Synthesizes cyclic ADP-ribose (cADPR), a second messenger for glucose-induced insulin secretion.Synthesizes the Ca2+ mobilizer nicotinate-adenine dinucleotide phosphate, NAADP+, from 2'-phospho-cADPR and nicotinic acid, as well as from NADP+ and nicotinic acid. At both pH 5.0 and pH 7.4 preferentially transforms 2'-phospho-cADPR into NAADP+, while preferentially cleaving NADP+ to cADPR and ADPRP rather than into NADDP+.Has cADPR hydrolase activity.
宿主种属
小鼠(Mouse)
特异性
Human CD38
种属反应性
人(Human)
免疫原
Recombinant protein corresponding to Human CD38
阳性对照
Flow Cytometry: Raji cells
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
1.0 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.2
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃(1-2周);长期储存-20℃(24个月);收货后建议分装,避免反复冻融。
图片
CD38 Mouse mAb (Ab184717) - Flow Cytometry
Overlay histogram showing Jurkat cells stained with CD38 Mouse mAb (Ab184717) (Red) at 1.25 μg/mL for 1 hour at 4°C. The Goat Anti-Mouse IgG H&L (PE) (Ab179006) was used as the secondary antibody. Unlabeled sample (Black) was used as a negative control. Mouse IgG1-kappa, anti-E8L (Ab213557) was used as an isotype control (Blue).