AMXI-5001 is a potent, orally active, and dual parp1/2 and microtubule polymerization inhibitor. MXI-5001 exhibits selective antitumor cytotoxicity across a wide variety of human cancer cells with much lower IC 50 s than existing clinical PARP1/2 inhibitors. AMXI-5001 induces complete regression of established tumors, including exceedingly large tumors.
Form:Solid
规格
规格或纯度
≥98%
英文名称
AMXI-5001
生化机理
AMXI-5001 是一种强效的口服活性 PARP1/2 和微管聚合双重抑制剂。MXI-5001 对多种人类癌细胞具有选择性抗肿瘤细胞毒性,其 IC 50 s 远低于现有的临床 PARP1/2 抑制剂。