ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥90%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Polatuzumab vedotin-piiq (anti-CD79b) 是一种靶向 CD79b 的抗体活性分子偶联物。它由一种人源化抗 CD79b IgG1 单克隆抗体与一种有效的微管抑制剂单甲基 auristatin E (MMAE) 相连，是一种有效的微管抑制剂。Polatuzumab vedotin-piiq (anti-CD79b) 具有研究大 B 细胞淋巴瘤 (LBCL) 的潜力。
Polatuzumab vedotin-piiq (anti-CD79b) is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. Polatuzumab vedotin-piiq (anti-CD79b) has the potential for the research of Large B-cell lymphomas (LBCL).
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD79b with Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) conjugated with biotin (right panel) compared with Human IgG (Biotin) (Ab180314) - Isotype Control (left panel) and detected with SA-PE (rp156150).
Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - SEC
The purity of Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) is more than 95% verified by HPLC.
Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - ELISA
Immobilized Recombinant Human CD79B protein (rp144109) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.
Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) - Flow Cytometry
Flow Cytometry analysis of human peripheral blood lymphocytes labelling CD79b (red) with Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) conjugated with biotin and detected with SA-PE (rp156150). Blue - Isotype control, Human IgG (Biotin) (Ab180314). Black - Unlabelled control, cells without incubation with primary antibody.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1114127 |
分析证书 | Ab175635 |
| ZJ24F1114128 |
分析证书 | Ab175635 |
| ZJ24F1114129 |
分析证书 | Ab175635 |
| ZJ24F0607170 |
分析证书 | Ab175635 |
| ZJ24F0607171 |
分析证书 | Ab175635 |
| ZJ24F0607172 |
分析证书 | Ab175635 |
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查看 Animal Free 级别指南 → 查看 Carrier Free 级别指南 → 查看 Recombinant 级别指南 → 查看 Validated 级别指南 → 查看 ExactAb™ 级别指南 → 查看 Low Endotoxin 级别指南 → 查看 Azide Free 级别指南 →
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