ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥90%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Datopotamab deruxtecan (anti-TROP2) 是一种滋养层细胞表面抗原 2 (TROP2) 导向的抗体活性分子偶联物 (ADC)。Datopotamab deruxtecan (anti-TROP2) 具有强大的抗肿瘤活性。
Datopotamab deruxtecan (anti-TROP2) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan (anti-TROP2) has a potent antitumor activity.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Datopotamab deruxtecan (anti-TROP2) (Ab183314) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling TROP2 (red) with Datopotamab deruxtecan (anti-TROP2) (Ab183314). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Datopotamab deruxtecan (anti-TROP2) (Ab183314) - ELISA
Immobilized rhTROP2(ECD)-chis at 2.0 μg/mL can bind Datopotamab deruxtecan (anti-TROP2) (Ab183314) with the EC
₅₀
of 7.22 ng/mL.
Datopotamab deruxtecan (anti-TROP2) (Ab183314) - HIC
The drug-to-antibody ratio (DAR) of the Datopotamab deruxtecan (anti-TROP2) (Ab183314) is 4.0.
The purity of Datopotamab deruxtecan (anti-TROP2) (Ab183314) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1215427 |
分析证书 | Ab183314 |
| ZJ24F0505657 |
分析证书 | Ab183314 |
| ZJ24F0505658 |
分析证书 | Ab183314 |
| ZJ24F0505659 |
分析证书 | Ab183314 |
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