Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
宿主种属
大鼠(Rat)
特异性
CD11b
种属反应性
人(Human),小鼠(Mouse)
免疫原
C57BL/10 splenocytes
阳性对照
Flow Cytometry: Human peripheral blood granulocyte
偶联
Unconjugated
备注
此产品可替代 Ab210604
克隆类型
单克隆抗体
克隆号
M1/70
Format
Whole IgG
亚型
Rat IgG2b
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 7.2-7.4
防腐剂
No
储存条件
2-8°C储存
运输条件
低温运输
稳定性与储存
4°C 下运输。4°C 长期保存（12 个月）。收货后建议分装。
图片
CD11b Rat mAb (Ab093718) - Flow Cytometry Flow Cytometry analysis of THP-1 cells labelling CD11b (red) with CD11b Rat mAb (Ab093718) at 0.1 μg/mL for 1 hour at 4°C. Goat anti-Rat IgG (H+L) AF488 at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, mouse IgG (Ab170221). Black - Unlabelled control, cells without incubation with primary antibody.
ZJ24F0505987
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