H2617010计算溶液所需的质量、体积或浓度。
| 活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
|---|
有货
为什么选择此级别
Moligand™ 级 提供 ≥90%(HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-20°C储存。超低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 26 篇同行评审文献引用。
概述
Morin 是一种植物性黄酮类化合物，具有较低的抗氧化活性。Morin 是一种用于铝物种形成的荧光螯合剂。
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate.
规格
别名
2',3,4',5,7-五羟黄酮
英文别名
Flavone,3,4',5,7-pentahydroxy- | KBio1_000958 | s10675 | cid_5281670 | NCGC00015672-09 | 2',4',5, 7-Tetrahydroxyflavan-3-ol | 8NFQ3F76WR | AI3-38057 | C.I. 75660 | CHEBI:75092 | Spectrum2_000715 | 2',3,5,7-Pentahydroxyflavone | 3,5,7,2',4'-Pentahydroxyfla
规格或纯度
Moligand™, ≥90%(HPLC)
英文名称
Aluminum Ionophore I
储存条件
-20°C储存
运输条件
超低温运输
作用类型
拮抗剂
作用机制
A 1 受体拮抗剂；A 2A 受体拮抗剂
纯度
≥90%(HPLC)
名称和识别符
PubChem SID
EC号
207-542-9
分子类型
小分子
IUPAC Name
2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
INCHI
1S/C15H10O7/c16-6-1-2-8(9(18)3-6)15-14(21)13(20)12-10(19)4-7(17)5-11(12)22-15/h1-5,16-19,21H
InChi Key
YXOLAZRVSSWPPT-UHFFFAOYSA-N
Smiles
C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
Isomeric SMILES
C1=CC(=C(C=C1O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
分子量
302.24
Reaxy-Rn
327474
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=327474&ln=
技术文档
高级数据
系统学分类
分类树（Taxonomy Tree）
| 界（kingdom) | 有机化合物 |
|---|---|
| 超类（Superclass) | 苯丙素类和聚酮类 |
| 类（Class) | 黄酮类化合物 |
| 亚类（Subclass） | 黄酮类 |
| 中间层级节点（Intermediate Tree Nodes） | 暂无 |
| 直接上位类(Direct Parent) | 黄酮醇 |
| 其他上位类（Alternative Parents） | 3-羟基黄酮类化合物 4'-羟基黄酮类化合物 5-羟基黄酮类化合物 7-羟基黄酮类化合物 色酮 间苯二酚 1-羟基-2-未取代苯类化合物 吡喃酮及其衍生物 1-羟基-4-未取代苯类化合物 苯及其取代衍生物 乙烯基酸 杂芳族化合物 氧环化合物 多元醇 有机氧化物 碳氢化合物衍生物 |
| 分子骨架（Molecular Framework) | 芳香族杂多环化合物 |
| 取代基（Substituents） | 1-苯并吡喃 - 1-羟基-2-未取代苯环化合物 - 1-羟基-4-未取代苯环化合物 - 3-羟基黄酮 - 3-羟基黄酮 - 4'-羟基黄酮 - 5-羟基黄酮 - 7-羟基黄酮 - 芳香族杂多环化合物 - 苯基化合物 - 苯并吡喃 - 苯并吡喃 - 杂芳香族化合物 - 烃衍生物 - 羟基黄酮 - 单环苯基基团 - 有机氧化物 - 有机氧化合物 - 有机杂环化合物 - 有机氧化合物 - 氧杂环 - 苯酚 - 多醇 - 吡喃 - 吡喃酮 - 间苯二酚 - 乙烯基羧酸 |
| 描述（Description） | 该化合物属于黄酮醇类有机化合物。这类化合物以黄酮（2-苯基-1-苯并吡喃-4-酮）为骨架，其3位带有羟基。 |
| 外部描述符（External Descriptors） | Flavones and Flavonols |
三维结构
交互式化学结构模型
关联靶点（人）
ADORA2A
Tclin
腺苷受体A2a(Adenosine receptor A2a)
(1 活性数据)
ADORA1
Tclin
腺苷受体A1(Adenosine receptor A1)
(1 活性数据)
PRSS1
Tclin
Trypsin I
(2306 活性数据)
CHRM1
Tclin
Muscarinic acetylcholine receptor M1
(12690 活性数据)
TOP2A
Tclin
DNA topoisomerase II alpha
(6317 活性数据)
DRD1
Tclin
Dopamine D1 receptor
(9720 活性数据)
ACHE
Tclin
Acetylcholinesterase
(18204 活性数据)
ADORA1
Tclin
Adenosine A1 receptor
(17603 活性数据)
XDH
Tclin
Xanthine dehydrogenase
(1038 活性数据)
KCNH2
Tclin
HERG
(29587 活性数据)
ESR2
Tclin
Estrogen receptor beta
(9272 活性数据)
ADORA3
Tchem
Adenosine A3 receptor
(15931 活性数据)
POLB
Tchem
DNA polymerase beta
(23632 活性数据)
CASP8
Tchem
Caspase-8
(1006 活性数据)
APP
Tclin
Amyloid-beta A4 protein
(8510 活性数据)
PIM1
Tchem
Serine/threonine-protein kinase PIM1
(9629 活性数据)
SYK
Tclin
Tyrosine-protein kinase SYK
(7372 活性数据)
PLK1
Tchem
Serine/threonine-protein kinase PLK1
