Rat anti Mouse CD278/ICOS Antibody, Monoclonal (7E.17G9), could be used for in vivo blocking of ICOS/ICOSL signaling, Flow and so on. Application Flow: Use at an assay dependent concentration. in vivo blocking of ICOS/ICOSL signaling: Use at an assay dependent concentration. Protein Function Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
Mouse ICOS cDNA and ICOS hexahistidine fusion protein
偶联
Unconjugated
克隆类型
单克隆抗体
克隆号
7E.17G9
Format
Whole IgG
亚型
Rat IgG2b
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 8.0
储存条件
2-8°C储存,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
4°C 下运输。4°C 长期保存（12 个月）。请勿冷冻。收货后建议分装。
图片
CD278/ICOS Rat mAb (Ab109273) - Flow Cytometry Two-color flow cytometric analysis of CD278/ICOS expression on mouse splenocytes. Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) C57BL/6 mouse spleen cells were stained with CD4 Rat mAb (FITC) (Ab181110) and CD278/ICOS Rat mAb (Ab109273) at 0.5 μg/mL. Two-color flow cytometric dot plots showing the correlated expression of CD4 versus CD278/ICOS (or Isotype control staining) were derived from gated events with the forward and side light-scatter characteristics of viable mononuclear cells.
ZJ24F0708831
危险品化学品经营许可证（带存储）