Toxics, 11 (1): (84). [PMID:36668810] [10.3390/toxics11010084]
6. Yu Zhang, Dekun Cheng, Zhangtie Wang, Yiwen Guo, Ming Chang, Ruijie Liu. (2022) Protective Effect of Orbitides from Linseed (Linum usitatissimum L.) against Ultraviolet B-induced Photoaging in Zebrafish. PHOTOCHEMISTRY AND PHOTOBIOLOGY, [PMID:36484266] [10.1111/php.13758]
7. Xi Chen, Hao Zhang, Chenyao Tian, Jingzhi Jia, Hui Xie. (2022) Multiscale Magnetic Hydrogel Robot with a Core–Shell Structure for Active Targeted Delivery. ACS Applied Polymer Materials, [10.1021/acsapm.2c01555]
8. Miaoqi Dai, Xiong Xiong, Anwei Cheng, Zhengtao Zhao, Qian Xiao. (2022) Development of pullulan-based nanocomposite films reinforced with starch nanocrystals for the preservation of fresh beef. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 103 (4): (1981-1993). [PMID:36260277] [10.1002/jsfa.12280]
9. Jiao Yang Lu, Xiaolong Zhou, Jialiang Yang, Yi Zhou, Binsheng He, Wei Tao Huang, Yajing Wang, Zhen Guo. (2022) Migration inhibition and selective cytotoxicity of cobalt hydroxide nanosheets on different cancer cell lines. NEW JOURNAL OF CHEMISTRY, 46 (21): (10289-10298). [10.1039/D2NJ01466A]
10. Qing Yu Liu, Zhen Qi Bu, Qing Feng Yao, Xuezhi Ding, Li Qiu Xia, Wei Tao Huang. (2021) Microwave-Assisted Synthesis of Chromium Oxide Nanoparticles for Fluorescence Biosensing of Mercury Ions and Molecular Logic Computing. ACS Applied Nano Materials, [10.1021/acsanm.1c01102]
11. Zhenglu Wang, Shuiping Dai, Jinze Wang, Wei Du, Lin Zhu. (2021) Assessment on chronic and transgenerational toxicity of methamphetamine to Caenorhabditis elegans and associated aquatic risk through toxicity indicator sensitivity distribution (TISD) analysis. ENVIRONMENTAL POLLUTION, [PMID:34243081] [10.1016/j.envpol.2021.117696]
12. Qi Liu, Yi Luo, Yun Zhao, Pingping Xiang, Jinyun Zhu, Wangwei Jing, Wenjing Jin, Mingyao Chen, Ruikang Tang, Hong Yu. (2021) Nano-hydroxyapatite accelerates vascular calcification via lysosome impairment and autophagy dysfunction in smooth muscle cells. Bioactive Materials, [PMID:34541414] [10.1016/j.bioactmat.2021.06.004]
13. Zhaohui Chen, Shuihua Wu. (2020) Protective Effects of SIRT6 Against Inflammation, Oxidative Stress, and Cell Apoptosis in Spinal Cord Injury. INFLAMMATION, 43 (5): (1751-1758). [PMID:32445068] [10.1007/s10753-020-01249-2]
14. Leipu Zhao, Cui Du, Chen Zhou, Shasha Sun, Yuanzheng Jia, Jiasheng Yuan, Guangming Song, Xin Zhou, Qian Zhao, Shengyang Yang. (2020) Structurally Ordered AgNPs@C3N4/GO Membranes toward Solar-Driven Freshwater Generation. ACS Sustainable Chemistry & Engineering, [10.1021/acssuschemeng.9b06603]
15. Zeng Xin, Zhu Min, Liu Xiaohong, Chen Xuanmin, Yuan Yujia, Li Lan, Liu Jingping, Lu Yanrong, Cheng Jingqiu, Chen Younan. (2020) Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis. Nutrition & Metabolism, 17 (1): (1-14). [PMID:32021639] [10.1186/s12986-020-0434-8]
16. Zhigang Guo, Hu Guozhang, Hang Wang, Zhaohui Li, Naijie Liu. (2019) Ampelopsin inhibits human glioma through inducing apoptosis and autophagy dependent on ROS generation and JNK pathway. BIOMEDICINE & PHARMACOTHERAPY, [PMID:31108349] [10.1016/j.biopha.2018.12.136]
17. Zhenqiang Wang, Liucan Wang, Neeraj Prabhakar, Yuxin Xing, Jessica M. Rosenholm, Jixi Zhang, Kaiyong Cai. (2019) CaP coated mesoporous polydopamine nanoparticles with responsive membrane permeation ability for combined photothermal and siRNA therapy. Acta Biomaterialia, [PMID:30611792] [10.1016/j.actbio.2019.01.002]
18. Nan Fang Nie, Xin Xing Zhang, Chu Shan Fang, Qiu Yan Zhu, Jiao Yang Lu, Fu Rui Zhang, Qing Feng Yao, Wei Tao Huang, Xue Zhi Ding, Li Qiu Xia. (2018) Game Theory in Molecular Nanosensing System for Rapid Detection of Hg2+ in Aqueous Solutions. Applied Sciences-Basel, 8 (12): (2530). [10.3390/app8122530]
19. Lin Xi, Yan Shu-Zhen, Qi Shan-Shan, Xu Qiao, Han Shuang-Shuang, Guo Ling-Yuan, Zhao Ning, Chen Shuang-Lin, Yu Shu-Qin. (2017) Transferrin-Modified Nanoparticles for Photodynamic Therapy Enhance the Antitumor Efficacy of Hypocrellin A. Frontiers in Pharmacology, [PMID:29209206] [10.3389/fphar.2017.00815]