(28605 活性数据)
GAA
Tclin
Lysosomal alpha-glucosidase
(35701 活性数据)
ALDH1A1
Tchem
Aldehyde dehydrogenase 1A1
(77053 活性数据)
DAPK1
Tchem
Death-associated protein kinase 1
(1664 活性数据)
FBP1
Tchem
Fructose-1,6-bisphosphatase
(1199 活性数据)
NFKB1
Tclin
Nuclear factor NF-kappa-B p105 subunit
(1459 活性数据)
FASN
Tchem
Fatty acid synthase
(3390 活性数据)
CASP1
Tchem
Caspase-1
(6235 活性数据)
ALOX15
Tchem
Arachidonate 15-lipoxygenase
(7108 活性数据)
CASP7
Tchem
Caspase-7
(3146 活性数据)
BACE1
Tchem
Beta-secretase 1
(15641 活性数据)
PDK1
Tchem
Pyruvate dehydrogenase kinase isoform 1
(2021 活性数据)
PIN1
Tchem
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
(36611 活性数据)
CYP2C9
Tchem
Cytochrome P450 2C9
(32119 活性数据)
CYP3A4
Tclin
Cytochrome P450 3A4
(53859 活性数据)
YES1
Tclin
Tyrosine-protein kinase YES
(2781 活性数据)
TP53
Tchem
Cellular tumor antigen p53
(48468 活性数据)
ACHN
(49357 活性数据)
CAKI-1
(44928 活性数据)
CCRF-CEM
(65223 活性数据)
COLO 205
(50209 活性数据)
DU-145
(51482 活性数据)
HL-60
(67320 活性数据)
HT-29
(80576 活性数据)
K562
(73714 活性数据)
KM12
(47707 活性数据)
M14
(47487 活性数据)
MCF7
(126967 活性数据)
OVCAR-3
(48710 活性数据)
OVCAR-4
(44535 活性数据)
OVCAR-5
(45555 活性数据)
OVCAR-8
(47708 活性数据)
PC-3
(62116 活性数据)
SF-295
(48000 活性数据)
SK-MEL-2
(46422 活性数据)
关联靶点（其它种属）
Glo1
Glyoxalase I (4 活性数据)
polC
DNA polymerase III (243 活性数据)
Abcc1
Multidrug resistance-associated protein 1 (42 活性数据)
Abcb1b
P-glycoprotein 1 (174 活性数据)
Hdac6
Histone deacetylase 6 (222 活性数据)
pol
Human immunodeficiency virus type 1 integrase (9041 活性数据)
MAL62
Alpha-glucosidase MAL62 (106 活性数据)
Pseudomonas aeruginosa (123386 活性数据)
Salmonella typhimurium (15756 活性数据)
Staphylococcus aureus (210822 活性数据)
Escherichia coli (133304 活性数据)
Proteus mirabilis (3894 活性数据)
Saccharomyces cerevisiae (19171 活性数据)
Plasmodium falciparum (966862 活性数据)
Human immunodeficiency virus 1 (70413 活性数据)
Hepatitis C virus (23859 活性数据)
CCRF S-180 (1031 活性数据)
L1210 (27553 活性数据)
P388 (20296 活性数据)
L929 (3802 活性数据)
fabG
3-oxoacyl-acyl-carrier protein reductase (70 活性数据)
fabI
Enoyl-acyl-carrier protein reductase (415 活性数据)
Avian myoblastosis virus polyprotein II (68 活性数据)
GCN5
Histone acetyltransferase GCN5 (89 活性数据)
srtA
Sortase A (641 活性数据)
rep
Replicase polyprotein 1ab (378 活性数据)
PYK
Pyruvate kinase (6726 活性数据)
pfk
6-phospho-1-fructokinase (7870 活性数据)
Txnrd1
Thioredoxin reductase 1, cytoplasmic (45279 活性数据)
BCHE
Cholinesterase (8742 活性数据)
Mapt
Microtubule-associated protein tau (6 活性数据)
nfo
Endonuclease 4 (425 活性数据)
PNLIP
Pancreatic triacylglycerol lipase (476 活性数据)
Phosphoglycerate kinase, glycosomal (2184 活性数据)
E6
Protein E6 (25 活性数据)
Adora2b
Adenosine A2 receptor (1828 活性数据)
TUBB2B
Tubulin (2175 活性数据)
groL
GroEL/GroES (1042 活性数据)
groEL
60 kDa chaperonin (64 活性数据)
SARS-CoV-2 (38078 活性数据)
作用机制
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
化学和物理性质
分子量
302.230 g/mol
XLogP3
1.500
氢键供体数Hydrogen Bond Donor Count
5
氢键受体数Hydrogen Bond Acceptor Count
7
可旋转键计数Rotatable Bond Count
1
精确质量Exact Mass
302.043 Da
单同位素质量Monoisotopic Mass
