Rat anti Mouse/Human Integrin alpha 4/CD49D Antibody, Monoclonal (PS/2), could be used for Flow, in vivo VLA-4 neutralization, in vitro VLA-4 neutralization and so on. Application: Flow: Use at an assay dependent concentration. in vivo VLA-4 neutralization: Use at an assay dependent concentration. in vitro VLA-4 neutralization: Use at an assay dependent concentration. Protein Function Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
CD49D | 269C wild type | CD49 antigen-like family member D | CD49d antigen | CD49d | CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor | IA4 | Integrin alpha 4 | integrin alpha-4 subunit | integrin alpha-4 | Integrin alpha-IV | integrin, alpha 4 (anti
规格或纯度
无载体,无叠氮钠,已验证,PBS Only,≥95%(SDS-PAGE),见COA
宿主种属
大鼠(Rat)
特异性
Integrin alpha 4/CD49D
种属反应性
人(Human),小鼠(Mouse)
免疫原
Mouse P815 mast cells
偶联
Unconjugated
克隆类型
单克隆抗体
克隆号
PS/2
Format
Whole IgG
亚型
Rat IgG2b
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBS, pH 6.5
储存条件
2-8°C储存,禁止冷冻
运输条件
低温运输,禁止冷冻
稳定性与储存
4°C 下运输。4°C 长期保存（12 个月）。请勿冷冻。收货后建议分装。
图片
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin (right panel) at 0.5 μg/mL for 1 hour at 4°C, compared with Rat IgG Isotype Control Antibody (Biotin) (Ab180310) (left panel) and detected with SA-PE (rp156150).
Integrin alpha 4/CD49D Rat mAb (Ab110790) - Flow Cytometry Flow Cytometry analysis of human peripheral blood lymphocytes labelling Integrin alpha 4/CD49D (red) with Integrin alpha 4/CD49D Rat mAb (Ab110790) conjugated with biotin at 0.5 μg/mL for 1 hour at 4°C, and detected with SA-PE (rp156150). Blue - Rat IgG Isotype Control Antibody (Biotin) (Ab180310). Black - Unlabelled control, cells without incubation with primary antibody.
ZJ24F0607434
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