Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways.
Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif.
Binding generally results in the modulation of the activity of the binding partner.
Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB.
Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation.
In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity).
14-3-3 zeta Mouse mAb (Ab221829) - Western Blot All lanes: 14-3-3 zeta Mouse Antibody (Ab221829) at 1/10000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution Predicted band size: 28 kDa Observed band size: 28 kDa Exposure time: 30.0 s