20. Huan Wang, Ping Zhang, Jing Liu. (2017) Triethylene Tetramine Functionalized Magnetic Graphene Oxide Chitosan Composite with Superior Capacity for the Removal of Phosphate. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [10.1021/acs.jced.7b00417]
21. Huanan Wang, Wenqing Xu. (2017) Mito-methyl coumarin, a novel mitochondria-targeted drug with great antitumor potential was synthesized. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, [PMID:28546001] [10.1016/j.bbrc.2017.05.116]
22. Lin Zhou, Yingzhen Lai, Wenxiu Huang, Sijia Huang, Zhiqiang Xu, Jiang Chen, Dong Wu. (2015) Biofunctionalization of microgroove titanium surfaces with an antimicrobial peptide to enhance their bactericidal activity and cytocompatibility. COLLOIDS AND SURFACES B-BIOINTERFACES, [PMID:25800357] [10.1016/j.colsurfb.2015.03.008]
23. Xue-Li Cao, Tian Tian, Yong Bai, Chun Cui, Cong Luo, Jiang-Shan Xing, Chuan-Yu Chen, Lili Zhao, Shi-Peng Sun. (2024) Broad-spectrum corrosion-resistant nanofiltration membranes via reactive site-bridged nanofibrous network. AICHE JOURNAL, [10.1002/aic.18699]
24. Ce Chen, Lidong Yu, Xueting Li, Zewen Yu, Danjie Song, Siqi Wang, Fangshun Li, Shanshan Jiang, Yajie Chen, Jucai Xu, Jianglin Fan, Bingsheng Li, Li Li. (2024) Reducing Oxidative Stress Levels and Inhibiting Aging by l-Cysteine-Derived Carbon Dots with Highly Efficient Broad-Spectrum UV Absorption. ACS Applied Materials & Interfaces, [PMID:39121011] [10.1021/acsami.4c02955]
25. Lin Mei, Zhimin Liu, Yanmei Shi, Xiangyun Zhang. (2024) Stable and biocompatible multivalent polymer-grafted gold nanorods for enhanced photothermal antibacterial therapy. JOURNAL OF APPLIED POLYMER SCIENCE, [10.1002/app.56230]
26. Shaohua Liu, Chen Wang, Chaoran Wang, Yuanyuan Deng, Yanping Tang, Boshi Tian, Hongjun Xia, Yahong Chen, Lin Jin, Zhengxiao Guo, Piaoping Yang. (2025) A biodegradable self-cascading copper-based nanozyme for augmented cancer catalytic therapy and cuproptosis. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:40829233] [10.1016/j.jcis.2025.138692]
27. Yi-Ming Zhao, Lin Zhang, Yulong Bao, Yiting Guo, Haile Ma, Ronghai He, Paula Bourke, Da-Wen Sun. (2025) The inhibitory mechanisms of plasma-activated water on biofilm formation of Pseudomonas fluorescens by disrupting quorum sensing. FOOD RESEARCH INTERNATIONAL, [PMID:41214946] [10.1016/j.foodres.2025.117436]
28. Liu Xiaozhen, Hao Jiao, Yuan Youyuan, Liu Fang. (2025) Synergic chemotherapeutic effects of docetaxel and carboplatin show cytotoxic and apoptotic effects in liver cancer nursing care: Role of oxidative stress and hemocompatibility. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, [PMID:40434421] [10.1007/s00210-025-04295-5]
29. Kun Yan, Zongrun Zhang, Xianzhu Yang, Chenguang Yang, Zhentan Lu, Dong Wang. (2025) Glycosylation-Engineered Chitosan Bioelectronic Interfaces for P. aeruginosa Gradient Analysis. ANALYTICAL CHEMISTRY, [PMID:40570237] [10.1021/acs.analchem.5c01313]
30. Meng Yao Wu, Yu Qing Tian, Jiao Yang Lu, Tian Tian Fu, Hou Cheng Liang, Wei Tao Huang. (2025) Synthesis of Sustainable Chromium-Based Nanoparticles With Fluorescence Tunable Ability for Biosensing of Tumor-Derived Exosomes and Molecular Information Protection. SusMat, [10.1002/sus2.70053]
31. Yifan Wang, Hedi Zhao, Gangqiang Dong, Dan Yang, Xiaofei Liu, Zhuyin Chen, Yanyan Su, Yan Liu, Jingjing Zhu, Jun Zhang, Jing Zhang, Sha Chen. (2026) Integrated metabolomics and bioactivity analysis of new chrysanthemum cultivar petals: Insights into eye-protecting agents. PLoS One, 21 (2): (e0340052). [PMID:41662364] [10.1371/journal.pone.0340052]
32. Xi Jiang, Fengqi Yang, Huiling Gong, Yanfei Mou, Junyi An, Lei Wang, Xiaona Wang, Zhenzhen Zhang, Xiao Wei, Li Sun, Wenli Wang, Fenglei Cao, Yang Zhao, Ding Qu. (2026) Sustained Retinal Delivery of Baicalin and Ranibizumab Overcomes the Anti-VEGF Monotherapy Dilemma in wAMD. Small, [PMID:42504692] [10.1002/smll.74813]