302.043 Da
拓扑极表面积Topological Polar Surface Area
127.000 Ų
重原子数Heavy Atom Count
22
形式电荷Formal Charge
0
复杂度Complexity
488.000
同位素原子数Isotope Atom Count
0
定义的原子立体中心计数Defined Atom Stereocenter Count
0
未定义的原子立体中心计数Undefined Atom Stereocenter Count
0
定义的键立体中心计数Defined Bond Stereocenter Count
0
未定义的键立体中心计数Undefined Bond Stereocenter Count
0
所有立体化学键的总数The total count of all stereochemical bonds
0
共价键合单元计数Covalently-Bonded Unit Count
1
安全和危险性（GHS）
象形图
信号词
警告
危险声明
H315: 引起皮肤刺激
H319: 引起严重眼睛刺激
H335: 可能引起呼吸道刺激
预防措施声明
P261: 避免吸入灰尘/烟雾/气体/雾/蒸汽/喷雾
P264: 处理后要彻底洗手。
P271: 仅在室外或通风良好的地方使用。
P280: 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302+P352: 如皮肤沾染：用水充分清洗。
P304+P340: 如误吸入：将人转移到空气新鲜处，保持呼吸舒适体位。
P305+P351+P338: 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P405: 密闭存放
P403+P233: 存放在通风良好的地方。保持容器密闭。
P337+P317: 如果眼睛刺激持续：寻求医疗帮助。
P332+P317: 如果出现皮肤刺激：请寻求医疗帮助。
P319: 如果你感到不适，请寻求医疗帮助。
质检证书（CoA,COO,BSE/TSE 和分析图谱)
此产品的引用文献
引用文献
| 1. Tian Yang, Zhong Zhang, Fangjian Ning, Li Yuan, Xingbin Yang, Liping Luo. (2023) New theoretical perspective for easy evaluation of the antioxidant properties of typical flavonoids. MICROCHEMICAL JOURNAL, [10.1016/j.microc.2023.109786] |
| 2. Qing Li, Run Lu, Huiyu Jiang, Yuyang Zhou. (2023) Efficient and sustainable bleaching of cotton/spandex integrating UVA radiation and peroxide activator: A study focus on the degradation mechanism of natural pigments in fibres. Arabian Journal of Chemistry, [10.1016/j.arabjc.2023.105348] |
| 3. Xiaodan Tang, Yichao Zhao, Hongmei Yu, Shuanping Cui, Hunter Temple, Eric Amador, Yun Gao, Ming-li Chen, Shaoyan Wang, Zhizhi Hu, Wei Chen. (2023) Concentration-regulated multi-color fluorescent carbon dots for the detection of rifampicin, morin and Al3+. Materials Today Advances, [10.1016/j.mtadv.2023.100383] |
| 4. Heng Ye, Gang Wang, Xuchao Wang, Lin Wang, Wei Ni, Linjian Chen, Yifan Zhu, Longshan Zhao, Zhili Xiong, Yan Wang, Cuilian Dai, Binbin Liu. (2023) San-wei-tan-xiang capsule attenuates atherosclerosis by increasing lysosomal activity in adipose tissue macrophages. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:37061068] [10.1016/j.jep.2023.116444] |
| 5. Rongqian Meng, Yanfeng Xue, Lijun Guo, Hong Yang, Yongbo Song, Qiaoling Li, Yulan Niu. (2022) Overoxidized polypyrrole/overoxidized poly(3,4-ethylenedioxythiophene)/graphene quantum dots-chitosan as enhanced electrochemical sensing platform for luteolin determination in peanut shells. NEW JOURNAL OF CHEMISTRY, 46 (43): (20610-20622). [10.1039/D2NJ03738F] |
| 6. Qing Li, Run Lu, Yan Liang, Kang Gao, Huiyu Jiang. (2022) Energy-Saving One-Step Pre-Treatment Using an Activated Sodium Percarbonate System and Its Bleaching Mechanism for Cotton Fabric. Materials, 15 (17): (5849). [PMID:36079230] [10.3390/ma15175849] |
