Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
宿主种属
小鼠(Mouse)
特异性
Human CYCS
种属反应性
人(Human)
预测反应种属
Pan troglodytes
免疫原
Recombinant protein corresponding to Human CYCS
阳性对照
WB: SH-SY-5Y; HepG2; HeLa; Jurkat; K562; LNCaP
偶联
Unconjugated
克隆类型
单克隆抗体
Format
Whole IgG
轻链亚型
kappa
纯化方法
Protein A purified
浓度
1.0 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
储存缓冲液
PBS, pH 7.2
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
短期储存2-8℃（1-2周）；长期储存-20℃（24个月）；收货后建议分装，避免反复冻融。
图片
Cytochrome c Mouse mAb (Ab215054) - Western Blot All lanes: Cytochrome c Mouse Antibody (Ab215054) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution Predicted band size: 11 kDa Observed band size: 15 kDa Exposure time: 30.0 s
ZJ25F0927900
危险品化学品经营许可证（带存储）