Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion .
Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion.
In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration.
In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles.
Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption.
Acts as a receptor for PSG17 .
Involved in platelet activation and aggregation.
Regulates paranodal junction formation.
Involved in cell adhesion, cell motility and tumor metastasis.
Palmitoylated at a low, basal level in unstimulated platelets. The level of palmitoylation increases when platelets are activated by thrombin (in vitro). The protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.
Palmitoylation by ZDHHC2 regulates CD9 expression, association with other tetraspanin family proteins and function in cell adhesion.
宿主种属
小鼠(Mouse)
特异性
Human CD9
种属反应性
人(Human)
免疫原
Recombinant protein corresponding to Human CD9
阳性对照
Flow Cytometry: MCF-7 cells
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
1.0 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.2
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
图片
CD9 Mouse mAb (Ab187864) - Flow Cytometry
Overlay histogram showing MCF-7 cells stained with CD9 Mouse mAb (Ab187864) (Red) at 1.25 μg/mL for 1 hour at 4°C. The Goat Anti-Mouse IgG H&L (PE) (Ab179006) was used as the secondary antibody. Unlabeled sample (Black) was used as a negative control. Mouse IgG1-kappa, anti-E8L (Ab213557) was used as an isotype control (Blue).
ZJ26F0131225
危险品化学品经营许可证（带存储）