| 7. Yumin Hao, Wenjuan Dong, Yang Liu, Xiaole Wen, Shaomin Shuang, Qin Hu, Chuan Dong, Xiaojuan Gong. (2022) Nitrogen-doped carbon dots coupled with morin-Al3+: Cleverly design an integrated sensing platform for ratiometric optical dual-mode and smartphone-assisted visual detection of fluoride ion. JOURNAL OF HAZARDOUS MATERIALS, [PMID:35863221] [10.1016/j.jhazmat.2022.129596] |
| 8. Siyuan Tang, Xiameng Li, Changxing Wang, Tingting Li, Guoqiang Guo, Yiru Wang, Da Chen. (2022) Target-oriented synthesis of high synthetic yield carbon dots by waxberry for optical dual-mode and smartphone imaging detection of morin. MATERIALS LETTERS, [10.1016/j.matlet.2022.132673] |
| 9. Rongqian Meng, Jianke Tang, Xiaojun Wu, Shengjian Zhang, Xin Wang, Qiaoling Li, Riya Jin. (2021) Molecularly Imprinted Electrochemical Sensor Based on 3D Wormlike PEDOT-PPy Polymer for the Sensitive Determination of Rutin in Flos Sophorae Immaturus. JOURNAL OF THE ELECTROCHEMICAL SOCIETY, 168 (7): (077521). [10.1149/1945-7111/ac0f8a] |
| 10. Guangqian Yang, Zhengyi Liu, Tingting Lan, Li Dou, Kankan Zhang. (2021) Potential enantioselectivity of the hydrolysation and photolysation of the chiral agrochemical penthiopyrad in aquatic environments. Environmental Science-Water Research & Technology, 7 (7): (1220-1229). [10.1039/D1EW00098E] |
| 11. Yanan Yan, Lin Li, Huilin Zhang, Fangfang Du, Yating Meng, Shaomin Shuang, Ruibing Wang, Shengmei Song, Chuan Dong. (2021) Carbon dots for ratiometric fluorescence detection of morin. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:33819765] [10.1016/j.saa.2021.119751] |
| 12. Xueqing Guo, Yang Liu, Wenjuan Dong, Qin Hu, Yong Li, Shaomin Shuang, Chuan Dong, Lishuai Cai, Xiaojuan Gong. (2021) Azithromycin detection in cells and tablets by N,S co-doped carbon quantum dots. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:33561684] [10.1016/j.saa.2021.119506] |
| 13. Zhixia Yao, Hanmeng Liu, Yaosheng Liu, Yongxing Diao, Guangxing Hu, Qifang Zhang, Zhuang Li. (2020) FRET-based fluorometry assay for curcumin detecting using PVP-templated Cu NCs. TALANTA, [PMID:33298267] [10.1016/j.talanta.2020.121741] |
| 14. Shuqian Yu, Yanshuai Cui, Xiaolei Guo, Shengfu Chen, Haotian Sun, Longgang Wang, Jing Wang, Yu Zhao, Zhiwei Liu. (2019) Biocompatible bovine serum albumin stabilized platinum nanoparticles for the oxidation of morin. NEW JOURNAL OF CHEMISTRY, 43 (22): (8774-8780). [10.1039/C9NJ00887J] |
| 15. Meihui Fan, Huafang Ding, Guowen Zhang, Xing Hu, Deming Gong. (2019) Relationships of dietary flavonoid structure with its tyrosinase inhibitory activity and affinity. LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2019.02.076] |
| 16. Longgang Wang, Jin Zhang, Xiaolei Guo, Shengfu Chen, Yanshuai Cui, Qingyu Yu, Lubin Yang, Haotian Sun, Dawei Gao, Danyang Xie. (2018) Highly stable and biocompatible zwitterionic dendrimer-encapsulated palladium nanoparticles that maintain their catalytic activity in bacterial solution. NEW JOURNAL OF CHEMISTRY, 42 (24): (19740-19748). [10.1039/C8NJ04263B] |
