carcinoembryonicantibody | Carcinoembryonic antigen CGM1 antibody | Carcinoembryonic antigen gene family member 1 antibody | carcinoembryonic antigen related cell adhesion molecule 3 antibody | Carcinoembryonic antigen-related cell adhesion molecule 3 ant
规格或纯度
见COA
生化机理
Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis.
Post-translational: Tyrosine-phosphorylated in response to microbial binding. Tyr-230 and Tyr-241 are both required for phosphorylation to be detected.
宿主种属
兔(Rabbit)
特异性
CEACAM3
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CEACAM3.
阳性对照
WB: Mouse lung lysates. IHC: Human gastric cancer, thyroid cancer tissues.