ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥90%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
-80℃储存,避免反复冻融。特低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Enapotamab vedotin (anti-Axl) 是一种AXL 特异性人 IgG1 抗体，通过蛋白酶可裂解的缬氨酸与微管破坏剂单甲基 auristatin E (MMAE) 结合-瓜氨酸 (vc) 连接子。
Enapotamab vedotin (anti-Axl) is an AXL-specific human IgG1 antibody conjugated to the microtubule disrupting agent monomethyl auristatin E (MMAE) through a protease cleavable valine-citrulline (vc) linker.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Enapotamab vedotin (anti-Axl) (Ab183333) - Flow Cytometry
Flow Cytometry analysis of HeLa cells labelling Axl (red) with Enapotamab vedotin (anti-Axl) (Ab183333) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Enapotamab vedotin (anti-Axl) (Ab183333) - Flow Cytometry
Flow Cytometry analysis of U-2 OS cells labelling Axl (red) with Enapotamab vedotin (anti-Axl) (Ab183333) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Enapotamab vedotin (anti-Axl) (Ab183333) - ELISA
Immobilized Recombinant Human Axl protein (rp183600) at 1.0 μg/mL can bind Enapotamab vedotin (anti-Axl) (Ab183333) with the EC₅₀ of 28.23 ng/mL.
Enapotamab vedotin (anti-Axl) (Ab183333) - SEC
The purity of Enapotamab vedotin (anti-Axl) (Ab183333) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1216103 |
分析证书 | Ab183333 |
| ZJ24F1216104 |
分析证书 | Ab183333 |
| ZJ24F1216105 |
分析证书 | Ab183333 |
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