| 17. Wang Qianqian, Xu Yixiang, Xu Jiaqi, Wang Xudong, Shen Chen, Zhang Yan, Liu Xiufeng, Yu Boyang, Zhang Jian. (2017) Molecular cloning and expression of a glycosyltransferase from Bacillus subtilis for modification of morin and related polyphenols. BIOTECHNOLOGY LETTERS, 39 (8): (1229-1235). [PMID:28484911] [10.1007/s10529-017-2352-z] |
| 18. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
| 19. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2016) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, [PMID:28159264] [10.1016/j.foodchem.2016.12.001] |
| 20. Depeng Kong, Fanyong Yan, Yunmei Luo, Qianghua Ye, Siyushan Zhou, Li Chen. (2016) Amphiphilic carbon dots for sensitive detection, intracellular imaging of Al3+. ANALYTICA CHIMICA ACTA, [PMID:28010744] [10.1016/j.aca.2016.11.049] |
| 21. Li Zeng, Guowen Zhang, Yijing Liao, Deming Gong. (2016) Inhibitory mechanism of morin on α-glucosidase and its anti-glycation properties. Food & Function, 7 (9): (3953-3963). [PMID:27549567] [10.1039/C6FO00680A] |
| 22. Suyun Lin, Guowen Zhang, Yijing Liao, Junhui Pan, Deming Gong. (2015) Dietary Flavonoids as Xanthine Oxidase Inhibitors: Structure–Affinity and Structure–Activity Relationships. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:26285120] [10.1021/acs.jafc.5b03386] |
| 23. Xiaodan Liu, Xia Wu. (2014) Fluorescence enhancement of fisetin by silver nanoparticles with cetyltrimethyl ammonium bromide micelles. RSC Advances, 5 (10): (7433-7439). [10.1039/C4RA12726A] |
| 24. Bowen Xiao, Huijuan Wang, Xijuan Zhao, Yuanfang Li. (2014) Selective recognition of luteolin and quercetin based on the specific interaction of ortho-dihydroxy substituents with a zinc(II) complex. Analytical Methods, 6 (9): (2894-2899). [10.1039/C4AY00066H] |
| 25. Li-Feng Li, Meng-Di Wang, Chen-Yang Zhang, Meng-Yao Jin, Hua-Lei Chen, Huan Luo, Tian-Yu Hou, Zhi-Jun Zhang, He Li. (2025) Influence of hydroxyl substitution on the inhibition of flavonoids in advanced glycation end-products formation in glucose-lysine-arginine Maillard reaction models. FOOD RESEARCH INTERNATIONAL, [PMID:40086959] [10.1016/j.foodres.2025.116068] |
| 26. Ling-Fang Xu, Zhong-Sheng Tang, Qing-Hui Wen, Xin-An Zeng, Charles Brennan, Debao Niu. (2019) Effects of pulsed electric fields pretreatment on the quality of jujube wine. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 54 (11): (3109-3117). [10.1111/ijfs.14226] |
溶液计算器
常见问题
本产品的纯度是多少？如何测定？
本产品的纯度为 ≥90%，采用高效液相色谱（HPLC）测定。批次的具体数值以分析证书（COA）为准。
「Moligand?」是什么？
「Moligand?」是阿拉丁科学的高端产品线之一，专为多个工作流程中的高纯度应用而设计。与同类工作流程中的标准级别相比，「Moligand?」产品通常具有更严格的规格、更严谨的 QC 以及更强的批间一致性。
本产品应如何储存？
请于?20 °C条件下保存。需冷冻保存以维持规定的有效期。
本产品如何运输？
本产品采用保温箱配冰袋运输。收货后请立即拆包，并按上述储存条件保存。
本产品的 CAS 号、分子式和分子量是多少？
本产品的 CAS 号为 480-16-0，分子式为 C15H10O7，分子量为 302.24 g/mol。InChIKey YXOLAZRVSSWPPT-UHFFFAOYSA-N。
如何获取批次专用COA？
每个订单都会随附分析证书（COA），您也可以从账户订单历史中下载。如需订购前的COA，请联系您的客户代表，或使用PDP上的"申请COA"按钮——我们将提供代表性批次的COA。
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