G2615117计算溶液所需的质量、体积或浓度。
2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱（PAPC）
有货
为什么选择此级别
提供 ≥95% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
-80℃储存。特低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱是在sn-1和sn-2位置包含棕榈酸和花生四烯酸的磷脂。2-花生四烯酸-1-棕榈酰-sn-甘油-3-磷酸胆碱可以天然存在于生物膜中。在体内，2-花生四烯基-1-棕榈酰基-sn-甘油-3-磷酸胆碱被氧化，其产物参与慢性炎症和血管疾病。2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱已用于氧化磷脂信号的研究。分离的人骨髓瘤细胞显示2-花生四烯酰基-1-棕榈酰基-sn-甘油-3-磷酸胆碱水平降低。
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is a phospholipid that contains palmitic acid and arachidonic acid at the sn-1 and sn-2 positions. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine can be found naturally in biological membranes. In vivo, 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine is oxidized, and its products are involved in chronic inflammation and vascular disease. 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine has been utilized in the studies of oxidized phospholipid signaling. Isolated human myeloma cells showed decreased levels of 2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine.
product description：
Phosphatidylcholine (PC) is one of the major glycerophospholipids of the eukaryotic membranes. PC is zwitterionic. PC is synthesized via two pathways in higher eukaryotes like the triple methylation of phosphatidylethanolamine and the cytidine diphosphate (CDP)-choline pathway.
application：
16:0-20:4 PC is suitable for use:
in the preparation of auto-oxidised phospholipid for electrospray ionisation mass spectroscopic (ESI-MS) analysis
in liposome preparation for the treatment of organoid
as antigen in enzyme linked immunosorbent assay (ELISA) for the detection of autoantibodies to phospholipids
Biochemical/Physiological Effects：
Phosphatidylcholine (PC) is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol. PC is the dominant phospholipid present in cancer and neo-neoplastic tissues. Level of 16:0-20:4 PC is less in multiple myeloma cells than in normal plasma cells.
规格
英文别名
PAPC | 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine | 16:0-20:4 PC | PC(16:0/20:4(5Z,8Z,11Z,14Z)) | PC(16:0/20:4) | 1-Palmitoyl-2-Arachidonoyl-sn-glycero-3-PC
规格或纯度
≥95%, A solution in chloroform
英文名称
2-Arachidonoyl-1-palmitoyl-sn-glycero-3-phosphocholine (PAPC)
储存条件
-80℃储存
运输条件
特低温运输
纯度
≥95%
名称和识别符
分子类型
小分子
IUPAC Name
[(2R)-2-hexadecanoyloxy-3-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoyl]oxypropyl] 2-(trimethylazaniumyl)ethyl phosphate
INCHI
1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-21-22-23-25-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-24-19-17-15-13-11-9-7-2/h14,16,20-21,23,25,28,30,42H,6-13,15,17-19,22,24,26-27,29,31-41H2,1-5H3/b16-14-,21-20-,25-23-,30-28-/t42-/m1/s1
InChi Key
PUDHBQQGURLBGJ-IVFHWKNFSA-N
Smiles
O=C(CCCCCCCCCCCCCCC)OC[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O
Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)O[C@H](COC(=O)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)COP(=O)([O-])OCC[N+](C)(C)C
分子量
782.08
Reaxy-Rn
56934292
Reaxys-RN link address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=56934292&ln=
技术文档
高级数据
化学和物理性质
溶解性
Soluble in chloroform.
安全和危险性（GHS）
预防措施声明
P264: 处理后要彻底洗手。
质检证书（CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
溶液计算器
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