PBS Only,已验证,无叠氮钠,无载体 级 提供 ≥95%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
2-8°C储存,禁止冷冻。低温运输,禁止冷冻 。请查阅批次 COA 获取详细规格。
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rat anti Mouse CD31 Antibody, Monoclonal (390), could be used for Flow, ICC/IF, Intravital imaging, in vivo CD31 blocking and so on.
Application
Flow: Use at an assay dependent concentration.
ICC/IF: Use at an assay dependent concentration.
Intravital imaging: Use at an assay dependent concentration.
in vivo CD31 blocking: Use at an assay dependent concentration.
Protein Function
Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).
CD31 Rat mAb (Ab094526) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD31 with CD31 Rat mAb (Ab094526) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
CD31 Rat mAb (Ab094526) - Flow Cytometry
Flow Cytometry analysis of mouse splenocytes cells labelling CD31 (red) with CD31 Rat mAb (Ab094526) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
Use at an assay dependent concentration.
Use at an assay dependent concentration.
Use at an assay dependent concentration.
Use at an assay dependent concentration.
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0707936 |
分析证书 | Ab094526 |
| ZJ24F0707937 |
分析证书 | Ab094526 |
| ZJ24F0707938 |
分析证书 | Ab094526 |
| ZJ25F0218529 |
分析证书 | Ab094526 |
| ZJ25F0218530 |
分析证书 | Ab094526 |
| ZJ25F0218531 |
分析证书 | Ab094526 |
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