ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥90%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Farletuzumab-MMAE (anti-FOLR1) 是一种抗体药物偶联物 (ADC)，由人源化抗人叶酸受体-α (FRα) 和细胞毒性剂单甲基 auristatin (MMAE) 通过 MC-Vc 连接体组成。 它具有有效的抗肿瘤活性。
Farletuzumab-MMAE (anti-FOLR1) is an antibody-drug conjugate (ADC) composed of humanized anti-human folate receptor-alpha (FRα) and the cytotoxic agent monomethyl auristatin (MMAE) via a MC-Vc linker. It has a potent antitumor activity.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - Flow Cytometry
Flow Cytometry analysis of Hela cells labelling FOLR1 (red) with Farletuzumab-MMAE (anti-FOLR1) (Ab183319). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling FOLR1 (red) with Farletuzumab-MMAE (anti-FOLR1) (Ab183319). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - SEC
The purity of Farletuzumab-MMAE (anti-FOLR1) (Ab183319) is more than 95% verified by HPLC.
Farletuzumab-MMAE (anti-FOLR1) (Ab183319) - ELISA
Immobilized Recombinant Human FOLR1 protein (rp167844) at 1.0 μg/mL can bind Farletuzumab-MMAE (anti-FOLR1) (Ab183319) with the EC₅₀ of 36.63 ng/mL.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0607212 |
分析证书 | Ab183319 |
| ZJ24F0607213 |
分析证书 | Ab183319 |
| ZJ24F0607214 |
分析证书 | Ab183319 |
我们的级别选择指南涵盖了目录中所有的变体的纯度、稳定剂状态和应用适用性。
查看 Animal Free 级别指南 → 查看 Carrier Free 级别指南 → 查看 Recombinant 级别指南 → 查看 Validated 级别指南 → 查看 ExactAb™ 级别指南 → 查看 Low Endotoxin 级别指南 → 查看 Azide Free 级别指南 →
危险品化学品经营许可证（带存储）