Rat anti Mouse BST2/CD317 Antibody, Monoclonal (927), could be used for in vivo pDC depletion, ICC/IF, Flow and so on. Application: Flow: Use at an assay dependent concentration. ICC/IF: Use at an assay dependent concentration. in vivo pDC depletion: Use at an assay dependent concentration. Protein Function May be involved in the sorting of secreted proteins (By similarity). May be involved in pre-B-cell growth. Antiretroviral defense protein, that blocks release of retrovirus from the cell surface. Depleted unpon HIV-1 infection by viral VPU protein through 20S proteasome degradation. Depleted upon infection by human Kaposi's sarcoma-associated herpesvirus (KSHV) through ubiquitination and subsequent degradation. May play a role in B-cell activation in rheumatoid arthritis.
BST2/CD317 Rat mAb (Ab091771) - Flow Cytometry Multicolor flow cytometric analysis of BST2/CD317 expression on live mouse splenocytes. C57Bl/6 mouse splenocytes were stained with CD45R Rat mAb (PE-Cy7) (Ab191673), CD11c Armenian Hamster mAb (FITC) (Ab178874) and either Rat IgG (AF647) (Ab190071; Left panel) or BST2/CD317 Rat mAb (Ab091771; Right panel) conjugated with AF647 at 0.4 μg/mL for 1 hour at 4°C. A bivariate pseudocolor density plot showing the correlated expression of BST2/CD317 expression (or Isotype control staining) was derived from CD45R positive gated events with the forward and side light-scatter characteristics of viable thymocytes.