ACSB antibody | ACSVL6 antibody | BA CoA ligase antibody | BA-CoA ligase antibody | BACS antibody | BAL antibody | Bile acid CoA ligase antibody | Bile acid-CoA ligase antibody | Bile acyl CoA synthetase antibody | Bile acyl-CoA synthetase antibody | Chol
规格或纯度
见COA
生化机理
Acyl-CoA synthetase involved in bile acid metabolism. Proposed to catalyze the first step in the conjugation of C24 bile acids (choloneates) to glycine and taurine before excretion into bile canaliculi by activating them to their CoA thioesters. Seems to activate secondary bile acids entering the liver from the enterohepatic circulation. In vitro, also activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol.
宿主种属
兔(Rabbit)
特异性
SLC27A5
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human SLC27A5.
阳性对照
WB: Mouse liver lysates. IHC: Human liver tissues.